HALO (Halozyme Therapeutics) ROE % Adjusted to Book Value: 12.82% (As of Mar. 2026)


HALO Halozyme Therapeutics Inc HALO
92 GF Score
Price $77.18
GF Value $90.32
Valuation Modestly Undervalued
! 3 Warning Signs
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What is Halozyme Therapeutics ROE % Adjusted to Book Value?

Halozyme Therapeutics HALO +2.96% 92 ROE % Adjusted to Book Value is 12.82% as of Mar. 2026. GuruFocus rates HALO with a GF Score™ of 92/100 and a GF Value™ of $90.32 (Modestly Undervalued). The stock has 3 warning signs investors should review.

Halozyme Therapeutics's ROE % for the quarter that ended in Mar. 2026 was 447.16%. Halozyme Therapeutics's PB Ratio for the quarter that ended in Mar. 2026 was 34.88. Halozyme Therapeutics's ROE % Adjusted to Book Value for the quarter that ended in Mar. 2026 was 12.82%.


Halozyme Therapeutics ROE % Adjusted to Book Value Related Terms


Halozyme Therapeutics ROE % Adjusted to Book Value Historical Data

* Premium members only.

The historical data trend for Halozyme Therapeutics's ROE % Adjusted to Book Value can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Halozyme Therapeutics ROE % Adjusted to Book Value Chart

Halozyme Therapeutics Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
ROE % Adjusted to Book Value
Get a 7-Day Free Trial Premium Member Only Premium Member Only 8.24 2.43 3.97 12.26 0.94

Halozyme Therapeutics Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
ROE % Adjusted to Book Value Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 6.85 8.82 9.80 -1.26 12.82

HALO vs KYMR, IBRX, PRAX: ROE % Adjusted to Book Value Comparison

For the Biotechnology subindustry, Halozyme Therapeutics's ROE % Adjusted to Book Value, along with its competitors' market caps and ROE % Adjusted to Book Value data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Halozyme Therapeutics ROE % Adjusted to Book Value vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Halozyme Therapeutics's ROE % Adjusted to Book Value distribution charts can be found below:

* The bar in red indicates where Halozyme Therapeutics's ROE % Adjusted to Book Value falls into.


HALO
92GF Score
Halozyme Therapeutics Inc HALO
ROE % Adjusted to Book Value is just one metric. See GF Score™, valuation, warning signs, and more.
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Halozyme Therapeutics ROE % Adjusted to Book Value Calculation

Halozyme Therapeutics's ROE % Adjusted to Book Value for the fiscal year that ended in Dec. 2025 is calculated as

ROE % Adjusted to Book Value=ROE % / PB Ratio
=153.59% / 162.56
=0.94%

Halozyme Therapeutics's ROE % Adjusted to Book Value for the quarter that ended in Mar. 2026 is calculated as

ROE % Adjusted to Book Value=ROE % / PB Ratio
=447.16% / 34.88
=12.82%

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

What does a ROE % Adjusted to Book Value of 12.82% mean?
Halozyme Therapeutics (HALO) has a ROE % Adjusted to Book Value of 12.82% as of Mar. 2026. Return on equity adjusted to book is the ratio of return on equity to price-book ratio. View historical data on Halozyme Therapeutics and its competitors.
Is Halozyme Therapeutics' ROE % Adjusted to Book Value too high?
Halozyme Therapeutics' current ROE % Adjusted to Book Value is 12.82%. Overall, Halozyme Therapeutics has a GF Score™ of 92/100 and is considered Modestly Undervalued, reflecting its overall financial health beyond just this single metric.
How does Halozyme Therapeutics' ROE % Adjusted to Book Value compare to KYMR and IBRX?
Halozyme Therapeutics' ROE % Adjusted to Book Value of 12.82% can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good ROE % Adjusted to Book Value for a Biotechnology company?
A good ROE % Adjusted to Book Value depends on the Biotechnology industry context. However, ROE % Adjusted to Book Value should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high ROE % Adjusted to Book Value mean?
A high ROE % Adjusted to Book Value can signal that a stock is expensive relative to its fundamentals. Return on equity adjusted to book is the ratio of return on equity to price-book ratio. View historical data on Halozyme Therapeutics and its competitors. Halozyme Therapeutics's current ROE % Adjusted to Book Value is 12.82%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Halozyme Therapeutics stock overvalued right now?
Based on GuruFocus' analysis, Halozyme Therapeutics (HALO) is currently considered Modestly Undervalued. The stock's GF Value™ is $90.32, compared to a current price of $77.18 — trading 14.5% below its estimated fair value. The current ROE % Adjusted to Book Value is 12.82%. Halozyme Therapeutics' overall GF Score™ is 92/100 with 3 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is ROE % Adjusted to Book Value calculated?
ROE % Adjusted to Book Value is calculated from a company's financial statements. For Halozyme Therapeutics (HALO), the current ROE % Adjusted to Book Value is 12.82% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Halozyme Therapeutics (HALO) Overvalued in 2026?

Based on GuruFocus' analysis, Halozyme Therapeutics stock appears to be undervalued. The current stock price of $77.18 is trading 14.5% below its estimated GF Value™ of $90.32. GuruFocus considers Halozyme Therapeutics to be Modestly Undervalued.

Key valuation signals for HALO:

  • ROE % Adjusted to Book Value: 12.82%
  • GF Value™: $90.32 vs. price of $77.18 (14.5% below fair value)
  • GF Score™: 92/100 with 3 warning signs

No single metric tells the full story. See the HALO stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Halozyme Therapeutics Business Description

Address 12390 El Camino Real, San Diego, CA, USA, 92130
Halozyme Therapeutics Inc is a biotechnology company focused on developing and commercializing novel oncology therapies. The company seeks to create therapies focused on human enzymes that alter tumors. Halozyme focuses on developing its proprietary products in therapeutic areas with a focus on oncology, and licensing its technology to biopharmaceutical companies to collaboratively develop products. ENHANZE drug delivery technology was introduced with the proprietary enzyme rHuPH20, to facilitate the subcutaneous delivery of injected drugs and fluids, with the goal of improving the patient experience with rapid SC delivery and reduced treatment burden. The company's operations are based in the United States, with minimal long-lived assets located internationally.
92GF Score

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ROE % Adjusted to Book Value is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$77.18
Price
$90.32
GF Value