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Advagene Biopharma CoROCO:6709 -3.47%30 Cyclically Adjusted PB Ratio is 4.64 as of Aug. 17, 2026. GuruFocus rates ROCO:6709 with a GF Score™ of 30/100. The stock has 2 warning signs investors should review. Among 692 Biotechnology companies, Advagene Biopharma Co ranks worse than 74.57% on this metric.
The historical rank and industry rank for Advagene Biopharma Co's Cyclically Adjusted PB Ratio or its related term are showing as below:
ROCO:6709'
s Cyclically Adjusted PB Ratio Range Over the Past 10 Years
Min: 0 Med: 0 Max: 4.63
Current: 4.63
During the past 10 years, Advagene Biopharma Co's highest Cyclically Adjusted PB Ratio was 4.63. The lowest was 0.00. And the median was 0.00.
ROCO:6709's Cyclically Adjusted PB Ratio is ranked worse than 74.57% of 692
companies
in the Biotechnology industry
Industry Median: 1.635
vs ROCO:6709: 4.63
The Shiller PE Ratio was first used by professor Robert Shiller. He uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings per share of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted book value per share of a company over the past 10 years.
Advagene Biopharma Co's adjusted book value per share data of for the fiscal year that ended in Dec25 was NT$2.552. Add all the adjusted book value per share for the past 10 years together and divide the count will get our Cyclically Adjusted Book per Share, which is NT$5.39 for the trailing ten years ended in Dec25.
Shiller PE for Stocks: The True Measure of Stock Valuation
Advagene Biopharma Co (ROCO:6709) Cyclically Adjusted PB Ratio Explanation
Compared with the regular PB Ratio, which works poorly for cyclical businesses, the Cyclically Adjusted PB Ratio smoothed out the fluctuations of book value during business cycles. Therefore it is more accurate in reflecting the valuation of the company.
If a company has consistent business performance, the Cyclically Adjusted PB Ratio should give similar results to regular PB Ratio.
Advagene Biopharma Co Cyclically Adjusted PB Ratio Related Terms
Advagene Biopharma Co Cyclically Adjusted PB Ratio Historical Data
* Premium members only.
The historical data trend for Advagene Biopharma Co's Cyclically Adjusted PB Ratio can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Advagene Biopharma Co Cyclically Adjusted PB Ratio Chart
ROCO:6709 vs VRTX, REGN, RVMD: Cyclically Adjusted PB Ratio Comparison
For the Biotechnology subindustry, Advagene Biopharma Co's Cyclically Adjusted PB Ratio, along with its competitors' market caps and Cyclically Adjusted PB Ratio data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
Advagene Biopharma Co Cyclically Adjusted PB Ratio vs Biotechnology Industry
For the Biotechnology industry and Healthcare sector, Advagene Biopharma Co's Cyclically Adjusted PB Ratio distribution charts can be found below:
* The bar in red indicates where Advagene Biopharma Co's Cyclically Adjusted PB Ratio falls into.
Advagene Biopharma Co Cyclically Adjusted PB Ratio Calculation
Like the Shiller PE Ratio, the Cyclically Adjusted PB Ratio takes the Book Value per Share from the past 10 years, adjusts it for inflation, and then calculates the average. This average is then used for the P/B calculation. Because it considers this 10-year average, it's often referred to as the CAPB Ratio.
The Shiller PE Ratio was first used by professor Robert Shiller to measure the valuation of the overall market. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.
What does a Cyclically Adjusted PB Ratio of 4.64 mean?
Advagene Biopharma Co (ROCO:6709) has a Cyclically Adjusted PB Ratio of 4.64 as of Aug. 17, 2026. Cyclically Adjusted PB Ratio is the ratio of share price to a company's inflation-adjusted book value per share over a 10-year period. View historical data on Advagene Biopharma Co and its competitors. According to the industry distribution chart, Advagene Biopharma Co ranks #516 out of 692 companies in the Biotechnology industry, placing it in the top 74.6%.
Is Advagene Biopharma Co's Cyclically Adjusted PB Ratio too high?
Advagene Biopharma Co's current Cyclically Adjusted PB Ratio is 4.64. The Biotechnology industry median Cyclically Adjusted PB Ratio is 1.64. Advagene Biopharma Co's value of 4.64 is 183.8% above this industry median. Based on the distribution chart, Advagene Biopharma Co ranks #516 out of 692 companies in the Biotechnology industry, which is below the industry midpoint. Overall, Advagene Biopharma Co has a GF Score™ of 30/100, reflecting its overall financial health beyond just this single metric.
How does Advagene Biopharma Co's Cyclically Adjusted PB Ratio compare to VRTX and REGN?
According to the Biotechnology industry distribution chart, Advagene Biopharma Co ranks #516 out of 692 companies for Cyclically Adjusted PB Ratio. This places Advagene Biopharma Co in the lower half of its industry. The industry median Cyclically Adjusted PB Ratio is 1.64. Advagene Biopharma Co's value of 4.64 is 183.8% above this benchmark. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Cyclically Adjusted PB Ratio for a Biotechnology company?
The median Cyclically Adjusted PB Ratio among Biotechnology companies is 1.64, based on 692 companies in the industry. Companies in the top quartile (top 25%) have a Cyclically Adjusted PB Ratio significantly above this median, while those in the bottom quartile fall well below. However, Cyclically Adjusted PB Ratio should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Advagene Biopharma Co's current Cyclically Adjusted PB Ratio of 4.64 is 183.8% above the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Cyclically Adjusted PB Ratio mean?
A high Cyclically Adjusted PB Ratio can signal that a stock is expensive relative to its fundamentals. Cyclically Adjusted PB Ratio is the ratio of share price to a company's inflation-adjusted book value per share over a 10-year period. View historical data on Advagene Biopharma Co and its competitors. For the Biotechnology industry, the median Cyclically Adjusted PB Ratio is 1.64 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Advagene Biopharma Co's current Cyclically Adjusted PB Ratio is 4.64. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Advagene Biopharma Co stock overvalued right now?
Advagene Biopharma Co (ROCO:6709) has a current Cyclically Adjusted PB Ratio of 4.64. The current Cyclically Adjusted PB Ratio is 4.64 and 183.8% above the Biotechnology industry median of 1.64. Advagene Biopharma Co's overall GF Score™ is 30/100 with 2 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Cyclically Adjusted PB Ratio calculated?
Cyclically Adjusted PB Ratio is calculated from a company's financial statements. For Advagene Biopharma Co (ROCO:6709), the current Cyclically Adjusted PB Ratio is 4.64 as of Aug. 17, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Advagene Biopharma Co Ltd is a Taiwan based immune-modulatory platform-based biotechnology company. The company has completed technology transfer with DCB for detoxified LT Adjuvant Technology Platform. Its product development includes nasal spray seasonal flu vaccine, nasal spray COVID-19 vaccine, Immunotherapy for COVID-19, Respiratory Allergy Immunotherapy - Allergic Rhinitis and Asthma ,and other vaccines.
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