Advagene Biopharma Co (ROCO:6709) E10: NT$-2.91 (As of Dec. 2025)

Author: Vera Yuan Vera Yuan
Vera Yuan
Vera Yuan
Director of Data and Quant Analytics at GuruFocus
Focused on building reliable datasets, financial models, and research tools for value-minded investors. Committed to turning complex data into practical guidance for value-investing and long-term wealth.
Reviewed by: Charlie Tian Charlie Tian
Charlie Tian
Charlie Tian
Founder & CEO of GuruFocus
Dr. Charlie Tian is the founder and CEO of GuruFocus.com, a leading global investment research platform established in 2004. With a Ph.D. in physics, Dr. Tian transitioned from science to finance, applying a data-driven, disciplined approach to value investing.

ROCO:6709 Advagene Biopharma Co Ltd ROCO:6709
36 GF Score
Price NT$24.55
! 2 Warning Signs
View Full Analysis

What is Advagene Biopharma Co E10?

Advagene Biopharma Co ROCO:6709 +0.41% 36 E10 is NT$-2.91 as of Dec. 2025. GuruFocus rates ROCO:6709 with a GF Score™ of 36/100. The stock has 2 warning signs investors should review.

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller P/E calculation. E10 is the average of the inflation adjusted earnings of a company over the past 10 years.

Advagene Biopharma Co's adjusted earnings per share data for the fiscal year that ended in Dec. 2025 was NT$-1.144. Add all the adjusted EPS for the past 10 years together and divide 10 will get our e10, which is NT$-2.91 for the trailing ten years ended in Dec. 2025.

Please click Growth Rate Calculation Example (GuruFocus) to see how GuruFocus calculates Wal-Mart Stores Inc (WMT)'s revenue growth rate. You can apply the same method to get the E10 growth rate using E10 data.

As of today (2026-07-16), Advagene Biopharma Co's current stock price is NT$ 24.55. Advagene Biopharma Co's E10 for the fiscal year that ended in Dec. 2025 was NT$-2.91. Advagene Biopharma Co's Shiller PE Ratio of today is .


Advagene Biopharma Co  (ROCO:6709) E10 Explanation

If a company grows much fast than inflation, E10 may underestimate the company's earnings power. Shiller PE Ratio can seem to be too high even the actual P/E is low.

For the Shiller P/E, the earnings of the past 10 years are inflation-adjusted and averaged. The result is used for P/E calculation. Since it looks at the average over the last 10 years, the Shiller P/E is also called PE10.

The Shiller P/E was first used by professor Robert Shiller to measure the valuation of the overall market. The same calculation is applied here to individual companies.


Be Aware

Shiller PE Ratio works better for cyclical companies. It gives you a better idea on the company's real earnings power.


Advagene Biopharma Co E10 Related Terms


Advagene Biopharma Co E10 Historical Data

* Premium members only.

The historical data trend for Advagene Biopharma Co's E10 can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Advagene Biopharma Co E10 Chart

Advagene Biopharma Co Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
E10
Get a 7-Day Free Trial Premium Member Only Premium Member Only 0.00 0.00 0.00 0.00 -2.91

Advagene Biopharma Co Semi-Annual Data
Dec16 Jun17 Dec17 Jun18 Dec18 Jun19 Dec19 Jun20 Dec20 Jun21 Dec21 Jun22 Dec22 Jun23 Dec23 Jun24 Dec24 Jun25 Dec25
E10 Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 0.00 0.00 0.00 0.00 -2.91

ROCO:6709 vs VRTX, REGN, ALNY: E10 Comparison

For the Biotechnology subindustry, Advagene Biopharma Co's Shiller PE Ratio, along with its competitors' market caps and Shiller PE Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Advagene Biopharma Co Shiller PE Ratio vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Advagene Biopharma Co's Shiller PE Ratio distribution charts can be found below:

* The bar in red indicates where Advagene Biopharma Co's Shiller PE Ratio falls into.


ROCO:6709
36GF Score
Advagene Biopharma Co Ltd ROCO:6709
E10 is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

Advagene Biopharma Co E10 Calculation

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller P/E calculation. When we calculate the today's Shiller P/E ratio of a stock, we use today's price divided by E10.

What is E10? How do we calculate E10?

E10 is the average of the inflation adjusted earnings of a company over the past 10 years. Let's use an example to explain.

If we want to calculate the E10 of Wal-Mart (WMT) for Dec. 31, 2010, we need to have the inflation data and the earnings from 2001 through 2010.

We adjusted the earnings of 2001 earnings data with the total inflation from 2001 through 2010 to the equivalent earnings in 2010. If the total inflation from 2001 to 2010 is 40%, and Wal-Mart earned $1 a share in 2001, then the 2001's equivalent earnings in 2010 is $1.4 a share. If Wal-Mart earns $1 again in 2002, and the total inflation from 2002 through 2010 is 35%, then the equivalent 2002 earnings in 2010 is $1.35. So on and so forth, you get the equivalent earnings of past 10 years. Then you add them together and divided the sum by 10 to get E10.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

For example, Advagene Biopharma Co's adjusted earnings per share data for the fiscal year that ended in Dec. 2025 was:

Adj_EPS=Earnings per Share (Diluted) /CPI of Dec. 2025 (Change)*Current CPI (Dec. 2025)
=-1.144/324.0540*324.0540
=-1.144

Current CPI (Dec. 2025) = 324.0540.

Advagene Biopharma Co Annual Data

per_share_eps CPI Adj_EPS
201612 -3.981 241.432 -5.343
201712 -4.666 246.524 -6.133
201812 -3.091 251.233 -3.987
201912 -2.041 256.974 -2.574
202012 -1.558 260.474 -1.938
202112 -1.874 278.802 -2.178
202212 -2.388 296.797 -2.607
202312 -1.821 306.746 -1.924
202412 -1.264 315.605 -1.298
202512 -1.144 324.054 -1.144

Add all the adjusted EPS together and divide 10 will get our e10.

Frequently Asked Questions Learn more about E10 →
What does a E10 of NT$-2.91 mean?
Advagene Biopharma Co (ROCO:6709) has a E10 of NT$-2.91 as of Dec. 2025. E10 represents the company's inflation-adjusted earnings per share over a 10-year period. View historical data on Advagene Biopharma Co and its competitors.
Is Advagene Biopharma Co's E10 too high?
Advagene Biopharma Co's current E10 is NT$-2.91. Overall, Advagene Biopharma Co has a GF Score™ of 36/100, reflecting its overall financial health beyond just this single metric.
How does Advagene Biopharma Co's E10 compare to VRTX and REGN?
Advagene Biopharma Co's E10 of NT$-2.91 can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good E10 for a Biotechnology company?
A good E10 depends on the Biotechnology industry context. However, E10 should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high E10 mean?
A high E10 can signal that a stock is expensive relative to its fundamentals. E10 represents the company's inflation-adjusted earnings per share over a 10-year period. View historical data on Advagene Biopharma Co and its competitors. Advagene Biopharma Co's current E10 is NT$-2.91. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Advagene Biopharma Co stock overvalued right now?
Advagene Biopharma Co (ROCO:6709) has a current E10 of NT$-2.91. The current E10 is NT$-2.91. Advagene Biopharma Co's overall GF Score™ is 36/100 with 2 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is E10 calculated?
E10 is calculated from a company's financial statements. For Advagene Biopharma Co (ROCO:6709), the current E10 is NT$-2.91 as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Advagene Biopharma Co Business Description

Address Sector 1, Neihu Road, 6 Floor, No.308, Neihu District, Taipei, TWN, 114
Advagene Biopharma Co Ltd is a Taiwan based immune-modulatory platform-based biotechnology company. The company has completed technology transfer with DCB for detoxified LT Adjuvant Technology Platform. Its product development includes nasal spray seasonal flu vaccine, nasal spray COVID-19 vaccine, Immunotherapy for COVID-19, Respiratory Allergy Immunotherapy - Allergic Rhinitis and Asthma ,and other vaccines.
36GF Score

Get the complete analysis for ROCO:6709

E10 is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

NT$24.55
Price