PPTDF (PeptiDream) EV-to-EBITDA: -42.97 (As of Jul. 18, 2026)

Author: Vera Yuan Vera Yuan
Vera Yuan
Vera Yuan
Director of Data and Quant Analytics at GuruFocus
Focused on building reliable datasets, financial models, and research tools for value-minded investors. Committed to turning complex data into practical guidance for value-investing and long-term wealth.
Reviewed by: Charlie Tian Charlie Tian
Charlie Tian
Charlie Tian
Founder & CEO of GuruFocus
Dr. Charlie Tian is the founder and CEO of GuruFocus.com, a leading global investment research platform established in 2004. With a Ph.D. in physics, Dr. Tian transitioned from science to finance, applying a data-driven, disciplined approach to value investing.

PPTDF PeptiDream Inc PPTDF
76 GF Score
Price $5.99
GF Value $10.57
Valuation Possible Value Trap
! 4 Warning Signs
View Full Analysis

What is PeptiDream EV-to-EBITDA?

PeptiDream PPTDF 76 EV-to-EBITDA is -42.97 as of Jul. 18, 2026. GuruFocus rates PPTDF with a GF Score™ of 76/100 and a GF Value™ of $10.57 (Possible Value Trap). The stock has 4 warning signs investors should review. Among 398 Biotechnology companies, PeptiDream ranks worse than 251256.03% on this metric.

EV-to-EBITDA is calculated as enterprise value divided by its EBITDA. As of today, PeptiDream's enterprise value is $717.3 Mil. PeptiDream's EBITDA for the trailing twelve months (TTM) ended in Mar. 2026 was $-16.7 Mil. Therefore, PeptiDream's EV-to-EBITDA for today is -42.97.

The historical rank and industry rank for PeptiDream's EV-to-EBITDA or its related term are showing as below:

PPTDF' s EV-to-EBITDA Range Over the Past 10 Years
Min: -81.52   Med: 96.24   Max: 719.18
Current: -46.32

During the past 13 years, the highest EV-to-EBITDA of PeptiDream was 719.18. The lowest was -81.52. And the median was 96.24.

PPTDF's EV-to-EBITDA is ranked worse than
100% of 398 companies
in the Biotechnology industry
Industry Median: 12.29 vs PPTDF: -46.32

EV-to-EBITDA is a valuation multiple used in finance and investment to measure the value of a company. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio to determine the fair market value of a company.

As of today (2026-07-18), PeptiDream's stock price is $5.992. PeptiDream's Earnings per Share (Diluted) for the trailing twelve months (TTM) ended in Mar. 2026 was $-0.183. Therefore, PeptiDream's PE Ratio (TTM) for today is At Loss.

The "classic" EV-to-EBITDA is much better in capturing debt and net cash than the PE Ratio (TTM).


PeptiDream  (OTCPK:PPTDF) EV-to-EBITDA Explanation

EV-to-EBITDA is a valuation multiple used in finance and investment to measure the value of a company. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio (TTM) to determine the fair market value of a company.

PeptiDream's PE Ratio (TTM) for today is calculated as:

PE Ratio (TTM)=Share Price (Today)/Earnings per Share (Diluted) (TTM)
=5.992/-0.183
=At Loss

PeptiDream's share price for today is $5.992.
PeptiDream's Earnings per Share (Diluted) for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-0.183.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Study has found that the companies with the lowest EV-to-EBITDA outperforms companies measured as cheap by other ratios such as PE Ratio (TTM).

Please read Which price ratio outperforms the enterprise multiple?


PeptiDream EV-to-EBITDA Related Terms


PeptiDream EV-to-EBITDA Historical Data

* Premium members only.

The historical data trend for PeptiDream's EV-to-EBITDA can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

PeptiDream EV-to-EBITDA Chart

PeptiDream Annual Data
Trend Jun16 Jun17 Jun18 Jun19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
EV-to-EBITDA
Get a 7-Day Free Trial Premium Member Only Premium Member Only 71.81 26.09 21.61 13.21 -75.37

PeptiDream Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
EV-to-EBITDA Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 11.30 -54.03 -38.08 -75.37 -57.73

PPTDF vs VRTX, REGN, ALNY: EV-to-EBITDA Comparison

For the Biotechnology subindustry, PeptiDream's EV-to-EBITDA, along with its competitors' market caps and EV-to-EBITDA data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


PeptiDream EV-to-EBITDA vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, PeptiDream's EV-to-EBITDA distribution charts can be found below:

* The bar in red indicates where PeptiDream's EV-to-EBITDA falls into.


PPTDF
76GF Score
PeptiDream Inc PPTDF
EV-to-EBITDA is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

PeptiDream EV-to-EBITDA Calculation

PeptiDream's EV-to-EBITDA for today is calculated as:

EV-to-EBITDA=Enterprise Value (Today)/EBITDA (TTM)
=717.340/-16.695
=-42.97

PeptiDream's current Enterprise Value is $717.3 Mil.
PeptiDream's EBITDA for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-16.7 Mil.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about EV-to-EBITDA →
What does a EV-to-EBITDA of -42.97 mean?
PeptiDream (PPTDF) has a EV-to-EBITDA of -42.97 as of Jul. 18, 2026. EV to EBITDA ratio is the company's enterprise value divided by earnings before interest, taxes, depreciation and amortization. View historical data on PeptiDream. According to the industry distribution chart, PeptiDream ranks #999999 out of 398 companies in the Biotechnology industry.
Is PeptiDream's EV-to-EBITDA too high?
PeptiDream's current EV-to-EBITDA is -42.97. Based on the distribution chart, PeptiDream ranks #999999 out of 398 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, PeptiDream has a GF Score™ of 76/100 and is considered Possible Value Trap, reflecting its overall financial health beyond just this single metric.
How does PeptiDream's EV-to-EBITDA compare to VRTX and REGN?
According to the Biotechnology industry distribution chart, PeptiDream ranks #999999 out of 398 companies for EV-to-EBITDA. This places PeptiDream in the lower half of its industry. The industry median EV-to-EBITDA is 12.29. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good EV-to-EBITDA for a Biotechnology company?
The median EV-to-EBITDA among Biotechnology companies is 12.29, based on 398 companies in the industry. Companies in the top quartile (top 25%) have a EV-to-EBITDA significantly above this median, while those in the bottom quartile fall well below. However, EV-to-EBITDA should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high EV-to-EBITDA mean?
A high EV-to-EBITDA can signal that a stock is expensive relative to its fundamentals. EV to EBITDA ratio is the company's enterprise value divided by earnings before interest, taxes, depreciation and amortization. View historical data on PeptiDream. For the Biotechnology industry, the median EV-to-EBITDA is 12.29 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. PeptiDream's current EV-to-EBITDA is -42.97. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is PeptiDream stock overvalued right now?
Based on GuruFocus' analysis, PeptiDream (PPTDF) is currently considered Possible Value Trap. The stock's GF Value™ is $10.57, compared to a current price of $5.99 — trading 43.3% below its estimated fair value. The current EV-to-EBITDA is -42.97. PeptiDream's overall GF Score™ is 76/100 with 4 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is EV-to-EBITDA calculated?
EV-to-EBITDA is calculated from a company's financial statements. For PeptiDream (PPTDF), the current EV-to-EBITDA is -42.97 as of Jul. 18, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is PeptiDream (PPTDF) Overvalued in 2026?

Based on GuruFocus' analysis, PeptiDream stock appears to be undervalued. The current stock price of $5.99 is trading 43.3% below its estimated GF Value™ of $10.57. GuruFocus considers PeptiDream to be Possible Value Trap.

Key valuation signals for PPTDF:

  • EV-to-EBITDA: -42.97
  • GF Value™: $10.57 vs. price of $5.99 (43.3% below fair value)
  • GF Score™: 76/100 with 4 warning signs

No single metric tells the full story. See the PPTDF stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


PeptiDream Business Description

Other Exchanges 4587:Japan
Address 3-25-23 Tonomachi, Kawasaki-ku, Kanagawa Prefecture, Kawasaki, JPN, 210-0821
PeptiDream Inc is engaged in the drug discovery and development business. The group utilizes PDPS, its proprietary drug discovery and development platform system, for drug discovery and development, and it conducts radiopharmaceutical business through a wholly owned subsidiary and is involved in the research, development, and manufacturing of pharmaceuticals, etc. Its reportable segments are Drug discovery and development business and Radiopharmaceutical business.
76GF Score

Get the complete analysis for PPTDF

EV-to-EBITDA is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$5.99
Price
$10.57
GF Value