Focused on building reliable datasets, financial models, and research tools for value-minded investors. Committed to turning complex data into practical guidance for value-investing and long-term wealth.
Dr. Charlie Tian is the founder and CEO of GuruFocus.com, a leading global investment research platform established in 2004. With a Ph.D. in physics, Dr. Tian transitioned from science to finance, applying a data-driven, disciplined approach to value investing.
Serina TherapeuticsSER -1.45%12 3-Year Share Buyback Ratio is -8.60 as of Mar. 2026. GuruFocus rates SER with a GF Score™ of 12/100. The stock has 1 warning sign investors should review. Among 1,196 Biotechnology companies, Serina Therapeutics ranks better than 56.02% on this metric.
Shares Outstanding (EOP) are shares that have been authorized, issued, and purchased by investors and are held by them.
3-Year Share Buyback Ratio measures the average annual proportion of a company's outstanding shares repurchased over the past three years. It is calculated as the annualized percentage change in shares outstanding from three years ago to the current year. A positive ratio may indicate share buybacks over the period, while a zero or negative ratio may reflect no repurchases or potential share issuance. Serina Therapeutics's current 3-Year Share Buyback Ratio was -8.60%.
The historical rank and industry rank for Serina Therapeutics's 3-Year Share Buyback Ratio or its related term are showing as below:
SER'
s 3-Year Share Buyback Ratio Range Over the Past 10 Years
Min: -8.6 Med: -6.2 Max: -3.8
Current: -8.6
During the past 5 years, Serina Therapeutics's highest 3-Year Share Buyback Ratio was -3.80%. The lowest was -8.60%. And the median was -6.20%.
SER's 3-Year Share Buyback Ratio is ranked better than 56.02% of 1196
companies
in the Biotechnology industry
Industry Median: -11.65
vs SER: -8.60
Serina Therapeutics (AMEX:SER) 3-Year Share Buyback Ratio Explanation
A negative number means the company might be issuing new shares. A positive number indicates that the company is buying back shares.
Be Aware
Investors usually like share buybacks. But as pointed by Warren Buffett, only if a company buys back shares at the prices below the stock's intrinsic value, it rewards remaining shareholders. If a company buys its overvalued stocks back, it destroys shareholder value.
Serina Therapeutics 3-Year Share Buyback Ratio Related Terms
SER vs SGMO, ABVC, PLRZ: 3-Year Share Buyback Ratio Comparison
For the Biotechnology subindustry, Serina Therapeutics's 3-Year Share Buyback Ratio, along with its competitors' market caps and 3-Year Share Buyback Ratio data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
Serina Therapeutics 3-Year Share Buyback Ratio vs Biotechnology Industry
For the Biotechnology industry and Healthcare sector, Serina Therapeutics's 3-Year Share Buyback Ratio distribution charts can be found below:
* The bar in red indicates where Serina Therapeutics's 3-Year Share Buyback Ratio falls into.
Serina Therapeutics 3-Year Share Buyback Ratio Calculation
This is the annualized percentage change in shares outstanding from three years ago to the current year. The annualized percentage change is calculated with expontential compound based on the latest four years of annual data on Shares Outstanding (EOP).
Please click Growth Rate Calculation Example (GuruFocus) to see how GuruFocus calculates Wal-Mart Stores Inc (WMT)'s revenue growth rate. You can apply the same method to get the average dividends per share growth rate.
What does a 3-Year Share Buyback Ratio of -8.60 mean?
Serina Therapeutics (SER) has a 3-Year Share Buyback Ratio of -8.60 as of Mar. 2026. The 3-Year Share Buyback Ratio measures the average annual proportion of a company's outstanding shares repurchased over the past three years. It is calculated as the annualized percentage change in shares outstanding from three years ago to the current year. View historical data for Serina Therapeutics and its competitors. According to the industry distribution chart, Serina Therapeutics ranks #526 out of 1196 companies in the Biotechnology industry, placing it in the top 44%.
Is Serina Therapeutics' 3-Year Share Buyback Ratio too high?
Serina Therapeutics' current 3-Year Share Buyback Ratio is -8.60. Based on the distribution chart, Serina Therapeutics ranks #526 out of 1196 companies in the Biotechnology industry, which is above the industry midpoint. Overall, Serina Therapeutics has a GF Score™ of 12/100, reflecting its overall financial health beyond just this single metric.
How does Serina Therapeutics' 3-Year Share Buyback Ratio compare to SGMO and ABVC?
According to the Biotechnology industry distribution chart, Serina Therapeutics ranks #526 out of 1196 companies for 3-Year Share Buyback Ratio. This puts Serina Therapeutics in the upper half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good 3-Year Share Buyback Ratio for a Biotechnology company?
A good 3-Year Share Buyback Ratio depends on the Biotechnology industry context. However, 3-Year Share Buyback Ratio should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high 3-Year Share Buyback Ratio mean?
A high 3-Year Share Buyback Ratio can signal that a stock is expensive relative to its fundamentals. The 3-Year Share Buyback Ratio measures the average annual proportion of a company's outstanding shares repurchased over the past three years. It is calculated as the annualized percentage change in shares outstanding from three years ago to the current year. View historical data for Serina Therapeutics and its competitors. Serina Therapeutics's current 3-Year Share Buyback Ratio is -8.60. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Serina Therapeutics stock overvalued right now?
Serina Therapeutics (SER) has a current 3-Year Share Buyback Ratio of -8.60. The current 3-Year Share Buyback Ratio is -8.60. Serina Therapeutics' overall GF Score™ is 12/100 with 1 warning sign to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is 3-Year Share Buyback Ratio calculated?
3-Year Share Buyback Ratio is calculated from a company's financial statements. For Serina Therapeutics (SER), the current 3-Year Share Buyback Ratio is -8.60 as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Serina Therapeutics Inc is a clinical-stage biotechnology company developing a pipeline of wholly-owned drug product candidates to treat neurological diseases and pain. Serina's POZ Platform delivery technology is engineered to provide control in drug loading and more precision in the rate of release of attached drugs, enabling the potential of certain challenging small molecules, while addressing the limitations of polyethylene glycol (PEG) and other biocompatible polymers. The company has one reportable segment relating to the research and development of its POZ platform. The segment derives its revenues from Grant revenue. Its main product candidate, SER-252 for advanced Parkinson's disease, is anticipated to enter clinical trials.
12GF Score
Get the complete analysis for SER
3-Year Share Buyback Ratio is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.
Quick Browse
Personalize
Premium Gurus 
Create New Portfolio
SER has been successfully added to your 
