HSITF (Hadasit Bio Holdings) ROIC %: -254.93% (As of Dec. 2025)


HSITF Hadasit Bio Holdings Ltd HSITF
14 GF Score
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What is Hadasit Bio Holdings ROIC %?

Hadasit Bio Holdings HSITF 14 ROIC % is -254.93% as of Dec. 2025. GuruFocus rates HSITF with a GF Score™ of 14/100. The stock has 3 warning signs investors should review.

ROIC % measures how well a company generates cash flow relative to the capital it has invested in its business. It is also called ROC %. Hadasit Bio Holdings's annualized return on invested capital (ROIC %) for the quarter that ended in Dec. 2025 was -254.93%.

As of today (2026-06-26), Hadasit Bio Holdings's WACC % is 3.39%. Hadasit Bio Holdings's ROIC % is -321.19% (calculated using TTM income statement data). Hadasit Bio Holdings earns returns that do not match up to its cost of capital. It will destroy value as it grows.


Hadasit Bio Holdings  (OTCPK:HSITF) ROIC % Explanation

ROIC % measures how well a company generates cash flow relative to the capital it has invested in its business. It is also called ROC %. The reason book values of debt and equity are used is because the book values are the capital the company received when issuing the debt or receiving the equity investments.

There are four key components to this definition. The first is the use of operating income or EBIT rather than net income in the numerator. The second is the tax adjustment to this operating income or EBIT, computed as a hypothetical tax based on an effective or marginal tax rate. The third is the use of book values for invested capital, rather than market values. The final is the timing difference; the capital invested is from the end of the prior year whereas the operating income or EBIT is the current year's number.

Why is ROIC % important?

Because it costs money to raise capital. A firm that generates higher returns on investment than it costs the company to raise the capital needed for that investment is earning excess returns. A firm that expects to continue generating positive excess returns on new investments in the future will see its value increase as growth increases, whereas a firm that earns returns that do not match up to its cost of capital will destroy value as it grows.

As of today, Hadasit Bio Holdings's WACC % is 3.39%. Hadasit Bio Holdings's ROIC % is -321.19% (calculated using TTM income statement data). Hadasit Bio Holdings earns returns that do not match up to its cost of capital. It will destroy value as it grows.


Be Aware

Like ROE % and ROA %, ROIC % is calculated with only 12 months of data. Fluctuations in the company's earnings or business cycles can affect the ratio drastically. It is important to look at the ratio from a long term perspective.


Hadasit Bio Holdings ROIC % Related Terms


Hadasit Bio Holdings ROIC % Historical Data

* Premium members only.

The historical data trend for Hadasit Bio Holdings's ROIC % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Hadasit Bio Holdings ROIC % Chart

Hadasit Bio Holdings Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
ROIC %
Get a 7-Day Free Trial Premium Member Only Premium Member Only -8.72 -8.02 -13.38 -159.71 -262.00

Hadasit Bio Holdings Semi-Annual Data
Jun16 Dec16 Jun17 Dec17 Jun18 Dec18 Jun19 Dec19 Jun20 Dec20 Jun21 Dec21 Jun22 Dec22 Jun23 Dec23 Jun24 Dec24 Jun25 Dec25
ROIC % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -49.44 -65.58 -164.22 -697.29 -254.93

HSITF vs VRTX, REGN, ALNY: ROIC % Comparison

For the Biotechnology subindustry, Hadasit Bio Holdings's ROIC %, along with its competitors' market caps and ROIC % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Hadasit Bio Holdings ROIC % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Hadasit Bio Holdings's ROIC % distribution charts can be found below:

* The bar in red indicates where Hadasit Bio Holdings's ROIC % falls into.


HSITF
14GF Score
Hadasit Bio Holdings Ltd HSITF
ROIC % is just one metric. See GF Score™, valuation, warning signs, and more.
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Hadasit Bio Holdings ROIC % Calculation

Hadasit Bio Holdings's annualized Return on Invested Capital (ROIC %) for the fiscal year that ended in Dec. 2025 is calculated as:

ROIC % (A: Dec. 2025 )
=NOPAT/Average Invested Capital
=Operating Income * ( 1 - Tax Rate % )/( (Invested Capital (A: Dec. 2024 ) + Invested Capital (A: Dec. 2025 ))/ count )
=-0.562 * ( 1 - 0% )/( (0.048 + 0.381)/ 2 )
=-0.562/0.2145
=-262.00 %

where

Hadasit Bio Holdings's annualized Return on Invested Capital (ROIC %) for the quarter that ended in Dec. 2025 is calculated as:

ROIC % (Q: Dec. 2025 )
=NOPAT/Average Invested Capital
=Operating Income * ( 1 - Tax Rate % )/( (Invested Capital (Q: Jun. 2025 ) + Invested Capital (Q: Dec. 2025 ))/ count )
=-0.608 * ( 1 - 0% )/( (0.096 + 0.381)/ 2 )
=-0.608/0.2385
=-254.93 %

where

Note: The Operating Income data used here is two times the semi-annual (Dec. 2025) data. The tax rate is limited to between 0% and 100%.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about ROIC % →
What does a ROIC % of -254.93% mean?
Hadasit Bio Holdings (HSITF) has a ROIC % of -254.93% as of Dec. 2025. Return on invested capital is the ratio of current-period net income to average two-period invested capital. View historical data on Hadasit Bio Holdings and its competitors.
Is Hadasit Bio Holdings' ROIC % too high?
Hadasit Bio Holdings' current ROIC % is -254.93%. Overall, Hadasit Bio Holdings has a GF Score™ of 14/100, reflecting its overall financial health beyond just this single metric.
How does Hadasit Bio Holdings' ROIC % compare to VRTX and REGN?
Hadasit Bio Holdings' ROIC % of -254.93% can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good ROIC % for a Biotechnology company?
A good ROIC % depends on the Biotechnology industry context. However, ROIC % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high ROIC % mean?
A high ROIC % can signal that a stock is expensive relative to its fundamentals. Return on invested capital is the ratio of current-period net income to average two-period invested capital. View historical data on Hadasit Bio Holdings and its competitors. Hadasit Bio Holdings's current ROIC % is -254.93%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Hadasit Bio Holdings stock overvalued right now?
Hadasit Bio Holdings (HSITF) has a current ROIC % of -254.93%. The current ROIC % is -254.93%. Hadasit Bio Holdings' overall GF Score™ is 14/100 with 3 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is ROIC % calculated?
ROIC % is calculated from a company's financial statements. For Hadasit Bio Holdings (HSITF), the current ROIC % is -254.93% as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Hadasit Bio Holdings Business Description

Other Exchanges HDST-M:Israel
Address 5th Floor, Jerusaelm Bio-Park, Hadassah Ein-Kerem Campus, Jerusalem, ISR, 91120
Hadasit Bio Holdings Ltd serves as a precedent in the field of biotech financing. It is engaged in the advancement and enhancement of its portfolio companies. Its portfolio companies are involved in the field of medical and biotechnological research and production and distribution of the results of the research and development done in these areas.
14GF Score

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ROIC % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

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