HALO (Halozyme Therapeutics) Piotroski F-Score: 5 (As of Jun. 28, 2026) — Near Median


HALO Halozyme Therapeutics Inc HALO
92 GF Score
Price $74.96
GF Value $90.32
Valuation Modestly Undervalued
! 3 Warning Signs
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What is Halozyme Therapeutics Piotroski F-Score?

Halozyme Therapeutics HALO +3.19% 92 Piotroski F-Score is 5 as of Jun. 28, 2026, which is at its 10-year median of 5.00. GuruFocus rates HALO with a GF Score™ of 92/100 and a GF Value™ of $90.32 (Modestly Undervalued). The stock has 3 warning signs investors should review. Among 1,342 Biotechnology companies, Halozyme Therapeutics ranks better than 85.1% on this metric.

The zones of discrimination were as such:

Good or high score = 7, 8, 9
Bad or low score = 0, 1, 2, 3

Halozyme Therapeutics has an F-score of 5 indicating the company's financial situation is typical for a stable company.

The historical rank and industry rank for Halozyme Therapeutics's Piotroski F-Score or its related term are showing as below:

HALO' s Piotroski F-Score Range Over the Past 10 Years
Min: 2   Med: 5   Max: 9
Current: 5

During the past 13 years, the highest Piotroski F-Score of Halozyme Therapeutics was 9. The lowest was 2. And the median was 5.

Halozyme Therapeutics  (NAS:HALO) Piotroski F-Score Explanation

The developer of the system is Joseph D. Piotroski is relatively unknown accounting professor who shuns publicity and rarely gives interviews.

He graduated from the University of Illinois with a B.S. in accounting in 1989, received an M.B.A. from Indiana University in 1994. Five years later, in 1999, after earning a Ph.D. in accounting from the University of Michigan, he became an associate professor of accounting at the University of Chicago.

In 2000, he wrote a research paper called "Value Investing: The Use of Historical Financial Statement Information to Separate Winners from Losers" (pdf).

He wanted to see if he can develop a system (using a simple nine-point scoring system) that can increase the returns of a strategy of investing in low price to book (referred to in the paper as high book to market) value companies.

What he found was something that exceeded his most optimistic expectations.

Buying only those companies that scored highest (8 or 9) on his nine-point scale, or F-Score as he called it, over the 20 year period from 1976 to 1996 led to an average out-performance over the market of 13.4%.

Even more impressive were the results of a strategy of investing in the highest F-Score companies (8 or 9) and shorting companies with the lowest F-Score (0 or 1).

Over the same period from 1976 to 1996 (20 years) this strategy led to an average yearly return of 23%, substantially outperforming the average S&P 500 index return of 15.83% over the same period.


Halozyme Therapeutics Piotroski F-Score Related Terms


Halozyme Therapeutics Piotroski F-Score Historical Data

* Premium members only.

The historical data trend for Halozyme Therapeutics's Piotroski F-Score can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Halozyme Therapeutics Piotroski F-Score Chart

Halozyme Therapeutics Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Piotroski F-Score
Get a 7-Day Free Trial Premium Member Only Premium Member Only 6.00 4.00 6.00 9.00 5.00

Halozyme Therapeutics Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
Piotroski F-Score Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 9.00 8.00 8.00 5.00 5.00

HALO vs IBRX, TECH, CORT: Piotroski F-Score Comparison

For the Biotechnology subindustry, Halozyme Therapeutics's Piotroski F-Score, along with its competitors' market caps and Piotroski F-Score data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Halozyme Therapeutics Piotroski F-Score vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Halozyme Therapeutics's Piotroski F-Score distribution charts can be found below:

* The bar in red indicates where Halozyme Therapeutics's Piotroski F-Score falls into.


HALO
92GF Score
Halozyme Therapeutics Inc HALO
Piotroski F-Score is just one metric. See GF Score™, valuation, warning signs, and more.
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How is the Piotroski F-Score calculated?

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

This Year (Mar26) TTM:Last Year (Mar25) TTM:
Net Income was 165.16 + 175.225 + -141.591 + 150.049 = $349 Mil.
Cash Flow from Operations was 99.711 + 178.597 + 219.029 + 180.078 = $677 Mil.
Revenue was 325.719 + 354.264 + 451.767 + 376.708 = $1,508 Mil.
Gross Profit was 279.36 + 299.022 + 372.997 + 297.47 = $1,249 Mil.
Average Total Assets from the begining of this year (Mar25)
to the end of this year (Mar26) was
(2196.532 + 2053.899 + 2221.232 + 2525.323 + 2672.719) / 5 = $2333.941 Mil.
Total Assets at the begining of this year (Mar25) was $2,197 Mil.
Long-Term Debt & Capital Lease Obligation was $1,936 Mil.
Total Current Assets was $1,003 Mil.
Total Current Liabilities was $363 Mil.
Net Income was 93.245 + 137.011 + 137.012 + 118.095 = $485 Mil.

Revenue was 231.353 + 290.084 + 298.008 + 264.861 = $1,084 Mil.
Gross Profit was 191.746 + 240.658 + 255.953 + 216.458 = $905 Mil.
Average Total Assets from the begining of last year (Mar24)
to the end of last year (Mar25) was
(1841.527 + 1969.453 + 2118.03 + 2063.477 + 2196.532) / 5 = $2037.8038 Mil.
Total Assets at the begining of last year (Mar24) was $1,842 Mil.
Long-Term Debt & Capital Lease Obligation was $1,507 Mil.
Total Current Assets was $1,262 Mil.
Total Current Liabilities was $150 Mil.

*Note: If the latest quarterly/semi-annual/annual total assets data is 0, then we will use previous quarterly/semi-annual/annual data for all the items in the balance sheet.

Profitability

Question 1. Return on Assets (ROA)

Net income before extraordinary items for the year divided by Total Assets at the beginning of the year.

Score 1 if positive, 0 if negative.

Halozyme Therapeutics's current Net Income (TTM) was 349. ==> Positive ==> Score 1.

Question 2. Cash Flow Return on Assets (CFROA)

Net cash flow from operating activities (operating cash flow) divided by Total Assets at the beginning of the year.

Score 1 if positive, 0 if negative.

Halozyme Therapeutics's current Cash Flow from Operations (TTM) was 677. ==> Positive ==> Score 1.

Question 3. Change in Return on Assets

Compare this year's return on assets (1) to last year's return on assets.

Score 1 if it's higher, 0 if it's lower.

ROA (This Year)=Net Income/Total Assets (Mar25)
=348.843/2196.532
=0.15881535

ROA (Last Year)=Net Income/Total Assets (Mar24)
=485.363/1841.527
=0.26356551

Halozyme Therapeutics's return on assets of this year was 0.15881535. Halozyme Therapeutics's return on assets of last year was 0.26356551. ==> Last year is higher ==> Score 0.

Question 4. Quality of Earnings (Accrual)

Compare Cash flow return on assets (2) to return on assets (1)

Score 1 if CFROA > ROA, 0 if CFROA <= ROA.

Halozyme Therapeutics's current Net Income (TTM) was 349. Halozyme Therapeutics's current Cash Flow from Operations (TTM) was 677. ==> 677 > 349 ==> CFROA > ROA ==> Score 1.

Funding

Question 5. Change in Gearing or Leverage

Compare this year's gearing (long-term debt divided by average total assets) to last year's gearing.

Score 0 if this year's gearing is higher, 1 otherwise.

Gearing (This Year: Mar26)=Long-Term Debt & Capital Lease Obligation/Average Total Assets from Mar25 to Mar26
=1935.896/2333.941
=0.8294537

Gearing (Last Year: Mar25)=Long-Term Debt & Capital Lease Obligation/Average Total Assets from Mar24 to Mar25
=1507.447/2037.8038
=0.73974099

Halozyme Therapeutics's gearing of this year was 0.8294537. Halozyme Therapeutics's gearing of last year was 0.73974099. ==> Last year is lower than this year ==> Score 0.

Question 6. Change in Working Capital (Liquidity)

Compare this year's current ratio (current assets divided by current liabilities) to last year's current ratio.

Score 1 if this year's current ratio is higher, 0 if it's lower

Current Ratio (This Year: Mar26)=Total Current Assets/Total Current Liabilities
=1003.036/363.21
=2.76158696

Current Ratio (Last Year: Mar25)=Total Current Assets/Total Current Liabilities
=1262.028/150.379
=8.39231542

Halozyme Therapeutics's current ratio of this year was 2.76158696. Halozyme Therapeutics's current ratio of last year was 8.39231542. ==> Last year's current ratio is higher ==> Score 0.

Question 7. Change in Shares in Issue

Compare the number of shares in issue this year, to the number in issue last year.

Score 0 if there is larger number of shares in issue this year, 1 otherwise.

Halozyme Therapeutics's number of shares in issue this year was 122.875. Halozyme Therapeutics's number of shares in issue last year was 126.644. ==> There is smaller number of shares in issue this year, or the same. ==> Score 1.

Efficiency

Question 8. Change in Gross Margin

Compare this year's gross margin (Gross Profit divided by sales) to last year's.

Score 1 if this year's gross margin is higher, 0 if it's lower.

Gross Margin (This Year: TTM)=Gross Profit/Revenue
=1248.849/1508.458
=0.82789776

Gross Margin (Last Year: TTM)=Gross Profit/Revenue
=904.815/1084.306
=0.83446463

Halozyme Therapeutics's gross margin of this year was 0.82789776. Halozyme Therapeutics's gross margin of last year was 0.83446463. ==> Last year's gross margin is higher ==> Score 0.

Question 9. Change in asset turnover

Compare this year's asset turnover (total sales for the year divided by total assets at the beginning of the year) to last year's asset turnover ratio.

Score 1 if this year's asset turnover ratio is higher, 0 if it's lower

Asset Turnover (This Year)=Revenue/Total Assets at the Beginning of This Year (Mar25)
=1508.458/2196.532
=0.68674529

Asset Turnover (Last Year)=Revenue/Total Assets at the Beginning of Last Year (Mar24)
=1084.306/1841.527
=0.58880809

Halozyme Therapeutics's asset turnover of this year was 0.68674529. Halozyme Therapeutics's asset turnover of last year was 0.58880809. ==> This year's asset turnover is higher. ==> Score 1.

Evaluation

Piotroski F-Score= Que. 1+ Que. 2+ Que. 3+Que. 4+Que. 5+Que. 6+Que. 7+Que. 8+Que. 9
=1+1+0+1+0+0+1+0+1
=5

Good or high score = 7, 8, 9
Bad or low score = 0, 1, 2, 3

Halozyme Therapeutics has an F-score of 5 indicating the company's financial situation is typical for a stable company.

Frequently Asked Questions Learn more about Piotroski F-Score →
What does a Piotroski F-Score of 5 mean?
Halozyme Therapeutics (HALO) has a Piotroski F-Score of 5 as of Jun. 28, 2026. The Piotroski F-score grades a company's business operating strength from 0-9. View historical data on Halozyme Therapeutics and its competitors. This is near median its historical median of 5.00. Over the past decade, Halozyme Therapeutics' Piotroski F-Score has ranged from 2.00 to 9.00. According to the industry distribution chart, Halozyme Therapeutics ranks #200 out of 1342 companies in the Biotechnology industry, placing it in the top 14.9%.
Is Halozyme Therapeutics' Piotroski F-Score too high?
Halozyme Therapeutics' current Piotroski F-Score of 5 is near median its 10-year median of 5.00. Over the past 10 years, this metric has ranged from a low of 2.00 to a high of 9.00. The Biotechnology industry median Piotroski F-Score is 3.00. Halozyme Therapeutics' value of 5 is 66.7% above this industry median. Based on the distribution chart, Halozyme Therapeutics ranks #200 out of 1342 companies in the Biotechnology industry, which is in the top quartile — a strong position relative to peers. Overall, Halozyme Therapeutics has a GF Score™ of 92/100 and is considered Modestly Undervalued, reflecting its overall financial health beyond just this single metric.
How does Halozyme Therapeutics' Piotroski F-Score compare to IBRX and TECH?
According to the Biotechnology industry distribution chart, Halozyme Therapeutics ranks #200 out of 1342 companies for Piotroski F-Score. This places Halozyme Therapeutics in the top 15% of its industry — outperforming the majority of peers. The industry median Piotroski F-Score is 3.00. Halozyme Therapeutics' value of 5 is 66.7% above this benchmark. Historically, Halozyme Therapeutics' own Piotroski F-Score has ranged from 2.00 to 9.00 over the past decade. While the company's 10-year median is 5.00 vs. the industry median of 3.00, Halozyme Therapeutics has consistently been above the industry average. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Piotroski F-Score for a Biotechnology company?
The median Piotroski F-Score among Biotechnology companies is 3.00, based on 1,342 companies in the industry. Companies in the top quartile (top 25%) have a Piotroski F-Score significantly above this median, while those in the bottom quartile fall well below. However, Piotroski F-Score should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Halozyme Therapeutics's current Piotroski F-Score of 5 is 66.7% above the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Piotroski F-Score mean?
A high Piotroski F-Score can signal that a stock is expensive relative to its fundamentals. The Piotroski F-score grades a company's business operating strength from 0-9. View historical data on Halozyme Therapeutics and its competitors. For the Biotechnology industry, the median Piotroski F-Score is 3.00 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Halozyme Therapeutics's current Piotroski F-Score is 5, which is near median its own 10-year median of 5.00. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Halozyme Therapeutics stock overvalued right now?
Based on GuruFocus' analysis, Halozyme Therapeutics (HALO) is currently considered Modestly Undervalued. The stock's GF Value™ is $90.32, compared to a current price of $74.96 — trading 17% below its estimated fair value. The current Piotroski F-Score is 5, which is near median its 10-year median of 5.00 and 66.7% above the Biotechnology industry median of 3.00. Halozyme Therapeutics' overall GF Score™ is 92/100 with 3 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Piotroski F-Score calculated?
Piotroski F-Score is calculated from a company's financial statements. For Halozyme Therapeutics (HALO), the current Piotroski F-Score is 5 as of Jun. 28, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Halozyme Therapeutics (HALO) Overvalued in 2026?

Based on GuruFocus' analysis, Halozyme Therapeutics stock appears to be undervalued. The current stock price of $74.96 is trading 17% below its estimated GF Value™ of $90.32. GuruFocus considers Halozyme Therapeutics to be Modestly Undervalued.

Key valuation signals for HALO:

  • Piotroski F-Score: 5 (near median its 10-year median of 5.00)
  • GF Value™: $90.32 vs. price of $74.96 (17% below fair value)
  • GF Score™: 92/100 with 3 warning signs
  • Industry Position: 66.7% above the Biotechnology median (#200 of 1342)

No single metric tells the full story. See the HALO stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Halozyme Therapeutics Business Description

Address 12390 El Camino Real, San Diego, CA, USA, 92130
Halozyme Therapeutics Inc is a biotechnology company focused on developing and commercializing novel oncology therapies. The company seeks to create therapies focused on human enzymes that alter tumors. Halozyme focuses on developing its proprietary products in therapeutic areas with a focus on oncology, and licensing its technology to biopharmaceutical companies to collaboratively develop products. ENHANZE drug delivery technology was introduced with the proprietary enzyme rHuPH20, to facilitate the subcutaneous delivery of injected drugs and fluids, with the goal of improving the patient experience with rapid SC delivery and reduced treatment burden. The company's operations are based in the United States, with minimal long-lived assets located internationally.
92GF Score

Get the complete analysis for HALO

Piotroski F-Score is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$74.96
Price
$90.32
GF Value