IKT (Inhibikase Therapeutics) 3-Year ROIIC % : -563.50% (As of Dec. 2025)

Author: Vera Yuan Vera Yuan
Vera Yuan
Vera Yuan
Director of Data and Quant Analytics at GuruFocus
Focused on building reliable datasets, financial models, and research tools for value-minded investors. Committed to turning complex data into practical guidance for value-investing and long-term wealth.
Reviewed by: Charlie Tian Charlie Tian
Charlie Tian
Charlie Tian
Founder & CEO of GuruFocus
Dr. Charlie Tian is the founder and CEO of GuruFocus.com, a leading global investment research platform established in 2004. With a Ph.D. in physics, Dr. Tian transitioned from science to finance, applying a data-driven, disciplined approach to value investing.

IKT Inhibikase Therapeutics Inc IKT
34 GF Score
Price $2.07
! 1 Warning Sign
View Full Analysis

What is Inhibikase Therapeutics 3-Year ROIIC %?

Inhibikase Therapeutics IKT 34 3-Year ROIIC % is -563.50 as of Dec. 2025. GuruFocus rates IKT with a GF Score™ of 34/100. The stock has 1 warning sign investors should review. Among 1,322 Biotechnology companies, Inhibikase Therapeutics ranks worse than 90.24% on this metric.

3-Year Return on Invested Incremental Capital (3-Year ROIIC %) measures the change in earnings as a percentage of change in investment over 3-year. Inhibikase Therapeutics's 3-Year ROIIC % for the quarter that ended in Dec. 2025 was -563.50%. High ROIIC is generally an indication that your business is capital efficient or has a higher operating leverage.

The industry rank for Inhibikase Therapeutics's 3-Year ROIIC % or its related term are showing as below:

IKT's 3-Year ROIIC % is ranked worse than
90.24% of 1322 companies
in the Biotechnology industry
Industry Median: -4.82 vs IKT: -563.50

Inhibikase Therapeutics  (NAS:IKT) 3-Year ROIIC % Explanation

Return on Incremental Invested Capital (ROIIC) is an extension of Return on Investment Capital (ROIC). ROIC % tells investors how efficiently that profitability is earned per dollar of company capital. ROIIC narrows the focus even further and shows how profitable each additional unit of capital investment could be. ROIIC % is a more powerful metric than ROIC because it measures how much money the company can generate going forward on future capital investments.

High ROIIC is generally an indication that your business is capital efficient or has a higher operating leverage.

Be Aware

It's important to keep in mind that when tracking ROIIC, the metric is better suited to forecasting the trend of future returns rather than measuring current return on investment.


Inhibikase Therapeutics 3-Year ROIIC % Related Terms


Inhibikase Therapeutics 3-Year ROIIC % Historical Data

* Premium members only.

The historical data trend for Inhibikase Therapeutics's 3-Year ROIIC % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Inhibikase Therapeutics 3-Year ROIIC % Chart

Inhibikase Therapeutics Annual Data
Trend Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
3-Year ROIIC %
Get a 7-Day Free Trial 890.42 3,453.06 1,343.08 -2,346.86 -563.50

Inhibikase Therapeutics Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
3-Year ROIIC % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 0.00 0.00 0.00 -563.50 0.00

IKT vs FHTX, OBIO, FULC: 3-Year ROIIC % Comparison

For the Biotechnology subindustry, Inhibikase Therapeutics's 3-Year ROIIC %, along with its competitors' market caps and 3-Year ROIIC % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Inhibikase Therapeutics 3-Year ROIIC % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Inhibikase Therapeutics's 3-Year ROIIC % distribution charts can be found below:

* The bar in red indicates where Inhibikase Therapeutics's 3-Year ROIIC % falls into.


IKT
34GF Score
Inhibikase Therapeutics Inc IKT
3-Year ROIIC % is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

Inhibikase Therapeutics 3-Year ROIIC % Calculation

Inhibikase Therapeutics's 3-Year ROIIC % for the quarter that ended in Dec. 2025 is calculated as:

3-Year ROIIC %=3-Year Incremental Net Operating Profit After Taxes (NOPAT)**/3-Year Incremental Invested Capital**
=( -53.348 (Dec. 2025) - -18.129 (Dec. 2022) )/( 7.42 (Dec. 2025) - 1.17 (Dec. 2022) )
=-35.219/6.25
=-563.50%***

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

** Annual data of NOPAT and Invested Capital was used to calculate 3-Year ROIIC %.
*** Please be aware that the ROIIC (Return on Invested Capital) calculations are based on company-level data using the primary share class. The calculated data provided is for demonstration purposes and may slightly differ from the results displayed in the title due to potential variations caused by currency exchange rate differences throughout the year.

Frequently Asked Questions Learn more about 3-Year ROIIC % →
What does a 3-Year ROIIC % of -563.50 mean?
Inhibikase Therapeutics (IKT) has a 3-Year ROIIC % of -563.50 as of Dec. 2025. 3-Year ROIIC % measures the change in earnings as a percentage of change in investment over 3-year. View historical data on Inhibikase Therapeutics and its competitors. According to the industry distribution chart, Inhibikase Therapeutics ranks #1193 out of 1322 companies in the Biotechnology industry, placing it in the top 90.2%.
Is Inhibikase Therapeutics' 3-Year ROIIC % too high?
Inhibikase Therapeutics' current 3-Year ROIIC % is -563.50. Based on the distribution chart, Inhibikase Therapeutics ranks #1193 out of 1322 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, Inhibikase Therapeutics has a GF Score™ of 34/100, reflecting its overall financial health beyond just this single metric.
How does Inhibikase Therapeutics' 3-Year ROIIC % compare to FHTX and OBIO?
According to the Biotechnology industry distribution chart, Inhibikase Therapeutics ranks #1193 out of 1322 companies for 3-Year ROIIC %. This places Inhibikase Therapeutics in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good 3-Year ROIIC % for a Biotechnology company?
A good 3-Year ROIIC % depends on the Biotechnology industry context. However, 3-Year ROIIC % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high 3-Year ROIIC % mean?
A high 3-Year ROIIC % can signal that a stock is expensive relative to its fundamentals. 3-Year ROIIC % measures the change in earnings as a percentage of change in investment over 3-year. View historical data on Inhibikase Therapeutics and its competitors. Inhibikase Therapeutics's current 3-Year ROIIC % is -563.50. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Inhibikase Therapeutics stock overvalued right now?
Inhibikase Therapeutics (IKT) has a current 3-Year ROIIC % of -563.50. The current 3-Year ROIIC % is -563.50. Inhibikase Therapeutics' overall GF Score™ is 34/100 with 1 warning sign to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is 3-Year ROIIC % calculated?
3-Year ROIIC % is calculated from a company's financial statements. For Inhibikase Therapeutics (IKT), the current 3-Year ROIIC % is -563.50 as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Inhibikase Therapeutics Business Description

Address 1000 N. West Street, Suite 1200, Wilmington, DE, USA, 19801
Inhibikase Therapeutics Inc a clinical-stage pharmaceutical company developing therapeutics to modify the course of cardiopulmonary diseases, namely, Pulmonary Arterial Hypertension (PAH), in which aberrant signaling through type III receptor tyrosine kinases, including platelet derived growth factor receptors and a stem cell factor receptor, known as c-Kit, has been implicated. Its product candidate is IKT-001, a prodrug of imatinib mesylate (imatinib), for PAH which is an orphan indication. The company has developed its own portfolio of protein kinase inhibitors to treat bacterial and viral infections, including viral infections in the brain. It has one reporting segment, which is the business of developing protein kinase inhibitor therapeutics.
34GF Score

Get the complete analysis for IKT

3-Year ROIIC % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$2.07
Price