PPTDF (PeptiDream) 10-Year ROIIC % : -8.03% (As of Dec. 2025)


PPTDF PeptiDream Inc PPTDF
76 GF Score
Price $6.00
GF Value $10.31
Valuation Possible Value Trap
! 4 Warning Signs
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What is PeptiDream 10-Year ROIIC %?

PeptiDream PPTDF 76 10-Year ROIIC % is -8.03 as of Dec. 2025. GuruFocus rates PPTDF with a GF Score™ of 76/100 and a GF Value™ of $10.31 (Possible Value Trap). The stock has 4 warning signs investors should review. Among 1,104 Biotechnology companies, PeptiDream ranks better than 56.07% on this metric.

10-Year Return on Invested Incremental Capital (10-Year ROIIC %) measures the change in earnings as a percentage of change in investment over 10-year. PeptiDream's 10-Year ROIIC % for the quarter that ended in Dec. 2025 was -8.03%. High ROIIC is generally an indication that your business is capital efficient or has a higher operating leverage.

The industry rank for PeptiDream's 10-Year ROIIC % or its related term are showing as below:

PPTDF's 10-Year ROIIC % is ranked better than
56.07% of 1104 companies
in the Biotechnology industry
Industry Median: -19.8 vs PPTDF: -8.03

PeptiDream  (OTCPK:PPTDF) 10-Year ROIIC % Explanation

Return on Incremental Invested Capital (ROIIC) is an extension of Return on Investment Capital (ROIC). ROIC % tells investors how efficiently that profitability is earned per dollar of company capital. ROIIC narrows the focus even further and shows how profitable each additional unit of capital investment could be. ROIIC % is a more powerful metric than ROIC because it measures how much money the company can generate going forward on future capital investments.

High ROIIC is generally an indication that your business is capital efficient or has a higher operating leverage.

Be Aware

It's important to keep in mind that when tracking ROIIC, the metric is better suited to forecasting the trend of future returns rather than measuring current return on investment.


PeptiDream 10-Year ROIIC % Related Terms


PeptiDream 10-Year ROIIC % Historical Data

* Premium members only.

The historical data trend for PeptiDream's 10-Year ROIIC % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

PeptiDream 10-Year ROIIC % Chart

PeptiDream Annual Data
Trend Jun16 Jun17 Jun18 Jun19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
10-Year ROIIC %
Get a 7-Day Free Trial Premium Member Only Premium Member Only 0.00 0.00 9.91 37.38 -8.03

PeptiDream Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
10-Year ROIIC % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 0.00 0.00 0.00 -8.03 0.00

PPTDF vs VRTX, REGN, ALNY: 10-Year ROIIC % Comparison

For the Biotechnology subindustry, PeptiDream's 10-Year ROIIC %, along with its competitors' market caps and 10-Year ROIIC % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


PeptiDream 10-Year ROIIC % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, PeptiDream's 10-Year ROIIC % distribution charts can be found below:

* The bar in red indicates where PeptiDream's 10-Year ROIIC % falls into.


PPTDF
76GF Score
PeptiDream Inc PPTDF
10-Year ROIIC % is just one metric. See GF Score™, valuation, warning signs, and more.
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PeptiDream 10-Year ROIIC % Calculation

PeptiDream's 10-Year ROIIC % for the quarter that ended in Dec. 2025 is calculated as:

10-Year ROIIC %=10-Year Incremental Net Operating Profit After Taxes (NOPAT)**/10-Year Incremental Invested Capital**
=( -22.6935874 (Dec. 2025) - 7.5604656 (Jun. 2015) )/( 367.371 (Dec. 2025) - 12.732 (Jun. 2015) )
=-30.254053/354.639
=-8.53%***

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

** Annual data of NOPAT and Invested Capital was used to calculate 10-Year ROIIC %.
*** Please be aware that the ROIIC (Return on Invested Capital) calculations are based on company-level data using the primary share class. The calculated data provided is for demonstration purposes and may slightly differ from the results displayed in the title due to potential variations caused by currency exchange rate differences throughout the year.

Frequently Asked Questions Learn more about 10-Year ROIIC % →
What does a 10-Year ROIIC % of -8.03 mean?
PeptiDream (PPTDF) has a 10-Year ROIIC % of -8.03 as of Dec. 2025. 10-Year ROIIC % measures the change in earnings as a percentage of change in investment over 10-year. View historical data on PeptiDream and its competitors. According to the industry distribution chart, PeptiDream ranks #485 out of 1104 companies in the Biotechnology industry, placing it in the top 43.9%.
Is PeptiDream's 10-Year ROIIC % too high?
PeptiDream's current 10-Year ROIIC % is -8.03. Based on the distribution chart, PeptiDream ranks #485 out of 1104 companies in the Biotechnology industry, which is above the industry midpoint. Overall, PeptiDream has a GF Score™ of 76/100 and is considered Possible Value Trap, reflecting its overall financial health beyond just this single metric.
How does PeptiDream's 10-Year ROIIC % compare to VRTX and REGN?
According to the Biotechnology industry distribution chart, PeptiDream ranks #485 out of 1104 companies for 10-Year ROIIC %. This puts PeptiDream in the upper half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good 10-Year ROIIC % for a Biotechnology company?
A good 10-Year ROIIC % depends on the Biotechnology industry context. However, 10-Year ROIIC % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high 10-Year ROIIC % mean?
A high 10-Year ROIIC % can signal that a stock is expensive relative to its fundamentals. 10-Year ROIIC % measures the change in earnings as a percentage of change in investment over 10-year. View historical data on PeptiDream and its competitors. PeptiDream's current 10-Year ROIIC % is -8.03. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is PeptiDream stock overvalued right now?
Based on GuruFocus' analysis, PeptiDream (PPTDF) is currently considered Possible Value Trap. The stock's GF Value™ is $10.31, compared to a current price of $6.00 — trading 41.8% below its estimated fair value. The current 10-Year ROIIC % is -8.03. PeptiDream's overall GF Score™ is 76/100 with 4 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is 10-Year ROIIC % calculated?
10-Year ROIIC % is calculated from a company's financial statements. For PeptiDream (PPTDF), the current 10-Year ROIIC % is -8.03 as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is PeptiDream (PPTDF) Overvalued in 2026?

Based on GuruFocus' analysis, PeptiDream stock appears to be undervalued. The current stock price of $6.00 is trading 41.8% below its estimated GF Value™ of $10.31. GuruFocus considers PeptiDream to be Possible Value Trap.

Key valuation signals for PPTDF:

  • 10-Year ROIIC %: -8.03
  • GF Value™: $10.31 vs. price of $6.00 (41.8% below fair value)
  • GF Score™: 76/100 with 4 warning signs

No single metric tells the full story. See the PPTDF stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


PeptiDream Business Description

Other Exchanges 4587:Japan
Address 3-25-23 Tonomachi, Kawasaki-ku, Kanagawa Prefecture, Kawasaki, JPN, 210-0821
PeptiDream Inc is engaged in the drug discovery and development business. The group utilizes PDPS, its proprietary drug discovery and development platform system, for drug discovery and development, and it conducts radiopharmaceutical business through a wholly owned subsidiary and is involved in the research, development, and manufacturing of pharmaceuticals, etc. Its reportable segments are Drug discovery and development business and Radiopharmaceutical business.
76GF Score

Get the complete analysis for PPTDF

10-Year ROIIC % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$6.00
Price
$10.31
GF Value