AVXL (Anavex Life Sciences) Cyclically Adjusted Book per Share: $1.15 (As of Dec. 2025)


AVXL Anavex Life Sciences Corp AVXL
30 GF Score
Price $2.60
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What is Anavex Life Sciences Cyclically Adjusted Book per Share?

Anavex Life Sciences AVXL -0.57% 30 Cyclically Adjusted Book per Share is $1.15 as of Dec. 2025. GuruFocus rates AVXL with a GF Score™ of 30/100. The stock has 1 warning sign investors should review.

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted Book per Share and the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted Book Value per Share of a company over the past 10 years.

Anavex Life Sciences's adjusted book value per share for the three months ended in Dec. 2025 was $1.366. Add all the adjusted book value per share for the past 10 years together and divide the count will get our Cyclically Adjusted Book per Share, which is $1.15 for the trailing ten years ended in Dec. 2025.

During the past 12 months, Anavex Life Sciences's average Cyclically Adjusted Book Growth Rate was 10.80% per year. During the past 3 years, the average Cyclically Adjusted Book Growth Rate was 21.50% per year. During the past 5 years, the average Cyclically Adjusted Book Growth Rate was 43.60% per year. Please click Growth Rate Calculation Example (GuruFocus) to see how GuruFocus calculates Wal-Mart Stores Inc (WMT)'s revenue growth rate. You can apply the same method to get the Cyclically Adjusted Book Growth Rate using Cyclically Adjusted Book per Share data.

During the past 13 years, the highest 3-Year average Cyclically Adjusted Book Growth Rate of Anavex Life Sciences was 175.90% per year. The lowest was 18.00% per year. And the median was 36.10% per year.

As of today (2026-06-30), Anavex Life Sciences's current stock price is $2.595. Anavex Life Sciences's Cyclically Adjusted Book per Share for the quarter that ended in Dec. 2025 was $1.15. Anavex Life Sciences's Cyclically Adjusted PB Ratio of today is 2.26.

During the past 13 years, the highest Cyclically Adjusted PB Ratio of Anavex Life Sciences was 2.26. The lowest was 0.00. And the median was 0.00.


Anavex Life Sciences  (NAS:AVXL) Cyclically Adjusted Book per Share Explanation

If a company grows much fast than inflation, Cyclically Adjusted Book per Share may underestimate the company's equity. Cyclically Adjusted PB Ratio can seem to be too high even the actual PB Ratio is low.

For the Cyclically Adjusted PB Ratio, the book value of the past 10 years are inflation-adjusted and averaged. The result is used for P/B calculation. Since it looks at the average over the last 10 years, the Cyclically Adjusted PB Ratio is also called CAPB Ratio.

The Shiller PE Ratio was first used by professor Robert Shiller. He uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings per share of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted book value per share of a company over the past 10 years.

Anavex Life Sciences's Cyclically Adjusted PB Ratio of today is calculated as

Cyclically Adjusted PB Ratio=Share Price/Cyclically Adjusted Book per Share
=2.595/1.15
=2.26

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

During the past 13 years, the highest Cyclically Adjusted PB Ratio of Anavex Life Sciences was 2.26. The lowest was 0.00. And the median was 0.00.


Be Aware

Cyclically Adjusted PB Ratio works better for cyclical companies. It gives you a better idea on the company's real book value.


Anavex Life Sciences Cyclically Adjusted Book per Share Related Terms


Anavex Life Sciences Cyclically Adjusted Book per Share Historical Data

* Premium members only.

The historical data trend for Anavex Life Sciences's Cyclically Adjusted Book per Share can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Anavex Life Sciences Cyclically Adjusted Book per Share Chart

Anavex Life Sciences Annual Data
Trend Sep16 Sep17 Sep18 Sep19 Sep20 Sep21 Sep22 Sep23 Sep24 Sep25
Cyclically Adjusted Book per Share
Get a 7-Day Free Trial Premium Member Only Premium Member Only 0.36 0.63 0.89 1.02 1.13

Anavex Life Sciences Quarterly Data
Mar21 Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25
Cyclically Adjusted Book per Share Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 1.05 1.08 1.11 1.13 1.15

AVXL vs SLGL, FATE, FHTX: Cyclically Adjusted Book per Share Comparison

For the Biotechnology subindustry, Anavex Life Sciences's Cyclically Adjusted PB Ratio, along with its competitors' market caps and Cyclically Adjusted PB Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Anavex Life Sciences Cyclically Adjusted PB Ratio vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Anavex Life Sciences's Cyclically Adjusted PB Ratio distribution charts can be found below:

* The bar in red indicates where Anavex Life Sciences's Cyclically Adjusted PB Ratio falls into.


AVXL
30GF Score
Anavex Life Sciences Corp AVXL
Cyclically Adjusted Book per Share is just one metric. See GF Score™, valuation, warning signs, and more.
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Anavex Life Sciences Cyclically Adjusted Book per Share Calculation

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted Book per Share and the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted Book Value per Share of a company over the past 10 years.

What is Cyclically Adjusted Book per Share? How do we calculate Cyclically Adjusted Book per Share?

Cyclically Adjusted Book per Share is the average of the inflation adjusted Book Value per Share of a company over the past 10 years. Let's use an example to explain.

If we want to calculate the Cyclically Adjusted Book per Share of Wal-Mart (WMT) for Dec. 31, 2010, we need to have the inflation data and the book value per share from 2001 through 2010.

We adjusted the 2001 book value per share data with the total inflation from 2001 through 2010 to the equivalent book value in 2010. If the total inflation from 2001 to 2010 is 40%, and Wal-Mart's book value is $1 a share in 2001, then the 2001's equivalent book value in 2010 is $1.4 a share. If Wal-Mart's book value is $1 again in 2002, and the total inflation from 2002 through 2010 is 35%, then the equivalent 2002 book value in 2010 is $1.35. So on and so forth, you get the equivalent book value per share of past 10 years. Then you add them together and divided the sum by the count to get Cyclically Adjusted Book per Share.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

For example, Anavex Life Sciences's adjusted Book Value per Share data for the three months ended in Dec. 2025 was:

Adj_Book= Book Value per Share /CPI of Dec. 2025 (Change)*Current CPI (Dec. 2025)
=1.366/324.0540*324.0540
=1.366

Current CPI (Dec. 2025) = 324.0540.

Anavex Life Sciences Quarterly Data

Book Value per Share CPI Adj_Book
201603 0.271 238.132 0.369
201606 0.215 241.018 0.289
201609 0.174 241.428 0.234
201612 0.472 241.432 0.634
201703 0.519 243.801 0.690
201706 0.556 244.955 0.736
201709 0.560 246.819 0.735
201712 0.575 246.524 0.756
201803 0.504 249.554 0.654
201806 0.521 251.989 0.670
201809 0.486 252.439 0.624
201812 0.367 251.233 0.473
201903 0.294 254.202 0.375
201906 0.342 256.143 0.433
201909 0.385 256.759 0.486
201912 0.455 256.974 0.574
202003 0.423 258.115 0.531
202006 0.411 257.797 0.517
202009 0.439 260.280 0.547
202012 0.691 260.474 0.860
202103 1.083 264.877 1.325
202106 2.076 271.696 2.476
202109 1.987 274.310 2.347
202112 1.922 278.802 2.234
202203 1.973 287.504 2.224
202206 1.934 296.311 2.115
202209 1.828 296.808 1.996
202212 1.732 296.797 1.891
202303 1.809 301.836 1.942
202306 1.803 305.109 1.915
202309 1.728 307.789 1.819
202312 1.652 306.746 1.745
202403 1.614 312.332 1.675
202406 1.531 314.175 1.579
202409 1.418 315.301 1.457
202412 1.305 315.605 1.340
202503 1.169 319.799 1.185
202506 1.065 322.561 1.070
202509 1.095 324.800 1.092
202512 1.366 324.054 1.366

Add all the adjusted book value per share together and divide the count will get our Cyclically Adjusted Book per Share.

What does a Cyclically Adjusted Book per Share of $1.15 mean?
Anavex Life Sciences (AVXL) has a Cyclically Adjusted Book per Share of $1.15 as of Dec. 2025. Cyclically adjusted book value per share represents the company's inflation-adjusted book value per share over a 10-year period. View historical data on Anavex Life Sciences and its competitors.
Is Anavex Life Sciences' Cyclically Adjusted Book per Share too high?
Anavex Life Sciences' current Cyclically Adjusted Book per Share is $1.15. Overall, Anavex Life Sciences has a GF Score™ of 30/100, reflecting its overall financial health beyond just this single metric.
How does Anavex Life Sciences' Cyclically Adjusted Book per Share compare to SLGL and FATE?
Anavex Life Sciences' Cyclically Adjusted Book per Share of $1.15 can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Cyclically Adjusted Book per Share for a Biotechnology company?
A good Cyclically Adjusted Book per Share depends on the Biotechnology industry context. However, Cyclically Adjusted Book per Share should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Cyclically Adjusted Book per Share mean?
A high Cyclically Adjusted Book per Share can signal that a stock is expensive relative to its fundamentals. Cyclically adjusted book value per share represents the company's inflation-adjusted book value per share over a 10-year period. View historical data on Anavex Life Sciences and its competitors. Anavex Life Sciences's current Cyclically Adjusted Book per Share is $1.15. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Anavex Life Sciences stock overvalued right now?
Anavex Life Sciences (AVXL) has a current Cyclically Adjusted Book per Share of $1.15. The current Cyclically Adjusted Book per Share is $1.15. Anavex Life Sciences' overall GF Score™ is 30/100 with 1 warning sign to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Cyclically Adjusted Book per Share calculated?
Cyclically Adjusted Book per Share is calculated from a company's financial statements. For Anavex Life Sciences (AVXL), the current Cyclically Adjusted Book per Share is $1.15 as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Anavex Life Sciences Business Description

Other Exchanges 0HFR:UK12X1:Germany
Address 630 5th Avenue, 20th Floor, New York, NY, USA, 10111
Anavex Life Sciences Corp is a clinical stage biopharmaceutical company engaged in the development of differentiated therapeutics by applying precision medicine to central nervous system(CNS) diseases with high unmet need. It analyzes genomic data from clinical trials to identify biomarkers, which are used in the analysis of its clinical trials for the treatment of neurodegenerative and neurodevelopmental diseases. The company focuses on developing treatments for Alzheimer's disease, Parkinson's disease, schizophrenia, neurodevelopmental, neurodegenerative, and rare diseases, including Rett syndrome, and other central nervous system (CNS) disorders. Its pipeline includes ANAVEX 2-73 and ANAVEX 3-71 and several other compounds in different stages of clinical and pre-clinical development.
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