Heron Therapeutics (FRA:AXD2) Cyclically Adjusted Book per Share: €1.52 (As of Mar. 2026)


FRA:AXD2 Heron Therapeutics Inc FRA:AXD2
49 GF Score
Price €0.35
GF Value €1.28
Valuation Possible Value Trap
! 4 Warning Signs
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What is Heron Therapeutics Cyclically Adjusted Book per Share?

Heron Therapeutics FRA:AXD2 -6.21% 49 Cyclically Adjusted Book per Share is €1.52 as of Mar. 2026. GuruFocus rates FRA:AXD2 with a GF Score™ of 49/100 and a GF Value™ of €1.28 (Possible Value Trap). The stock has 4 warning signs investors should review.

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted Book per Share and the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted Book Value per Share of a company over the past 10 years.

Heron Therapeutics's adjusted book value per share for the three months ended in Mar. 2026 was €0.037. Add all the adjusted book value per share for the past 10 years together and divide the count will get our Cyclically Adjusted Book per Share, which is €1.52 for the trailing ten years ended in Mar. 2026.

During the past 12 months, Heron Therapeutics's average Cyclically Adjusted Book Growth Rate was -18.30% per year. During the past 3 years, the average Cyclically Adjusted Book Growth Rate was -12.20% per year. During the past 5 years, the average Cyclically Adjusted Book Growth Rate was -7.20% per year. During the past 10 years, the average Cyclically Adjusted Book Growth Rate was -10.90% per year. Please click Growth Rate Calculation Example (GuruFocus) to see how GuruFocus calculates Wal-Mart Stores Inc (WMT)'s revenue growth rate. You can apply the same method to get the Cyclically Adjusted Book Growth Rate using Cyclically Adjusted Book per Share data.

During the past 13 years, the highest 3-Year average Cyclically Adjusted Book Growth Rate of Heron Therapeutics was 7.20% per year. The lowest was -42.10% per year. And the median was -6.70% per year.

As of today (2026-06-29), Heron Therapeutics's current stock price is €0.3532. Heron Therapeutics's Cyclically Adjusted Book per Share for the quarter that ended in Mar. 2026 was €1.52. Heron Therapeutics's Cyclically Adjusted PB Ratio of today is 0.23.

During the past 13 years, the highest Cyclically Adjusted PB Ratio of Heron Therapeutics was 16.34. The lowest was 0.21. And the median was 2.91.


Heron Therapeutics  (FRA:AXD2) Cyclically Adjusted Book per Share Explanation

If a company grows much fast than inflation, Cyclically Adjusted Book per Share may underestimate the company's equity. Cyclically Adjusted PB Ratio can seem to be too high even the actual PB Ratio is low.

For the Cyclically Adjusted PB Ratio, the book value of the past 10 years are inflation-adjusted and averaged. The result is used for P/B calculation. Since it looks at the average over the last 10 years, the Cyclically Adjusted PB Ratio is also called CAPB Ratio.

The Shiller PE Ratio was first used by professor Robert Shiller. He uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings per share of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted book value per share of a company over the past 10 years.

Heron Therapeutics's Cyclically Adjusted PB Ratio of today is calculated as

Cyclically Adjusted PB Ratio=Share Price/Cyclically Adjusted Book per Share
=0.3532/1.52
=0.23

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

During the past 13 years, the highest Cyclically Adjusted PB Ratio of Heron Therapeutics was 16.34. The lowest was 0.21. And the median was 2.91.


Be Aware

Cyclically Adjusted PB Ratio works better for cyclical companies. It gives you a better idea on the company's real book value.


Heron Therapeutics Cyclically Adjusted Book per Share Related Terms


Heron Therapeutics Cyclically Adjusted Book per Share Historical Data

* Premium members only.

The historical data trend for Heron Therapeutics's Cyclically Adjusted Book per Share can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Heron Therapeutics Cyclically Adjusted Book per Share Chart

Heron Therapeutics Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Cyclically Adjusted Book per Share
Get a 7-Day Free Trial Premium Member Only Premium Member Only 2.64 2.59 2.39 2.22 1.61

Heron Therapeutics Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
Cyclically Adjusted Book per Share Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 2.12 1.87 1.74 1.61 1.52

FRA:AXD2 vs ENTX, OKYO, EDSA: Cyclically Adjusted Book per Share Comparison

For the Biotechnology subindustry, Heron Therapeutics's Cyclically Adjusted PB Ratio, along with its competitors' market caps and Cyclically Adjusted PB Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Heron Therapeutics Cyclically Adjusted PB Ratio vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Heron Therapeutics's Cyclically Adjusted PB Ratio distribution charts can be found below:

* The bar in red indicates where Heron Therapeutics's Cyclically Adjusted PB Ratio falls into.


FRA:AXD2
49GF Score
Heron Therapeutics Inc FRA:AXD2
Cyclically Adjusted Book per Share is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

Heron Therapeutics Cyclically Adjusted Book per Share Calculation

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted Book per Share and the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted Book Value per Share of a company over the past 10 years.

What is Cyclically Adjusted Book per Share? How do we calculate Cyclically Adjusted Book per Share?

Cyclically Adjusted Book per Share is the average of the inflation adjusted Book Value per Share of a company over the past 10 years. Let's use an example to explain.

If we want to calculate the Cyclically Adjusted Book per Share of Wal-Mart (WMT) for Dec. 31, 2010, we need to have the inflation data and the book value per share from 2001 through 2010.

We adjusted the 2001 book value per share data with the total inflation from 2001 through 2010 to the equivalent book value in 2010. If the total inflation from 2001 to 2010 is 40%, and Wal-Mart's book value is $1 a share in 2001, then the 2001's equivalent book value in 2010 is $1.4 a share. If Wal-Mart's book value is $1 again in 2002, and the total inflation from 2002 through 2010 is 35%, then the equivalent 2002 book value in 2010 is $1.35. So on and so forth, you get the equivalent book value per share of past 10 years. Then you add them together and divided the sum by the count to get Cyclically Adjusted Book per Share.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

For example, Heron Therapeutics's adjusted Book Value per Share data for the three months ended in Mar. 2026 was:

Adj_Book= Book Value per Share /CPI of Mar. 2026 (Change)*Current CPI (Mar. 2026)
=0.037/330.2130*330.2130
=0.037

Current CPI (Mar. 2026) = 330.2130.

Heron Therapeutics Quarterly Data

Book Value per Share CPI Adj_Book
201606 1.318 241.018 1.806
201609 0.407 241.428 0.557
201612 -0.512 241.432 -0.700
201703 1.779 243.801 2.410
201706 1.136 244.955 1.531
201709 0.617 246.819 0.825
201712 1.715 246.524 2.297
201803 1.150 249.554 1.522
201806 4.754 251.989 6.230
201809 4.469 252.439 5.846
201812 4.162 251.233 5.470
201903 3.722 254.202 4.835
201906 3.387 256.143 4.366
201909 3.239 256.759 4.166
201912 4.025 256.974 5.172
202003 3.649 258.115 4.668
202006 3.169 257.797 4.059
202009 2.590 260.280 3.286
202012 2.129 260.474 2.699
202103 1.803 264.877 2.248
202106 1.304 271.696 1.585
202109 0.991 274.310 1.193
202112 0.673 278.802 0.797
202203 0.213 287.504 0.245
202206 -0.201 296.311 -0.224
202209 0.191 296.808 0.212
202212 0.108 296.797 0.120
202303 -0.089 301.836 -0.097
202306 -0.302 305.109 -0.327
202309 -0.185 307.789 -0.198
202312 -0.207 306.746 -0.223
202403 -0.207 312.332 -0.219
202406 -0.233 314.175 -0.245
202409 -0.238 315.301 -0.249
202412 -0.211 315.605 -0.221
202503 -0.173 319.799 -0.179
202506 -0.154 322.561 -0.158
202509 0.033 324.800 0.034
202512 0.060 324.054 0.061
202603 0.037 330.213 0.037

Add all the adjusted book value per share together and divide the count will get our Cyclically Adjusted Book per Share.

What does a Cyclically Adjusted Book per Share of €1.52 mean?
Heron Therapeutics (FRA:AXD2) has a Cyclically Adjusted Book per Share of €1.52 as of Mar. 2026. Cyclically adjusted book value per share represents the company's inflation-adjusted book value per share over a 10-year period. View historical data on Heron Therapeutics and its competitors.
Is Heron Therapeutics' Cyclically Adjusted Book per Share too high?
Heron Therapeutics' current Cyclically Adjusted Book per Share is €1.52. Overall, Heron Therapeutics has a GF Score™ of 49/100 and is considered Possible Value Trap, reflecting its overall financial health beyond just this single metric.
How does Heron Therapeutics' Cyclically Adjusted Book per Share compare to ENTX and OKYO?
Heron Therapeutics' Cyclically Adjusted Book per Share of €1.52 can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Cyclically Adjusted Book per Share for a Biotechnology company?
A good Cyclically Adjusted Book per Share depends on the Biotechnology industry context. However, Cyclically Adjusted Book per Share should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Cyclically Adjusted Book per Share mean?
A high Cyclically Adjusted Book per Share can signal that a stock is expensive relative to its fundamentals. Cyclically adjusted book value per share represents the company's inflation-adjusted book value per share over a 10-year period. View historical data on Heron Therapeutics and its competitors. Heron Therapeutics's current Cyclically Adjusted Book per Share is €1.52. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Heron Therapeutics stock overvalued right now?
Based on GuruFocus' analysis, Heron Therapeutics (FRA:AXD2) is currently considered Possible Value Trap. The stock's GF Value™ is €1.28, compared to a current price of €0.35 — trading 72.4% below its estimated fair value. The current Cyclically Adjusted Book per Share is €1.52. Heron Therapeutics' overall GF Score™ is 49/100 with 4 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Cyclically Adjusted Book per Share calculated?
Cyclically Adjusted Book per Share is calculated from a company's financial statements. For Heron Therapeutics (FRA:AXD2), the current Cyclically Adjusted Book per Share is €1.52 as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Heron Therapeutics (FRA:AXD2) Overvalued in 2026?

Based on GuruFocus' analysis, Heron Therapeutics stock appears to be undervalued. The current stock price of €0.35 is trading 72.4% below its estimated GF Value™ of €1.28. GuruFocus considers Heron Therapeutics to be Possible Value Trap.

Key valuation signals for FRA:AXD2:

  • Cyclically Adjusted Book per Share: €1.52
  • GF Value™: €1.28 vs. price of €0.35 (72.4% below fair value)
  • GF Score™: 49/100 with 4 warning signs

No single metric tells the full story. See the FRA:AXD2 stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Heron Therapeutics Business Description

Other Exchanges HRTX:USA0J4V:UKAXD2:Germany
Address 100 Regency Forect Drive, Suite 300, Cary, NC, USA, 27518
Heron Therapeutics Inc is a commercial-stage biotechnology company. The company is focused on improving the lives of patients by developing treatments and commercializing therapeutic solutions to address some of the unmet patient needs. The company's product portfolio consists of APONVIE, SUSTOL, ZYNRELEF, and CINVANTI.
49GF Score

Get the complete analysis for FRA:AXD2

Cyclically Adjusted Book per Share is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

€0.35
Price
€1.28
GF Value