ALXO (ALX Oncology Holdings) Volatility: 132.48% (As of Aug. 25, 2026)

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Charlie Tian
Founder & CEO of GuruFocus
Dr. Charlie Tian is the founder and CEO of GuruFocus.com, a leading global investment research platform established in 2004. With a Ph.D. in physics, Dr. Tian transitioned from science to finance, applying a data-driven, disciplined approach to value investing.

ALXO ALX Oncology Holdings Inc ALXO
27 GF Score
Price $1.98
! 3 Warning Signs
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What is ALX Oncology Holdings Volatility?

ALX Oncology Holdings ALXO -2.21% 27 Volatility is 132.48% as of Aug. 25, 2026. GuruFocus rates ALXO with a GF Score™ of 27/100. The stock has 3 warning signs investors should review.

Volatility is a statistical measure of the dispersion of returns for a given security or market index, it shows how the price swings around its mean. The volatility here is measured as the annualized standard deviation between monthly returns from the security over the past year. In most cases, the higher the volatility, the riskier the security.

As of today (2026-08-25), ALX Oncology Holdings's Volatility is 132.48%.


ALX Oncology Holdings  (NAS:ALXO) Volatility Explanation

Volatility is a statistical measure of the dispersion of returns for a given security or market index. It’s often measured as standard deviation or variance of historical returns over a certain period. The volatility here is measured as the annualized standard deviation between monthly returns from the security over the past year.

Volatility reflects the uncertainty or risk of a security’s value. Generally speaking, a higher volatility suggests a higher risk, because it implies a wider fluctuation around average price. This means the price of the security can change dramatically in either direction within a short period. Conversely, a lower volatility means that the security's price is more steady, which suggests a lower risk.

Another measurement of relative volatility is Beta. Beta is a measure of systematic risk of a security or a portfolio in comparison to the market as a whole. Beta is usually compared to 1. A beta of greater than 1 indicates that the security's price will be more volatile than the market.


ALX Oncology Holdings Volatility Related Terms


ALXO vs CYDY, BCYC, ELDN: Volatility Comparison

For the Biotechnology subindustry, ALX Oncology Holdings's Volatility, along with its competitors' market caps and Volatility data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


ALX Oncology Holdings Volatility vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, ALX Oncology Holdings's Volatility distribution charts can be found below:

* The bar in red indicates where ALX Oncology Holdings's Volatility falls into.


ALXO
27GF Score
ALX Oncology Holdings Inc ALXO
Volatility is just one metric. See GF Score™, valuation, warning signs, and more.
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ALX Oncology Holdings  (NAS:ALXO) Volatility Calculation

The annualized volatility is calculated as following:

σA=σM * 12
= 1/(n-1) ∑(Ri - R')^2 * 12

Where: σM is the monthly volatility, n is the number of months in the period, Ri is the security's historical monthly returns and R' is the arithmetic mean of monthly returns.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about Volatility →
What does a Volatility of 132.48% mean?
ALX Oncology Holdings (ALXO) has a Volatility of 132.48% as of Aug. 25, 2026. Volatility is measured as the annualized standard deviation between monthly returns from the security over the past year. View historical data on ALX Oncology Holdings and its competitors.
Is ALX Oncology Holdings' Volatility too high?
ALX Oncology Holdings' current Volatility is 132.48%. Overall, ALX Oncology Holdings has a GF Score™ of 27/100, reflecting its overall financial health beyond just this single metric.
How does ALX Oncology Holdings' Volatility compare to CYDY and BCYC?
ALX Oncology Holdings' Volatility of 132.48% can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Volatility for a Biotechnology company?
A good Volatility depends on the Biotechnology industry context. However, Volatility should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Volatility mean?
A high Volatility can signal that a stock is expensive relative to its fundamentals. Volatility is measured as the annualized standard deviation between monthly returns from the security over the past year. View historical data on ALX Oncology Holdings and its competitors. ALX Oncology Holdings's current Volatility is 132.48%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is ALX Oncology Holdings stock overvalued right now?
ALX Oncology Holdings (ALXO) has a current Volatility of 132.48%. The current Volatility is 132.48%. ALX Oncology Holdings' overall GF Score™ is 27/100 with 3 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Volatility calculated?
Volatility is calculated from a company's financial statements. For ALX Oncology Holdings (ALXO), the current Volatility is 132.48% as of Aug. 25, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

ALX Oncology Holdings Business Description

Address 323 Allerton Avenue, South San Francisco, CA, USA, 94080
ALX Oncology Holdings Inc is a clinical-stage immuno-oncology company focused on helping patients fight cancer by developing a pipeline of product candidates based on expertise in protein engineering and oncology led by the CD47 blocker, evorpacept, currently in phase 1 and 2 clinical trials. Cancer cells leverage CD47, a cell surface protein, as a don't eat me signal to evade detection by the immune system. It is developing a next-generation checkpoint inhibitor designed to have a high affinity for CD47 and to avoid the limitations caused by hematologic toxicities inherent in other CD47 blocking approaches.
27GF Score

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Volatility is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$1.98
Price