Sphera Funds Management Ltd. Buys AbbVie Inc, NICE, Amgen Inc, Sells Alexion Pharmaceuticals Inc, Pfizer Inc, Sarepta Therapeutics Inc

• New Purchases: NICE, AMGN, LLY, RETA, FIXX, WIX, MYOK, IOVA, PASG, KRNT, FISV, KURA, MRTX, FATE, RPTX, SEDG, APRE, KRYS, DOV, DPZ, LRMR, RTRX, ARYBU, CPRX, GRTX, ENPH, WVE, CGEN, SLNO, PRGO, IMVT, AKUS, AKBA, MEIP, NBSE, IMUX, BLU, TCRR, CAMT,
• Added Positions: ABBV, AZN, DCPH, SNY, FVRR, NVS, PANW, TEVA, SNDX, ALLT, LPTX, ISEE, ADMA, ASND, RCKT,
• Reduced Positions: SRPT, NVO, MRK, JNJ, BMY, QURE, FOLD, ZYME, XFOR, KPTI, CNCE, XCUR, AMZN, MSFT, VKTX, ORGS, NEOS, YMAB, TRIL, AXGT,
• Sold Out: ALXN, PFE, XLP, ACAD, BPMC, ARVN, CRM, AUDC, NLTX, PTGX, PTI, ALDX, SAVA, ZFGN, EOLS, PRQR, VRTX, GBT, NERV, APTX, DTIL, ALNA, STOK, ZYNE, SNSS, CYCN, MIST,

For the details of SPHERA FUNDS MANAGEMENT LTD.'s stock buys and sells, go to https://www.gurufocus.com/guru/sphera+funds+management+ltd./current-portfolio/portfolio

1. SPDR SERIES TRUST (XBI) - 750,000 shares, 7.90% of the total portfolio.
2. AbbVie Inc (ABBV) - 734,598 shares, 6.79% of the total portfolio. Shares added by 345.21%
3. Merck & Co Inc (MRK) - 783,808 shares, 5.70% of the total portfolio. Shares reduced by 9.75%
4. SPDR S&P500 ETF TR (SPY) - 189,000 shares, 5.48% of the total portfolio.
5. Sanofi SA (SNY) - 1,120,000 shares, 5.38% of the total portfolio. Shares added by 15.46%

Sphera Funds Management Ltd. initiated holding in NICE Ltd. The purchase prices were between $140.88 and $196.74, with an estimated average price of $174.54. The stock is now traded at around $223.51. The impact to a portfolio due to this purchase was 2.3%. The holding were 129,406 shares as of .

Sphera Funds Management Ltd. initiated holding in Amgen Inc. The purchase prices were between $197.81 and $242.74, with an estimated average price of $227.6. The stock is now traded at around $241.50. The impact to a portfolio due to this purchase was 1.78%. The holding were 80,000 shares as of .

Sphera Funds Management Ltd. initiated holding in Eli Lilly and Co. The purchase prices were between $136.42 and $164.18, with an estimated average price of $153.12. The stock is now traded at around $153.11. The impact to a portfolio due to this purchase was 1.39%. The holding were 90,000 shares as of .

Sphera Funds Management Ltd. initiated holding in Reata Pharmaceuticals Inc. The purchase prices were between $126.3 and $176.56, with an estimated average price of $151.86. The stock is now traded at around $107.71. The impact to a portfolio due to this purchase was 1.2%. The holding were 82,049 shares as of .

Sphera Funds Management Ltd. initiated holding in Homology Medicines Inc. The purchase prices were between $12.07 and $19.34, with an estimated average price of $14.89. The stock is now traded at around $11.18. The impact to a portfolio due to this purchase was 0.94%. The holding were 658,919 shares as of .

Sphera Funds Management Ltd. initiated holding in MyoKardia Inc. The purchase prices were between $44.2 and $121.69, with an estimated average price of $82.77. The stock is now traded at around $101.14. The impact to a portfolio due to this purchase was 0.91%. The holding were 100,000 shares as of .

Sphera Funds Management Ltd. added to a holding in AbbVie Inc by 345.21%. The purchase prices were between $73.37 and $98.18, with an estimated average price of $87.8. The stock is now traded at around $95.65. The impact to a portfolio due to this purchase was 5.26%. The holding were 734,598 shares as of .

Sphera Funds Management Ltd. added to a holding in AstraZeneca PLC by 56.14%. The purchase prices were between $43.1 and $55.31, with an estimated average price of $51.48. The stock is now traded at around $56.33. The impact to a portfolio due to this purchase was 1.59%. The holding were 890,000 shares as of .

Sphera Funds Management Ltd. added to a holding in Deciphera Pharmaceuticals Inc by 136.79%. The purchase prices were between $37.05 and $65.03, with an estimated average price of $53.24. The stock is now traded at around $44.61. The impact to a portfolio due to this purchase was 0.92%. The holding were 282,965 shares as of .

Sphera Funds Management Ltd. added to a holding in Fiverr International Ltd by 59.29%. The purchase prices were between $22.94 and $74.01, with an estimated average price of $50.8. The stock is now traded at around $115.93. The impact to a portfolio due to this purchase was 0.43%. The holding were 167,002 shares as of .

Sphera Funds Management Ltd. added to a holding in Novartis AG by 28.57%. The purchase prices were between $80.93 and $91.1, with an estimated average price of $86.22. The stock is now traded at around $85.63. The impact to a portfolio due to this purchase was 0.33%. The holding were 180,000 shares as of .

Sphera Funds Management Ltd. added to a holding in Palo Alto Networks Inc by 82.35%. The purchase prices were between $162.66 and $239.86, with an estimated average price of $210.57. The stock is now traded at around $265.76. The impact to a portfolio due to this purchase was 0.29%. The holding were 30,000 shares as of .

Sphera Funds Management Ltd. sold out a holding in Alexion Pharmaceuticals Inc. The sale prices were between $89.77 and $119.9, with an estimated average price of $105.7.

Sphera Funds Management Ltd. sold out a holding in Pfizer Inc. The sale prices were between $31.75 and $38.51, with an estimated average price of $35.78.

Sphera Funds Management Ltd. sold out a holding in SELECT SECTOR SPDR. The sale prices were between $53.55 and $61.07, with an estimated average price of $58.29.

Sphera Funds Management Ltd. sold out a holding in ACADIA Pharmaceuticals Inc. The sale prices were between $39.26 and $52.73, with an estimated average price of $47.9.

Sphera Funds Management Ltd. sold out a holding in Blueprint Medicines Corp. The sale prices were between $57.09 and $79.27, with an estimated average price of $67.44.

Sphera Funds Management Ltd. sold out a holding in Arvinas Inc. The sale prices were between $29.88 and $56.74, with an estimated average price of $42.5.