PYPD (PolyPid) Shiller PE Ratio: (As of Sep. 05, 2026)

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PYPD PolyPid Ltd PYPD
32 GF Score
Price $5.38
! 1 Warning Sign
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What is PolyPid Shiller PE Ratio?

Shiller PE for Stocks: The True Measure of Stock Valuation


PolyPid  (NAS:PYPD) Shiller PE Ratio Explanation

Compared with the regular PE Ratio, which works poorly for cyclical businesses, the Shiller PE Ratio smoothed out the fluctuations of profit margins during business cycles. Therefore it is more accurate in reflecting the valuation of the company.

If a company has consistent business performance, the Shiller PE Ratio should give similar results to regular PE Ratio.

Compared with the PS Ratio, the Shiller PE Ratio makes the comparison between different industries more meaningful.


Be Aware

Shiller PE Ratio assumes that over the long term, businesses and profitability revert to their means. If a company's business model does not work in the future compared with the past, Shiller PE Ratio and PS Ratio will give false valuations.


PolyPid Shiller PE Ratio Related Terms


PolyPid Shiller PE Ratio Historical Data

* Premium members only.

The historical data trend for PolyPid's Shiller PE Ratio can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

PolyPid Shiller PE Ratio Chart

PolyPid Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Shiller PE Ratio
Get a 7-Day Free Trial Premium Member Only Premium Member Only 0.00 0.00 0.00 0.00 0.00

PolyPid Quarterly Data
Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26 Jun26
Shiller PE Ratio Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 0.00 0.00 0.00 0.00 0.00

PYPD vs PLYX, GUTS, YARW: Shiller PE Ratio Comparison

For the Biotechnology subindustry, PolyPid's Shiller PE Ratio, along with its competitors' market caps and Shiller PE Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


PolyPid Shiller PE Ratio vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, PolyPid's Shiller PE Ratio distribution charts can be found below:

* The bar in red indicates where PolyPid's Shiller PE Ratio falls into.


PYPD
32GF Score
PolyPid Ltd PYPD
Shiller PE Ratio is just one metric. See GF Score™, valuation, warning signs, and more.
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PolyPid Shiller PE Ratio Calculation

For Shiller PE Ratio, the earnings of the past 10 years are inflation-adjusted and averaged. The result is used for P/E calculation. Since it looks at the average over the last 10 years, the Shiller PE Ratio is also called PE10.

The Shiller PE Ratio was first used by professor Robert Shiller to measure the valuation of the overall market. The same calculation is applied here to individual companies.

PolyPid's E10 for the fiscal year that ended in Dec25 is calculated as:

For example, PolyPid's adjusted earnings per share data for the fiscal year that ended in Dec25 was:

Adj_EPS=Earnings per Share (Diluted)/CPI of Dec25 (Change)*Current CPI (Dec25)
=-2.09/324.0540*324.0540
=-2.090

Current CPI (Dec25) = 324.0540.

PolyPid Annual Data

Earnings per Share (Diluted) CPI Adj_EPS
201612 -38.739 241.432 -51.996
201712 -189.600 246.524 -249.228
201812 -1.206 251.233 -1.556
201912 -30.491 256.974 -38.450
202012 -134.400 260.474 -167.206
202112 -68.270 278.802 -79.351
202212 -61.090 296.797 -66.700
202312 -16.990 306.746 -17.949
202412 -4.910 315.605 -5.041
202512 -2.090 324.054 -2.090

Add all the adjusted EPS together and divide 10 will get our E10.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.


PolyPid Business Description

Other Exchanges 2PV:Germany
Address 18 Hasivim Street, Petach Tikva, ISR, 495376
PolyPid Ltd is a clinical-stage biopharmaceutical company engaged in the research and development of products based on PLEX (Polymer-Lipid Encapsulation MatriX), the company's proprietary drug delivery technology. PLEX is capable of encapsulating many types of drugs to enable targeted, localized drug delivery into the body over extended periods of time with pre-determined release rates thus optimizing drug treatment regimens. BonyPid, PolyPid, Opzifend, Ssisurg, Elyfssi, Baczenssi, Opzifend and Bacyssio are trademarks of the company. The company's product candidate include D-PLEX100 for prevention of SSI in soft tissue and OncoPLEX which can be a potential Intra-tumoral therapy.
32GF Score

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