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10-Year Return on Invested Incremental Capital (10-Year ROIIC %) measures the change in earnings as a percentage of change in investment over 10-year.
Inovio Pharmaceuticals's 10-Year ROIIC % for the quarter that ended in Dec. 2025 was 577.37%. High ROIIC is generally an indication that your business is capital efficient or has a higher operating leverage.
The industry rank for Inovio Pharmaceuticals's 10-Year ROIIC % or its related term are showing as below:
MEX:INO's 10-Year ROIIC % is ranked better than 94.57% of 1105
companies
in the Biotechnology industry
Industry Median: -19.8
vs MEX:INO: 577.37
Return on Incremental Invested Capital (ROIIC) is an extension of Return on Investment Capital (ROIC). ROIC % tells investors how efficiently that profitability is earned per dollar of company capital. ROIIC narrows the focus even further and shows how profitable each additional unit of capital investment could be. ROIIC % is a more powerful metric than ROIC because it measures how much money the company can generate going forward on future capital investments.
High ROIIC is generally an indication that your business is capital efficient or has a higher operating leverage.
Be Aware
It's important to keep in mind that when tracking ROIIC, the metric is better suited to forecasting the trend of future returns rather than measuring current return on investment.
Inovio Pharmaceuticals 10-Year ROIIC % Related Terms
Inovio Pharmaceuticals 10-Year ROIIC % Historical Data
* Premium members only.
The historical data trend for Inovio Pharmaceuticals's 10-Year ROIIC % can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
MEX:INO vs TELO, ELTX, ALPS: 10-Year ROIIC % Comparison
For the Biotechnology subindustry, Inovio Pharmaceuticals's 10-Year ROIIC %, along with its competitors' market caps and 10-Year ROIIC % data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
Inovio Pharmaceuticals 10-Year ROIIC % vs Biotechnology Industry
For the Biotechnology industry and Healthcare sector, Inovio Pharmaceuticals's 10-Year ROIIC % distribution charts can be found below:
* The bar in red indicates where Inovio Pharmaceuticals's 10-Year ROIIC % falls into.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
** Annual data of NOPAT and Invested Capital was used to calculate 10-Year ROIIC %.
*** Please be aware that the ROIIC (Return on Invested Capital) calculations are based on company-level data using the primary share class. The calculated data provided is for demonstration purposes and may slightly differ from the results displayed in the title due to potential variations caused by currency exchange rate differences throughout the year.
Inovio Pharmaceuticals (MEX:INO) has a 10-Year ROIIC % of 577.37 as of Dec. 2025. 10-Year ROIIC % measures the change in earnings as a percentage of change in investment over 10-year. View historical data on Inovio Pharmaceuticals and its competitors. According to the industry distribution chart, Inovio Pharmaceuticals ranks #60 out of 1105 companies in the Biotechnology industry, placing it in the top 5.4%.
Is Inovio Pharmaceuticals' 10-Year ROIIC % too high?
Inovio Pharmaceuticals' current 10-Year ROIIC % is 577.37. Based on the distribution chart, Inovio Pharmaceuticals ranks #60 out of 1105 companies in the Biotechnology industry, which is in the top quartile — a strong position relative to peers. Overall, Inovio Pharmaceuticals has a GF Score™ of 40/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Inovio Pharmaceuticals' 10-Year ROIIC % compare to TELO and ELTX?
According to the Biotechnology industry distribution chart, Inovio Pharmaceuticals ranks #60 out of 1105 companies for 10-Year ROIIC %. This places Inovio Pharmaceuticals in the top 5% of its industry — outperforming the majority of peers. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good 10-Year ROIIC % for a Biotechnology company?
A good 10-Year ROIIC % depends on the Biotechnology industry context. However, 10-Year ROIIC % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high 10-Year ROIIC % mean?
A high 10-Year ROIIC % can signal that a stock is expensive relative to its fundamentals. 10-Year ROIIC % measures the change in earnings as a percentage of change in investment over 10-year. View historical data on Inovio Pharmaceuticals and its competitors. Inovio Pharmaceuticals's current 10-Year ROIIC % is 577.37. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Inovio Pharmaceuticals stock overvalued right now?
Based on GuruFocus' analysis, Inovio Pharmaceuticals (MEX:INO) is currently considered Significantly Overvalued. The stock's GF Value™ is MXN3.68, compared to a current price of MXN11.50 — trading 212.5% above its estimated fair value. The current 10-Year ROIIC % is 577.37. Inovio Pharmaceuticals' overall GF Score™ is 40/100 with 4 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is 10-Year ROIIC % calculated?
10-Year ROIIC % is calculated from a company's financial statements. For Inovio Pharmaceuticals (MEX:INO), the current 10-Year ROIIC % is 577.37 as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Is Inovio Pharmaceuticals (MEX:INO) Overvalued in 2026?
Based on GuruFocus' analysis, Inovio Pharmaceuticals stock appears to be overvalued.
The current stock price of MXN11.50 is trading 212.5% above its estimated GF Value™ of MXN3.68.
GuruFocus considers Inovio Pharmaceuticals to be Significantly Overvalued.
Key valuation signals for MEX:INO:
10-Year ROIIC %: 577.37
GF Value™: MXN3.68 vs. price of MXN11.50 (212.5% above fair value)
No single metric tells the full story. See the MEX:INO stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.
Inovio Pharmaceuticals Inc is a clinical-stage biotechnology company focused on developing and commercializing DNA medicines to help treat and protect people from diseases associated with human papillomavirus (HPV), cancer and infectious diseases. INOVIO's platform harnesses the power of in vivo protein production, featuring optimized design and delivery of DNA medicines that teach the body to manufacture its own disease-fighting tools. Its candidate is INO-3107 for the treatment of recurrent respiratory papillomatosis (RRP), a chronic, rare and debilitating disease of the respiratory tract caused by HPV infection. In its completed Phase 1/2 clinical trial of INO-3107 for the treatment of HPV-6 and HPV-11-associated RRP.
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