BSEM (BioStem Technologies) Operating Margin %: 13.84% (As of Sep. 2025)


BSEM BioStem Technologies Inc BSEM
49 GF Score
Price $3.50
GF Value $139.96
Valuation Possible Value Trap
! 3 Warning Signs
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What is BioStem Technologies Operating Margin %?

BioStem Technologies BSEM +1.74% 49 Operating Margin % is 13.84% as of Sep. 2025. GuruFocus rates BSEM with a GF Score™ of 49/100 and a GF Value™ of $139.96 (Possible Value Trap). The stock has 3 warning signs investors should review. Among 944 Biotechnology companies, BioStem Technologies ranks better than 74.68% on this metric.

Operating Margin % is calculated as Operating Income divided by its Revenue. BioStem Technologies's Operating Income for the three months ended in Sep. 2025 was $1.4 Mil. BioStem Technologies's Revenue for the three months ended in Sep. 2025 was $10.5 Mil. Therefore, BioStem Technologies's Operating Margin % for the quarter that ended in Sep. 2025 was 13.84%.

The historical rank and industry rank for BioStem Technologies's Operating Margin % or its related term are showing as below:

BSEM' s Operating Margin % Range Over the Past 10 Years
Min: -1553.29   Med: -142.06   Max: 10.34
Current: 3.74


BSEM's Operating Margin % is ranked better than
74.68% of 944 companies
in the Biotechnology industry
Industry Median: -86.83 vs BSEM: 3.74

BioStem Technologies's 5-Year Average Operating Margin % Growth Rate was 0.00% per year.

BioStem Technologies's Operating Income for the three months ended in Sep. 2025 was $1.4 Mil. Its Operating Income for the trailing twelve months (TTM) ended in Sep. 2025 was $9.9 Mil.


BioStem Technologies  (OTCPK:BSEM) Operating Margin % Explanation

Just like Gross Margin %, it is important to see a company maintains its operating margin over time. Among the same industry, a company with higher operating margin is more efficient in its operation. It is also more stable during industry slowdown or recessions. Peter Lynch prefers those with higher margins than those with lower margins.


Be Aware

Operating Margin % can be manipulated by adjusting the rate of depreciation, depletion and amortization (DDA).

If a company is facing competition, its Operating Margin % may decline. Often the Operating Margin % declines well before the company's Revenue or even profit decline. Therefore, Operating Margin % is a very important indicator of whether the company is facing problems.

For instance, by 2012, Nokia (NOK)'s problems were well known and its stock had lost more than 90% of its market value since 2007. But Nokia’s Operating Margin % had already been in decline since 2002, although its Earnings per Share (Diluted) were still rising. Investors who paid attention to Operating Margin % would have avoided this huge loss. The same can be said for Research-in-Motion (RIMM).

Therefore, Operating Margin % is a very important screening filter for GuruFocus. GuruFocus's Buffett-Munger screener requires that the profit margin is either consistent or expanding. The Model Portfolio of the Buffett-Munger screener has outperformed the market every year since inception in 2009.


BioStem Technologies Operating Margin % Related Terms


BioStem Technologies Operating Margin % Historical Data

* Premium members only.

The historical data trend for BioStem Technologies's Operating Margin % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

BioStem Technologies Operating Margin % Chart

BioStem Technologies Annual Data
Trend Dec15 Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24
Operating Margin %
Get a 7-Day Free Trial Premium Member Only Premium Member Only -67.70 -37.00 -68.10 -46.62 10.34

BioStem Technologies Quarterly Data
Mar19 Jun19 Sep19 Dec19 Mar20 Jun20 Sep20 Dec20 Mar21 Sep21 Dec21 Mar22 Sep22 Dec22 Mar23 Sep23 Dec23 Sep24 Dec24 Sep25
Operating Margin % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -38.23 -2.30 50.46 3.33 13.84

BSEM vs TCRX, BYSI, MCRB: Operating Margin % Comparison

For the Biotechnology subindustry, BioStem Technologies's Operating Margin %, along with its competitors' market caps and Operating Margin % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


BioStem Technologies Operating Margin % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, BioStem Technologies's Operating Margin % distribution charts can be found below:

* The bar in red indicates where BioStem Technologies's Operating Margin % falls into.


BSEM
49GF Score
BioStem Technologies Inc BSEM
Operating Margin % is just one metric. See GF Score™, valuation, warning signs, and more.
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BioStem Technologies Operating Margin % Calculation

Operating Margin % - also known as operating income margin, operating profit margin and return on sales (ROS) - is the ratio of Operating Income divided by net sales or Revenue, usually presented in percent.

BioStem Technologies's Operating Margin % for the fiscal year that ended in Dec. 2024 is calculated as

Operating Margin %=Operating Income (A: Dec. 2024 ) / Revenue (A: Dec. 2024 )
=31.201 / 301.827
=10.34 %

BioStem Technologies's Operating Margin % for the quarter that ended in Sep. 2025 is calculated as

Operating Margin %=Operating Income (Q: Sep. 2025 ) / Revenue (Q: Sep. 2025 )
=1.449 / 10.473
=13.84 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about Operating Margin % →
What does a Operating Margin % of 13.84% mean?
BioStem Technologies (BSEM) has a Operating Margin % of 13.84% as of Sep. 2025. Operating margin is the ratio of total operating income to net sales. View historical data on BioStem Technologies and its competitors. According to the industry distribution chart, BioStem Technologies ranks #239 out of 944 companies in the Biotechnology industry, placing it in the top 25.3%.
Is BioStem Technologies' Operating Margin % too high?
BioStem Technologies' current Operating Margin % is 13.84%. Based on the distribution chart, BioStem Technologies ranks #239 out of 944 companies in the Biotechnology industry, which is above the industry midpoint. Overall, BioStem Technologies has a GF Score™ of 49/100 and is considered Possible Value Trap, reflecting its overall financial health beyond just this single metric.
How does BioStem Technologies' Operating Margin % compare to TCRX and BYSI?
According to the Biotechnology industry distribution chart, BioStem Technologies ranks #239 out of 944 companies for Operating Margin %. This puts BioStem Technologies in the upper half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Operating Margin % for a Biotechnology company?
A good Operating Margin % depends on the Biotechnology industry context. However, Operating Margin % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Operating Margin % mean?
A high Operating Margin % can signal that a stock is expensive relative to its fundamentals. Operating margin is the ratio of total operating income to net sales. View historical data on BioStem Technologies and its competitors. BioStem Technologies's current Operating Margin % is 13.84%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is BioStem Technologies stock overvalued right now?
Based on GuruFocus' analysis, BioStem Technologies (BSEM) is currently considered Possible Value Trap. The stock's GF Value™ is $139.96, compared to a current price of $3.50 — trading 97.5% below its estimated fair value. The current Operating Margin % is 13.84%. BioStem Technologies' overall GF Score™ is 49/100 with 3 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Operating Margin % calculated?
Operating Margin % is calculated from a company's financial statements. For BioStem Technologies (BSEM), the current Operating Margin % is 13.84% as of Sep. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is BioStem Technologies (BSEM) Overvalued in 2026?

Based on GuruFocus' analysis, BioStem Technologies stock appears to be undervalued. The current stock price of $3.50 is trading 97.5% below its estimated GF Value™ of $139.96. GuruFocus considers BioStem Technologies to be Possible Value Trap.

Key valuation signals for BSEM:

  • Operating Margin %: 13.84%
  • GF Value™: $139.96 vs. price of $3.50 (97.5% below fair value)
  • GF Score™: 49/100 with 3 warning signs

No single metric tells the full story. See the BSEM stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


BioStem Technologies Business Description

Address 2836 Center Port Circle, Pompano Beach, FL, USA, 33064
BioStem Technologies Inc is a regenerative biotechnology company focused on harnessing elements of perinatal tissue and the body's innate biology to repair or reverse damage caused by a broad range of degenerative diseases. The company develops, manufactures, and sells tissue allografts for the wound care market with a focus on the treatment of diabetic, pressure, and venous ulcers. Utilizing its proprietary BioRetain processing method, it manufactures perinatal tissue allografts. The company offers a comprehensive portfolio of high-quality brands that are trademarked and include VENDAJE AC, AmnioWrap2, and Others. The company generates key revenue from VENDAJE AC.
49GF Score

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Operating Margin % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$3.50
Price
$139.96
GF Value