RaQualia Pharma (TSE:4579) Operating Margin %: -19.97% (As of Mar. 2026)


TSE:4579 RaQualia Pharma Inc TSE:4579
57 GF Score
Price 円468.00
GF Value 円961.31
Valuation Significantly Undervalued
! 3 Warning Signs
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What is RaQualia Pharma Operating Margin %?

RaQualia Pharma TSE:4579 -2.70% 57 Operating Margin % is -19.97% as of Mar. 2026. GuruFocus rates TSE:4579 with a GF Score™ of 57/100 and a GF Value™ of 円961.31 (Significantly Undervalued). The stock has 3 warning signs investors should review. Among 935 Biotechnology companies, RaQualia Pharma ranks better than 59.36% on this metric.

Operating Margin % is calculated as Operating Income divided by its Revenue. RaQualia Pharma's Operating Income for the three months ended in Mar. 2026 was 円-160 Mil. RaQualia Pharma's Revenue for the three months ended in Mar. 2026 was 円802 Mil. Therefore, RaQualia Pharma's Operating Margin % for the quarter that ended in Mar. 2026 was -19.97%.

The historical rank and industry rank for RaQualia Pharma's Operating Margin % or its related term are showing as below:

TSE:4579' s Operating Margin % Range Over the Past 10 Years
Min: -144.4   Med: -8.74   Max: 29.69
Current: -32.31


TSE:4579's Operating Margin % is ranked better than
59.36% of 935 companies
in the Biotechnology industry
Industry Median: -86.33 vs TSE:4579: -32.31

RaQualia Pharma's 5-Year Average Operating Margin % Growth Rate was 0.00% per year.

RaQualia Pharma's Operating Income for the three months ended in Mar. 2026 was 円-160 Mil. Its Operating Income for the trailing twelve months (TTM) ended in Mar. 2026 was 円-444 Mil.


RaQualia Pharma  (TSE:4579) Operating Margin % Explanation

Just like Gross Margin %, it is important to see a company maintains its operating margin over time. Among the same industry, a company with higher operating margin is more efficient in its operation. It is also more stable during industry slowdown or recessions. Peter Lynch prefers those with higher margins than those with lower margins.


Be Aware

Operating Margin % can be manipulated by adjusting the rate of depreciation, depletion and amortization (DDA).

If a company is facing competition, its Operating Margin % may decline. Often the Operating Margin % declines well before the company's Revenue or even profit decline. Therefore, Operating Margin % is a very important indicator of whether the company is facing problems.

For instance, by 2012, Nokia (NOK)'s problems were well known and its stock had lost more than 90% of its market value since 2007. But Nokia’s Operating Margin % had already been in decline since 2002, although its Earnings per Share (Diluted) were still rising. Investors who paid attention to Operating Margin % would have avoided this huge loss. The same can be said for Research-in-Motion (RIMM).

Therefore, Operating Margin % is a very important screening filter for GuruFocus. GuruFocus's Buffett-Munger screener requires that the profit margin is either consistent or expanding. The Model Portfolio of the Buffett-Munger screener has outperformed the market every year since inception in 2009.


RaQualia Pharma Operating Margin % Related Terms


RaQualia Pharma Operating Margin % Historical Data

* Premium members only.

The historical data trend for RaQualia Pharma's Operating Margin % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

RaQualia Pharma Operating Margin % Chart

RaQualia Pharma Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Operating Margin %
Get a 7-Day Free Trial Premium Member Only Premium Member Only 25.50 29.69 -17.74 -6.87 12.15

RaQualia Pharma Quarterly Data
Dec20 Mar21 Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Dec24 Mar25 Jun25 Dec25 Mar26
Operating Margin % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 0.00 9.64 -49.65 0.00 -19.97

TSE:4579 vs VRTX, REGN, ALNY: Operating Margin % Comparison

For the Biotechnology subindustry, RaQualia Pharma's Operating Margin %, along with its competitors' market caps and Operating Margin % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


RaQualia Pharma Operating Margin % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, RaQualia Pharma's Operating Margin % distribution charts can be found below:

* The bar in red indicates where RaQualia Pharma's Operating Margin % falls into.


TSE:4579
57GF Score
RaQualia Pharma Inc TSE:4579
Operating Margin % is just one metric. See GF Score™, valuation, warning signs, and more.
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RaQualia Pharma Operating Margin % Calculation

Operating Margin % - also known as operating income margin, operating profit margin and return on sales (ROS) - is the ratio of Operating Income divided by net sales or Revenue, usually presented in percent.

RaQualia Pharma's Operating Margin % for the fiscal year that ended in Dec. 2025 is calculated as

Operating Margin %=Operating Income (A: Dec. 2025 ) / Revenue (A: Dec. 2025 )
=483.72 / 3979.956
=12.15 %

RaQualia Pharma's Operating Margin % for the quarter that ended in Mar. 2026 is calculated as

Operating Margin %=Operating Income (Q: Mar. 2026 ) / Revenue (Q: Mar. 2026 )
=-160.198 / 801.993
=-19.97 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about Operating Margin % →
What does a Operating Margin % of -19.97% mean?
RaQualia Pharma (TSE:4579) has a Operating Margin % of -19.97% as of Mar. 2026. Operating margin is the ratio of total operating income to net sales. View historical data on RaQualia Pharma and its competitors. According to the industry distribution chart, RaQualia Pharma ranks #380 out of 935 companies in the Biotechnology industry, placing it in the top 40.6%.
Is RaQualia Pharma's Operating Margin % too high?
RaQualia Pharma's current Operating Margin % is -19.97%. Based on the distribution chart, RaQualia Pharma ranks #380 out of 935 companies in the Biotechnology industry, which is above the industry midpoint. Overall, RaQualia Pharma has a GF Score™ of 57/100 and is considered Significantly Undervalued, reflecting its overall financial health beyond just this single metric.
How does RaQualia Pharma's Operating Margin % compare to VRTX and REGN?
According to the Biotechnology industry distribution chart, RaQualia Pharma ranks #380 out of 935 companies for Operating Margin %. This puts RaQualia Pharma in the upper half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Operating Margin % for a Biotechnology company?
A good Operating Margin % depends on the Biotechnology industry context. However, Operating Margin % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Operating Margin % mean?
A high Operating Margin % can signal that a stock is expensive relative to its fundamentals. Operating margin is the ratio of total operating income to net sales. View historical data on RaQualia Pharma and its competitors. RaQualia Pharma's current Operating Margin % is -19.97%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is RaQualia Pharma stock overvalued right now?
Based on GuruFocus' analysis, RaQualia Pharma (TSE:4579) is currently considered Significantly Undervalued. The stock's GF Value™ is 円961.31, compared to a current price of 円468.00 — trading 51.3% below its estimated fair value. The current Operating Margin % is -19.97%. RaQualia Pharma's overall GF Score™ is 57/100 with 3 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Operating Margin % calculated?
Operating Margin % is calculated from a company's financial statements. For RaQualia Pharma (TSE:4579), the current Operating Margin % is -19.97% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is RaQualia Pharma (TSE:4579) Overvalued in 2026?

Based on GuruFocus' analysis, RaQualia Pharma stock appears to be undervalued. The current stock price of 円468.00 is trading 51.3% below its estimated GF Value™ of 円961.31. GuruFocus considers RaQualia Pharma to be Significantly Undervalued.

Key valuation signals for TSE:4579:

  • Operating Margin %: -19.97%
  • GF Value™: 円961.31 vs. price of 円468.00 (51.3% below fair value)
  • GF Score™: 57/100 with 3 warning signs

No single metric tells the full story. See the TSE:4579 stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


RaQualia Pharma Business Description

Address 1-21-19 Meieki Minami, Nakamura-ku, Nagoya, JPN, 470-2341
RaQualia Pharma Inc operates as a research and development-centered biotechnology company, generating revenue by creating the seeds for novel medicine and licensing them to pharmaceutical companies. The company manages the Sales and licensing of intellectual property for fundamental technologies related to pharmaceutical compounds and candidate compounds for clinical development. Its product portfolio includes, Tegoprazan (K-CAB), Galliprant and Elura both under Veterinary Medicines. The pipeline products include Potassium-Competitive Acid Blocker, Ghrelin Receptor Agonist, TRPM8 Blocker and 5-HT4 Agonist studied under different phases of development.
57GF Score

Get the complete analysis for TSE:4579

Operating Margin % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

円468.00
Price
円961.31
GF Value