VivoSim Labs (FRA:4OR) Cyclically Adjusted Book per Share: €139.97 (As of Dec. 2025)


FRA:4OR VivoSim Labs Inc FRA:4OR
39 GF Score
Price €3.49
GF Value €8.13
! 4 Warning Signs
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What is VivoSim Labs Cyclically Adjusted Book per Share?

VivoSim Labs FRA:4OR 39 Cyclically Adjusted Book per Share is €139.97 as of Dec. 2025. GuruFocus rates FRA:4OR with a GF Score™ of 39/100 and a GF Value™ of €8.13. The stock has 4 warning signs investors should review.

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted Book per Share and the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted Book Value per Share of a company over the past 10 years.

VivoSim Labs's adjusted book value per share for the three months ended in Dec. 2025 was €1.454. Add all the adjusted book value per share for the past 10 years together and divide the count will get our Cyclically Adjusted Book per Share, which is €139.97 for the trailing ten years ended in Dec. 2025.

During the past 12 months, VivoSim Labs's average Cyclically Adjusted Book Growth Rate was -23.60% per year. During the past 3 years, the average Cyclically Adjusted Book Growth Rate was -1.50% per year. During the past 5 years, the average Cyclically Adjusted Book Growth Rate was 6.10% per year. Please click Growth Rate Calculation Example (GuruFocus) to see how GuruFocus calculates Wal-Mart Stores Inc (WMT)'s revenue growth rate. You can apply the same method to get the Cyclically Adjusted Book Growth Rate using Cyclically Adjusted Book per Share data.

During the past 13 years, the highest 3-Year average Cyclically Adjusted Book Growth Rate of VivoSim Labs was 15.60% per year. The lowest was -1.50% per year. And the median was 11.80% per year.

As of today (2026-06-25), VivoSim Labs's current stock price is €3.492. VivoSim Labs's Cyclically Adjusted Book per Share for the quarter that ended in Dec. 2025 was €139.97. VivoSim Labs's Cyclically Adjusted PB Ratio of today is 0.02.

During the past 13 years, the highest Cyclically Adjusted PB Ratio of VivoSim Labs was 3.07. The lowest was 0.02. And the median was 0.17.


VivoSim Labs  (FRA:4OR) Cyclically Adjusted Book per Share Explanation

If a company grows much fast than inflation, Cyclically Adjusted Book per Share may underestimate the company's equity. Cyclically Adjusted PB Ratio can seem to be too high even the actual PB Ratio is low.

For the Cyclically Adjusted PB Ratio, the book value of the past 10 years are inflation-adjusted and averaged. The result is used for P/B calculation. Since it looks at the average over the last 10 years, the Cyclically Adjusted PB Ratio is also called CAPB Ratio.

The Shiller PE Ratio was first used by professor Robert Shiller. He uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings per share of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted book value per share of a company over the past 10 years.

VivoSim Labs's Cyclically Adjusted PB Ratio of today is calculated as

Cyclically Adjusted PB Ratio=Share Price/Cyclically Adjusted Book per Share
=3.492/139.97
=0.02

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

During the past 13 years, the highest Cyclically Adjusted PB Ratio of VivoSim Labs was 3.07. The lowest was 0.02. And the median was 0.17.


Be Aware

Cyclically Adjusted PB Ratio works better for cyclical companies. It gives you a better idea on the company's real book value.


VivoSim Labs Cyclically Adjusted Book per Share Related Terms


VivoSim Labs Cyclically Adjusted Book per Share Historical Data

* Premium members only.

The historical data trend for VivoSim Labs's Cyclically Adjusted Book per Share can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

VivoSim Labs Cyclically Adjusted Book per Share Chart

VivoSim Labs Annual Data
Trend Mar16 Mar17 Mar18 Mar19 Mar20 Mar21 Mar22 Mar23 Mar24 Mar25
Cyclically Adjusted Book per Share
Get a 7-Day Free Trial Premium Member Only Premium Member Only 65.14 83.63 112.58 98.12 142.69

VivoSim Labs Quarterly Data
Mar21 Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25
Cyclically Adjusted Book per Share Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 78.48 142.69 201.75 94.27 139.97

FRA:4OR vs AZTR, GRI, BIXT: Cyclically Adjusted Book per Share Comparison

For the Biotechnology subindustry, VivoSim Labs's Cyclically Adjusted PB Ratio, along with its competitors' market caps and Cyclically Adjusted PB Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


VivoSim Labs Cyclically Adjusted PB Ratio vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, VivoSim Labs's Cyclically Adjusted PB Ratio distribution charts can be found below:

* The bar in red indicates where VivoSim Labs's Cyclically Adjusted PB Ratio falls into.


FRA:4OR
39GF Score
VivoSim Labs Inc FRA:4OR
Cyclically Adjusted Book per Share is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

VivoSim Labs Cyclically Adjusted Book per Share Calculation

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted Book per Share and the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted Book Value per Share of a company over the past 10 years.

What is Cyclically Adjusted Book per Share? How do we calculate Cyclically Adjusted Book per Share?

Cyclically Adjusted Book per Share is the average of the inflation adjusted Book Value per Share of a company over the past 10 years. Let's use an example to explain.

If we want to calculate the Cyclically Adjusted Book per Share of Wal-Mart (WMT) for Dec. 31, 2010, we need to have the inflation data and the book value per share from 2001 through 2010.

We adjusted the 2001 book value per share data with the total inflation from 2001 through 2010 to the equivalent book value in 2010. If the total inflation from 2001 to 2010 is 40%, and Wal-Mart's book value is $1 a share in 2001, then the 2001's equivalent book value in 2010 is $1.4 a share. If Wal-Mart's book value is $1 again in 2002, and the total inflation from 2002 through 2010 is 35%, then the equivalent 2002 book value in 2010 is $1.35. So on and so forth, you get the equivalent book value per share of past 10 years. Then you add them together and divided the sum by the count to get Cyclically Adjusted Book per Share.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

For example, VivoSim Labs's adjusted Book Value per Share data for the three months ended in Dec. 2025 was:

Adj_Book= Book Value per Share /CPI of Dec. 2025 (Change)*Current CPI (Dec. 2025)
=1.454/324.0540*324.0540
=1.454

Current CPI (Dec. 2025) = 324.0540.

VivoSim Labs Quarterly Data

Book Value per Share CPI Adj_Book
201603 145.036 238.132 197.367
201606 126.779 241.018 170.457
201609 119.606 241.428 160.540
201612 154.878 241.432 207.880
201703 133.734 243.801 177.756
201706 115.576 244.955 152.897
201709 98.151 246.819 128.865
201712 90.061 246.524 118.385
201803 78.097 249.554 101.411
201806 75.002 251.989 96.451
201809 69.400 252.439 89.088
201812 63.866 251.233 82.378
201903 62.135 254.202 79.209
201906 58.901 256.143 74.517
201909 51.959 256.759 65.577
201912 47.903 256.974 60.408
202003 44.303 258.115 55.621
202006 40.460 257.797 50.859
202009 30.248 260.280 37.659
202012 28.766 260.474 35.788
202103 45.539 264.877 55.713
202106 42.737 271.696 50.973
202109 40.214 274.310 47.506
202112 38.199 278.802 44.399
202203 37.782 287.504 42.585
202206 36.034 296.311 39.408
202209 34.788 296.808 37.981
202212 28.982 296.797 31.644
202303 19.720 301.836 21.172
202306 14.950 305.109 15.878
202309 10.898 307.789 11.474
202312 6.913 306.746 7.303
202403 3.944 312.332 4.092
202406 5.166 314.175 5.328
202409 2.591 315.301 2.663
202412 0.244 315.605 0.251
202503 5.113 319.799 5.181
202506 3.180 322.561 3.195
202509 2.308 324.800 2.303
202512 1.454 324.054 1.454

Add all the adjusted book value per share together and divide the count will get our Cyclically Adjusted Book per Share.

What does a Cyclically Adjusted Book per Share of €139.97 mean?
VivoSim Labs (FRA:4OR) has a Cyclically Adjusted Book per Share of €139.97 as of Dec. 2025. Cyclically adjusted book value per share represents the company's inflation-adjusted book value per share over a 10-year period. View historical data on VivoSim Labs and its competitors.
Is VivoSim Labs' Cyclically Adjusted Book per Share too high?
VivoSim Labs' current Cyclically Adjusted Book per Share is €139.97. Overall, VivoSim Labs has a GF Score™ of 39/100, reflecting its overall financial health beyond just this single metric.
How does VivoSim Labs' Cyclically Adjusted Book per Share compare to AZTR and GRI?
VivoSim Labs' Cyclically Adjusted Book per Share of €139.97 can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Cyclically Adjusted Book per Share for a Biotechnology company?
A good Cyclically Adjusted Book per Share depends on the Biotechnology industry context. However, Cyclically Adjusted Book per Share should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Cyclically Adjusted Book per Share mean?
A high Cyclically Adjusted Book per Share can signal that a stock is expensive relative to its fundamentals. Cyclically adjusted book value per share represents the company's inflation-adjusted book value per share over a 10-year period. View historical data on VivoSim Labs and its competitors. VivoSim Labs's current Cyclically Adjusted Book per Share is €139.97. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is VivoSim Labs stock overvalued right now?
VivoSim Labs (FRA:4OR) has a current Cyclically Adjusted Book per Share of €139.97. The stock's GF Value™ is €8.13, compared to a current price of €3.49 — trading 57% below its estimated fair value. The current Cyclically Adjusted Book per Share is €139.97. VivoSim Labs' overall GF Score™ is 39/100 with 4 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Cyclically Adjusted Book per Share calculated?
Cyclically Adjusted Book per Share is calculated from a company's financial statements. For VivoSim Labs (FRA:4OR), the current Cyclically Adjusted Book per Share is €139.97 as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is VivoSim Labs (FRA:4OR) Overvalued in 2026?

Based on GuruFocus' analysis, VivoSim Labs stock appears to be undervalued. The current stock price of €3.49 is trading 57% below its estimated GF Value™ of €8.13.

Key valuation signals for FRA:4OR:

  • Cyclically Adjusted Book per Share: €139.97
  • GF Value™: €8.13 vs. price of €3.49 (57% below fair value)
  • GF Score™: 39/100 with 4 warning signs

No single metric tells the full story. See the FRA:4OR stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


VivoSim Labs Business Description

Other Exchanges VIVS:USA
Address 11555 Sorrento Valley road, Suite 100, San Diego, CA, USA, 92121
VivoSim Labs Inc formerly, Organovo Holdings Inc is a biotechnology company focused on developing FXR314 in inflammatory bowel disease (IBD), including ulcerative colitis (UC), based on demonstration of clinical promise in three-dimensional (3D) human tissues as well as preclinical data. FXR is a mediator of gastrointestinal and liver diseases. It is now offering liver toxicology predictive screening and research services as well as working on predicting and studying the intestinal side effect profiles of drugs that are therapeutic candidates of pharmaceutical and biotech companies at all stages of drug development.
39GF Score

Get the complete analysis for FRA:4OR

Cyclically Adjusted Book per Share is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

€3.49
Price
€8.13
GF Value