BCRX (BioCryst Pharmaceuticals) Cyclically Adjusted PB Ratio: (As of Aug. 07, 2026)

Author: Vera Yuan Vera Yuan
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Director of Data and Quant Analytics at GuruFocus
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Dr. Charlie Tian is the founder and CEO of GuruFocus.com, a leading global investment research platform established in 2004. With a Ph.D. in physics, Dr. Tian transitioned from science to finance, applying a data-driven, disciplined approach to value investing.

BCRX BioCryst Pharmaceuticals Inc BCRX
69 GF Score
Price $9.31
GF Value $12.10
Valuation Modestly Undervalued
! 3 Warning Signs
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What is BioCryst Pharmaceuticals Cyclically Adjusted PB Ratio?

Shiller PE for Stocks: The True Measure of Stock Valuation


BioCryst Pharmaceuticals  (NAS:BCRX) Cyclically Adjusted PB Ratio Explanation

Compared with the regular PB Ratio, which works poorly for cyclical businesses, the Cyclically Adjusted PB Ratio smoothed out the fluctuations of book value during business cycles. Therefore it is more accurate in reflecting the valuation of the company.

If a company has consistent business performance, the Cyclically Adjusted PB Ratio should give similar results to regular PB Ratio.


BioCryst Pharmaceuticals Cyclically Adjusted PB Ratio Related Terms


BioCryst Pharmaceuticals Cyclically Adjusted PB Ratio Historical Data

* Premium members only.

The historical data trend for BioCryst Pharmaceuticals's Cyclically Adjusted PB Ratio can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

BioCryst Pharmaceuticals Cyclically Adjusted PB Ratio Chart

BioCryst Pharmaceuticals Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Cyclically Adjusted PB Ratio
Get a 7-Day Free Trial Premium Member Only Premium Member Only 41.71 57.70 902.39 0.00 0.00

BioCryst Pharmaceuticals Quarterly Data
Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26 Jun26
Cyclically Adjusted PB Ratio Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 0.00 0.00 0.00 0.00 0.00

BCRX vs PBH, SUPN, AMLX: Cyclically Adjusted PB Ratio Comparison

For the Drug Manufacturers - Specialty & Generic subindustry, BioCryst Pharmaceuticals's Cyclically Adjusted PB Ratio, along with its competitors' market caps and Cyclically Adjusted PB Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


BioCryst Pharmaceuticals Cyclically Adjusted PB Ratio vs Drug Manufacturers Industry

For the Drug Manufacturers industry and Healthcare sector, BioCryst Pharmaceuticals's Cyclically Adjusted PB Ratio distribution charts can be found below:

* The bar in red indicates where BioCryst Pharmaceuticals's Cyclically Adjusted PB Ratio falls into.


BCRX
69GF Score
BioCryst Pharmaceuticals Inc BCRX
Cyclically Adjusted PB Ratio is just one metric. See GF Score™, valuation, warning signs, and more.
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BioCryst Pharmaceuticals Cyclically Adjusted PB Ratio Calculation

Like the Shiller PE Ratio, the Cyclically Adjusted PB Ratio takes the Book Value per Share from the past 10 years, adjusts it for inflation, and then calculates the average. This average is then used for the P/B calculation. Because it considers this 10-year average, it's often referred to as the CAPB Ratio.

The Shiller PE Ratio was first used by professor Robert Shiller to measure the valuation of the overall market. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio.

BioCryst Pharmaceuticals's Cyclically Adjusted Book per Share for the quarter that ended in Jun. 2026 is calculated as:

For example, BioCryst Pharmaceuticals's adjusted Book Value per Share data for the three months ended in Jun. 2026 was:

Adj_Book=Book Value per Share/CPI of Jun. 2026 (Change)*Current CPI (Jun. 2026)
=-1.78/333.9520*333.9520
=-1.780

Current CPI (Jun. 2026) = 333.9520.

BioCryst Pharmaceuticals Quarterly Data

Book Value per Share CPI Adj_Book
201609 0.054 241.428 0.075
201612 0.021 241.432 0.029
201703 0.479 243.801 0.656
201706 0.299 244.955 0.408
201709 1.023 246.819 1.384
201712 0.851 246.524 1.153
201803 0.629 249.554 0.842
201806 0.467 251.989 0.619
201809 0.665 252.439 0.880
201812 0.447 251.233 0.594
201903 0.204 254.202 0.268
201906 -0.083 256.143 -0.108
201909 -0.374 256.759 -0.486
201912 0.248 256.974 0.322
202003 0.024 258.115 0.031
202006 0.434 257.797 0.562
202009 0.191 260.280 0.245
202012 -0.109 260.474 -0.140
202103 -0.422 264.877 -0.532
202106 -0.594 271.696 -0.730
202109 -0.818 274.310 -0.996
202112 -0.580 278.802 -0.695
202203 -0.885 287.504 -1.028
202206 -1.147 296.311 -1.293
202209 -1.302 296.808 -1.465
202212 -1.568 296.797 -1.764
202303 -1.738 301.836 -1.923
202306 -2.051 305.109 -2.245
202309 -2.165 307.789 -2.349
202312 -2.214 306.746 -2.410
202403 -2.308 312.332 -2.468
202406 -2.302 314.175 -2.447
202409 -2.262 315.301 -2.396
202412 -2.282 315.605 -2.415
202503 -2.160 319.799 -2.256
202506 -2.008 322.561 -2.079
202509 -1.843 324.800 -1.895
202512 -0.559 324.054 -0.576
202603 -2.180 330.213 -2.205
202606 -1.780 333.952 -1.780

Add all the adjusted book value per share together and divide the count will get our Cyclically Adjusted Book per Share.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

Is BioCryst Pharmaceuticals (BCRX) Overvalued in 2026?

Based on GuruFocus' analysis, BioCryst Pharmaceuticals stock appears to be undervalued. The current stock price of $9.31 is trading 23.1% below its estimated GF Value™ of $12.10. GuruFocus considers BioCryst Pharmaceuticals to be Modestly Undervalued.

Key valuation signals for BCRX:

  • Cyclically Adjusted PB Ratio:
  • GF Value™: $12.10 vs. price of $9.31 (23.1% below fair value)
  • GF Score™: 69/100 with 3 warning signs

No single metric tells the full story. See the BCRX stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


BioCryst Pharmaceuticals Business Description

Other Exchanges BCRX:MexicoBO1:Germany
Address 4505 Emperor Boulevard, Suite 200, Durham, NC, USA, 27703
BioCryst Pharmaceuticals Inc is a biotechnology company involved mainly in the research and development of novel small-molecule drugs, to block key enzymes involved in infectious and inflammatory diseases. Biocryst's research is based on multiple scientific disciplines like biology, computer modeling, and medicinal chemistry. Its products and candidates target the following therapeutic areas: acute uncomplicated influenza; uncomplicated seasonal influenza; hereditary angioedema; filoviruses, including the Ebola and Marburg viruses; and oncology.
69GF Score

Get the complete analysis for BCRX

Cyclically Adjusted PB Ratio is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$9.31
Price
$12.10
GF Value