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BioStem TechnologiesBSEM +0.56%49 Cyclically Adjusted PB Ratio is 31.42 as of Jul. 18, 2026, which is 48% above its 10-year median of 21.24. GuruFocus rates BSEM with a GF Score™ of 49/100 and a GF Value™ of $144.52 (Possible Value Trap). The stock has 3 warning signs investors should review. Among 697 Biotechnology companies, BioStem Technologies ranks worse than 96.84% on this metric.
The historical rank and industry rank for BioStem Technologies's Cyclically Adjusted PB Ratio or its related term are showing as below:
BSEM'
s Cyclically Adjusted PB Ratio Range Over the Past 10 Years
Min: 0.03 Med: 21.24 Max: 155
Current: 32.24
During the past 13 years, BioStem Technologies's highest Cyclically Adjusted PB Ratio was 155.00. The lowest was 0.03. And the median was 21.24.
BSEM's Cyclically Adjusted PB Ratio is ranked worse than 96.84% of 697
companies
in the Biotechnology industry
Industry Median: 1.63
vs BSEM: 32.24
The Shiller PE Ratio was first used by professor Robert Shiller. He uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings per share of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted book value per share of a company over the past 10 years.
BioStem Technologies's adjusted book value per share data of for the fiscal year that ended in Dec24 was $2.456. Add all the adjusted book value per share for the past 10 years together and divide the count will get our Cyclically Adjusted Book per Share, which is $0.12 for the trailing ten years ended in Dec24.
Shiller PE for Stocks: The True Measure of Stock Valuation
BioStem Technologies (OTCPK:BSEM) Cyclically Adjusted PB Ratio Explanation
Compared with the regular PB Ratio, which works poorly for cyclical businesses, the Cyclically Adjusted PB Ratio smoothed out the fluctuations of book value during business cycles. Therefore it is more accurate in reflecting the valuation of the company.
If a company has consistent business performance, the Cyclically Adjusted PB Ratio should give similar results to regular PB Ratio.
BioStem Technologies Cyclically Adjusted PB Ratio Related Terms
BioStem Technologies Cyclically Adjusted PB Ratio Historical Data
* Premium members only.
The historical data trend for BioStem Technologies's Cyclically Adjusted PB Ratio can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
BioStem Technologies Cyclically Adjusted PB Ratio Chart
BSEM vs XLO, TCRX, MNOV: Cyclically Adjusted PB Ratio Comparison
For the Biotechnology subindustry, BioStem Technologies's Cyclically Adjusted PB Ratio, along with its competitors' market caps and Cyclically Adjusted PB Ratio data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
BioStem Technologies Cyclically Adjusted PB Ratio vs Biotechnology Industry
For the Biotechnology industry and Healthcare sector, BioStem Technologies's Cyclically Adjusted PB Ratio distribution charts can be found below:
* The bar in red indicates where BioStem Technologies's Cyclically Adjusted PB Ratio falls into.
BioStem Technologies Cyclically Adjusted PB Ratio Calculation
Like the Shiller PE Ratio, the Cyclically Adjusted PB Ratio takes the Book Value per Share from the past 10 years, adjusts it for inflation, and then calculates the average. This average is then used for the P/B calculation. Because it considers this 10-year average, it's often referred to as the CAPB Ratio.
The Shiller PE Ratio was first used by professor Robert Shiller to measure the valuation of the overall market. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.
What does a Cyclically Adjusted PB Ratio of 31.42 mean?
BioStem Technologies (BSEM) has a Cyclically Adjusted PB Ratio of 31.42 as of Jul. 18, 2026. Cyclically Adjusted PB Ratio is the ratio of share price to a company's inflation-adjusted book value per share over a 10-year period. View historical data on BioStem Technologies and its competitors. This is 48% above median its historical median of 21.24. Over the past decade, BioStem Technologies' Cyclically Adjusted PB Ratio has ranged from 0.03 to 155.00. According to the industry distribution chart, BioStem Technologies ranks #675 out of 697 companies in the Biotechnology industry, placing it in the top 96.8%.
Is BioStem Technologies' Cyclically Adjusted PB Ratio too high?
BioStem Technologies' current Cyclically Adjusted PB Ratio of 31.42 is 48% above median its 10-year median of 21.24. Over the past 10 years, this metric has ranged from a low of 0.03 to a high of 155.00. The Biotechnology industry median Cyclically Adjusted PB Ratio is 1.63. BioStem Technologies' value of 31.42 is 1827.6% above this industry median. Based on the distribution chart, BioStem Technologies ranks #675 out of 697 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, BioStem Technologies has a GF Score™ of 49/100 and is considered Possible Value Trap, reflecting its overall financial health beyond just this single metric.
How does BioStem Technologies' Cyclically Adjusted PB Ratio compare to XLO and TCRX?
According to the Biotechnology industry distribution chart, BioStem Technologies ranks #675 out of 697 companies for Cyclically Adjusted PB Ratio. This places BioStem Technologies in the lower half of its industry. The industry median Cyclically Adjusted PB Ratio is 1.63. BioStem Technologies' value of 31.42 is 1827.6% above this benchmark. Historically, BioStem Technologies' own Cyclically Adjusted PB Ratio has ranged from 0.03 to 155.00 over the past decade. While the company's 10-year median is 21.24 vs. the industry median of 1.63, BioStem Technologies has consistently been above the industry average. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Cyclically Adjusted PB Ratio for a Biotechnology company?
The median Cyclically Adjusted PB Ratio among Biotechnology companies is 1.63, based on 697 companies in the industry. Companies in the top quartile (top 25%) have a Cyclically Adjusted PB Ratio significantly above this median, while those in the bottom quartile fall well below. However, Cyclically Adjusted PB Ratio should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. BioStem Technologies's current Cyclically Adjusted PB Ratio of 31.42 is 1827.6% above the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Cyclically Adjusted PB Ratio mean?
A high Cyclically Adjusted PB Ratio can signal that a stock is expensive relative to its fundamentals. Cyclically Adjusted PB Ratio is the ratio of share price to a company's inflation-adjusted book value per share over a 10-year period. View historical data on BioStem Technologies and its competitors. For the Biotechnology industry, the median Cyclically Adjusted PB Ratio is 1.63 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. BioStem Technologies's current Cyclically Adjusted PB Ratio is 31.42, which is 48% above median its own 10-year median of 21.24. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is BioStem Technologies stock overvalued right now?
Based on GuruFocus' analysis, BioStem Technologies (BSEM) is currently considered Possible Value Trap. The stock's GF Value™ is $144.52, compared to a current price of $3.77 — trading 97.4% below its estimated fair value. The current Cyclically Adjusted PB Ratio is 31.42, which is 48% above median its 10-year median of 21.24 and 1827.6% above the Biotechnology industry median of 1.63. BioStem Technologies' overall GF Score™ is 49/100 with 3 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Cyclically Adjusted PB Ratio calculated?
Cyclically Adjusted PB Ratio is calculated from a company's financial statements. For BioStem Technologies (BSEM), the current Cyclically Adjusted PB Ratio is 31.42 as of Jul. 18, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Is BioStem Technologies (BSEM) Overvalued in 2026?
Based on GuruFocus' analysis, BioStem Technologies stock appears to be undervalued.
The current stock price of $3.77 is trading 97.4% below its estimated GF Value™ of $144.52.
GuruFocus considers BioStem Technologies to be Possible Value Trap.
Key valuation signals for BSEM:
Cyclically Adjusted PB Ratio: 31.42 (48% above median its 10-year median of 21.24)
GF Value™: $144.52 vs. price of $3.77 (97.4% below fair value)
Industry Position: 1827.6% above the Biotechnology median (#675 of 697)
No single metric tells the full story. See the BSEM stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.
BioStem Technologies Inc is a regenerative biotechnology company focused on harnessing elements of perinatal tissue and the body's innate biology to repair or reverse damage caused by a broad range of degenerative diseases. The company develops, manufactures, and sells tissue allografts for the wound care market with a focus on the treatment of diabetic, pressure, and venous ulcers. Utilizing its proprietary BioRetain processing method, it manufactures perinatal tissue allografts. The company offers a comprehensive portfolio of high-quality brands that are trademarked and include VENDAJE AC, AmnioWrap2, and Others. The company generates key revenue from VENDAJE AC.
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