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Milestone ScientificMLSS -10.47%37 Cyclically Adjusted PB Ratio is 2.91 as of Aug. 16, 2026, which is 12% below its 10-year median of 3.30. GuruFocus rates MLSS with a GF Score™ of 37/100 and a GF Value™ of $0.60 (Modestly Undervalued). The stock has 3 warning signs investors should review. Among 519 Medical Devices & Instruments companies, Milestone Scientific ranks worse than 63.58% on this metric.
The historical rank and industry rank for Milestone Scientific's Cyclically Adjusted PB Ratio or its related term are showing as below:
MLSS'
s Cyclically Adjusted PB Ratio Range Over the Past 10 Years
Min: 1.07 Med: 3.3 Max: 16.29
Current: 2.84
During the past years, Milestone Scientific's highest Cyclically Adjusted PB Ratio was 16.29. The lowest was 1.07. And the median was 3.30.
MLSS's Cyclically Adjusted PB Ratio is ranked worse than 63.58% of 519
companies
in the Medical Devices & Instruments industry
Industry Median: 1.9
vs MLSS: 2.84
The Shiller PE Ratio was first used by professor Robert Shiller. He uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings per share of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted book value per share of a company over the past 10 years.
Milestone Scientific's adjusted book value per share data for the three months ended in Jun. 2026 was $0.039. Add all the adjusted book value per share for the past 10 years together and divide the count will get our Cyclically Adjusted Book per Share, which is $0.17 for the trailing ten years ended in Jun. 2026.
Shiller PE for Stocks: The True Measure of Stock Valuation
Milestone Scientific (AMEX:MLSS) Cyclically Adjusted PB Ratio Explanation
Compared with the regular PB Ratio, which works poorly for cyclical businesses, the Cyclically Adjusted PB Ratio smoothed out the fluctuations of book value during business cycles. Therefore it is more accurate in reflecting the valuation of the company.
If a company has consistent business performance, the Cyclically Adjusted PB Ratio should give similar results to regular PB Ratio.
Milestone Scientific Cyclically Adjusted PB Ratio Related Terms
Milestone Scientific Cyclically Adjusted PB Ratio Historical Data
* Premium members only.
The historical data trend for Milestone Scientific's Cyclically Adjusted PB Ratio can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Milestone Scientific Cyclically Adjusted PB Ratio Chart
MLSS vs NEPH, HBIO, POCI: Cyclically Adjusted PB Ratio Comparison
For the Medical Instruments & Supplies subindustry, Milestone Scientific's Cyclically Adjusted PB Ratio, along with its competitors' market caps and Cyclically Adjusted PB Ratio data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
Milestone Scientific Cyclically Adjusted PB Ratio vs Medical Devices & Instruments Industry
For the Medical Devices & Instruments industry and Healthcare sector, Milestone Scientific's Cyclically Adjusted PB Ratio distribution charts can be found below:
* The bar in red indicates where Milestone Scientific's Cyclically Adjusted PB Ratio falls into.
Milestone Scientific Cyclically Adjusted PB Ratio Calculation
Like the Shiller PE Ratio, the Cyclically Adjusted PB Ratio takes the Book Value per Share from the past 10 years, adjusts it for inflation, and then calculates the average. This average is then used for the P/B calculation. Because it considers this 10-year average, it's often referred to as the CAPB Ratio.
The Shiller PE Ratio was first used by professor Robert Shiller to measure the valuation of the overall market. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.
What does a Cyclically Adjusted PB Ratio of 2.91 mean?
Milestone Scientific (MLSS) has a Cyclically Adjusted PB Ratio of 2.91 as of Aug. 16, 2026. Cyclically Adjusted PB Ratio is the ratio of share price to a company's inflation-adjusted book value per share over a 10-year period. View historical data on Milestone Scientific and its competitors. This is 12% below median its historical median of 3.30. Over the past decade, Milestone Scientific's Cyclically Adjusted PB Ratio has ranged from 1.07 to 16.29. According to the industry distribution chart, Milestone Scientific ranks #330 out of 519 companies in the Medical Devices & Instruments industry, placing it in the top 63.6%.
Is Milestone Scientific's Cyclically Adjusted PB Ratio too high?
Milestone Scientific's current Cyclically Adjusted PB Ratio of 2.91 is 12% below median its 10-year median of 3.30. Over the past 10 years, this metric has ranged from a low of 1.07 to a high of 16.29. The Medical Devices & Instruments industry median Cyclically Adjusted PB Ratio is 1.90. Milestone Scientific's value of 2.91 is 53.2% above this industry median. Based on the distribution chart, Milestone Scientific ranks #330 out of 519 companies in the Medical Devices & Instruments industry, which is below the industry midpoint. Overall, Milestone Scientific has a GF Score™ of 37/100 and is considered Modestly Undervalued, reflecting its overall financial health beyond just this single metric.
How does Milestone Scientific's Cyclically Adjusted PB Ratio compare to NEPH and HBIO?
According to the Medical Devices & Instruments industry distribution chart, Milestone Scientific ranks #330 out of 519 companies for Cyclically Adjusted PB Ratio. This places Milestone Scientific in the lower half of its industry. The industry median Cyclically Adjusted PB Ratio is 1.90. Milestone Scientific's value of 2.91 is 53.2% above this benchmark. Historically, Milestone Scientific's own Cyclically Adjusted PB Ratio has ranged from 1.07 to 16.29 over the past decade. While the company's 10-year median is 3.30 vs. the industry median of 1.90, Milestone Scientific has consistently been above the industry average. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Cyclically Adjusted PB Ratio for a Medical Devices & Instruments company?
The median Cyclically Adjusted PB Ratio among Medical Devices & Instruments companies is 1.90, based on 519 companies in the industry. Companies in the top quartile (top 25%) have a Cyclically Adjusted PB Ratio significantly above this median, while those in the bottom quartile fall well below. However, Cyclically Adjusted PB Ratio should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Milestone Scientific's current Cyclically Adjusted PB Ratio of 2.91 is 53.2% above the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Cyclically Adjusted PB Ratio mean?
A high Cyclically Adjusted PB Ratio can signal that a stock is expensive relative to its fundamentals. Cyclically Adjusted PB Ratio is the ratio of share price to a company's inflation-adjusted book value per share over a 10-year period. View historical data on Milestone Scientific and its competitors. For the Medical Devices & Instruments industry, the median Cyclically Adjusted PB Ratio is 1.90 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Milestone Scientific's current Cyclically Adjusted PB Ratio is 2.91, which is 12% below median its own 10-year median of 3.30. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Milestone Scientific stock overvalued right now?
Based on GuruFocus' analysis, Milestone Scientific (MLSS) is currently considered Modestly Undervalued. The stock's GF Value™ is $0.60, compared to a current price of $0.50 — trading 17.5% below its estimated fair value. The current Cyclically Adjusted PB Ratio is 2.91, which is 12% below median its 10-year median of 3.30 and 53.2% above the Medical Devices & Instruments industry median of 1.90. Milestone Scientific's overall GF Score™ is 37/100 with 3 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Cyclically Adjusted PB Ratio calculated?
Cyclically Adjusted PB Ratio is calculated from a company's financial statements. For Milestone Scientific (MLSS), the current Cyclically Adjusted PB Ratio is 2.91 as of Aug. 16, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Is Milestone Scientific (MLSS) Overvalued in 2026?
Based on GuruFocus' analysis, Milestone Scientific stock appears to be undervalued.
The current stock price of $0.50 is trading 17.5% below its estimated GF Value™ of $0.60.
GuruFocus considers Milestone Scientific to be Modestly Undervalued.
Key valuation signals for MLSS:
Cyclically Adjusted PB Ratio: 2.91 (12% below median its 10-year median of 3.30)
GF Value™: $0.60 vs. price of $0.50 (17.5% below fair value)
Industry Position: 53.2% above the Medical Devices & Instruments median (#330 of 519)
No single metric tells the full story. See the MLSS stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.
Milestone Scientific Inc develops and commercializes proprietary computer-controlled drug delivery systems designed to enhance the safety, precision, and patient experience associated with subcutaneous injections and fluid aspiration procedures. The company's core technology platform, Dynamic Pressure Sensing (DPS) Technology, controls flow rate and measures pressure at the needle tip in real time. DPS Technology is incorporated into both the company's dental and medical products and supports clinical applications, including local anesthesia delivery, epidural space identification in regional anesthesia procedures, and intra-articular joint injections. It operates in two segments: Dental, which markets and sells its dental products, and Medical, markets and sells its medical products.
37GF Score
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