Bicycle Therapeutics's ROE % for the quarter that ended in Mar. 2026 was -42.07%. Bicycle Therapeutics's PB Ratio for the quarter that ended in Mar. 2026 was 0.54.
Bicycle Therapeutics's ROE % Adjusted to Book Value for the quarter that ended in Mar. 2026 was -77.91%.
Bicycle Therapeutics ROE % Adjusted to Book Value Related Terms
Bicycle Therapeutics ROE % Adjusted to Book Value Historical Data
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The historical data trend for Bicycle Therapeutics's ROE % Adjusted to Book Value can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Bicycle Therapeutics ROE % Adjusted to Book Value Chart
FRA:50BA vs IFRX, ELDN, ZNTL: ROE % Adjusted to Book Value Comparison
For the Biotechnology subindustry, Bicycle Therapeutics's ROE % Adjusted to Book Value, along with its competitors' market caps and ROE % Adjusted to Book Value data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
Bicycle Therapeutics ROE % Adjusted to Book Value vs Biotechnology Industry
For the Biotechnology industry and Healthcare sector, Bicycle Therapeutics's ROE % Adjusted to Book Value distribution charts can be found below:
* The bar in red indicates where Bicycle Therapeutics's ROE % Adjusted to Book Value falls into.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
What does a ROE % Adjusted to Book Value of -77.91% mean?
Bicycle Therapeutics (FRA:50BA) has a ROE % Adjusted to Book Value of -77.91% as of Mar. 2026. Return on equity adjusted to book is the ratio of return on equity to price-book ratio. View historical data on Bicycle Therapeutics and its competitors.
Is Bicycle Therapeutics' ROE % Adjusted to Book Value too high?
Bicycle Therapeutics' current ROE % Adjusted to Book Value is -77.91%. Overall, Bicycle Therapeutics has a GF Score™ of 56/100 and is considered Possible Value Trap, reflecting its overall financial health beyond just this single metric.
How does Bicycle Therapeutics' ROE % Adjusted to Book Value compare to IFRX and ELDN?
Bicycle Therapeutics' ROE % Adjusted to Book Value of -77.91% can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good ROE % Adjusted to Book Value for a Biotechnology company?
A good ROE % Adjusted to Book Value depends on the Biotechnology industry context. However, ROE % Adjusted to Book Value should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high ROE % Adjusted to Book Value mean?
A high ROE % Adjusted to Book Value can signal that a stock is expensive relative to its fundamentals. Return on equity adjusted to book is the ratio of return on equity to price-book ratio. View historical data on Bicycle Therapeutics and its competitors. Bicycle Therapeutics's current ROE % Adjusted to Book Value is -77.91%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Bicycle Therapeutics stock overvalued right now?
Based on GuruFocus' analysis, Bicycle Therapeutics (FRA:50BA) is currently considered Possible Value Trap. The stock's GF Value™ is €12.39, compared to a current price of €3.52 — trading 71.6% below its estimated fair value. The current ROE % Adjusted to Book Value is -77.91%. Bicycle Therapeutics' overall GF Score™ is 56/100 with 5 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is ROE % Adjusted to Book Value calculated?
ROE % Adjusted to Book Value is calculated from a company's financial statements. For Bicycle Therapeutics (FRA:50BA), the current ROE % Adjusted to Book Value is -77.91% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Is Bicycle Therapeutics (FRA:50BA) Overvalued in 2026?
Based on GuruFocus' analysis, Bicycle Therapeutics stock appears to be undervalued.
The current stock price of €3.52 is trading 71.6% below its estimated GF Value™ of €12.39.
GuruFocus considers Bicycle Therapeutics to be Possible Value Trap.
Key valuation signals for FRA:50BA:
ROE % Adjusted to Book Value: -77.91%
GF Value™: €12.39 vs. price of €3.52 (71.6% below fair value)
No single metric tells the full story. See the FRA:50BA stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.
Bicycle Therapeutics PLC is a clinical-stage biopharmaceutical company developing a novel class of medicines which are referred to as Bicycles. The Bicycles are synthetic short peptides constrained to form two loops that stabilize their structural geometry. Its initial internal programs are focused on oncology indications with high unmet medical needs. The company's product candidate, BT1718, is a Bicycle Toxin Conjugate, or BTC. The company has two segments: the United Kingdom and the United States. It derives maximum revenue from United Kingdom.
56GF Score
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