Ionis Pharmaceuticals (MEX:IONS) Cash Flow from Operations: MXN-9,319 Mil (TTM As of Jun. 2026)

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MEX:IONS Ionis Pharmaceuticals Inc MEX:IONS
72 GF Score
Price MXN1,150.00
GF Value MXN1,016.09
! 5 Warning Signs
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What is Ionis Pharmaceuticals Cash Flow from Operations?

Ionis Pharmaceuticals MEX:IONS 72 Cash Flow from Operations is MXN-9,319 Mil as of Jun. 2026. GuruFocus rates MEX:IONS with a GF Score™ of 72/100 and a GF Value™ of MXN1,016.09. The stock has 5 warning signs investors should review.

Cash flow from operations refers to the cash brought in through a company's normal business operations. It is the cash flow before any investment or financing activities. It is the cash version of net income.

For the three months ended in Jun. 2026, Ionis Pharmaceuticals's Net Income From Continuing Operations was MXN-2,000 Mil. Its Depreciation, Depletion and Amortization was MXN133 Mil. Its Change In Working Capital was MXN10,665 Mil. Its cash flow from deferred tax was MXN0 Mil. Its Cash from Discontinued Operating Activities was MXN0 Mil. Its Asset Impairment Charge was MXN0 Mil. Its Stock Based Compensation was MXN796 Mil. And its Cash Flow from Others was MXN275 Mil. In all, Ionis Pharmaceuticals's Cash Flow from Operations for the three months ended in Jun. 2026 was MXN9,868 Mil.


Ionis Pharmaceuticals  (MEX:IONS) Cash Flow from Operations Explanation

For companies reported in indirect method, cash flow from operations contains six items:

1. Net Income From Continuing Operations:
Net Income From Continuing Operations indicates the net income that a firm brings in from ongoing business activities. These activities are expected to continue into the next reporting period. It excludes extraordinary items, income from the cumulative effects of accounting changes, non-recurring items, income from tax loss carry forward, and preferred dividends.

Ionis Pharmaceuticals's net income from continuing operations for the three months ended in Jun. 2026 was MXN-2,000 Mil.

2. Depreciation, Depletion and Amortization:
Depreciation is a present expense that accounts for the past cost of an asset that is now providing benefits.
Depletion and amortization are synonyms for depreciation.
Generally:
The term depreciation is used when discussing man made tangible assets
The term depletion is used when discussing natural tangible assets
The term amortization is used when discussing intangible assets

Ionis Pharmaceuticals's depreciation, depletion and amortization for the three months ended in Jun. 2026 was MXN133 Mil.

3. Change In Working Capital:
Working Capital is a measure of a company's short term liquidity or its ability to cover short term liabilities. It is defined as the difference between a company's current assets and current liabilities. Changes in Working Capital is reported in the cash flow statement since it is one of the major ways in which net income can differ from operating cash flow.

Ionis Pharmaceuticals's change in working capital for the three months ended in Jun. 2026 was MXN10,665 Mil. It means Ionis Pharmaceuticals's working capital increased by MXN10,665 Mil from Mar. 2026 to Jun. 2026 .

4. Deferred Tax:
It is the cash flow generated from deferred tax.

Ionis Pharmaceuticals's cash flow from deferred tax for the three months ended in Jun. 2026 was MXN0 Mil.

5. Cash from Discontinued Operating Activities:
Net cash from all of the entity's discontinued operating activities.

Ionis Pharmaceuticals's cash from discontinued operating Activities for the three months ended in Jun. 2026 was MXN0 Mil.

6. Asset Impairment Charge:
It is the charge against earnings resulting from the aggregate write down of all assets from their carrying value to their fair value.

Ionis Pharmaceuticals's asset impairment charge for the three months ended in Jun. 2026 was MXN0 Mil.

7. Stock Based Compensation:
It is a way corporations use stock options to reward employees. It provides executives and employees the opportunity to share in the growth of the company and, if structured properly, can align their interests with the interests of the company's shareholders and investors, without burning the company's cash on hand.

Ionis Pharmaceuticals's stock based compensation for the three months ended in Jun. 2026 was MXN796 Mil.

8. Cash Flow from Others:
These are cash differences caused by the change of inventory, accounts payable, accounts receivable etc. For instance, if a company pays its suppliers slower, its cash position will build up faster. If a company receives payments from its customers slower, its account receivables will rise, and its cash position will grow more slowly (or even shrink).

Ionis Pharmaceuticals's cash flow from others for the three months ended in Jun. 2026 was MXN275 Mil.


Ionis Pharmaceuticals Cash Flow from Operations Related Terms


Ionis Pharmaceuticals Cash Flow from Operations Historical Data

* Premium members only.

The historical data trend for Ionis Pharmaceuticals's Cash Flow from Operations can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Ionis Pharmaceuticals Cash Flow from Operations Chart

Ionis Pharmaceuticals Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Cash Flow from Operations
Get a 7-Day Free Trial Premium Member Only Premium Member Only 631.81 -5,349.12 -5,219.80 -10,447.60 -4,836.03

Ionis Pharmaceuticals Quarterly Data
Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26 Jun26
Cash Flow from Operations Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 2,849.57 -2,411.11 -2,479.55 -14,296.67 9,867.95
MEX:IONS
72GF Score
Ionis Pharmaceuticals Inc MEX:IONS
Cash Flow from Operations is just one metric. See GF Score™, valuation, warning signs, and more.
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Ionis Pharmaceuticals Cash Flow from Operations Calculation

Cash flow from operations refers to the cash brought in through a company's normal business operations. It is the cash flow before any investment or financing activities. It is the cash version of net income.

Ionis Pharmaceuticals's Cash Flow from Operations for the fiscal year that ended in Dec. 2025 is calculated as:

Ionis Pharmaceuticals's Cash Flow from Operations for the quarter that ended in Jun. 2026 is:


Cash Flow from Operations for the trailing twelve months (TTM) ended in Jun. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was MXN-9,319 Mil.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

What does a Cash Flow from Operations of MXN-9,319 Mil mean?
Ionis Pharmaceuticals (MEX:IONS) has a Cash Flow from Operations of MXN-9,319 Mil as of Jun. 2026. Cash Flow from Operations is the amount of cash earned or paid from standard business operations. View historical data for Ionis Pharmaceuticals and its competitors.
Is Ionis Pharmaceuticals' Cash Flow from Operations too high?
Ionis Pharmaceuticals' current Cash Flow from Operations is MXN-9,319 Mil. Overall, Ionis Pharmaceuticals has a GF Score™ of 72/100, reflecting its overall financial health beyond just this single metric.
How does Ionis Pharmaceuticals' Cash Flow from Operations compare to KYMR and PRAX?
Ionis Pharmaceuticals' Cash Flow from Operations of MXN-9,319 Mil can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Cash Flow from Operations for a Biotechnology company?
A good Cash Flow from Operations depends on the Biotechnology industry context. However, Cash Flow from Operations should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Cash Flow from Operations mean?
A high Cash Flow from Operations can signal that a stock is expensive relative to its fundamentals. Cash Flow from Operations is the amount of cash earned or paid from standard business operations. View historical data for Ionis Pharmaceuticals and its competitors. Ionis Pharmaceuticals's current Cash Flow from Operations is MXN-9,319 Mil. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Ionis Pharmaceuticals stock overvalued right now?
Ionis Pharmaceuticals (MEX:IONS) has a current Cash Flow from Operations of MXN-9,319 Mil. The stock's GF Value™ is MXN1,016.09, compared to a current price of MXN1,150.00 — trading 13.2% above its estimated fair value. The current Cash Flow from Operations is MXN-9,319 Mil. Ionis Pharmaceuticals' overall GF Score™ is 72/100 with 5 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Cash Flow from Operations calculated?
Cash Flow from Operations is calculated from a company's financial statements. For Ionis Pharmaceuticals (MEX:IONS), the current Cash Flow from Operations is MXN-9,319 Mil as of Jun. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Ionis Pharmaceuticals (MEX:IONS) Overvalued in 2026?

Based on GuruFocus' analysis, Ionis Pharmaceuticals stock appears to be overvalued. The current stock price of MXN1,150.00 is trading 13.2% above its estimated GF Value™ of MXN1,016.09.

Key valuation signals for MEX:IONS:

  • Cash Flow from Operations: MXN-9,319 Mil
  • GF Value™: MXN1,016.09 vs. price of MXN1,150.00 (13.2% above fair value)
  • GF Score™: 72/100 with 5 warning signs

No single metric tells the full story. See the MEX:IONS stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Ionis Pharmaceuticals Business Description

Address 2855 Gazelle Court, Carlsbad, CA, USA, 92010
Ionis Pharmaceuticals is the leading developer of antisense technology to discover and develop novel drugs. Its broad clinical and preclinical pipeline targets a wide variety of diseases, with an emphasis on cardiovascular, metabolic, neurological, and rare diseases. Ionis and Biogen brought Spinraza to market in 2016 as a treatment for spinal muscular atrophy, and Biogen launched ALS drug Qalsody in 2023. Ionis brought two additional drugs to market via its cardiovascular-focused subsidiary Akcea, including ATTR amyloidosis drug Tegsedi (2018) and cardiology drug Waylivra (Europe, 2019). Ionis and AstraZeneca launched polyneuropathy drug Wainua in 2024. Ionis marked its first two independent launches in 2025 for Tryngolza (for FCS) and Dawnzera (for HAE).
72GF Score

Get the complete analysis for MEX:IONS

Cash Flow from Operations is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

MXN1,150.00
Price
MXN1,016.09
GF Value