RaQualia Pharma (TSE:4579) Cyclically Adjusted PB Ratio: 1.91 (As of Aug. 03, 2026) — 35% Below Median

Author: Vera Yuan Vera Yuan
Vera Yuan
Vera Yuan
Director of Data and Quant Analytics at GuruFocus
Focused on building reliable datasets, financial models, and research tools for value-minded investors. Committed to turning complex data into practical guidance for value-investing and long-term wealth.
Reviewed by: Charlie Tian Charlie Tian
Charlie Tian
Charlie Tian
Founder & CEO of GuruFocus
Dr. Charlie Tian is the founder and CEO of GuruFocus.com, a leading global investment research platform established in 2004. With a Ph.D. in physics, Dr. Tian transitioned from science to finance, applying a data-driven, disciplined approach to value investing.

TSE:4579 RaQualia Pharma Inc TSE:4579
60 GF Score
Price 円482.00
GF Value 円311.11
Valuation Significantly Overvalued
! 4 Warning Signs
View Full Analysis

What is RaQualia Pharma Cyclically Adjusted PB Ratio?

RaQualia Pharma TSE:4579 60 Cyclically Adjusted PB Ratio is 1.91 as of Aug. 03, 2026, which is 35% below its 10-year median of 2.93. GuruFocus rates TSE:4579 with a GF Score™ of 60/100 and a GF Value™ of 円311.11 (Significantly Overvalued). The stock has 4 warning signs investors should review. Among 697 Biotechnology companies, RaQualia Pharma ranks worse than 53.66% on this metric.

As of today (2026-08-03), RaQualia Pharma's current share price is 円482.00. RaQualia Pharma's Cyclically Adjusted Book per Share for the quarter that ended in Mar. 2026 was 円251.85. RaQualia Pharma's Cyclically Adjusted PB Ratio for today is 1.91.

The historical rank and industry rank for RaQualia Pharma's Cyclically Adjusted PB Ratio or its related term are showing as below:

TSE:4579' s Cyclically Adjusted PB Ratio Range Over the Past 10 Years
Min: 1.32   Med: 2.93   Max: 5.23
Current: 1.8

During the past years, RaQualia Pharma's highest Cyclically Adjusted PB Ratio was 5.23. The lowest was 1.32. And the median was 2.93.

TSE:4579's Cyclically Adjusted PB Ratio is ranked worse than
53.66% of 697 companies
in the Biotechnology industry
Industry Median: 1.6 vs TSE:4579: 1.80

The Shiller PE Ratio was first used by professor Robert Shiller. He uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings per share of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted book value per share of a company over the past 10 years.

RaQualia Pharma's adjusted book value per share data for the three months ended in Mar. 2026 was 円310.812. Add all the adjusted book value per share for the past 10 years together and divide the count will get our Cyclically Adjusted Book per Share, which is 円251.85 for the trailing ten years ended in Mar. 2026.

Shiller PE for Stocks: The True Measure of Stock Valuation


RaQualia Pharma  (TSE:4579) Cyclically Adjusted PB Ratio Explanation

Compared with the regular PB Ratio, which works poorly for cyclical businesses, the Cyclically Adjusted PB Ratio smoothed out the fluctuations of book value during business cycles. Therefore it is more accurate in reflecting the valuation of the company.

If a company has consistent business performance, the Cyclically Adjusted PB Ratio should give similar results to regular PB Ratio.


RaQualia Pharma Cyclically Adjusted PB Ratio Related Terms


RaQualia Pharma Cyclically Adjusted PB Ratio Historical Data

* Premium members only.

The historical data trend for RaQualia Pharma's Cyclically Adjusted PB Ratio can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

RaQualia Pharma Cyclically Adjusted PB Ratio Chart

RaQualia Pharma Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Cyclically Adjusted PB Ratio
Get a 7-Day Free Trial Premium Member Only Premium Member Only 4.20 4.68 2.69 1.52 4.01

RaQualia Pharma Quarterly Data
Mar21 Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
Cyclically Adjusted PB Ratio Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 1.47 2.19 2.30 4.01 3.09

TSE:4579 vs VRTX, REGN, RVMD: Cyclically Adjusted PB Ratio Comparison

For the Biotechnology subindustry, RaQualia Pharma's Cyclically Adjusted PB Ratio, along with its competitors' market caps and Cyclically Adjusted PB Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


RaQualia Pharma Cyclically Adjusted PB Ratio vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, RaQualia Pharma's Cyclically Adjusted PB Ratio distribution charts can be found below:

* The bar in red indicates where RaQualia Pharma's Cyclically Adjusted PB Ratio falls into.


TSE:4579
60GF Score
RaQualia Pharma Inc TSE:4579
Cyclically Adjusted PB Ratio is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

RaQualia Pharma Cyclically Adjusted PB Ratio Calculation

Like the Shiller PE Ratio, the Cyclically Adjusted PB Ratio takes the Book Value per Share from the past 10 years, adjusts it for inflation, and then calculates the average. This average is then used for the P/B calculation. Because it considers this 10-year average, it's often referred to as the CAPB Ratio.

The Shiller PE Ratio was first used by professor Robert Shiller to measure the valuation of the overall market. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio.

RaQualia Pharma's Cyclically Adjusted PB Ratio for today is calculated as

Cyclically Adjusted PB Ratio=Share Price/ Cyclically Adjusted Book per Share
=482.00/251.85
=1.91

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

RaQualia Pharma's Cyclically Adjusted Book per Share for the quarter that ended in Mar. 2026 is calculated as:

For example, RaQualia Pharma's adjusted Book Value per Share data for the three months ended in Mar. 2026 was:

Adj_Book=Book Value per Share/CPI of Mar. 2026 (Change)*Current CPI (Mar. 2026)
=310.812/112.7000*112.7000
=310.812

Current CPI (Mar. 2026) = 112.7000.

RaQualia Pharma Quarterly Data

Book Value per Share CPI Adj_Book
201603 242.482 97.900 279.139
201606 221.084 98.100 253.987
201609 205.965 98.000 236.860
201612 201.845 98.400 231.178
201703 200.868 98.100 230.763
201706 190.252 98.500 217.679
201709 181.402 98.800 206.923
201712 240.845 99.400 273.071
201803 225.235 99.200 255.887
201806 213.284 99.200 242.310
201809 203.471 99.900 229.541
201812 189.184 99.700 213.852
201903 185.857 99.700 210.091
201906 191.196 99.800 215.910
201909 181.026 100.100 203.812
201912 220.556 100.500 247.330
202003 203.074 100.300 228.180
202006 198.134 99.900 223.521
202009 186.988 99.900 210.946
202012 191.444 99.300 217.278
202103 201.322 99.900 227.117
202106 207.280 99.500 234.778
202109 200.837 100.100 226.117
202112 228.490 100.100 257.251
202203 222.496 101.100 248.025
202206 250.729 101.800 277.575
202209 250.095 103.100 273.382
202212 262.048 104.100 283.697
202303 289.365 104.400 312.370
202306 300.601 105.200 322.032
202309 288.445 106.200 306.099
202312 283.052 106.800 298.689
202403 277.208 107.200 291.430
202406 261.025 108.200 271.881
202412 255.083 110.700 259.692
202503 251.859 111.100 255.486
202506 257.061 111.700 259.362
202509 247.061 112.000 248.605
202512 281.963 113.000 281.214
202603 310.812 112.700 310.812

Add all the adjusted book value per share together and divide the count will get our Cyclically Adjusted Book per Share.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

What does a Cyclically Adjusted PB Ratio of 1.91 mean?
RaQualia Pharma (TSE:4579) has a Cyclically Adjusted PB Ratio of 1.91 as of Aug. 03, 2026. Cyclically Adjusted PB Ratio is the ratio of share price to a company's inflation-adjusted book value per share over a 10-year period. View historical data on RaQualia Pharma and its competitors. This is 35% below median its historical median of 2.93. Over the past decade, RaQualia Pharma's Cyclically Adjusted PB Ratio has ranged from 1.32 to 5.23. According to the industry distribution chart, RaQualia Pharma ranks #374 out of 697 companies in the Biotechnology industry, placing it in the top 53.7%.
Is RaQualia Pharma's Cyclically Adjusted PB Ratio too high?
RaQualia Pharma's current Cyclically Adjusted PB Ratio of 1.91 is 35% below median its 10-year median of 2.93. Over the past 10 years, this metric has ranged from a low of 1.32 to a high of 5.23. The Biotechnology industry median Cyclically Adjusted PB Ratio is 1.60. RaQualia Pharma's value of 1.91 is 19.4% above this industry median. Based on the distribution chart, RaQualia Pharma ranks #374 out of 697 companies in the Biotechnology industry, which is below the industry midpoint. Overall, RaQualia Pharma has a GF Score™ of 60/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does RaQualia Pharma's Cyclically Adjusted PB Ratio compare to VRTX and REGN?
According to the Biotechnology industry distribution chart, RaQualia Pharma ranks #374 out of 697 companies for Cyclically Adjusted PB Ratio. This places RaQualia Pharma in the lower half of its industry. The industry median Cyclically Adjusted PB Ratio is 1.60. RaQualia Pharma's value of 1.91 is 19.4% above this benchmark. Historically, RaQualia Pharma's own Cyclically Adjusted PB Ratio has ranged from 1.32 to 5.23 over the past decade. While the company's 10-year median is 2.93 vs. the industry median of 1.60, RaQualia Pharma has consistently been above the industry average. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Cyclically Adjusted PB Ratio for a Biotechnology company?
The median Cyclically Adjusted PB Ratio among Biotechnology companies is 1.60, based on 697 companies in the industry. Companies in the top quartile (top 25%) have a Cyclically Adjusted PB Ratio significantly above this median, while those in the bottom quartile fall well below. However, Cyclically Adjusted PB Ratio should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. RaQualia Pharma's current Cyclically Adjusted PB Ratio of 1.91 is 19.4% above the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Cyclically Adjusted PB Ratio mean?
A high Cyclically Adjusted PB Ratio can signal that a stock is expensive relative to its fundamentals. Cyclically Adjusted PB Ratio is the ratio of share price to a company's inflation-adjusted book value per share over a 10-year period. View historical data on RaQualia Pharma and its competitors. For the Biotechnology industry, the median Cyclically Adjusted PB Ratio is 1.60 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. RaQualia Pharma's current Cyclically Adjusted PB Ratio is 1.91, which is 35% below median its own 10-year median of 2.93. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is RaQualia Pharma stock overvalued right now?
Based on GuruFocus' analysis, RaQualia Pharma (TSE:4579) is currently considered Significantly Overvalued. The stock's GF Value™ is 円311.11, compared to a current price of 円482.00 — trading 54.9% above its estimated fair value. The current Cyclically Adjusted PB Ratio is 1.91, which is 35% below median its 10-year median of 2.93 and 19.4% above the Biotechnology industry median of 1.60. RaQualia Pharma's overall GF Score™ is 60/100 with 4 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Cyclically Adjusted PB Ratio calculated?
Cyclically Adjusted PB Ratio is calculated from a company's financial statements. For RaQualia Pharma (TSE:4579), the current Cyclically Adjusted PB Ratio is 1.91 as of Aug. 03, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is RaQualia Pharma (TSE:4579) Overvalued in 2026?

Based on GuruFocus' analysis, RaQualia Pharma stock appears to be overvalued. The current stock price of 円482.00 is trading 54.9% above its estimated GF Value™ of 円311.11. GuruFocus considers RaQualia Pharma to be Significantly Overvalued.

Key valuation signals for TSE:4579:

  • Cyclically Adjusted PB Ratio: 1.91 (35% below median its 10-year median of 2.93)
  • GF Value™: 円311.11 vs. price of 円482.00 (54.9% above fair value)
  • GF Score™: 60/100 with 4 warning signs
  • Industry Position: 19.4% above the Biotechnology median (#374 of 697)

No single metric tells the full story. See the TSE:4579 stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


RaQualia Pharma Business Description

Address 1-21-19 Meieki Minami, Nakamura-ku, Nagoya, JPN, 470-2341
RaQualia Pharma Inc operates as a research and development-centered biotechnology company, generating revenue by creating the seeds for novel medicine and licensing them to pharmaceutical companies. The company manages the Sales and licensing of intellectual property for fundamental technologies related to pharmaceutical compounds and candidate compounds for clinical development. Its product portfolio includes, Tegoprazan (K-CAB), Galliprant and Elura both under Veterinary Medicines. The pipeline products include Potassium-Competitive Acid Blocker, Ghrelin Receptor Agonist, TRPM8 Blocker and 5-HT4 Agonist studied under different phases of development.
60GF Score

Get the complete analysis for TSE:4579

Cyclically Adjusted PB Ratio is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

円482.00
Price
円311.11
GF Value