Aptamer Group (STU:P0J) ROE % Adjusted to Book Value: -12.49% (As of Dec. 2025)

Author: Vera Yuan Vera Yuan
Vera Yuan
Vera Yuan
Director of Data and Quant Analytics at GuruFocus
Focused on building reliable datasets, financial models, and research tools for value-minded investors. Committed to turning complex data into practical guidance for value-investing and long-term wealth.
Reviewed by: Charlie Tian Charlie Tian
Charlie Tian
Charlie Tian
Founder & CEO of GuruFocus
Dr. Charlie Tian is the founder and CEO of GuruFocus.com, a leading global investment research platform established in 2004. With a Ph.D. in physics, Dr. Tian transitioned from science to finance, applying a data-driven, disciplined approach to value investing.

What is Aptamer Group ROE % Adjusted to Book Value?

Aptamer Group STU:P0J ROE % Adjusted to Book Value is -12.49% as of Dec. 2025. The stock has 4 warning signs investors should review.

Aptamer Group's ROE % for the quarter that ended in Dec. 2025 was -124.89%. Aptamer Group's PB Ratio for the quarter that ended in Dec. 2025 was 10.00. Aptamer Group's ROE % Adjusted to Book Value for the quarter that ended in Dec. 2025 was -12.49%.

Aptamer Group ROE % Adjusted to Book Value Related Terms

Aptamer Group ROE % Adjusted to Book Value Historical Data

* Premium members only.

The historical data trend for Aptamer Group's ROE % Adjusted to Book Value can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Aptamer Group ROE % Adjusted to Book Value Chart

Aptamer Group Annual Data
Trend Mar19 Mar20 Jun22 Jun23 Jun24 Jun25
ROE % Adjusted to Book Value
Get a 7-Day Free Trial 0.00 -6.54 -12.94 -199.49 -85.32

Aptamer Group Semi-Annual Data
Mar19 Mar20 Dec21 Jun22 Dec22 Jun23 Dec23 Jun24 Dec24 Jun25 Dec25
ROE % Adjusted to Book Value Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only -131.19 -64.80 -86.49 -52.32 -12.49

STU:P0J vs VRTX, REGN, RVMD: ROE % Adjusted to Book Value Comparison

For the Biotechnology subindustry, Aptamer Group's ROE % Adjusted to Book Value, along with its competitors' market caps and ROE % Adjusted to Book Value data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.

Aptamer Group ROE % Adjusted to Book Value vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Aptamer Group's ROE % Adjusted to Book Value distribution charts can be found below:

* The bar in red indicates where Aptamer Group's ROE % Adjusted to Book Value falls into.


Aptamer Group ROE % Adjusted to Book Value Calculation

Aptamer Group's ROE % Adjusted to Book Value for the fiscal year that ended in Jun. 2025 is calculated as

ROE % Adjusted to Book Value=ROE % / PB Ratio
=-213.31% / 2.50
=-85.32%

Aptamer Group's ROE % Adjusted to Book Value for the quarter that ended in Dec. 2025 is calculated as

ROE % Adjusted to Book Value=ROE % / PB Ratio
=-124.89% / 10.00
=-12.49%

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

What does a ROE % Adjusted to Book Value of -12.49% mean?
Aptamer Group (STU:P0J) has a ROE % Adjusted to Book Value of -12.49% as of Dec. 2025. Return on equity adjusted to book is the ratio of return on equity to price-book ratio. View historical data on Aptamer Group and its competitors.
Is Aptamer Group's ROE % Adjusted to Book Value too high?
Aptamer Group's current ROE % Adjusted to Book Value is -12.49%.
How does Aptamer Group's ROE % Adjusted to Book Value compare to VRTX and REGN?
Aptamer Group's ROE % Adjusted to Book Value of -12.49% can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good ROE % Adjusted to Book Value for a Biotechnology company?
A good ROE % Adjusted to Book Value depends on the Biotechnology industry context. However, ROE % Adjusted to Book Value should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high ROE % Adjusted to Book Value mean?
A high ROE % Adjusted to Book Value can signal that a stock is expensive relative to its fundamentals. Return on equity adjusted to book is the ratio of return on equity to price-book ratio. View historical data on Aptamer Group and its competitors. Aptamer Group's current ROE % Adjusted to Book Value is -12.49%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Aptamer Group stock overvalued right now?
Aptamer Group (STU:P0J) has a current ROE % Adjusted to Book Value of -12.49%. The current ROE % Adjusted to Book Value is -12.49%. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is ROE % Adjusted to Book Value calculated?
ROE % Adjusted to Book Value is calculated from a company's financial statements. For Aptamer Group (STU:P0J), the current ROE % Adjusted to Book Value is -12.49% as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Aptamer Group Business Description

Other Exchanges APTA:UKP0J:Germany
Address Innovation Way, Windmill House, York, GBR, YO10 5BR
Aptamer Group PLC provides Optimer binders for use in research, diagnostics and therapeutics. It strives to deliver transformational solutions that meet the needs of researchers and developers across the life sciences through the use of its proprietary Optimer technology. Its businesses, Aptamer Solutions for custom Optimer development, Aptamer Diagnostics for in-house and collaborative Optimer-based diagnostic development and Aptamer Therapeutics for the development of Optimer-based therapeutics. The Group represents a single operating segment being research and experimental development of biotechnology. It operates in United Kingdom, Europe, USA and others.