ZVRA (Zevra Therapeutics) Cyclically Adjusted PB Ratio: (As of Aug. 13, 2026)

Author: Vera Yuan Vera Yuan
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Director of Data and Quant Analytics at GuruFocus
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Dr. Charlie Tian is the founder and CEO of GuruFocus.com, a leading global investment research platform established in 2004. With a Ph.D. in physics, Dr. Tian transitioned from science to finance, applying a data-driven, disciplined approach to value investing.

ZVRA Zevra Therapeutics Inc ZVRA
69 GF Score
Price $11.25
GF Value $20.92
Valuation Possible Value Trap
! 5 Warning Signs
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What is Zevra Therapeutics Cyclically Adjusted PB Ratio?

Shiller PE for Stocks: The True Measure of Stock Valuation


Zevra Therapeutics  (NAS:ZVRA) Cyclically Adjusted PB Ratio Explanation

Compared with the regular PB Ratio, which works poorly for cyclical businesses, the Cyclically Adjusted PB Ratio smoothed out the fluctuations of book value during business cycles. Therefore it is more accurate in reflecting the valuation of the company.

If a company has consistent business performance, the Cyclically Adjusted PB Ratio should give similar results to regular PB Ratio.


Zevra Therapeutics Cyclically Adjusted PB Ratio Related Terms


Zevra Therapeutics Cyclically Adjusted PB Ratio Historical Data

* Premium members only.

The historical data trend for Zevra Therapeutics's Cyclically Adjusted PB Ratio can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Zevra Therapeutics Cyclically Adjusted PB Ratio Chart

Zevra Therapeutics Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Cyclically Adjusted PB Ratio
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Zevra Therapeutics Quarterly Data
Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26 Jun26
Cyclically Adjusted PB Ratio Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 0.00 0.00 0.00 0.00 0.00

ZVRA vs TECX, RLMD, ALT: Cyclically Adjusted PB Ratio Comparison

For the Biotechnology subindustry, Zevra Therapeutics's Cyclically Adjusted PB Ratio, along with its competitors' market caps and Cyclically Adjusted PB Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Zevra Therapeutics Cyclically Adjusted PB Ratio vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Zevra Therapeutics's Cyclically Adjusted PB Ratio distribution charts can be found below:

* The bar in red indicates where Zevra Therapeutics's Cyclically Adjusted PB Ratio falls into.


ZVRA
69GF Score
Zevra Therapeutics Inc ZVRA
Cyclically Adjusted PB Ratio is just one metric. See GF Score™, valuation, warning signs, and more.
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Zevra Therapeutics Cyclically Adjusted PB Ratio Calculation

Like the Shiller PE Ratio, the Cyclically Adjusted PB Ratio takes the Book Value per Share from the past 10 years, adjusts it for inflation, and then calculates the average. This average is then used for the P/B calculation. Because it considers this 10-year average, it's often referred to as the CAPB Ratio.

The Shiller PE Ratio was first used by professor Robert Shiller to measure the valuation of the overall market. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio.

Zevra Therapeutics's Cyclically Adjusted Book per Share for the quarter that ended in Jun. 2026 is calculated as:

For example, Zevra Therapeutics's adjusted Book Value per Share data for the three months ended in Jun. 2026 was:

Adj_Book=Book Value per Share/CPI of Jun. 2026 (Change)*Current CPI (Jun. 2026)
=3.668/333.9520*333.9520
=3.668

Current CPI (Jun. 2026) = 333.9520.

Zevra Therapeutics Quarterly Data

Book Value per Share CPI Adj_Book
201609 -10.713 241.428 -14.819
201612 -20.433 241.432 -28.263
201703 -37.081 243.801 -50.793
201706 -42.879 244.955 -58.458
201709 -52.511 246.819 -71.049
201712 -62.790 246.524 -85.058
201803 -84.410 249.554 -112.957
201806 -84.049 251.989 -111.387
201809 -95.060 252.439 -125.755
201812 -40.270 251.233 -53.529
201903 -42.788 254.202 -56.212
201906 -45.203 256.143 -58.934
201909 -34.891 256.759 -45.381
201912 -32.771 256.974 -42.588
202003 -19.356 258.115 -25.043
202006 -14.964 257.797 -19.384
202009 -13.753 260.280 -17.646
202012 -14.638 260.474 -18.767
202103 2.958 264.877 3.729
202106 3.736 271.696 4.592
202109 3.730 274.310 4.541
202112 3.631 278.802 4.349
202203 3.530 287.504 4.100
202206 2.877 296.311 3.242
202209 2.719 296.808 3.059
202212 2.175 296.797 2.447
202303 2.107 301.836 2.331
202306 2.019 305.109 2.210
202309 1.863 307.789 2.021
202312 1.489 306.746 1.621
202403 1.166 312.332 1.247
202406 0.773 314.175 0.822
202409 1.311 315.301 1.389
202412 0.739 315.605 0.782
202503 0.750 319.799 0.783
202506 2.128 322.561 2.203
202509 2.369 324.800 2.436
202512 2.720 324.054 2.803
202603 3.481 330.213 3.520
202606 3.668 333.952 3.668

Add all the adjusted book value per share together and divide the count will get our Cyclically Adjusted Book per Share.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

Is Zevra Therapeutics (ZVRA) Overvalued in 2026?

Based on GuruFocus' analysis, Zevra Therapeutics stock appears to be undervalued. The current stock price of $11.25 is trading 46.2% below its estimated GF Value™ of $20.92. GuruFocus considers Zevra Therapeutics to be Possible Value Trap.

Key valuation signals for ZVRA:

  • Cyclically Adjusted PB Ratio:
  • GF Value™: $20.92 vs. price of $11.25 (46.2% below fair value)
  • GF Score™: 69/100 with 5 warning signs

No single metric tells the full story. See the ZVRA stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Zevra Therapeutics Business Description

Other Exchanges 1GDA:Germany
Address 101 Federal Street, Boston, MA, USA, 02110
Zevra Therapeutics Inc is a commercial-stage company with a late-stage pipeline committed to bringing life-changing therapeutics to people living with rare diseases. The Company is focused on expanding patient access, progressing its pipeline toward key milestones, and delivering meaningful outcomes for patients with unmet needs. The commercialization of its product, marketed in the United States for Niemann-Pick disease type C (NPC), a rare, progressive neurodegenerative disease, provides a corporate foundation and demonstrates its ability to advance therapies from development to market.
69GF Score

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Cyclically Adjusted PB Ratio is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$11.25
Price
$20.92
GF Value