vTv Therapeutics (FRA:5VT0) ROE %: 125.72% (As of Mar. 2026)


FRA:5VT0 vTv Therapeutics Inc FRA:5VT0
35 GF Score
Price €30.80
GF Value €6,657.81
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What is vTv Therapeutics ROE %?

vTv Therapeutics FRA:5VT0 +1.32% 35 ROE % is 125.72% as of Mar. 2026. GuruFocus rates FRA:5VT0 with a GF Score™ of 35/100 and a GF Value™ of €6,657.81. Among 1,255 Biotechnology companies, vTv Therapeutics ranks better than 83.43% on this metric.

ROE % is calculated as Net Income divided by its average Total Stockholders Equity over a certain period of time. vTv Therapeutics's annualized net income for the quarter that ended in Mar. 2026 was €83.50 Mil. vTv Therapeutics's average Total Stockholders Equity over the quarter that ended in Mar. 2026 was €66.42 Mil. Therefore, vTv Therapeutics's annualized ROE % for the quarter that ended in Mar. 2026 was 125.72%.

The historical rank and industry rank for vTv Therapeutics's ROE % or its related term are showing as below:

FRA:5VT0' s ROE % Range Over the Past 10 Years
Min: -70.4   Med: -70.4   Max: 4.78
Current: 4.78

During the past 13 years, vTv Therapeutics's highest ROE % was 4.78%. The lowest was -70.40%. And the median was -70.40%.

FRA:5VT0's ROE % is ranked better than
83.43% of 1255 companies
in the Biotechnology industry
Industry Median: -38.18 vs FRA:5VT0: 4.78

vTv Therapeutics  (FRA:5VT0) ROE % Explanation

ROE % measures the rate of return on the ownership interest (shareholder's equity) of the common stock owners. It measures a firm's efficiency at generating profits from every unit of shareholders' equity (also known as net assets or assets minus liabilities). ROE % shows how well a company uses investment funds to generate earnings growth. ROE %s between 15% and 20% are considered desirable.

The factors that affect a company's ROE % can be illustrated with the three-step DuPont Analysis:

ROE %(Q: Mar. 2026 )
=Net Income/Total Stockholders Equity
=83.504/66.422
=(Net Income / Revenue )*(Revenue / Total Assets)*(Total Assets / Total Stockholders Equity)
=(83.504 / 127.464)*(127.464 / 81.1235)*(81.1235 / 66.422)
=Net Margin %*Asset Turnover*Equity Multiplier
=65.51 %*1.5712*1.2213
=ROA %*Equity Multiplier
=102.93 %*1.2213
=125.72 %

With this breakdown, it is clear that if a company grows its Net Profit Margin, its Asset Turnover, or its Leverage, it can grow its ROE %.

The factors that affect a company's ROE % can also be illustrated with the five-step DuPont Analysis:

ROE %(Q: Mar. 2026 )
=Net Income/Total Stockholders Equity
=83.504/66.422
=(Net Income / Pre-Tax Income) * (Pre-Tax Income / Operating Income) * (Operating Income / Revenue) * (Revenue / Total Assets) * (Total Assets / Total Stockholders Equity)
= (83.504 / 83.504) * (83.504 / 80.488) * (80.488 / 127.464) * (127.464 / 81.1235) * (81.1235 / 66.422)
= Tax Burden * Interest Burden * Operating Margin % * Asset Turnover * Equity Multiplier
= 1 * 1.0375 * 63.15 % * 1.5712 * 1.2213
=125.72 %

Note: The net income data used here is four times the quarterly (Mar. 2026) net income data. The Revenue data used here is four times the quarterly (Mar. 2026) revenue data. The same rule applies to Pre-Tax Income and Operating Income.
* In the five-step DuPont Analysis, Operating Income is only available for non-financial companies. Thus, for Insurance companies, we use EBIT as a substitution of Operating Income. For Banks, both Operating Income and EBIT is unavailable. Thus we combined Interest Burden and Operating Margin % into Pretax Margin %, and the DuPont Analysis is divided into four components instead.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.


Be Aware

Net Income is used.

Because a company can increase its ROE % by having more financial leverage, it is important to watch the equity multiplier when investing in high ROE % companies. Like ROA %, ROE % is calculated with only 12 months data. Fluctuations in company's earnings or business cycles can affect the ratio drastically. It is important to look at the ratio from a long term perspective.

Asset light businesses require very few assets to generate very high earnings. Their ROE %s can be extremely high.


vTv Therapeutics ROE % Related Terms


vTv Therapeutics ROE % Historical Data

* Premium members only.

The historical data trend for vTv Therapeutics's ROE % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

vTv Therapeutics ROE % Chart

vTv Therapeutics Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
ROE %
Get a 7-Day Free Trial Premium Member Only Premium Member Only 0.00 0.00 0.00 0.00 -69.10

vTv Therapeutics Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
ROE % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -198.57 -431.40 -94.86 -42.36 125.72

FRA:5VT0 vs CRDF, GUTS, ACOG: ROE % Comparison

For the Biotechnology subindustry, vTv Therapeutics's ROE %, along with its competitors' market caps and ROE % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


vTv Therapeutics ROE % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, vTv Therapeutics's ROE % distribution charts can be found below:

* The bar in red indicates where vTv Therapeutics's ROE % falls into.


FRA:5VT0
35GF Score
vTv Therapeutics Inc FRA:5VT0
ROE % is just one metric. See GF Score™, valuation, warning signs, and more.
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vTv Therapeutics ROE % Calculation

vTv Therapeutics's annualized ROE % for the fiscal year that ended in Dec. 2025 is calculated as

ROE %=Net Income (A: Dec. 2025 )/( (Total Stockholders Equity (A: Dec. 2024 )+Total Stockholders Equity (A: Dec. 2025 ))/ count )
=-23.036/( (11.65+55.029)/ 2 )
=-23.036/33.3395
=-69.10 %

vTv Therapeutics's annualized ROE % for the quarter that ended in Mar. 2026 is calculated as

ROE %=Net Income (Q: Mar. 2026 )/( (Total Stockholders Equity (Q: Dec. 2025 )+Total Stockholders Equity (Q: Mar. 2026 ))/ count )
=83.504/( (55.029+77.815)/ 2 )
=83.504/66.422
=125.72 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

In the calculation of annual ROE %, the net income of the last fiscal year and the average total shareholder equity over the fiscal year are used. In calculating the quarterly data, the net income data used here is four times the quarterly (Mar. 2026) net income data. ROE % is displayed in the 30-year financial page.

Frequently Asked Questions Learn more about ROE % →
What does a ROE % of 125.72% mean?
vTv Therapeutics (FRA:5VT0) has a ROE % of 125.72% as of Mar. 2026. Return on equity is the ratio of current-period net income to average two-period total equity. View historical data on vTv Therapeutics and its competitors. According to the industry distribution chart, vTv Therapeutics ranks #208 out of 1255 companies in the Biotechnology industry, placing it in the top 16.6%.
Is vTv Therapeutics' ROE % too high?
vTv Therapeutics' current ROE % is 125.72%. Based on the distribution chart, vTv Therapeutics ranks #208 out of 1255 companies in the Biotechnology industry, which is in the top quartile — a strong position relative to peers. Overall, vTv Therapeutics has a GF Score™ of 35/100, reflecting its overall financial health beyond just this single metric.
How does vTv Therapeutics' ROE % compare to CRDF and GUTS?
According to the Biotechnology industry distribution chart, vTv Therapeutics ranks #208 out of 1255 companies for ROE %. This places vTv Therapeutics in the top 17% of its industry — outperforming the majority of peers. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good ROE % for a Biotechnology company?
A good ROE % depends on the Biotechnology industry context. However, ROE % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high ROE % mean?
A high ROE % can signal that a stock is expensive relative to its fundamentals. Return on equity is the ratio of current-period net income to average two-period total equity. View historical data on vTv Therapeutics and its competitors. vTv Therapeutics's current ROE % is 125.72%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is vTv Therapeutics stock overvalued right now?
vTv Therapeutics (FRA:5VT0) has a current ROE % of 125.72%. The stock's GF Value™ is €6,657.81, compared to a current price of €30.80 — trading 99.5% below its estimated fair value. The current ROE % is 125.72%. vTv Therapeutics' overall GF Score™ is 35/100. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is ROE % calculated?
ROE % is calculated from a company's financial statements. For vTv Therapeutics (FRA:5VT0), the current ROE % is 125.72% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is vTv Therapeutics (FRA:5VT0) Overvalued in 2026?

Based on GuruFocus' analysis, vTv Therapeutics stock appears to be undervalued. The current stock price of €30.80 is trading 99.5% below its estimated GF Value™ of €6,657.81.

Key valuation signals for FRA:5VT0:

  • ROE %: 125.72%
  • GF Value™: €6,657.81 vs. price of €30.80 (99.5% below fair value)
  • GF Score™: 35/100

No single metric tells the full story. See the FRA:5VT0 stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


vTv Therapeutics Business Description

Other Exchanges VTVT:USA
Address 3980 Premier Drive, Suite 110, High Point, NC, USA, 27265
vTv Therapeutics Inc is a late-stage biopharmaceutical company focused on developing oral, small-molecule drug candidates intended to help treat people living with diabetes and other chronic diseases. Its clinical pipeline is led by cadisegliatin (TTP399), a novel, small-molecule, liver-selective glucokinase activator (GKA) currently being evaluated as a potential oral adjunctive therapy to insulin for the treatment of type 1 diabetes (T1D). In addition, the company is also engaged in the research and development of other candidates in its pipeline through collaborations with academic partners and license agreements, which include TTP273, HPP737, TTP-RA, Mavodelpar (HPP593), HPP971, and HPP3033, being studied and developed to counter various chronic diseases.
35GF Score

Get the complete analysis for FRA:5VT0

ROE % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

€30.80
Price
€6,657.81
GF Value