BSEM (BioStem Technologies) ROE %: 6.70% (As of Sep. 2025)


BSEM BioStem Technologies Inc BSEM
49 GF Score
Price $3.55
GF Value $139.96
Valuation Possible Value Trap
! 3 Warning Signs
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What is BioStem Technologies ROE %?

BioStem Technologies BSEM +3.20% 49 ROE % is 6.70% as of Sep. 2025. GuruFocus rates BSEM with a GF Score™ of 49/100 and a GF Value™ of $139.96 (Possible Value Trap). The stock has 3 warning signs investors should review. Among 1,255 Biotechnology companies, BioStem Technologies ranks better than 95.86% on this metric.

ROE % is calculated as Net Income divided by its average Total Stockholders Equity over a certain period of time. BioStem Technologies's annualized net income for the quarter that ended in Sep. 2025 was $3.0 Mil. BioStem Technologies's average Total Stockholders Equity over the quarter that ended in Sep. 2025 was $45.4 Mil. Therefore, BioStem Technologies's annualized ROE % for the quarter that ended in Sep. 2025 was 6.70%.

The historical rank and industry rank for BioStem Technologies's ROE % or its related term are showing as below:

BSEM' s ROE % Range Over the Past 10 Years
Min: -534.93   Med: -240.03   Max: 161.31
Current: 42.95

During the past 13 years, BioStem Technologies's highest ROE % was 161.31%. The lowest was -534.93%. And the median was -240.03%.

BSEM's ROE % is ranked better than
95.86% of 1255 companies
in the Biotechnology industry
Industry Median: -38.18 vs BSEM: 42.95

BioStem Technologies  (OTCPK:BSEM) ROE % Explanation

ROE % measures the rate of return on the ownership interest (shareholder's equity) of the common stock owners. It measures a firm's efficiency at generating profits from every unit of shareholders' equity (also known as net assets or assets minus liabilities). ROE % shows how well a company uses investment funds to generate earnings growth. ROE %s between 15% and 20% are considered desirable.

The factors that affect a company's ROE % can be illustrated with the three-step DuPont Analysis:

ROE %(Q: Sep. 2025 )
=Net Income/Total Stockholders Equity
=3.044/45.446
=(Net Income / Revenue )*(Revenue / Total Assets)*(Total Assets / Total Stockholders Equity)
=(3.044 / 41.892)*(41.892 / 101.3845)*(101.3845 / 45.446)
=Net Margin %*Asset Turnover*Equity Multiplier
=7.27 %*0.4132*2.2309
=ROA %*Equity Multiplier
=3 %*2.2309
=6.70 %

With this breakdown, it is clear that if a company grows its Net Profit Margin, its Asset Turnover, or its Leverage, it can grow its ROE %.

The factors that affect a company's ROE % can also be illustrated with the five-step DuPont Analysis:

ROE %(Q: Sep. 2025 )
=Net Income/Total Stockholders Equity
=3.044/45.446
=(Net Income / Pre-Tax Income) * (Pre-Tax Income / Operating Income) * (Operating Income / Revenue) * (Revenue / Total Assets) * (Total Assets / Total Stockholders Equity)
= (3.044 / 5.876) * (5.876 / 5.796) * (5.796 / 41.892) * (41.892 / 101.3845) * (101.3845 / 45.446)
= Tax Burden * Interest Burden * Operating Margin % * Asset Turnover * Equity Multiplier
= 0.518 * 1.0138 * 13.84 % * 0.4132 * 2.2309
=6.70 %

Note: The net income data used here is four times the quarterly (Sep. 2025) net income data. The Revenue data used here is four times the quarterly (Sep. 2025) revenue data. The same rule applies to Pre-Tax Income and Operating Income.
* In the five-step DuPont Analysis, Operating Income is only available for non-financial companies. Thus, for Insurance companies, we use EBIT as a substitution of Operating Income. For Banks, both Operating Income and EBIT is unavailable. Thus we combined Interest Burden and Operating Margin % into Pretax Margin %, and the DuPont Analysis is divided into four components instead.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.


Be Aware

Net Income is used.

Because a company can increase its ROE % by having more financial leverage, it is important to watch the equity multiplier when investing in high ROE % companies. Like ROA %, ROE % is calculated with only 12 months data. Fluctuations in company's earnings or business cycles can affect the ratio drastically. It is important to look at the ratio from a long term perspective.

Asset light businesses require very few assets to generate very high earnings. Their ROE %s can be extremely high.


BioStem Technologies ROE % Related Terms


BioStem Technologies ROE % Historical Data

* Premium members only.

The historical data trend for BioStem Technologies's ROE % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

BioStem Technologies ROE % Chart

BioStem Technologies Annual Data
Trend Dec15 Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24
ROE %
Get a 7-Day Free Trial Premium Member Only Premium Member Only 0.00 0.00 0.00 0.00 161.31

BioStem Technologies Quarterly Data
Mar19 Jun19 Sep19 Dec19 Mar20 Jun20 Sep20 Dec20 Mar21 Sep21 Dec21 Mar22 Sep22 Dec22 Mar23 Sep23 Dec23 Sep24 Dec24 Sep25
ROE % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 0.00 0.00 253.92 194.89 6.70

BSEM vs TCRX, BYSI, MCRB: ROE % Comparison

For the Biotechnology subindustry, BioStem Technologies's ROE %, along with its competitors' market caps and ROE % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


BioStem Technologies ROE % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, BioStem Technologies's ROE % distribution charts can be found below:

* The bar in red indicates where BioStem Technologies's ROE % falls into.


BSEM
49GF Score
BioStem Technologies Inc BSEM
ROE % is just one metric. See GF Score™, valuation, warning signs, and more.
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BioStem Technologies ROE % Calculation

BioStem Technologies's annualized ROE % for the fiscal year that ended in Dec. 2024 is calculated as

ROE %=Net Income (A: Dec. 2024 )/( (Total Stockholders Equity (A: Dec. 2023 )+Total Stockholders Equity (A: Dec. 2024 ))/ count )
=31.884/( (-1.344+40.876)/ 2 )
=31.884/19.766
=161.31 %

BioStem Technologies's annualized ROE % for the quarter that ended in Sep. 2025 is calculated as

ROE %=Net Income (Q: Sep. 2025 )/( (Total Stockholders Equity (Q: Dec. 2024 )+Total Stockholders Equity (Q: Sep. 2025 ))/ count )
=3.044/( (40.876+50.016)/ 2 )
=3.044/45.446
=6.70 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

In the calculation of annual ROE %, the net income of the last fiscal year and the average total shareholder equity over the fiscal year are used. In calculating the quarterly data, the net income data used here is four times the quarterly (Sep. 2025) net income data. ROE % is displayed in the 30-year financial page.

Frequently Asked Questions Learn more about ROE % →
What does a ROE % of 6.70% mean?
BioStem Technologies (BSEM) has a ROE % of 6.70% as of Sep. 2025. Return on equity is the ratio of current-period net income to average two-period total equity. View historical data on BioStem Technologies and its competitors. According to the industry distribution chart, BioStem Technologies ranks #52 out of 1255 companies in the Biotechnology industry, placing it in the top 4.1%.
Is BioStem Technologies' ROE % too high?
BioStem Technologies' current ROE % is 6.70%. Based on the distribution chart, BioStem Technologies ranks #52 out of 1255 companies in the Biotechnology industry, which is in the top quartile — a strong position relative to peers. Overall, BioStem Technologies has a GF Score™ of 49/100 and is considered Possible Value Trap, reflecting its overall financial health beyond just this single metric.
How does BioStem Technologies' ROE % compare to TCRX and BYSI?
According to the Biotechnology industry distribution chart, BioStem Technologies ranks #52 out of 1255 companies for ROE %. This places BioStem Technologies in the top 4% of its industry — outperforming the majority of peers. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good ROE % for a Biotechnology company?
A good ROE % depends on the Biotechnology industry context. However, ROE % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high ROE % mean?
A high ROE % can signal that a stock is expensive relative to its fundamentals. Return on equity is the ratio of current-period net income to average two-period total equity. View historical data on BioStem Technologies and its competitors. BioStem Technologies's current ROE % is 6.70%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is BioStem Technologies stock overvalued right now?
Based on GuruFocus' analysis, BioStem Technologies (BSEM) is currently considered Possible Value Trap. The stock's GF Value™ is $139.96, compared to a current price of $3.55 — trading 97.5% below its estimated fair value. The current ROE % is 6.70%. BioStem Technologies' overall GF Score™ is 49/100 with 3 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is ROE % calculated?
ROE % is calculated from a company's financial statements. For BioStem Technologies (BSEM), the current ROE % is 6.70% as of Sep. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is BioStem Technologies (BSEM) Overvalued in 2026?

Based on GuruFocus' analysis, BioStem Technologies stock appears to be undervalued. The current stock price of $3.55 is trading 97.5% below its estimated GF Value™ of $139.96. GuruFocus considers BioStem Technologies to be Possible Value Trap.

Key valuation signals for BSEM:

  • ROE %: 6.70%
  • GF Value™: $139.96 vs. price of $3.55 (97.5% below fair value)
  • GF Score™: 49/100 with 3 warning signs

No single metric tells the full story. See the BSEM stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


BioStem Technologies Business Description

Address 2836 Center Port Circle, Pompano Beach, FL, USA, 33064
BioStem Technologies Inc is a regenerative biotechnology company focused on harnessing elements of perinatal tissue and the body's innate biology to repair or reverse damage caused by a broad range of degenerative diseases. The company develops, manufactures, and sells tissue allografts for the wound care market with a focus on the treatment of diabetic, pressure, and venous ulcers. Utilizing its proprietary BioRetain processing method, it manufactures perinatal tissue allografts. The company offers a comprehensive portfolio of high-quality brands that are trademarked and include VENDAJE AC, AmnioWrap2, and Others. The company generates key revenue from VENDAJE AC.
49GF Score

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ROE % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$3.55
Price
$139.96
GF Value