Heron Therapeutics (FRA:AXD2) Cyclically Adjusted PS Ratio: 0.40 (As of Jul. 08, 2026) — 96% Below Median


FRA:AXD2 Heron Therapeutics Inc FRA:AXD2
47 GF Score
Price €0.37
GF Value €1.34
Valuation Possible Value Trap
! 4 Warning Signs
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What is Heron Therapeutics Cyclically Adjusted PS Ratio?

Heron Therapeutics FRA:AXD2 -1.06% 47 Cyclically Adjusted PS Ratio is 0.40 as of Jul. 08, 2026, which is 96% below its 10-year median of 10.10. GuruFocus rates FRA:AXD2 with a GF Score™ of 47/100 and a GF Value™ of €1.34 (Possible Value Trap). The stock has 4 warning signs investors should review. Among 535 Biotechnology companies, Heron Therapeutics ranks better than 91.96% on this metric.

As of today (2026-07-08), Heron Therapeutics's current share price is €0.3736. Heron Therapeutics's Cyclically Adjusted Revenue per Share for the quarter that ended in Mar. 2026 was €0.94. Heron Therapeutics's Cyclically Adjusted PS Ratio for today is 0.40.

The historical rank and industry rank for Heron Therapeutics's Cyclically Adjusted PS Ratio or its related term are showing as below:

FRA:AXD2' s Cyclically Adjusted PS Ratio Range Over the Past 10 Years
Min: 0.34   Med: 10.1   Max: 65.63
Current: 0.37

During the past years, Heron Therapeutics's highest Cyclically Adjusted PS Ratio was 65.63. The lowest was 0.34. And the median was 10.10.

FRA:AXD2's Cyclically Adjusted PS Ratio is ranked better than
91.96% of 535 companies
in the Biotechnology industry
Industry Median: 5.87 vs FRA:AXD2: 0.37

The Shiller PE Ratio was first used by professor Robert Shiller. He uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings per share of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PS Ratio. The Cyclically Adjusted Revenue per Share is the average of the inflation adjusted revenue per share of a company over the past 10 years.

Heron Therapeutics's adjusted revenue per share data for the three months ended in Mar. 2026 was €0.158. Add all the adjusted revenue per share for the past 10 years together and divide 10 will get our Cyclically Adjusted Revenue per Share, which is €0.94 for the trailing ten years ended in Mar. 2026.

Shiller PE for Stocks: The True Measure of Stock Valuation


Heron Therapeutics  (FRA:AXD2) Cyclically Adjusted PS Ratio Explanation

Compared with the regular PS Ratio, which works poorly for cyclical businesses, the Cyclically Adjusted PS Ratio smoothed out the fluctuations of revenue during business cycles. Therefore it is more accurate in reflecting the valuation of the company.

If a company has consistent business performance, the Cyclically Adjusted PS Ratio should give similar results to regular PS Ratio.


Heron Therapeutics Cyclically Adjusted PS Ratio Related Terms


Heron Therapeutics Cyclically Adjusted PS Ratio Historical Data

* Premium members only.

The historical data trend for Heron Therapeutics's Cyclically Adjusted PS Ratio can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Heron Therapeutics Cyclically Adjusted PS Ratio Chart

Heron Therapeutics Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Cyclically Adjusted PS Ratio
Get a 7-Day Free Trial Premium Member Only Premium Member Only 8.37 2.20 1.49 1.33 1.13

Heron Therapeutics Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
Cyclically Adjusted PS Ratio Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 1.91 1.79 1.09 1.13 0.69

FRA:AXD2 vs ENTX, OKYO, EDSA: Cyclically Adjusted PS Ratio Comparison

For the Biotechnology subindustry, Heron Therapeutics's Cyclically Adjusted PS Ratio, along with its competitors' market caps and Cyclically Adjusted PS Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Heron Therapeutics Cyclically Adjusted PS Ratio vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Heron Therapeutics's Cyclically Adjusted PS Ratio distribution charts can be found below:

* The bar in red indicates where Heron Therapeutics's Cyclically Adjusted PS Ratio falls into.


FRA:AXD2
47GF Score
Heron Therapeutics Inc FRA:AXD2
Cyclically Adjusted PS Ratio is just one metric. See GF Score™, valuation, warning signs, and more.
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Heron Therapeutics Cyclically Adjusted PS Ratio Calculation

Like the Shiller PE Ratio, the Cyclically Adjusted PS Ratio takes the Revenue per Share from the past 10 years, adjusts it for inflation, and then calculates the average. This average is then used for the P/S calculation. Because it considers this 10-year average, it's often referred to as the CAPS Ratio.

The Shiller PE Ratio was first used by professor Robert Shiller to measure the valuation of the overall market. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PS Ratio.

Heron Therapeutics's Cyclically Adjusted PS Ratio for today is calculated as

Cyclically Adjusted PS Ratio=Share Price/ Cyclically Adjusted Revenue per Share
=0.3736/0.94
=0.40

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Heron Therapeutics's Cyclically Adjusted Revenue per Share for the quarter that ended in Mar. 2026 is calculated as:

For example, Heron Therapeutics's adjusted Revenue per Share data for the three months ended in Mar. 2026 was:

Adj_RevenuePerShare=Revenue per Share/CPI of Mar. 2026 (Change)*Current CPI (Mar. 2026)
=0.158/330.2130*330.2130
=0.158

Current CPI (Mar. 2026) = 330.2130.

Heron Therapeutics Quarterly Data

Revenue per Share CPI Adj_RevenuePerShare
201606 0.000 241.018 0.000
201609 0.000 241.428 0.000
201612 0.031 241.432 0.042
201703 0.067 243.801 0.091
201706 0.141 244.955 0.190
201709 0.133 246.819 0.178
201712 0.147 246.524 0.197
201803 0.145 249.554 0.192
201806 0.206 251.989 0.270
201809 0.218 252.439 0.285
201812 0.324 251.233 0.426
201903 0.357 254.202 0.464
201906 0.408 256.143 0.526
201909 0.484 256.759 0.622
201912 0.354 256.974 0.455
202003 0.254 258.115 0.325
202006 0.222 257.797 0.284
202009 0.187 260.280 0.237
202012 0.186 260.474 0.236
202103 0.184 264.877 0.229
202106 0.189 271.696 0.230
202109 0.194 274.310 0.234
202112 0.179 278.802 0.212
202203 0.209 287.504 0.240
202206 0.255 296.311 0.284
202209 0.240 296.808 0.267
202212 0.238 296.797 0.265
202303 0.232 301.836 0.254
202306 0.245 305.109 0.265
202309 0.203 307.789 0.218
202312 0.207 306.746 0.223
202403 0.211 312.332 0.223
202406 0.220 314.175 0.231
202409 0.193 315.301 0.202
202412 0.254 315.605 0.266
202503 0.183 319.799 0.189
202506 0.209 322.561 0.214
202509 0.191 324.800 0.194
202512 0.184 324.054 0.187
202603 0.158 330.213 0.158

Add all the adjusted revenue per share together and divide 10 will get our Cyclically Adjusted Revenue per Share.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

What does a Cyclically Adjusted PS Ratio of 0.40 mean?
Heron Therapeutics (FRA:AXD2) has a Cyclically Adjusted PS Ratio of 0.40 as of Jul. 08, 2026. Cyclically Adjusted PS Ratio is the ratio of share price to a company's inflation-adjusted revenue per share over a 10-year period. View historical data on Heron Therapeutics and its competitors. This is 96% below median its historical median of 10.10. Over the past decade, Heron Therapeutics' Cyclically Adjusted PS Ratio has ranged from 0.34 to 65.63. According to the industry distribution chart, Heron Therapeutics ranks #43 out of 535 companies in the Biotechnology industry, placing it in the top 8%.
Is Heron Therapeutics' Cyclically Adjusted PS Ratio too high?
Heron Therapeutics' current Cyclically Adjusted PS Ratio of 0.40 is 96% below median its 10-year median of 10.10. Over the past 10 years, this metric has ranged from a low of 0.34 to a high of 65.63. The Biotechnology industry median Cyclically Adjusted PS Ratio is 5.87. Heron Therapeutics' value of 0.40 is 93.2% below this industry median. Based on the distribution chart, Heron Therapeutics ranks #43 out of 535 companies in the Biotechnology industry, which is in the top quartile — a strong position relative to peers. Overall, Heron Therapeutics has a GF Score™ of 47/100 and is considered Possible Value Trap, reflecting its overall financial health beyond just this single metric.
How does Heron Therapeutics' Cyclically Adjusted PS Ratio compare to ENTX and OKYO?
According to the Biotechnology industry distribution chart, Heron Therapeutics ranks #43 out of 535 companies for Cyclically Adjusted PS Ratio. This places Heron Therapeutics in the top 8% of its industry — outperforming the majority of peers. The industry median Cyclically Adjusted PS Ratio is 5.87. Heron Therapeutics' value of 0.40 is 93.2% below this benchmark. Historically, Heron Therapeutics' own Cyclically Adjusted PS Ratio has ranged from 0.34 to 65.63 over the past decade. While the company's 10-year median is 10.10 vs. the industry median of 5.87, Heron Therapeutics has consistently been below the industry average. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Cyclically Adjusted PS Ratio for a Biotechnology company?
The median Cyclically Adjusted PS Ratio among Biotechnology companies is 5.87, based on 535 companies in the industry. Companies in the top quartile (top 25%) have a Cyclically Adjusted PS Ratio significantly above this median, while those in the bottom quartile fall well below. However, Cyclically Adjusted PS Ratio should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Heron Therapeutics's current Cyclically Adjusted PS Ratio of 0.40 is 93.2% below the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Cyclically Adjusted PS Ratio mean?
A high Cyclically Adjusted PS Ratio can signal that a stock is expensive relative to its fundamentals. Cyclically Adjusted PS Ratio is the ratio of share price to a company's inflation-adjusted revenue per share over a 10-year period. View historical data on Heron Therapeutics and its competitors. For the Biotechnology industry, the median Cyclically Adjusted PS Ratio is 5.87 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Heron Therapeutics's current Cyclically Adjusted PS Ratio is 0.40, which is 96% below median its own 10-year median of 10.10. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Heron Therapeutics stock overvalued right now?
Based on GuruFocus' analysis, Heron Therapeutics (FRA:AXD2) is currently considered Possible Value Trap. The stock's GF Value™ is €1.34, compared to a current price of €0.37 — trading 72.1% below its estimated fair value. The current Cyclically Adjusted PS Ratio is 0.40, which is 96% below median its 10-year median of 10.10 and 93.2% below the Biotechnology industry median of 5.87. Heron Therapeutics' overall GF Score™ is 47/100 with 4 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Cyclically Adjusted PS Ratio calculated?
Cyclically Adjusted PS Ratio is calculated from a company's financial statements. For Heron Therapeutics (FRA:AXD2), the current Cyclically Adjusted PS Ratio is 0.40 as of Jul. 08, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Heron Therapeutics (FRA:AXD2) Overvalued in 2026?

Based on GuruFocus' analysis, Heron Therapeutics stock appears to be undervalued. The current stock price of €0.37 is trading 72.1% below its estimated GF Value™ of €1.34. GuruFocus considers Heron Therapeutics to be Possible Value Trap.

Key valuation signals for FRA:AXD2:

  • Cyclically Adjusted PS Ratio: 0.40 (96% below median its 10-year median of 10.10)
  • GF Value™: €1.34 vs. price of €0.37 (72.1% below fair value)
  • GF Score™: 47/100 with 4 warning signs
  • Industry Position: 93.2% below the Biotechnology median (#43 of 535)

No single metric tells the full story. See the FRA:AXD2 stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Heron Therapeutics Business Description

Other Exchanges HRTX:USA0J4V:UKAXD2:Germany
Address 100 Regency Forect Drive, Suite 300, Cary, NC, USA, 27518
Heron Therapeutics Inc is a commercial-stage biotechnology company. The company is focused on improving the lives of patients by developing treatments and commercializing therapeutic solutions to address some of the unmet patient needs. The company's product portfolio consists of APONVIE, SUSTOL, ZYNRELEF, and CINVANTI.
47GF Score

Get the complete analysis for FRA:AXD2

Cyclically Adjusted PS Ratio is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

€0.37
Price
€1.34
GF Value