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Dermata TherapeuticsDRMA -4.26%22 3-Year ROIIC % is 235.15 as of Dec. 2025, which is 35% below its 10-year median of 362.08. GuruFocus rates DRMA with a GF Score™ of 22/100. The stock has 2 warning signs investors should review. Among 1,319 Biotechnology companies, Dermata Therapeutics ranks better than 85.75% on this metric.
3-Year Return on Invested Incremental Capital (3-Year ROIIC %) measures the change in earnings as a percentage of change in investment over 3-year.
Dermata Therapeutics's 3-Year ROIIC % for the quarter that ended in Dec. 2025 was 235.15%. High ROIIC is generally an indication that your business is capital efficient or has a higher operating leverage.
The industry rank for Dermata Therapeutics's 3-Year ROIIC % or its related term are showing as below:
DRMA's 3-Year ROIIC % is ranked better than 85.75% of 1319
companies
in the Biotechnology industry
Industry Median: -4.85
vs DRMA: 235.15
Return on Incremental Invested Capital (ROIIC) is an extension of Return on Investment Capital (ROIC). ROIC % tells investors how efficiently that profitability is earned per dollar of company capital. ROIIC narrows the focus even further and shows how profitable each additional unit of capital investment could be. ROIIC % is a more powerful metric than ROIC because it measures how much money the company can generate going forward on future capital investments.
High ROIIC is generally an indication that your business is capital efficient or has a higher operating leverage.
Be Aware
It's important to keep in mind that when tracking ROIIC, the metric is better suited to forecasting the trend of future returns rather than measuring current return on investment.
Dermata Therapeutics 3-Year ROIIC % Related Terms
Dermata Therapeutics 3-Year ROIIC % Historical Data
* Premium members only.
The historical data trend for Dermata Therapeutics's 3-Year ROIIC % can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
DRMA vs CURX, CELZ, NCNA: 3-Year ROIIC % Comparison
For the Biotechnology subindustry, Dermata Therapeutics's 3-Year ROIIC %, along with its competitors' market caps and 3-Year ROIIC % data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
Dermata Therapeutics 3-Year ROIIC % vs Biotechnology Industry
For the Biotechnology industry and Healthcare sector, Dermata Therapeutics's 3-Year ROIIC % distribution charts can be found below:
* The bar in red indicates where Dermata Therapeutics's 3-Year ROIIC % falls into.
Dermata Therapeutics's 3-Year ROIIC % for the quarter that ended in Dec. 2025 is calculated as:
3-Year ROIIC %
=
3-Year Incremental Net Operating Profit After Taxes (NOPAT)**
/
3-Year Incremental Invested Capital**
=
( -7.774 (Dec. 2025) - -9.674 (Dec. 2022) )
/
( 0.979 (Dec. 2025) - 0.171 (Dec. 2022) )
=
1.9
/
0.808
=
235.15%***
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
** Annual data of NOPAT and Invested Capital was used to calculate 3-Year ROIIC %.
*** Please be aware that the ROIIC (Return on Invested Capital) calculations are based on company-level data using the primary share class. The calculated data provided is for demonstration purposes and may slightly differ from the results displayed in the title due to potential variations caused by currency exchange rate differences throughout the year.
Dermata Therapeutics (DRMA) has a 3-Year ROIIC % of 235.15 as of Dec. 2025. 3-Year ROIIC % measures the change in earnings as a percentage of change in investment over 3-year. View historical data on Dermata Therapeutics and its competitors. This is 35% below median its historical median of 362.08. Over the past decade, Dermata Therapeutics' 3-Year ROIIC % has ranged from 167.15 to 13,694.12. According to the industry distribution chart, Dermata Therapeutics ranks #188 out of 1319 companies in the Biotechnology industry, placing it in the top 14.3%.
Is Dermata Therapeutics' 3-Year ROIIC % too high?
Dermata Therapeutics' current 3-Year ROIIC % of 235.15 is 35% below median its 10-year median of 362.08. Over the past 10 years, this metric has ranged from a low of 167.15 to a high of 13,694.12. Based on the distribution chart, Dermata Therapeutics ranks #188 out of 1319 companies in the Biotechnology industry, which is in the top quartile — a strong position relative to peers. Overall, Dermata Therapeutics has a GF Score™ of 22/100, reflecting its overall financial health beyond just this single metric.
How does Dermata Therapeutics' 3-Year ROIIC % compare to CURX and CELZ?
According to the Biotechnology industry distribution chart, Dermata Therapeutics ranks #188 out of 1319 companies for 3-Year ROIIC %. This places Dermata Therapeutics in the top 14% of its industry — outperforming the majority of peers. Historically, Dermata Therapeutics' own 3-Year ROIIC % has ranged from 167.15 to 13,694.12 over the past decade. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good 3-Year ROIIC % for a Biotechnology company?
A good 3-Year ROIIC % depends on the Biotechnology industry context. However, 3-Year ROIIC % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high 3-Year ROIIC % mean?
A high 3-Year ROIIC % can signal that a stock is expensive relative to its fundamentals. 3-Year ROIIC % measures the change in earnings as a percentage of change in investment over 3-year. View historical data on Dermata Therapeutics and its competitors. Dermata Therapeutics's current 3-Year ROIIC % is 235.15, which is 35% below median its own 10-year median of 362.08. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Dermata Therapeutics stock overvalued right now?
Dermata Therapeutics (DRMA) has a current 3-Year ROIIC % of 235.15. The current 3-Year ROIIC % is 235.15, which is 35% below median its 10-year median of 362.08. Dermata Therapeutics' overall GF Score™ is 22/100 with 2 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is 3-Year ROIIC % calculated?
3-Year ROIIC % is calculated from a company's financial statements. For Dermata Therapeutics (DRMA), the current 3-Year ROIIC % is 235.15 as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Dermata Therapeutics Inc develops and commercializes dermatology products for the treatment of common skin conditions. It focuses on leveraging prior clinical and technical expertise to develop OTC treatments for conditions such as acne, psoriasis, rosacea, and seborrheic dermatitis. The company is currently developing a once-weekly acne treatment system that utilizes an active ingredient from the OTC monograph in combination with the company's Spongilla technology. It intends to apply its Spongilla technology platform across a range of dermatologic and aesthetic skin applications, including intradermal delivery of botulinum toxin. The company's operates in one segment, which is the business of developing, branding, marketing, and commercializing direct to consumer skincare products.
22GF Score
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