VivoSim Labs (FRA:4OR) Profitability Rank: 1 (As of Dec. 2025) — Near Median


FRA:4OR VivoSim Labs Inc FRA:4OR
39 GF Score
Price €3.49
GF Value €9.41
! 4 Warning Signs
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What is VivoSim Labs Profitability Rank?

VivoSim Labs FRA:4OR 39 Profitability Rank is 1 as of Dec. 2025, which is at its 10-year median of 1.00. GuruFocus rates FRA:4OR with a GF Score™ of 39/100 and a GF Value™ of €9.41. The stock has 4 warning signs investors should review.

VivoSim Labs has the Profitability Rank of 1. It has had trouble to make a profit.

GuruFocus Profitability Rank ranks how profitable a company is and how likely the company's business will stay that way. It is rated on a scale of 1 to 10 and is based on these factors:

1. Operating Margin %
2. Piotroski F-Score
3. Trend of the Operating Margin % (5-year average). The company with an uptrend profit margin has a higher rank.
4. Consistency of the profitability
5. Predictability Rank

A higher score indicates superior profitability, with companies rated 7 or above considered to have more robust and sustainable profit generation. Conversely, a score of 3 or lower suggests challenges in generating consistent profits.

VivoSim Labs's Operating Margin % for the quarter that ended in Dec. 2025 was -10,672.73%. As of today, VivoSim Labs's Piotroski F-Score is 5.


VivoSim Labs Profitability Rank Related Terms


FRA:4OR vs SLXN, CDT, CLDI: Profitability Rank Comparison

For the Biotechnology subindustry, VivoSim Labs's Profitability Rank, along with its competitors' market caps and Profitability Rank data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


VivoSim Labs Profitability Rank vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, VivoSim Labs's Profitability Rank distribution charts can be found below:

* The bar in red indicates where VivoSim Labs's Profitability Rank falls into.


FRA:4OR
39GF Score
VivoSim Labs Inc FRA:4OR
Profitability Rank is just one metric. See GF Score™, valuation, warning signs, and more.
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VivoSim Labs Profitability Rank Calculation

GuruFocus Profitability Rank ranks how profitable a company is and how likely the company's business will stay that way.

The rank is rated on a scale of 1 to 10. A higher score indicates superior profitability, with companies rated 7 or above considered to have more robust and sustainable profit generation. Conversely, a score of 3 or lower suggests challenges in generating consistent profits.

VivoSim Labs has the Profitability Rank of 1. It has had trouble to make a profit.

Profitability Rank is not directly related to the Financial Strength. But if a company is consistently profitable, its financial strength will be stronger.

Profitability Rank is based on these factors:

1. Operating Margin %

Operating Margin % - also known as operating income margin, operating profit margin and return on sales (ROS) - is the ratio of Operating Income divided by net sales or Revenue, usually presented in percent.

VivoSim Labs's Operating Margin % for the quarter that ended in Dec. 2025 is calculated as:

Operating Margin %=Operating Income (Q: Dec. 2025 ) / Revenue (Q: Dec. 2025 )
=-2.348 / 0.022
=-10,672.73 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

2. Piotroski F-Score

The zones of discrimination were as such:

Good or high score = 8 or 9
Bad or low score = 0 or 1

VivoSim Labs has an F-score of 5 indicating the company's financial situation is typical for a stable company.

3. Trend of the Operating Margin % (5-year average). The company with an uptrend profit margin has a higher rank.

4. Consistency of the profitability

5. Predictability Rank

Frequently Asked Questions Learn more about Profitability Rank →
What does a Profitability Rank of 1 mean?
VivoSim Labs (FRA:4OR) has a Profitability Rank of 1 as of Dec. 2025. Profitability and Growth ranks a company based on its profit margins and earnings growth. View historical data on VivoSim Labs and its competitors. This is near median its historical median of 1.00. Over the past decade, VivoSim Labs' Profitability Rank has ranged from 1.00 to 3.00.
Is VivoSim Labs' Profitability Rank too high?
VivoSim Labs' current Profitability Rank of 1 is near median its 10-year median of 1.00. Over the past 10 years, this metric has ranged from a low of 1.00 to a high of 3.00. Overall, VivoSim Labs has a GF Score™ of 39/100, reflecting its overall financial health beyond just this single metric.
How does VivoSim Labs' Profitability Rank compare to SLXN and CDT?
VivoSim Labs' Profitability Rank of 1 can be compared against companies in the Biotechnology industry. Historically, VivoSim Labs' own Profitability Rank has ranged from 1.00 to 3.00 over the past decade. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Profitability Rank for a Biotechnology company?
A good Profitability Rank depends on the Biotechnology industry context. However, Profitability Rank should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Profitability Rank mean?
A high Profitability Rank can signal that a stock is expensive relative to its fundamentals. Profitability and Growth ranks a company based on its profit margins and earnings growth. View historical data on VivoSim Labs and its competitors. VivoSim Labs's current Profitability Rank is 1, which is near median its own 10-year median of 1.00. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is VivoSim Labs stock overvalued right now?
VivoSim Labs (FRA:4OR) has a current Profitability Rank of 1. The stock's GF Value™ is €9.41, compared to a current price of €3.49 — trading 62.9% below its estimated fair value. The current Profitability Rank is 1, which is near median its 10-year median of 1.00. VivoSim Labs' overall GF Score™ is 39/100 with 4 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Profitability Rank calculated?
Profitability Rank is calculated from a company's financial statements. For VivoSim Labs (FRA:4OR), the current Profitability Rank is 1 as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is VivoSim Labs (FRA:4OR) Overvalued in 2026?

Based on GuruFocus' analysis, VivoSim Labs stock appears to be undervalued. The current stock price of €3.49 is trading 62.9% below its estimated GF Value™ of €9.41.

Key valuation signals for FRA:4OR:

  • Profitability Rank: 1 (near median its 10-year median of 1.00)
  • GF Value™: €9.41 vs. price of €3.49 (62.9% below fair value)
  • GF Score™: 39/100 with 4 warning signs

No single metric tells the full story. See the FRA:4OR stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


VivoSim Labs Business Description

Other Exchanges VIVS:USA
Address 11555 Sorrento Valley road, Suite 100, San Diego, CA, USA, 92121
VivoSim Labs Inc formerly, Organovo Holdings Inc is a biotechnology company focused on developing FXR314 in inflammatory bowel disease (IBD), including ulcerative colitis (UC), based on demonstration of clinical promise in three-dimensional (3D) human tissues as well as preclinical data. FXR is a mediator of gastrointestinal and liver diseases. It is now offering liver toxicology predictive screening and research services as well as working on predicting and studying the intestinal side effect profiles of drugs that are therapeutic candidates of pharmaceutical and biotech companies at all stages of drug development.
39GF Score

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Profitability Rank is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

€3.49
Price
€9.41
GF Value