ARTV (Artiva Biotherapeutics) ROIC %: -469.18% (As of Mar. 2026)


ARTV Artiva Biotherapeutics Inc ARTV
12 GF Score
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What is Artiva Biotherapeutics ROIC %?

Artiva Biotherapeutics ARTV +8.95% 12 ROIC % is -469.18% as of Mar. 2026. GuruFocus rates ARTV with a GF Score™ of 12/100. The stock has 3 warning signs investors should review.

ROIC % measures how well a company generates cash flow relative to the capital it has invested in its business. It is also called ROC %. Artiva Biotherapeutics's annualized return on invested capital (ROIC %) for the quarter that ended in Mar. 2026 was -469.18%.

As of today (2026-06-28), Artiva Biotherapeutics's WACC % is 10.12%. Artiva Biotherapeutics's ROIC % is -406.20% (calculated using TTM income statement data). Artiva Biotherapeutics earns returns that do not match up to its cost of capital. It will destroy value as it grows.


Artiva Biotherapeutics  (NAS:ARTV) ROIC % Explanation

ROIC % measures how well a company generates cash flow relative to the capital it has invested in its business. It is also called ROC %. The reason book values of debt and equity are used is because the book values are the capital the company received when issuing the debt or receiving the equity investments.

There are four key components to this definition. The first is the use of operating income or EBIT rather than net income in the numerator. The second is the tax adjustment to this operating income or EBIT, computed as a hypothetical tax based on an effective or marginal tax rate. The third is the use of book values for invested capital, rather than market values. The final is the timing difference; the capital invested is from the end of the prior year whereas the operating income or EBIT is the current year's number.

Why is ROIC % important?

Because it costs money to raise capital. A firm that generates higher returns on investment than it costs the company to raise the capital needed for that investment is earning excess returns. A firm that expects to continue generating positive excess returns on new investments in the future will see its value increase as growth increases, whereas a firm that earns returns that do not match up to its cost of capital will destroy value as it grows.

As of today, Artiva Biotherapeutics's WACC % is 10.12%. Artiva Biotherapeutics's ROIC % is -406.20% (calculated using TTM income statement data). Artiva Biotherapeutics earns returns that do not match up to its cost of capital. It will destroy value as it grows.


Be Aware

Like ROE % and ROA %, ROIC % is calculated with only 12 months of data. Fluctuations in the company's earnings or business cycles can affect the ratio drastically. It is important to look at the ratio from a long term perspective.


Artiva Biotherapeutics ROIC % Related Terms


Artiva Biotherapeutics ROIC % Historical Data

* Premium members only.

The historical data trend for Artiva Biotherapeutics's ROIC % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Artiva Biotherapeutics ROIC % Chart

Artiva Biotherapeutics Annual Data
Trend Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
ROIC %
Get a 7-Day Free Trial -562.21 -205.87 -85.62 -251.15 -389.67

Artiva Biotherapeutics Quarterly Data
Dec19 Dec20 Mar21 Sep21 Dec21 Mar22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
ROIC % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -356.58 -371.71 -392.89 -398.86 -469.18

ARTV vs ENTA, VNDA, VSTM: ROIC % Comparison

For the Biotechnology subindustry, Artiva Biotherapeutics's ROIC %, along with its competitors' market caps and ROIC % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Artiva Biotherapeutics ROIC % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Artiva Biotherapeutics's ROIC % distribution charts can be found below:

* The bar in red indicates where Artiva Biotherapeutics's ROIC % falls into.


ARTV
12GF Score
Artiva Biotherapeutics Inc ARTV
ROIC % is just one metric. See GF Score™, valuation, warning signs, and more.
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Artiva Biotherapeutics ROIC % Calculation

Artiva Biotherapeutics's annualized Return on Invested Capital (ROIC %) for the fiscal year that ended in Dec. 2025 is calculated as:

ROIC % (A: Dec. 2025 )
=NOPAT/Average Invested Capital
=Operating Income * ( 1 - Tax Rate % )/( (Invested Capital (A: Dec. 2024 ) + Invested Capital (A: Dec. 2025 ))/ count )
=-89.81 * ( 1 - 0% )/( (24.69 + 21.406)/ 2 )
=-89.81/23.048
=-389.67 %

where

Artiva Biotherapeutics's annualized Return on Invested Capital (ROIC %) for the quarter that ended in Mar. 2026 is calculated as:

ROIC % (Q: Mar. 2026 )
=NOPAT/Average Invested Capital
=Operating Income * ( 1 - Tax Rate % )/( (Invested Capital (Q: Dec. 2025 ) + Invested Capital (Q: Mar. 2026 ))/ count )
=-97.72 * ( 1 - 0% )/( (21.406 + 20.25)/ 2 )
=-97.72/20.828
=-469.18 %

where

Note: The Operating Income data used here is four times the quarterly (Mar. 2026) data. The tax rate is limited to between 0% and 100%.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about ROIC % →
What does a ROIC % of -469.18% mean?
Artiva Biotherapeutics (ARTV) has a ROIC % of -469.18% as of Mar. 2026. Return on invested capital is the ratio of current-period net income to average two-period invested capital. View historical data on Artiva Biotherapeutics and its competitors.
Is Artiva Biotherapeutics' ROIC % too high?
Artiva Biotherapeutics' current ROIC % is -469.18%. Overall, Artiva Biotherapeutics has a GF Score™ of 12/100, reflecting its overall financial health beyond just this single metric.
How does Artiva Biotherapeutics' ROIC % compare to ENTA and VNDA?
Artiva Biotherapeutics' ROIC % of -469.18% can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good ROIC % for a Biotechnology company?
A good ROIC % depends on the Biotechnology industry context. However, ROIC % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high ROIC % mean?
A high ROIC % can signal that a stock is expensive relative to its fundamentals. Return on invested capital is the ratio of current-period net income to average two-period invested capital. View historical data on Artiva Biotherapeutics and its competitors. Artiva Biotherapeutics's current ROIC % is -469.18%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Artiva Biotherapeutics stock overvalued right now?
Artiva Biotherapeutics (ARTV) has a current ROIC % of -469.18%. The current ROIC % is -469.18%. Artiva Biotherapeutics' overall GF Score™ is 12/100 with 3 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is ROIC % calculated?
ROIC % is calculated from a company's financial statements. For Artiva Biotherapeutics (ARTV), the current ROIC % is -469.18% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Artiva Biotherapeutics Business Description

Address 5505 Morehouse Drive, Suite 100, San Diego, CA, USA, 92121
Artiva Biotherapeutics Inc is a biopharmaceutical company. The company is engaged in advancing a pipeline of off-the-shelf, allogeneic NK cell therapies for the treatment of hematologic malignancies or solid tumors. The pipeline program of the company includes Artiva-Funded Trials and Collaborator-Funded Trials. The company pipeline includes AlloNK: is an allogeneic, off-the-shelf, cryopreserved NK cell therapy candidate designed to enhance the antibody-dependent cellular cytotoxicity (ADCC) effect of mAbs to drive B-cell. Others products includes: CAR-NK(AB201),CAR-NK(AB205).
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