RaQualia Pharma (TSE:4579) 3-Year ROIIC % : -8.85% (As of Dec. 2025)

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TSE:4579 RaQualia Pharma Inc TSE:4579
54 GF Score
Price 円453.00
GF Value 円310.66
Valuation Significantly Overvalued
! 4 Warning Signs
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What is RaQualia Pharma 3-Year ROIIC %?

RaQualia Pharma TSE:4579 -0.44% 54 3-Year ROIIC % is -8.85 as of Dec. 2025. GuruFocus rates TSE:4579 with a GF Score™ of 54/100 and a GF Value™ of 円310.66 (Significantly Overvalued). The stock has 4 warning signs investors should review. Among 1,322 Biotechnology companies, RaQualia Pharma ranks worse than 52.34% on this metric.

3-Year Return on Invested Incremental Capital (3-Year ROIIC %) measures the change in earnings as a percentage of change in investment over 3-year. RaQualia Pharma's 3-Year ROIIC % for the quarter that ended in Dec. 2025 was -8.85%. High ROIIC is generally an indication that your business is capital efficient or has a higher operating leverage.

The industry rank for RaQualia Pharma's 3-Year ROIIC % or its related term are showing as below:

TSE:4579's 3-Year ROIIC % is ranked worse than
52.34% of 1322 companies
in the Biotechnology industry
Industry Median: -4.9 vs TSE:4579: -8.85

RaQualia Pharma  (TSE:4579) 3-Year ROIIC % Explanation

Return on Incremental Invested Capital (ROIIC) is an extension of Return on Investment Capital (ROIC). ROIC % tells investors how efficiently that profitability is earned per dollar of company capital. ROIIC narrows the focus even further and shows how profitable each additional unit of capital investment could be. ROIIC % is a more powerful metric than ROIC because it measures how much money the company can generate going forward on future capital investments.

High ROIIC is generally an indication that your business is capital efficient or has a higher operating leverage.

Be Aware

It's important to keep in mind that when tracking ROIIC, the metric is better suited to forecasting the trend of future returns rather than measuring current return on investment.


RaQualia Pharma 3-Year ROIIC % Related Terms


RaQualia Pharma 3-Year ROIIC % Historical Data

* Premium members only.

The historical data trend for RaQualia Pharma's 3-Year ROIIC % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

RaQualia Pharma 3-Year ROIIC % Chart

RaQualia Pharma Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
3-Year ROIIC %
Get a 7-Day Free Trial Premium Member Only Premium Member Only 1,073.45 -134.86 17.45 -21.99 -8.85

RaQualia Pharma Quarterly Data
Mar21 Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
3-Year ROIIC % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 0.00 0.00 0.00 -8.85 0.00

TSE:4579 vs VRTX, REGN, ALNY: 3-Year ROIIC % Comparison

For the Biotechnology subindustry, RaQualia Pharma's 3-Year ROIIC %, along with its competitors' market caps and 3-Year ROIIC % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


RaQualia Pharma 3-Year ROIIC % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, RaQualia Pharma's 3-Year ROIIC % distribution charts can be found below:

* The bar in red indicates where RaQualia Pharma's 3-Year ROIIC % falls into.


TSE:4579
54GF Score
RaQualia Pharma Inc TSE:4579
3-Year ROIIC % is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

RaQualia Pharma 3-Year ROIIC % Calculation

RaQualia Pharma's 3-Year ROIIC % for the quarter that ended in Dec. 2025 is calculated as:

3-Year ROIIC %=3-Year Incremental Net Operating Profit After Taxes (NOPAT)**/3-Year Incremental Invested Capital**
=( 301.647792 (Dec. 2025) - 736.3006 (Dec. 2022) )/( 6875.831 (Dec. 2025) - 1966.372 (Dec. 2022) )
=-434.652808/4909.459
=-8.85%***

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

** Annual data of NOPAT and Invested Capital was used to calculate 3-Year ROIIC %.
*** Please be aware that the ROIIC (Return on Invested Capital) calculations are based on company-level data using the primary share class. The calculated data provided is for demonstration purposes and may slightly differ from the results displayed in the title due to potential variations caused by currency exchange rate differences throughout the year.

Frequently Asked Questions Learn more about 3-Year ROIIC % →
What does a 3-Year ROIIC % of -8.85 mean?
RaQualia Pharma (TSE:4579) has a 3-Year ROIIC % of -8.85 as of Dec. 2025. 3-Year ROIIC % measures the change in earnings as a percentage of change in investment over 3-year. View historical data on RaQualia Pharma and its competitors. According to the industry distribution chart, RaQualia Pharma ranks #692 out of 1322 companies in the Biotechnology industry, placing it in the top 52.3%.
Is RaQualia Pharma's 3-Year ROIIC % too high?
RaQualia Pharma's current 3-Year ROIIC % is -8.85. Based on the distribution chart, RaQualia Pharma ranks #692 out of 1322 companies in the Biotechnology industry, which is below the industry midpoint. Overall, RaQualia Pharma has a GF Score™ of 54/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does RaQualia Pharma's 3-Year ROIIC % compare to VRTX and REGN?
According to the Biotechnology industry distribution chart, RaQualia Pharma ranks #692 out of 1322 companies for 3-Year ROIIC %. This places RaQualia Pharma in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good 3-Year ROIIC % for a Biotechnology company?
A good 3-Year ROIIC % depends on the Biotechnology industry context. However, 3-Year ROIIC % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high 3-Year ROIIC % mean?
A high 3-Year ROIIC % can signal that a stock is expensive relative to its fundamentals. 3-Year ROIIC % measures the change in earnings as a percentage of change in investment over 3-year. View historical data on RaQualia Pharma and its competitors. RaQualia Pharma's current 3-Year ROIIC % is -8.85. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is RaQualia Pharma stock overvalued right now?
Based on GuruFocus' analysis, RaQualia Pharma (TSE:4579) is currently considered Significantly Overvalued. The stock's GF Value™ is 円310.66, compared to a current price of 円453.00 — trading 45.8% above its estimated fair value. The current 3-Year ROIIC % is -8.85. RaQualia Pharma's overall GF Score™ is 54/100 with 4 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is 3-Year ROIIC % calculated?
3-Year ROIIC % is calculated from a company's financial statements. For RaQualia Pharma (TSE:4579), the current 3-Year ROIIC % is -8.85 as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is RaQualia Pharma (TSE:4579) Overvalued in 2026?

Based on GuruFocus' analysis, RaQualia Pharma stock appears to be overvalued. The current stock price of 円453.00 is trading 45.8% above its estimated GF Value™ of 円310.66. GuruFocus considers RaQualia Pharma to be Significantly Overvalued.

Key valuation signals for TSE:4579:

  • 3-Year ROIIC %: -8.85
  • GF Value™: 円310.66 vs. price of 円453.00 (45.8% above fair value)
  • GF Score™: 54/100 with 4 warning signs

No single metric tells the full story. See the TSE:4579 stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


RaQualia Pharma Business Description

Address 1-21-19 Meieki Minami, Nakamura-ku, Nagoya, JPN, 470-2341
RaQualia Pharma Inc operates as a research and development-centered biotechnology company, generating revenue by creating the seeds for novel medicine and licensing them to pharmaceutical companies. The company manages the Sales and licensing of intellectual property for fundamental technologies related to pharmaceutical compounds and candidate compounds for clinical development. Its product portfolio includes, Tegoprazan (K-CAB), Galliprant and Elura both under Veterinary Medicines. The pipeline products include Potassium-Competitive Acid Blocker, Ghrelin Receptor Agonist, TRPM8 Blocker and 5-HT4 Agonist studied under different phases of development.
54GF Score

Get the complete analysis for TSE:4579

3-Year ROIIC % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

円453.00
Price
円310.66
GF Value