SCNI (Scinai Immunotherapeutics) ROE %: 144.06% (As of Mar. 2026)

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SCNI Scinai Immunotherapeutics Ltd SCNI
20 GF Score
Price $0.23
! 4 Warning Signs
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What is Scinai Immunotherapeutics ROE %?

Scinai Immunotherapeutics SCNI -6.92% 20 ROE % is 144.06% as of Mar. 2026. GuruFocus rates SCNI with a GF Score™ of 20/100. The stock has 4 warning signs investors should review. Among 1,251 Biotechnology companies, Scinai Immunotherapeutics ranks better than 88.97% on this metric.

ROE % is calculated as Net Income divided by its average Total Stockholders Equity over a certain period of time. Scinai Immunotherapeutics's annualized net income for the quarter that ended in Mar. 2026 was $14.31 Mil. Scinai Immunotherapeutics's average Total Stockholders Equity over the quarter that ended in Mar. 2026 was $9.93 Mil. Therefore, Scinai Immunotherapeutics's annualized ROE % for the quarter that ended in Mar. 2026 was 144.06%.

The historical rank and industry rank for Scinai Immunotherapeutics's ROE % or its related term are showing as below:

SCNI' s ROE % Range Over the Past 10 Years
Min: -589.92   Med: -87.03   Max: 177.37
Current: 10.82

During the past 13 years, Scinai Immunotherapeutics's highest ROE % was 177.37%. The lowest was -589.92%. And the median was -87.03%.

SCNI's ROE % is ranked better than
88.97% of 1251 companies
in the Biotechnology industry
Industry Median: -38.61 vs SCNI: 10.82

Scinai Immunotherapeutics  (NAS:SCNI) ROE % Explanation

ROE % measures the rate of return on the ownership interest (shareholder's equity) of the common stock owners. It measures a firm's efficiency at generating profits from every unit of shareholders' equity (also known as net assets or assets minus liabilities). ROE % shows how well a company uses investment funds to generate earnings growth. ROE %s between 15% and 20% are considered desirable.

The factors that affect a company's ROE % can be illustrated with the three-step DuPont Analysis:

ROE %(Q: Mar. 2026 )
=Net Income/Total Stockholders Equity
=14.308/9.932
=(Net Income / Revenue )*(Revenue / Total Assets)*(Total Assets / Total Stockholders Equity)
=(14.308 / 1.956)*(1.956 / 14.607)*(14.607 / 9.932)
=Net Margin %*Asset Turnover*Equity Multiplier
=731.49 %*0.1339*1.4707
=ROA %*Equity Multiplier
=97.95 %*1.4707
=144.06 %

With this breakdown, it is clear that if a company grows its Net Profit Margin, its Asset Turnover, or its Leverage, it can grow its ROE %.

The factors that affect a company's ROE % can also be illustrated with the five-step DuPont Analysis:

ROE %(Q: Mar. 2026 )
=Net Income/Total Stockholders Equity
=14.308/9.932
=(Net Income / Pre-Tax Income) * (Pre-Tax Income / Operating Income) * (Operating Income / Revenue) * (Revenue / Total Assets) * (Total Assets / Total Stockholders Equity)
= (14.308 / 14.308) * (14.308 / -9.868) * (-9.868 / 1.956) * (1.956 / 14.607) * (14.607 / 9.932)
= Tax Burden * Interest Burden * Operating Margin % * Asset Turnover * Equity Multiplier
= 1 * -1.4499 * -504.5 % * 0.1339 * 1.4707
=144.06 %

Note: The net income data used here is four times the quarterly (Mar. 2026) net income data. The Revenue data used here is four times the quarterly (Mar. 2026) revenue data. The same rule applies to Pre-Tax Income and Operating Income.
* In the five-step DuPont Analysis, Operating Income is only available for non-financial companies. Thus, for Insurance companies, we use EBIT as a substitution of Operating Income. For Banks, both Operating Income and EBIT is unavailable. Thus we combined Interest Burden and Operating Margin % into Pretax Margin %, and the DuPont Analysis is divided into four components instead.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.


Be Aware

Net Income is used.

Because a company can increase its ROE % by having more financial leverage, it is important to watch the equity multiplier when investing in high ROE % companies. Like ROA %, ROE % is calculated with only 12 months data. Fluctuations in company's earnings or business cycles can affect the ratio drastically. It is important to look at the ratio from a long term perspective.

Asset light businesses require very few assets to generate very high earnings. Their ROE %s can be extremely high.


Scinai Immunotherapeutics ROE % Related Terms


Scinai Immunotherapeutics ROE % Historical Data

* Premium members only.

The historical data trend for Scinai Immunotherapeutics's ROE % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Scinai Immunotherapeutics ROE % Chart

Scinai Immunotherapeutics Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
ROE %
Get a 7-Day Free Trial Premium Member Only Premium Member Only 0.00 0.00 0.00 177.37 -91.89

Scinai Immunotherapeutics Quarterly Data
Mar21 Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Dec25 Mar26
ROE % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -89.29 -62.42 -131.18 0.00 144.06

SCNI vs ABPO, ISCO, ZVSA: ROE % Comparison

For the Biotechnology subindustry, Scinai Immunotherapeutics's ROE %, along with its competitors' market caps and ROE % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Scinai Immunotherapeutics ROE % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Scinai Immunotherapeutics's ROE % distribution charts can be found below:

* The bar in red indicates where Scinai Immunotherapeutics's ROE % falls into.


SCNI
20GF Score
Scinai Immunotherapeutics Ltd SCNI
ROE % is just one metric. See GF Score™, valuation, warning signs, and more.
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Scinai Immunotherapeutics ROE % Calculation

Scinai Immunotherapeutics's annualized ROE % for the fiscal year that ended in Dec. 2025 is calculated as

ROE %=Net Income (A: Dec. 2025 )/( (Total Stockholders Equity (A: Dec. 2024 )+Total Stockholders Equity (A: Dec. 2025 ))/ count )
=-8.307/( (9.977+8.103)/ 2 )
=-8.307/9.04
=-91.89 %

Scinai Immunotherapeutics's annualized ROE % for the quarter that ended in Mar. 2026 is calculated as

ROE %=Net Income (Q: Mar. 2026 )/( (Total Stockholders Equity (Q: Dec. 2025 )+Total Stockholders Equity (Q: Mar. 2026 ))/ count )
=14.308/( (8.103+11.761)/ 2 )
=14.308/9.932
=144.06 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

In the calculation of annual ROE %, the net income of the last fiscal year and the average total shareholder equity over the fiscal year are used. In calculating the quarterly data, the net income data used here is four times the quarterly (Mar. 2026) net income data. ROE % is displayed in the 30-year financial page.

Frequently Asked Questions Learn more about ROE % →
What does a ROE % of 144.06% mean?
Scinai Immunotherapeutics (SCNI) has a ROE % of 144.06% as of Mar. 2026. Return on equity is the ratio of current-period net income to average two-period total equity. View historical data on Scinai Immunotherapeutics and its competitors. According to the industry distribution chart, Scinai Immunotherapeutics ranks #138 out of 1251 companies in the Biotechnology industry, placing it in the top 11%.
Is Scinai Immunotherapeutics' ROE % too high?
Scinai Immunotherapeutics' current ROE % is 144.06%. Based on the distribution chart, Scinai Immunotherapeutics ranks #138 out of 1251 companies in the Biotechnology industry, which is in the top quartile — a strong position relative to peers. Overall, Scinai Immunotherapeutics has a GF Score™ of 20/100, reflecting its overall financial health beyond just this single metric.
How does Scinai Immunotherapeutics' ROE % compare to ABPO and ISCO?
According to the Biotechnology industry distribution chart, Scinai Immunotherapeutics ranks #138 out of 1251 companies for ROE %. This places Scinai Immunotherapeutics in the top 11% of its industry — outperforming the majority of peers. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good ROE % for a Biotechnology company?
A good ROE % depends on the Biotechnology industry context. However, ROE % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high ROE % mean?
A high ROE % can signal that a stock is expensive relative to its fundamentals. Return on equity is the ratio of current-period net income to average two-period total equity. View historical data on Scinai Immunotherapeutics and its competitors. Scinai Immunotherapeutics's current ROE % is 144.06%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Scinai Immunotherapeutics stock overvalued right now?
Scinai Immunotherapeutics (SCNI) has a current ROE % of 144.06%. The current ROE % is 144.06%. Scinai Immunotherapeutics' overall GF Score™ is 20/100 with 4 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is ROE % calculated?
ROE % is calculated from a company's financial statements. For Scinai Immunotherapeutics (SCNI), the current ROE % is 144.06% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Scinai Immunotherapeutics Business Description

Address Hadassah Ein Kerem Campus, 2nd Floor, Jerusalem BioPark, Jerusalem, ISR
Scinai Immunotherapeutics Ltd is a biopharmaceutical company with two complementary business units: (i) Scinai R&D, focused on the development of therapeutics in inflammation and immunology, and (ii) the contract development and manufacturing organization (CDMO) business. The CDMO business provides integrated development and manufacturing services to small and emerging biotech companies, supporting clients from early-stage development through clinical-stage production.
20GF Score

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ROE % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

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