Sanofi (XSWX:SAN) 1-Year ROIIC % : -424.14% (As of Dec. 2025)


XSWX:SAN Sanofi SA XSWX:SAN
87 GF Score
Price CHF73.20
GF Value CHF104.30
! 2 Warning Signs
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What is Sanofi 1-Year ROIIC %?

Sanofi XSWX:SAN 87 1-Year ROIIC % is -424.14 as of Dec. 2025. GuruFocus rates XSWX:SAN with a GF Score™ of 87/100 and a GF Value™ of CHF104.30. The stock has 2 warning signs investors should review. Among 968 Drug Manufacturers companies, Sanofi ranks worse than 96.28% on this metric.

1-Year Return on Invested Incremental Capital (1-Year ROIIC %) measures the change in earnings as a percentage of change in investment over 1-year. Sanofi's 1-Year ROIIC % for the quarter that ended in Dec. 2025 was -424.14%. High ROIIC is generally an indication that your business is capital efficient or has a higher operating leverage.

The industry rank for Sanofi's 1-Year ROIIC % or its related term are showing as below:

XSWX:SAN's 1-Year ROIIC % is ranked worse than
96.28% of 968 companies
in the Drug Manufacturers industry
Industry Median: 1.315 vs XSWX:SAN: -424.14

Sanofi  (XSWX:SAN) 1-Year ROIIC % Explanation

Return on Incremental Invested Capital (ROIIC) is an extension of Return on Investment Capital (ROIC). ROIC % tells investors how efficiently that profitability is earned per dollar of company capital. ROIIC narrows the focus even further and shows how profitable each additional unit of capital investment could be. ROIIC % is a more powerful metric than ROIC because it measures how much money the company can generate going forward on future capital investments.

High ROIIC is generally an indication that your business is capital efficient or has a higher operating leverage.

Be Aware

It's important to keep in mind that when tracking ROIIC, the metric is better suited to forecasting the trend of future returns rather than measuring current return on investment.


Sanofi 1-Year ROIIC % Related Terms


Sanofi 1-Year ROIIC % Historical Data

* Premium members only.

The historical data trend for Sanofi's 1-Year ROIIC % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Sanofi 1-Year ROIIC % Chart

Sanofi Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
1-Year ROIIC %
Get a 7-Day Free Trial Premium Member Only Premium Member Only 0.00 32.37 -58.04 0.91 -424.14

Sanofi Semi-Annual Data
Jun16 Dec16 Jun17 Dec17 Jun18 Dec18 Jun19 Dec19 Jun20 Dec20 Jun21 Dec21 Jun22 Dec22 Jun23 Dec23 Jun24 Dec24 Jun25 Dec25
1-Year ROIIC % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -58.04 -21.36 0.91 -10.32 -424.14

XSWX:SAN vs LLY, JNJ, ABBV: 1-Year ROIIC % Comparison

For the Drug Manufacturers - General subindustry, Sanofi's 1-Year ROIIC %, along with its competitors' market caps and 1-Year ROIIC % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Sanofi 1-Year ROIIC % vs Drug Manufacturers Industry

For the Drug Manufacturers industry and Healthcare sector, Sanofi's 1-Year ROIIC % distribution charts can be found below:

* The bar in red indicates where Sanofi's 1-Year ROIIC % falls into.


XSWX:SAN
87GF Score
Sanofi SA XSWX:SAN
1-Year ROIIC % is just one metric. See GF Score™, valuation, warning signs, and more.
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Sanofi 1-Year ROIIC % Calculation

Sanofi's 1-Year ROIIC % for the quarter that ended in Dec. 2025 is calculated as:

1-Year ROIIC %=1-Year Incremental Net Operating Profit After Taxes (NOPAT)**/1-Year Incremental Invested Capital
=( 7442.7722697 (Dec. 2025) - 6832.778625 (Dec. 2024) )/( 107453.66 (Dec. 2025) - 107652.997 (Dec. 2024) )
=609.9936447/-199.33699999998
=-306.01%***

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

** TTM data of NOPAT and Invested Capital was used to calculate 1-Year ROIIC %.
*** Please be aware that the ROIIC (Return on Invested Capital) calculations are based on company-level data using the primary share class. The calculated data provided is for demonstration purposes and may slightly differ from the results displayed in the title due to potential variations caused by currency exchange rate differences throughout the year.

Frequently Asked Questions Learn more about 1-Year ROIIC % →
What does a 1-Year ROIIC % of -424.14 mean?
Sanofi (XSWX:SAN) has a 1-Year ROIIC % of -424.14 as of Dec. 2025. 1-Year ROIIC % measures the change in earnings as a percentage of change in investment over 1-year. View historical data on Sanofi and its competitors. According to the industry distribution chart, Sanofi ranks #932 out of 968 companies in the Drug Manufacturers industry, placing it in the top 96.3%.
Is Sanofi's 1-Year ROIIC % too high?
Sanofi's current 1-Year ROIIC % is -424.14. Based on the distribution chart, Sanofi ranks #932 out of 968 companies in the Drug Manufacturers industry, which is in the bottom quartile relative to peers. Overall, Sanofi has a GF Score™ of 87/100, reflecting its overall financial health beyond just this single metric.
How does Sanofi's 1-Year ROIIC % compare to LLY and JNJ?
According to the Drug Manufacturers industry distribution chart, Sanofi ranks #932 out of 968 companies for 1-Year ROIIC %. This places Sanofi in the lower half of its industry. The industry median 1-Year ROIIC % is 1.32. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good 1-Year ROIIC % for a Drug Manufacturers company?
The median 1-Year ROIIC % among Drug Manufacturers companies is 1.32, based on 968 companies in the industry. Companies in the top quartile (top 25%) have a 1-Year ROIIC % significantly above this median, while those in the bottom quartile fall well below. However, 1-Year ROIIC % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high 1-Year ROIIC % mean?
A high 1-Year ROIIC % can signal that a stock is expensive relative to its fundamentals. 1-Year ROIIC % measures the change in earnings as a percentage of change in investment over 1-year. View historical data on Sanofi and its competitors. For the Drug Manufacturers industry, the median 1-Year ROIIC % is 1.32 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Sanofi's current 1-Year ROIIC % is -424.14. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Sanofi stock overvalued right now?
Sanofi (XSWX:SAN) has a current 1-Year ROIIC % of -424.14. The stock's GF Value™ is CHF104.30, compared to a current price of CHF73.20 — trading 29.8% below its estimated fair value. The current 1-Year ROIIC % is -424.14. Sanofi's overall GF Score™ is 87/100 with 2 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is 1-Year ROIIC % calculated?
1-Year ROIIC % is calculated from a company's financial statements. For Sanofi (XSWX:SAN), the current 1-Year ROIIC % is -424.14 as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Sanofi (XSWX:SAN) Overvalued in 2026?

Based on GuruFocus' analysis, Sanofi stock appears to be undervalued. The current stock price of CHF73.20 is trading 29.8% below its estimated GF Value™ of CHF104.30.

Key valuation signals for XSWX:SAN:

  • 1-Year ROIIC %: -424.14
  • GF Value™: CHF104.30 vs. price of CHF73.20 (29.8% below fair value)
  • GF Score™: 87/100 with 2 warning signs

No single metric tells the full story. See the XSWX:SAN stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Sanofi Business Description

Address 46, Avenue de la Great Army, Paris, FRA, 75017
Sanofi develops and markets drugs with a concentration in immunology, vaccines, and rare diseases. Although the company offers a diverse array of drugs, its highest revenue generator, Dupixent, accounts for over 30% of total sales. Profits for this immunology blockbuster drug are shared with Regeneron. About 45% of total revenue comes from the United States, 20% from Europe, and 6% from China.
87GF Score

Get the complete analysis for XSWX:SAN

1-Year ROIIC % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

CHF73.20
Price
CHF104.30
GF Value