IKT (Inhibikase Therapeutics) ROE %: -38.48% (As of Mar. 2026)


IKT Inhibikase Therapeutics Inc IKT
36 GF Score
Price $1.87
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What is Inhibikase Therapeutics ROE %?

Inhibikase Therapeutics IKT -1.06% 36 ROE % is -38.48% as of Mar. 2026. GuruFocus rates IKT with a GF Score™ of 36/100. The stock has 1 warning sign investors should review. Among 1,256 Biotechnology companies, Inhibikase Therapeutics ranks worse than 53.11% on this metric.

ROE % is calculated as Net Income divided by its average Total Stockholders Equity over a certain period of time. Inhibikase Therapeutics's annualized net income for the quarter that ended in Mar. 2026 was $-65.52 Mil. Inhibikase Therapeutics's average Total Stockholders Equity over the quarter that ended in Mar. 2026 was $170.26 Mil. Therefore, Inhibikase Therapeutics's annualized ROE % for the quarter that ended in Mar. 2026 was -38.48%.

The historical rank and industry rank for Inhibikase Therapeutics's ROE % or its related term are showing as below:

IKT' s ROE % Range Over the Past 10 Years
Min: -118.88   Med: -61.05   Max: -36.05
Current: -43.99

During the past 8 years, Inhibikase Therapeutics's highest ROE % was -36.05%. The lowest was -118.88%. And the median was -61.05%.

IKT's ROE % is ranked worse than
53.11% of 1256 companies
in the Biotechnology industry
Industry Median: -38.26 vs IKT: -43.99

Inhibikase Therapeutics  (NAS:IKT) ROE % Explanation

ROE % measures the rate of return on the ownership interest (shareholder's equity) of the common stock owners. It measures a firm's efficiency at generating profits from every unit of shareholders' equity (also known as net assets or assets minus liabilities). ROE % shows how well a company uses investment funds to generate earnings growth. ROE %s between 15% and 20% are considered desirable.

The factors that affect a company's ROE % can be illustrated with the three-step DuPont Analysis:

ROE %(Q: Mar. 2026 )
=Net Income/Total Stockholders Equity
=-65.524/170.262
=(Net Income / Revenue )*(Revenue / Total Assets)*(Total Assets / Total Stockholders Equity)
=(-65.524 / 0)*(0 / 177.2685)*(177.2685 / 170.262)
=Net Margin %*Asset Turnover*Equity Multiplier
=N/A %*0*1.0412
=ROA %*Equity Multiplier
=N/A %*1.0412
=-38.48 %

With this breakdown, it is clear that if a company grows its Net Profit Margin, its Asset Turnover, or its Leverage, it can grow its ROE %.

The factors that affect a company's ROE % can also be illustrated with the five-step DuPont Analysis:

ROE %(Q: Mar. 2026 )
=Net Income/Total Stockholders Equity
=-65.524/170.262
=(Net Income / Pre-Tax Income) * (Pre-Tax Income / Operating Income) * (Operating Income / Revenue) * (Revenue / Total Assets) * (Total Assets / Total Stockholders Equity)
= (-65.524 / -65.524) * (-65.524 / -72.86) * (-72.86 / 0) * (0 / 177.2685) * (177.2685 / 170.262)
= Tax Burden * Interest Burden * Operating Margin % * Asset Turnover * Equity Multiplier
= 1 * 0.8993 * N/A % * 0 * 1.0412
=-38.48 %

Note: The net income data used here is four times the quarterly (Mar. 2026) net income data. The Revenue data used here is four times the quarterly (Mar. 2026) revenue data. The same rule applies to Pre-Tax Income and Operating Income.
* In the five-step DuPont Analysis, Operating Income is only available for non-financial companies. Thus, for Insurance companies, we use EBIT as a substitution of Operating Income. For Banks, both Operating Income and EBIT is unavailable. Thus we combined Interest Burden and Operating Margin % into Pretax Margin %, and the DuPont Analysis is divided into four components instead.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.


Be Aware

Net Income is used.

Because a company can increase its ROE % by having more financial leverage, it is important to watch the equity multiplier when investing in high ROE % companies. Like ROA %, ROE % is calculated with only 12 months data. Fluctuations in company's earnings or business cycles can affect the ratio drastically. It is important to look at the ratio from a long term perspective.

Asset light businesses require very few assets to generate very high earnings. Their ROE %s can be extremely high.


Inhibikase Therapeutics ROE % Related Terms


Inhibikase Therapeutics ROE % Historical Data

* Premium members only.

The historical data trend for Inhibikase Therapeutics's ROE % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Inhibikase Therapeutics ROE % Chart

Inhibikase Therapeutics Annual Data
Trend Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
ROE %
Get a 7-Day Free Trial -61.35 -60.74 -118.88 -52.00 -36.05

Inhibikase Therapeutics Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
ROE % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -60.59 -47.85 -62.40 -41.45 -38.48

IKT vs NKTX, CAMP, NERV: ROE % Comparison

For the Biotechnology subindustry, Inhibikase Therapeutics's ROE %, along with its competitors' market caps and ROE % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Inhibikase Therapeutics ROE % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Inhibikase Therapeutics's ROE % distribution charts can be found below:

* The bar in red indicates where Inhibikase Therapeutics's ROE % falls into.


IKT
36GF Score
Inhibikase Therapeutics Inc IKT
ROE % is just one metric. See GF Score™, valuation, warning signs, and more.
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Inhibikase Therapeutics ROE % Calculation

Inhibikase Therapeutics's annualized ROE % for the fiscal year that ended in Dec. 2025 is calculated as

ROE %=Net Income (A: Dec. 2025 )/( (Total Stockholders Equity (A: Dec. 2024 )+Total Stockholders Equity (A: Dec. 2025 ))/ count )
=-48.259/( (94.866+172.904)/ 2 )
=-48.259/133.885
=-36.05 %

Inhibikase Therapeutics's annualized ROE % for the quarter that ended in Mar. 2026 is calculated as

ROE %=Net Income (Q: Mar. 2026 )/( (Total Stockholders Equity (Q: Dec. 2025 )+Total Stockholders Equity (Q: Mar. 2026 ))/ count )
=-65.524/( (172.904+167.62)/ 2 )
=-65.524/170.262
=-38.48 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

In the calculation of annual ROE %, the net income of the last fiscal year and the average total shareholder equity over the fiscal year are used. In calculating the quarterly data, the net income data used here is four times the quarterly (Mar. 2026) net income data. ROE % is displayed in the 30-year financial page.

Frequently Asked Questions Learn more about ROE % →
What does a ROE % of -38.48% mean?
Inhibikase Therapeutics (IKT) has a ROE % of -38.48% as of Mar. 2026. Return on equity is the ratio of current-period net income to average two-period total equity. View historical data on Inhibikase Therapeutics and its competitors. According to the industry distribution chart, Inhibikase Therapeutics ranks #667 out of 1256 companies in the Biotechnology industry, placing it in the top 53.1%.
Is Inhibikase Therapeutics' ROE % too high?
Inhibikase Therapeutics' current ROE % is -38.48%. Based on the distribution chart, Inhibikase Therapeutics ranks #667 out of 1256 companies in the Biotechnology industry, which is below the industry midpoint. Overall, Inhibikase Therapeutics has a GF Score™ of 36/100, reflecting its overall financial health beyond just this single metric.
How does Inhibikase Therapeutics' ROE % compare to NKTX and CAMP?
According to the Biotechnology industry distribution chart, Inhibikase Therapeutics ranks #667 out of 1256 companies for ROE %. This places Inhibikase Therapeutics in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good ROE % for a Biotechnology company?
A good ROE % depends on the Biotechnology industry context. However, ROE % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high ROE % mean?
A high ROE % can signal that a stock is expensive relative to its fundamentals. Return on equity is the ratio of current-period net income to average two-period total equity. View historical data on Inhibikase Therapeutics and its competitors. Inhibikase Therapeutics's current ROE % is -38.48%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Inhibikase Therapeutics stock overvalued right now?
Inhibikase Therapeutics (IKT) has a current ROE % of -38.48%. The current ROE % is -38.48%. Inhibikase Therapeutics' overall GF Score™ is 36/100 with 1 warning sign to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is ROE % calculated?
ROE % is calculated from a company's financial statements. For Inhibikase Therapeutics (IKT), the current ROE % is -38.48% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Inhibikase Therapeutics Business Description

Address 1000 N. West Street, Suite 1200, Wilmington, DE, USA, 19801
Inhibikase Therapeutics Inc a clinical-stage pharmaceutical company developing therapeutics to modify the course of cardiopulmonary diseases, namely, Pulmonary Arterial Hypertension (PAH), in which aberrant signaling through type III receptor tyrosine kinases, including platelet derived growth factor receptors and a stem cell factor receptor, known as c-Kit, has been implicated. Its product candidate is IKT-001, a prodrug of imatinib mesylate (imatinib), for PAH which is an orphan indication. The company has developed its own portfolio of protein kinase inhibitors to treat bacterial and viral infections, including viral infections in the brain. It has one reporting segment, which is the business of developing protein kinase inhibitor therapeutics.
36GF Score

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