AVXL (Anavex Life Sciences) ROA %: -19.19% (As of Dec. 2025)


AVXL Anavex Life Sciences Corp AVXL
30 GF Score
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What is Anavex Life Sciences ROA %?

Anavex Life Sciences AVXL -0.97% 30 ROA % is -19.19% as of Dec. 2025. GuruFocus rates AVXL with a GF Score™ of 30/100. The stock has 1 warning sign investors should review. Among 1,423 Biotechnology companies, Anavex Life Sciences ranks worse than 51.65% on this metric.

ROA % is calculated as Net Income divided by its average Total Assets over a certain period of time. Anavex Life Sciences's annualized Net Income for the quarter that ended in Dec. 2025 was $-22.72 Mil. Anavex Life Sciences's average Total Assets over the quarter that ended in Dec. 2025 was $118.40 Mil. Therefore, Anavex Life Sciences's annualized ROA % for the quarter that ended in Dec. 2025 was -19.19%.

The historical rank and industry rank for Anavex Life Sciences's ROA % or its related term are showing as below:

AVXL' s ROA % Range Over the Past 10 Years
Min: -118.04   Med: -51.3   Max: -29.66
Current: -34.41

During the past 13 years, Anavex Life Sciences's highest ROA % was -29.66%. The lowest was -118.04%. And the median was -51.30%.

AVXL's ROA % is ranked worse than
51.65% of 1423 companies
in the Biotechnology industry
Industry Median: -33.07 vs AVXL: -34.41

Anavex Life Sciences  (NAS:AVXL) ROA % Explanation

ROA % measures the rate of return on the total assets (shareholder equity plus liabilities). It measures a firm's efficiency at generating profits from shareholders' equity plus its liabilities. ROA % shows how well a company uses what it has to generate earnings. ROA %s can vary drastically across industries. Therefore, ROA % should not be used to compare companies in different industries. For retailers, a ROA % of higher than 5% is expected. For example, Wal-Mart (WMT) has a ROA % of about 8% as of 2012. For banks, ROA % is close to their interest spread. A bank’s ROA % is typically well under 2%.

Similar to ROE, ROA % is affected by profit margins and asset turnover. This can be seen from the Du Pont Formula:

ROA %(Q: Dec. 2025 )
=Net Income/Total Assets
=-22.724/118.402
=(Net Income / Revenue)*(Revenue / Total Assets)
=(-22.724 / 0)*(0 / 118.402)
=Net Margin %*Asset Turnover
=N/A %*0
=-19.19 %

Note: The Net Income data used here is four times the quarterly (Dec. 2025) net income data. The Revenue data used here is four times the quarterly (Dec. 2025) revenue data.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.


Be Aware

Like ROE, ROA % is calculated with only 12 months data. Fluctuations in the company's earnings or business cycles can affect the ratio drastically. It is important to look at the ratio from a long term perspective. ROA % can be affected by events such as stock buyback or issuance, and by goodwill, a company's tax rate and its interest payment. ROA % may not reflect the true earning power of the assets. A more accurate measurement is ROC % (ROC).

Many analysts argue the higher return the better. Buffett states that really high ROA % may indicate vulnerability in the durability of the competitive advantage.

E.g. Raising $43b to take on KO is impossible, but $1.7b to take on Moody's is. Although Moody's ROA % and underlying economics is far superior to Coca Cola, the durability is far weaker because of lower entry cost.


Anavex Life Sciences ROA % Related Terms


Anavex Life Sciences ROA % Historical Data

* Premium members only.

The historical data trend for Anavex Life Sciences's ROA % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Anavex Life Sciences ROA % Chart

Anavex Life Sciences Annual Data
Trend Sep16 Sep17 Sep18 Sep19 Sep20 Sep21 Sep22 Sep23 Sep24 Sep25
ROA %
Get a 7-Day Free Trial Premium Member Only Premium Member Only -38.65 -30.53 -30.94 -29.66 -38.75

Anavex Life Sciences Quarterly Data
Mar21 Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25
ROA % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -37.32 -37.14 -48.25 -38.12 -19.19

AVXL vs ZNTL, HUMA, SABS: ROA % Comparison

For the Biotechnology subindustry, Anavex Life Sciences's ROA %, along with its competitors' market caps and ROA % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Anavex Life Sciences ROA % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Anavex Life Sciences's ROA % distribution charts can be found below:

* The bar in red indicates where Anavex Life Sciences's ROA % falls into.


AVXL
30GF Score
Anavex Life Sciences Corp AVXL
ROA % is just one metric. See GF Score™, valuation, warning signs, and more.
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Anavex Life Sciences ROA % Calculation

Anavex Life Sciences's annualized ROA % for the fiscal year that ended in Sep. 2025 is calculated as:

ROA %=Net Income (A: Sep. 2025 )/( (Total Assets (A: Sep. 2024 )+Total Assets (A: Sep. 2025 ))/ count )
=-46.377/( (135.567+103.815)/ 2 )
=-46.377/119.691
=-38.75 %

Anavex Life Sciences's annualized ROA % for the quarter that ended in Dec. 2025 is calculated as:

ROA %=Net Income (Q: Dec. 2025 )/( (Total Assets (Q: Sep. 2025 )+Total Assets (Q: Dec. 2025 ))/ count )
=-22.724/( (103.815+132.989)/ 2 )
=-22.724/118.402
=-19.19 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

In the calculation of annual ROA %, the net income of the last fiscal year and the average total assets over the fiscal year are used. In calculating the quarterly data, the Net Income data used here is four times the quarterly (Dec. 2025) net income data. ROA % is displayed in the 30-year financial page.

Frequently Asked Questions Learn more about ROA % →
What does a ROA % of -19.19% mean?
Anavex Life Sciences (AVXL) has a ROA % of -19.19% as of Dec. 2025. Return on assets is the ratio of current-period net income to average two-period total assets. View historical data on Anavex Life Sciences and its competitors. According to the industry distribution chart, Anavex Life Sciences ranks #735 out of 1423 companies in the Biotechnology industry, placing it in the top 51.7%.
Is Anavex Life Sciences' ROA % too high?
Anavex Life Sciences' current ROA % is -19.19%. Based on the distribution chart, Anavex Life Sciences ranks #735 out of 1423 companies in the Biotechnology industry, which is below the industry midpoint. Overall, Anavex Life Sciences has a GF Score™ of 30/100, reflecting its overall financial health beyond just this single metric.
How does Anavex Life Sciences' ROA % compare to ZNTL and HUMA?
According to the Biotechnology industry distribution chart, Anavex Life Sciences ranks #735 out of 1423 companies for ROA %. This places Anavex Life Sciences in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good ROA % for a Biotechnology company?
A good ROA % depends on the Biotechnology industry context. However, ROA % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high ROA % mean?
A high ROA % can signal that a stock is expensive relative to its fundamentals. Return on assets is the ratio of current-period net income to average two-period total assets. View historical data on Anavex Life Sciences and its competitors. Anavex Life Sciences's current ROA % is -19.19%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Anavex Life Sciences stock overvalued right now?
Anavex Life Sciences (AVXL) has a current ROA % of -19.19%. The current ROA % is -19.19%. Anavex Life Sciences' overall GF Score™ is 30/100 with 1 warning sign to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is ROA % calculated?
ROA % is calculated from a company's financial statements. For Anavex Life Sciences (AVXL), the current ROA % is -19.19% as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Anavex Life Sciences Business Description

Other Exchanges 0HFR:UK12X1:Germany
Address 630 5th Avenue, 20th Floor, New York, NY, USA, 10111
Anavex Life Sciences Corp is a clinical stage biopharmaceutical company engaged in the development of differentiated therapeutics by applying precision medicine to central nervous system(CNS) diseases with high unmet need. It analyzes genomic data from clinical trials to identify biomarkers, which are used in the analysis of its clinical trials for the treatment of neurodegenerative and neurodevelopmental diseases. The company focuses on developing treatments for Alzheimer's disease, Parkinson's disease, schizophrenia, neurodevelopmental, neurodegenerative, and rare diseases, including Rett syndrome, and other central nervous system (CNS) disorders. Its pipeline includes ANAVEX 2-73 and ANAVEX 3-71 and several other compounds in different stages of clinical and pre-clinical development.
30GF Score

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