Focused on building reliable datasets, financial models, and research tools for value-minded investors. Committed to turning complex data into practical guidance for value-investing and long-term wealth.
Dr. Charlie Tian is the founder and CEO of GuruFocus.com, a leading global investment research platform established in 2004. With a Ph.D. in physics, Dr. Tian transitioned from science to finance, applying a data-driven, disciplined approach to value investing.
Milestone ScientificMLSS -10.47%37 PB Ratio is 12.69 as of Aug. 16, 2026, which is 69% above its 10-year median of 7.50. GuruFocus rates MLSS with a GF Score™ of 37/100 and a GF Value™ of $0.60 (Modestly Undervalued). The stock has 3 warning signs investors should review. Among 782 Medical Devices & Instruments companies, Milestone Scientific ranks worse than 93.61% on this metric.
The historical rank and industry rank for Milestone Scientific's PB Ratio or its related term are showing as below:
MLSS'
s PB Ratio Range Over the Past 10 Years
Min: 2.73 Med: 7.5 Max: 255.45
Current: 12.69
During the past 13 years, Milestone Scientific's highest PB Ratio was 255.45. The lowest was 2.73. And the median was 7.50.
MLSS's PB Ratio is ranked worse than 93.61% of 782
companies
in the Medical Devices & Instruments industry
Industry Median: 2.145
vs MLSS: 12.69
During the past 12 months, Milestone Scientific's average Book Value Per Share Growth Rate was -9.30% per year.
During the past 3 years, the average Book Value Per Share Growth Rate was -38.20% per year.
During the past 5 years, the average Book Value Per Share Growth Rate was -32.40% per year.
During the past 10 years, the average Book Value Per Share Growth Rate was -13.70% per year.
During the past 13 years, the highest 3-Year average Book Value Per Share Growth Rate of Milestone Scientific was 76.30% per year. The lowest was -54.10% per year. And the median was -13.20% per year.
The PB Ratio works the best for the businesses that earn most of their profit from their assets, e.g. banks and insurance companies.
Be Aware
Some businesses have very light assets, such as software companies or insurance agencies. The PB Ratio does not work well for these companies. Some companies even have negative equity, so the PB Ratio cannot be applied to them.
Milestone Scientific PB Ratio Related Terms
Milestone Scientific PB Ratio Historical Data
* Premium members only.
The historical data trend for Milestone Scientific's PB Ratio can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
For the Medical Instruments & Supplies subindustry, Milestone Scientific's PB Ratio, along with its competitors' market caps and PB Ratio data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
Milestone Scientific PB Ratio vs Medical Devices & Instruments Industry
For the Medical Devices & Instruments industry and Healthcare sector, Milestone Scientific's PB Ratio distribution charts can be found below:
* The bar in red indicates where Milestone Scientific's PB Ratio falls into.
The PB Ratio, or Price-to-Book ratio, or Price/Book, is a financial ratio used to compare a company's market price to its Book Value per Share. It is a ratio widely used to value stocks.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
It can also be calculated from the numbers for the whole company:
A closely related ratio is called Price-to-Tangible-Book. The difference between Price-to-Tangible-Book and PB Ratio is that book value other than intangibles are used in the calculation.
Milestone Scientific (MLSS) has a PB Ratio of 12.69 as of Aug. 16, 2026. Price-to-Book ratio is the ratio of share price to a company's book value per share. View historical data on Milestone Scientific and its competitors. This is 69% above median its historical median of 7.50. Over the past decade, Milestone Scientific's PB Ratio has ranged from 2.73 to 255.45. According to the industry distribution chart, Milestone Scientific ranks #732 out of 782 companies in the Medical Devices & Instruments industry, placing it in the top 93.6%.
Is Milestone Scientific's PB Ratio too high?
Milestone Scientific's current PB Ratio of 12.69 is 69% above median its 10-year median of 7.50. Over the past 10 years, this metric has ranged from a low of 2.73 to a high of 255.45. The Medical Devices & Instruments industry median PB Ratio is 2.15. Milestone Scientific's value of 12.69 is 491.6% above this industry median. Based on the distribution chart, Milestone Scientific ranks #732 out of 782 companies in the Medical Devices & Instruments industry, which is in the bottom quartile relative to peers. Overall, Milestone Scientific has a GF Score™ of 37/100 and is considered Modestly Undervalued, reflecting its overall financial health beyond just this single metric.
How does Milestone Scientific's PB Ratio compare to NEPH and HBIO?
According to the Medical Devices & Instruments industry distribution chart, Milestone Scientific ranks #732 out of 782 companies for PB Ratio. This places Milestone Scientific in the lower half of its industry. The industry median PB Ratio is 2.15. Milestone Scientific's value of 12.69 is 491.6% above this benchmark. Historically, Milestone Scientific's own PB Ratio has ranged from 2.73 to 255.45 over the past decade. While the company's 10-year median is 7.50 vs. the industry median of 2.15, Milestone Scientific has consistently been above the industry average. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good PB Ratio for a Medical Devices & Instruments company?
The median PB Ratio among Medical Devices & Instruments companies is 2.15, based on 782 companies in the industry. Companies in the top quartile (top 25%) have a PB Ratio significantly above this median, while those in the bottom quartile fall well below. However, PB Ratio should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Milestone Scientific's current PB Ratio of 12.69 is 491.6% above the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high PB Ratio mean?
A high PB Ratio can signal that a stock is expensive relative to its fundamentals. Price-to-Book ratio is the ratio of share price to a company's book value per share. View historical data on Milestone Scientific and its competitors. For the Medical Devices & Instruments industry, the median PB Ratio is 2.15 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Milestone Scientific's current PB Ratio is 12.69, which is 69% above median its own 10-year median of 7.50. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Milestone Scientific stock overvalued right now?
Based on GuruFocus' analysis, Milestone Scientific (MLSS) is currently considered Modestly Undervalued. The stock's GF Value™ is $0.60, compared to a current price of $0.50 — trading 17.5% below its estimated fair value. The current PB Ratio is 12.69, which is 69% above median its 10-year median of 7.50 and 491.6% above the Medical Devices & Instruments industry median of 2.15. Milestone Scientific's overall GF Score™ is 37/100 with 3 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is PB Ratio calculated?
PB Ratio is calculated from a company's financial statements. For Milestone Scientific (MLSS), the current PB Ratio is 12.69 as of Aug. 16, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Is Milestone Scientific (MLSS) Overvalued in 2026?
Based on GuruFocus' analysis, Milestone Scientific stock appears to be undervalued.
The current stock price of $0.50 is trading 17.5% below its estimated GF Value™ of $0.60.
GuruFocus considers Milestone Scientific to be Modestly Undervalued.
Key valuation signals for MLSS:
PB Ratio: 12.69 (69% above median its 10-year median of 7.50)
GF Value™: $0.60 vs. price of $0.50 (17.5% below fair value)
Industry Position: 491.6% above the Medical Devices & Instruments median (#732 of 782)
No single metric tells the full story. See the MLSS stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.
Milestone Scientific Inc develops and commercializes proprietary computer-controlled drug delivery systems designed to enhance the safety, precision, and patient experience associated with subcutaneous injections and fluid aspiration procedures. The company's core technology platform, Dynamic Pressure Sensing (DPS) Technology, controls flow rate and measures pressure at the needle tip in real time. DPS Technology is incorporated into both the company's dental and medical products and supports clinical applications, including local anesthesia delivery, epidural space identification in regional anesthesia procedures, and intra-articular joint injections. It operates in two segments: Dental, which markets and sells its dental products, and Medical, markets and sells its medical products.
37GF Score
Get the complete analysis for MLSS
PB Ratio is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.
Quick Browse
Personalize
Premium Gurus 
Create New Portfolio
MLSS has been successfully added to your 
