ARTV (Artiva Biotherapeutics) 3-Year ROIIC % : 140.43% (As of Dec. 2025)

Author: Vera Yuan Vera Yuan
Vera Yuan
Vera Yuan
Director of Data and Quant Analytics at GuruFocus
Focused on building reliable datasets, financial models, and research tools for value-minded investors. Committed to turning complex data into practical guidance for value-investing and long-term wealth.
Reviewed by: Charlie Tian Charlie Tian
Charlie Tian
Charlie Tian
Founder & CEO of GuruFocus
Dr. Charlie Tian is the founder and CEO of GuruFocus.com, a leading global investment research platform established in 2004. With a Ph.D. in physics, Dr. Tian transitioned from science to finance, applying a data-driven, disciplined approach to value investing.

ARTV Artiva Biotherapeutics Inc ARTV
12 GF Score
Price $9.74
! 3 Warning Signs
View Full Analysis

What is Artiva Biotherapeutics 3-Year ROIIC %?

Artiva Biotherapeutics ARTV +8.08% 12 3-Year ROIIC % is 140.43 as of Dec. 2025. GuruFocus rates ARTV with a GF Score™ of 12/100. The stock has 3 warning signs investors should review. Among 1,322 Biotechnology companies, Artiva Biotherapeutics ranks better than 81.09% on this metric.

3-Year Return on Invested Incremental Capital (3-Year ROIIC %) measures the change in earnings as a percentage of change in investment over 3-year. Artiva Biotherapeutics's 3-Year ROIIC % for the quarter that ended in Dec. 2025 was 140.43%. High ROIIC is generally an indication that your business is capital efficient or has a higher operating leverage.

The industry rank for Artiva Biotherapeutics's 3-Year ROIIC % or its related term are showing as below:

ARTV's 3-Year ROIIC % is ranked better than
81.09% of 1322 companies
in the Biotechnology industry
Industry Median: -4.835 vs ARTV: 140.43

Artiva Biotherapeutics  (NAS:ARTV) 3-Year ROIIC % Explanation

Return on Incremental Invested Capital (ROIIC) is an extension of Return on Investment Capital (ROIC). ROIC % tells investors how efficiently that profitability is earned per dollar of company capital. ROIIC narrows the focus even further and shows how profitable each additional unit of capital investment could be. ROIIC % is a more powerful metric than ROIC because it measures how much money the company can generate going forward on future capital investments.

High ROIIC is generally an indication that your business is capital efficient or has a higher operating leverage.

Be Aware

It's important to keep in mind that when tracking ROIIC, the metric is better suited to forecasting the trend of future returns rather than measuring current return on investment.


Artiva Biotherapeutics 3-Year ROIIC % Related Terms


Artiva Biotherapeutics 3-Year ROIIC % Historical Data

* Premium members only.

The historical data trend for Artiva Biotherapeutics's 3-Year ROIIC % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Artiva Biotherapeutics 3-Year ROIIC % Chart

Artiva Biotherapeutics Annual Data
Trend Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
3-Year ROIIC %
Get a 7-Day Free Trial 0.00 0.00 -49.00 -150.27 140.43

Artiva Biotherapeutics Quarterly Data
Dec19 Dec20 Mar21 Sep21 Dec21 Mar22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
3-Year ROIIC % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 0.00 0.00 0.00 140.43 0.00

ARTV vs OVID, INDP, CCCC: 3-Year ROIIC % Comparison

For the Biotechnology subindustry, Artiva Biotherapeutics's 3-Year ROIIC %, along with its competitors' market caps and 3-Year ROIIC % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Artiva Biotherapeutics 3-Year ROIIC % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Artiva Biotherapeutics's 3-Year ROIIC % distribution charts can be found below:

* The bar in red indicates where Artiva Biotherapeutics's 3-Year ROIIC % falls into.


ARTV
12GF Score
Artiva Biotherapeutics Inc ARTV
3-Year ROIIC % is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

Artiva Biotherapeutics 3-Year ROIIC % Calculation

Artiva Biotherapeutics's 3-Year ROIIC % for the quarter that ended in Dec. 2025 is calculated as:

3-Year ROIIC %=3-Year Incremental Net Operating Profit After Taxes (NOPAT)**/3-Year Incremental Invested Capital**
=( -89.81 (Dec. 2025) - -59.829 (Dec. 2022) )/( 21.406 (Dec. 2025) - 42.756 (Dec. 2022) )
=-29.981/-21.35
=140.43%***

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

** Annual data of NOPAT and Invested Capital was used to calculate 3-Year ROIIC %.
*** Please be aware that the ROIIC (Return on Invested Capital) calculations are based on company-level data using the primary share class. The calculated data provided is for demonstration purposes and may slightly differ from the results displayed in the title due to potential variations caused by currency exchange rate differences throughout the year.

Frequently Asked Questions Learn more about 3-Year ROIIC % →
What does a 3-Year ROIIC % of 140.43 mean?
Artiva Biotherapeutics (ARTV) has a 3-Year ROIIC % of 140.43 as of Dec. 2025. 3-Year ROIIC % measures the change in earnings as a percentage of change in investment over 3-year. View historical data on Artiva Biotherapeutics and its competitors. According to the industry distribution chart, Artiva Biotherapeutics ranks #250 out of 1322 companies in the Biotechnology industry, placing it in the top 18.9%.
Is Artiva Biotherapeutics' 3-Year ROIIC % too high?
Artiva Biotherapeutics' current 3-Year ROIIC % is 140.43. Based on the distribution chart, Artiva Biotherapeutics ranks #250 out of 1322 companies in the Biotechnology industry, which is in the top quartile — a strong position relative to peers. Overall, Artiva Biotherapeutics has a GF Score™ of 12/100, reflecting its overall financial health beyond just this single metric.
How does Artiva Biotherapeutics' 3-Year ROIIC % compare to OVID and INDP?
According to the Biotechnology industry distribution chart, Artiva Biotherapeutics ranks #250 out of 1322 companies for 3-Year ROIIC %. This places Artiva Biotherapeutics in the top 19% of its industry — outperforming the majority of peers. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good 3-Year ROIIC % for a Biotechnology company?
A good 3-Year ROIIC % depends on the Biotechnology industry context. However, 3-Year ROIIC % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high 3-Year ROIIC % mean?
A high 3-Year ROIIC % can signal that a stock is expensive relative to its fundamentals. 3-Year ROIIC % measures the change in earnings as a percentage of change in investment over 3-year. View historical data on Artiva Biotherapeutics and its competitors. Artiva Biotherapeutics's current 3-Year ROIIC % is 140.43. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Artiva Biotherapeutics stock overvalued right now?
Artiva Biotherapeutics (ARTV) has a current 3-Year ROIIC % of 140.43. The current 3-Year ROIIC % is 140.43. Artiva Biotherapeutics' overall GF Score™ is 12/100 with 3 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is 3-Year ROIIC % calculated?
3-Year ROIIC % is calculated from a company's financial statements. For Artiva Biotherapeutics (ARTV), the current 3-Year ROIIC % is 140.43 as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Artiva Biotherapeutics Business Description

Address 5505 Morehouse Drive, Suite 100, San Diego, CA, USA, 92121
Artiva Biotherapeutics Inc is a biopharmaceutical company. The company is engaged in advancing a pipeline of off-the-shelf, allogeneic NK cell therapies for the treatment of hematologic malignancies or solid tumors. The pipeline program of the company includes Artiva-Funded Trials and Collaborator-Funded Trials. The company pipeline includes AlloNK: is an allogeneic, off-the-shelf, cryopreserved NK cell therapy candidate designed to enhance the antibody-dependent cellular cytotoxicity (ADCC) effect of mAbs to drive B-cell. Others products includes: CAR-NK(AB201),CAR-NK(AB205).
12GF Score

Get the complete analysis for ARTV

3-Year ROIIC % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$9.74
Price