TRDA (Entrada Therapeutics) 3-Year RORE % : 181.18% (As of Mar. 2026)


TRDA Entrada Therapeutics Inc TRDA
26 GF Score
Price $7.55
GF Value $0.97
Valuation Significantly Overvalued
! 4 Warning Signs
View Full Analysis

What is Entrada Therapeutics 3-Year RORE %?

Entrada Therapeutics TRDA -2.20% 26 3-Year RORE % is 181.18 as of Mar. 2026. GuruFocus rates TRDA with a GF Score™ of 26/100 and a GF Value™ of $0.97 (Significantly Overvalued). The stock has 4 warning signs investors should review. Among 1,289 Biotechnology companies, Entrada Therapeutics ranks better than 97.98% on this metric.

Return on Retained Earnings (RORE) is an indicator of a company's growth potential, it shows how much a company earns by reinvesting its retained earnings, i.e. profits after dividend payments. Entrada Therapeutics's 3-Year RORE % for the quarter that ended in Mar. 2026 was 181.18%.

The industry rank for Entrada Therapeutics's 3-Year RORE % or its related term are showing as below:

TRDA's 3-Year RORE % is ranked better than
97.98% of 1289 companies
in the Biotechnology industry
Industry Median: -11.53 vs TRDA: 181.18

Entrada Therapeutics  (NAS:TRDA) 3-Year RORE % Explanation

Return on Retained Earnings (RORE) is important to investors because it reveals a company's efficiency and growth potential. A higher RORE indicates a higher return. A high RORE indicates that the company should reinvest profits into the business. A lower RORE suggests that the company should distribute profits to shareholders by paying out dividends, since those dollars aren't generating much additional growth for the company.

There are a several different ways to arrive at the Return on Retained Earnings. The simplest way to calculate it is by using published information on Earnings per Share (EPS) and Dividend per Share (DPS) over a selected period. Here, 3-year period is chosen.

Be Aware

Please keep in mind that the RORE is relative to the nature of the business and its competitors. If another company in the same sector is producing a lower return on retained earnings, it doesn’t necessarily mean it’s a bad investment. It may just suggest the company is older and no longer in a high growth stage. At such a stage in the business cycle, it would be expected to see a lower RORE and higher dividend payout.


Entrada Therapeutics 3-Year RORE % Related Terms


Entrada Therapeutics 3-Year RORE % Historical Data

* Premium members only.

The historical data trend for Entrada Therapeutics's 3-Year RORE % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Entrada Therapeutics 3-Year RORE % Chart

Entrada Therapeutics Annual Data
Trend Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
3-Year RORE %
Get a 7-Day Free Trial 0.00 37.10 -36.48 -359.85 176.80

Entrada Therapeutics Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
3-Year RORE % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -304.55 -57.14 104.22 176.80 181.18

TRDA vs NMRA, MGNX, CNXU: 3-Year RORE % Comparison

For the Biotechnology subindustry, Entrada Therapeutics's 3-Year RORE %, along with its competitors' market caps and 3-Year RORE % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Entrada Therapeutics 3-Year RORE % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Entrada Therapeutics's 3-Year RORE % distribution charts can be found below:

* The bar in red indicates where Entrada Therapeutics's 3-Year RORE % falls into.


TRDA
26GF Score
Entrada Therapeutics Inc TRDA
3-Year RORE % is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

Entrada Therapeutics 3-Year RORE % Calculation

Entrada Therapeutics's 3-Year RORE % for the quarter that ended in Mar. 2026 is calculated as:

3-Year RORE %=( Most Recent EPS (Diluted)- First Period EPS (Diluted) )/( Cumulative EPS (Diluted) for 3-year -Cumulative Dividends per Share for 3-year )
=( -3.99-0.63 )/( -2.55-0 )
=-4.62/-2.55
=181.18 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

In the calculation of 3-Year RORE %, the most recent and first period EPS (Diluted) is the trailing twelve months (TTM) data ended in Mar. 2026 and 3-year before.

Frequently Asked Questions Learn more about 3-Year RORE % →
What does a 3-Year RORE % of 181.18 mean?
Entrada Therapeutics (TRDA) has a 3-Year RORE % of 181.18 as of Mar. 2026. 3-Year RORE % shows how much a company earns by reinvesting its retained earnings in 3-year. View historical data on Entrada Therapeutics and its competitors. According to the industry distribution chart, Entrada Therapeutics ranks #26 out of 1289 companies in the Biotechnology industry, placing it in the top 2%.
Is Entrada Therapeutics' 3-Year RORE % too high?
Entrada Therapeutics' current 3-Year RORE % is 181.18. Based on the distribution chart, Entrada Therapeutics ranks #26 out of 1289 companies in the Biotechnology industry, which is in the top quartile — a strong position relative to peers. Overall, Entrada Therapeutics has a GF Score™ of 26/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Entrada Therapeutics' 3-Year RORE % compare to NMRA and MGNX?
According to the Biotechnology industry distribution chart, Entrada Therapeutics ranks #26 out of 1289 companies for 3-Year RORE %. This places Entrada Therapeutics in the top 2% of its industry — outperforming the majority of peers. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good 3-Year RORE % for a Biotechnology company?
A good 3-Year RORE % depends on the Biotechnology industry context. However, 3-Year RORE % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high 3-Year RORE % mean?
A high 3-Year RORE % can signal that a stock is expensive relative to its fundamentals. 3-Year RORE % shows how much a company earns by reinvesting its retained earnings in 3-year. View historical data on Entrada Therapeutics and its competitors. Entrada Therapeutics's current 3-Year RORE % is 181.18. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Entrada Therapeutics stock overvalued right now?
Based on GuruFocus' analysis, Entrada Therapeutics (TRDA) is currently considered Significantly Overvalued. The stock's GF Value™ is $0.97, compared to a current price of $7.55 — trading 678.4% above its estimated fair value. The current 3-Year RORE % is 181.18. Entrada Therapeutics' overall GF Score™ is 26/100 with 4 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is 3-Year RORE % calculated?
3-Year RORE % is calculated from a company's financial statements. For Entrada Therapeutics (TRDA), the current 3-Year RORE % is 181.18 as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Entrada Therapeutics (TRDA) Overvalued in 2026?

Based on GuruFocus' analysis, Entrada Therapeutics stock appears to be overvalued. The current stock price of $7.55 is trading 678.4% above its estimated GF Value™ of $0.97. GuruFocus considers Entrada Therapeutics to be Significantly Overvalued.

Key valuation signals for TRDA:

  • 3-Year RORE %: 181.18
  • GF Value™: $0.97 vs. price of $7.55 (678.4% above fair value)
  • GF Score™: 26/100 with 4 warning signs

No single metric tells the full story. See the TRDA stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Entrada Therapeutics Business Description

Address One Design Center Place, Suite 17-500, Boston, MA, USA, 02210
Entrada Therapeutics Inc is a clinical-stage biopharmaceutical company. It aims to transform the lives of patients by establishing a new class of medicines that engage intracellular targets that have long been considered inaccessible. The company's Endosomal Escape Vehicle (EEV)-therapeutics are designed to enable the efficient intracellular delivery into a variety of organs and tissues, resulting in an improved therapeutic index and protein-based programs for the potential treatment of neuromuscular and ocular diseases, among others. Its oligonucleotide programs are in development for the potential treatment of people living with Duchenne, which are exon 44, 45, 50, and 51 skipping amenable. It has partnered to develop a clinical-stage program, VX-670, for myotonic dystrophy type 1.
26GF Score

Get the complete analysis for TRDA

3-Year RORE % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$7.55
Price
$0.97
GF Value