BioCryst PharmaceuticalsBCRX +2.55%62 Piotroski F-Score is 4 as of Jun. 25, 2026, which is 33% above its 10-year median of 3.00. GuruFocus rates BCRX with a GF Score™ of 62/100 and a GF Value™ of $12.77 (Modestly Undervalued). The stock has 4 warning signs investors should review. Among 981 Drug Manufacturers companies, BioCryst Pharmaceuticals ranks worse than 60.96% on this metric.
The zones of discrimination were as such:
Good or high score = 7, 8, 9
Bad or low score = 0, 1, 2, 3
BioCryst Pharmaceuticals has an F-score of 4 indicating the company's financial situation is typical for a stable company.
The historical rank and industry rank for BioCryst Pharmaceuticals's Piotroski F-Score or its related term are showing as below:
BCRX'
s Piotroski F-Score Range Over the Past 10 Years
Min: 1 Med: 3 Max: 7
Current: 4
During the past 13 years, the highest Piotroski F-Score of BioCryst Pharmaceuticals was 7. The lowest was 1. And the median was 3.
The developer of the system is Joseph D. Piotroski is relatively unknown accounting professor who shuns publicity and rarely gives interviews.
He graduated from the University of Illinois with a B.S. in accounting in 1989, received an M.B.A. from Indiana University in 1994. Five years later, in 1999, after earning a Ph.D. in accounting from the University of Michigan, he became an associate professor of accounting at the University of Chicago.
He wanted to see if he can develop a system (using a simple nine-point scoring system) that can increase the returns of a strategy of investing in low price to book (referred to in the paper as high book to market) value companies.
What he found was something that exceeded his most optimistic expectations.
Buying only those companies that scored highest (8 or 9) on his nine-point scale, or F-Score as he called it, over the 20 year period from 1976 to 1996 led to an average out-performance over the market of 13.4%.
Even more impressive were the results of a strategy of investing in the highest F-Score companies (8 or 9) and shorting companies with the lowest F-Score (0 or 1).
Over the same period from 1976 to 1996 (20 years) this strategy led to an average yearly return of 23%, substantially outperforming the average S&P 500 index return of 15.83% over the same period.
BioCryst Pharmaceuticals Piotroski F-Score Related Terms
BioCryst Pharmaceuticals Piotroski F-Score Historical Data
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
BCRX vs PBH, SUPN, ANIP: Piotroski F-Score Comparison
For the Drug Manufacturers - Specialty & Generic subindustry, BioCryst Pharmaceuticals's Piotroski F-Score, along with its competitors' market caps and Piotroski F-Score data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
BioCryst Pharmaceuticals Piotroski F-Score vs Drug Manufacturers Industry
For the Drug Manufacturers industry and Healthcare sector, BioCryst Pharmaceuticals's Piotroski F-Score distribution charts can be found below:
* The bar in red indicates where BioCryst Pharmaceuticals's Piotroski F-Score falls into.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
*Note: If the latest quarterly/semi-annual/annual total assets data is 0, then we will use previous quarterly/semi-annual/annual data for all the items in the balance sheet.
Profitability
Question 1. Return on Assets (ROA)
Net income before extraordinary items for the year divided by Total Assets at the beginning of the year.
Score 1 if positive, 0 if negative.
BioCryst Pharmaceuticals's current Net Income (TTM) was -458.0.
==> Negative ==> Score 0.
Question 2. Cash Flow Return on Assets (CFROA)
Net cash flow from operating activities (operating cash flow) divided by Total Assets at the beginning of the year.
Score 1 if positive, 0 if negative.
BioCryst Pharmaceuticals's current Cash Flow from Operations (TTM) was 313.1.
==> Positive ==> Score 1.
Question 3. Change in Return on Assets
Compare this year's return on assets (1) to last year's return on assets.
BioCryst Pharmaceuticals's return on assets of this year was -0.95403783. BioCryst Pharmaceuticals's return on assets of last year was -0.11427851.
==> Last year is higher ==> Score 0.
Question 4. Quality of Earnings (Accrual)
Compare Cash flow return on assets (2) to return on assets (1)
BioCryst Pharmaceuticals's gearing of this year was 1.7239064. BioCryst Pharmaceuticals's gearing of last year was 1.64885189.
==> Last year is lower than this year ==> Score 0.
Question 6. Change in Working Capital (Liquidity)
Compare this year's current ratio (current assets divided by current liabilities) to last year's current ratio.
Score 1 if this year's current ratio is higher, 0 if it's lower
BioCryst Pharmaceuticals's current ratio of this year was 1.91219145. BioCryst Pharmaceuticals's current ratio of last year was 2.93144328.
==> Last year's current ratio is higher ==> Score 0.
Question 7. Change in Shares in Issue
Compare the number of shares in issue this year, to the number in issue last year.
Score 0 if there is larger number of shares in issue this year, 1 otherwise.
BioCryst Pharmaceuticals's number of shares in issue this year was 242.258. BioCryst Pharmaceuticals's number of shares in issue last year was 215.261.
==> There is larger number of shares in issue this year. ==> Score 0.
Efficiency
Question 8. Change in Gross Margin
Compare this year's gross margin (Gross Profit divided by sales) to last year's.
Score 1 if this year's gross margin is higher, 0 if it's lower.
BioCryst Pharmaceuticals's gross margin of this year was 0.97755037. BioCryst Pharmaceuticals's gross margin of last year was 0.96907157.
==> This year's gross margin is higher. ==> Score 1.
Question 9. Change in asset turnover
Compare this year's asset turnover (total sales for the year divided by total assets at the beginning of the year) to last year's asset turnover ratio.
Score 1 if this year's asset turnover ratio is higher, 0 if it's lower
BioCryst Pharmaceuticals's asset turnover of this year was 1.845061. BioCryst Pharmaceuticals's asset turnover of last year was 1.07607097.
==> This year's asset turnover is higher. ==> Score 1.
Evaluation
Piotroski F-Score
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4
Good or high score = 7, 8, 9
Bad or low score = 0, 1, 2, 3
BioCryst Pharmaceuticals has an F-score of 4 indicating the company's financial situation is typical for a stable company.
BioCryst Pharmaceuticals (BCRX) has a Piotroski F-Score of 4 as of Jun. 25, 2026. The Piotroski F-score grades a company's business operating strength from 0-9. View historical data on BioCryst Pharmaceuticals and its competitors. This is 33% above median its historical median of 3.00. Over the past decade, BioCryst Pharmaceuticals' Piotroski F-Score has ranged from 1.00 to 7.00. According to the industry distribution chart, BioCryst Pharmaceuticals ranks #598 out of 981 companies in the Drug Manufacturers industry, placing it in the top 61%.
Is BioCryst Pharmaceuticals' Piotroski F-Score too high?
BioCryst Pharmaceuticals' current Piotroski F-Score of 4 is 33% above median its 10-year median of 3.00. Over the past 10 years, this metric has ranged from a low of 1.00 to a high of 7.00. The Drug Manufacturers industry median Piotroski F-Score is 5.00. BioCryst Pharmaceuticals' value of 4 is 20% below this industry median. Based on the distribution chart, BioCryst Pharmaceuticals ranks #598 out of 981 companies in the Drug Manufacturers industry, which is below the industry midpoint. Overall, BioCryst Pharmaceuticals has a GF Score™ of 62/100 and is considered Modestly Undervalued, reflecting its overall financial health beyond just this single metric.
How does BioCryst Pharmaceuticals' Piotroski F-Score compare to PBH and SUPN?
According to the Drug Manufacturers industry distribution chart, BioCryst Pharmaceuticals ranks #598 out of 981 companies for Piotroski F-Score. This places BioCryst Pharmaceuticals in the lower half of its industry. The industry median Piotroski F-Score is 5.00. BioCryst Pharmaceuticals' value of 4 is 20% below this benchmark. Historically, BioCryst Pharmaceuticals' own Piotroski F-Score has ranged from 1.00 to 7.00 over the past decade. While the company's 10-year median is 3.00 vs. the industry median of 5.00, BioCryst Pharmaceuticals has consistently been below the industry average. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Piotroski F-Score for a Drug Manufacturers company?
The median Piotroski F-Score among Drug Manufacturers companies is 5.00, based on 981 companies in the industry. Companies in the top quartile (top 25%) have a Piotroski F-Score significantly above this median, while those in the bottom quartile fall well below. However, Piotroski F-Score should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. BioCryst Pharmaceuticals's current Piotroski F-Score of 4 is 20% below the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Piotroski F-Score mean?
A high Piotroski F-Score can signal that a stock is expensive relative to its fundamentals. The Piotroski F-score grades a company's business operating strength from 0-9. View historical data on BioCryst Pharmaceuticals and its competitors. For the Drug Manufacturers industry, the median Piotroski F-Score is 5.00 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. BioCryst Pharmaceuticals's current Piotroski F-Score is 4, which is 33% above median its own 10-year median of 3.00. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is BioCryst Pharmaceuticals stock overvalued right now?
Based on GuruFocus' analysis, BioCryst Pharmaceuticals (BCRX) is currently considered Modestly Undervalued. The stock's GF Value™ is $12.77, compared to a current price of $10.26 — trading 19.7% below its estimated fair value. The current Piotroski F-Score is 4, which is 33% above median its 10-year median of 3.00 and 20% below the Drug Manufacturers industry median of 5.00. BioCryst Pharmaceuticals' overall GF Score™ is 62/100 with 4 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Piotroski F-Score calculated?
Piotroski F-Score is calculated from a company's financial statements. For BioCryst Pharmaceuticals (BCRX), the current Piotroski F-Score is 4 as of Jun. 25, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Is BioCryst Pharmaceuticals (BCRX) Overvalued in 2026?
Based on GuruFocus' analysis, BioCryst Pharmaceuticals stock appears to be undervalued.
The current stock price of $10.26 is trading 19.7% below its estimated GF Value™ of $12.77.
GuruFocus considers BioCryst Pharmaceuticals to be Modestly Undervalued.
Key valuation signals for BCRX:
Piotroski F-Score: 4 (33% above median its 10-year median of 3.00)
GF Value™: $12.77 vs. price of $10.26 (19.7% below fair value)
Industry Position: 20% below the Drug Manufacturers median (#598 of 981)
No single metric tells the full story. See the BCRX stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.
BioCryst Pharmaceuticals Inc is a biotechnology company involved mainly in the research and development of novel small-molecule drugs, to block key enzymes involved in infectious and inflammatory diseases. Biocryst's research is based on multiple scientific disciplines like biology, computer modeling, and medicinal chemistry. Its products and candidates target the following therapeutic areas: acute uncomplicated influenza; uncomplicated seasonal influenza; hereditary angioedema; filoviruses, including the Ebola and Marburg viruses; and oncology.
62GF Score
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