Prime Medicine Inc

NEW
NAS:PRME (USA)  
$ 3.43 +0.26 (+8.03%) 10:08 PM EST
At Loss
P/B:
8.07
Market Cap:
$ 619.52M
Enterprise V:
$ 598.53M
Volume:
7.64M
Avg Vol (2M):
2.85M
Trade In:
Volume:
7.64M
At Loss
Avg Vol (2M):
2.85M

Business Description

Prime Medicine Inc
NAICS : 541714 SIC : 2833
ISIN : US74168J1016

Total Employee Number:

146
Description
Prime Medicine Inc is a biotechnology company focused on developing a new class of genetic medicines designed to provide durable, and potentially curative, treatment options for patients with diseases driven by defined genetic alterations, acquired cellular dysfunction, or dysregulated gene expression. Its program, PM577 for Wilson Disease, is designed to initially correct the H1069Q mutation in the ATP7B gene and is supported by preclinical data showing targeted correction and restoration of copper homeostasis in animal models. In addition, PM647 is being developed for alpha-1 antitrypsin deficiency, or AATD, another liver targeted disease with substantial unmet need.
Name Current Vs Industry Vs History
Cash-To-Debt
1.18
Equity-to-Asset
0.26
Debt-to-Equity
1.49
Debt-to-EBITDA
-0.58
Interest Coverage
N/A
N/A
N/A
Piotroski F-Score
3/9
0
1
2
3
4
5
6
7
8
9
Altman Z-Score
-4.54
Distress
Grey
Safe
Beneish M-Score
-4.07
Manipulator
Not Manipulator
WACC vs ROIC
WACC
ROIC
Name Current Vs Industry Vs History
5-Day RSI
70.71
9-Day RSI
62.59
14-Day RSI
57.64
3-1 Month Momentum %
-18.41
6-1 Month Momentum %
-15.14
12-1 Month Momentum %
12.08

Liquidity Ratio

Name Current Vs Industry Vs History
Current Ratio
3.8
Quick Ratio
3.8
Cash Ratio
3.73

Dividend & Buy Back

Name Current Vs Industry Vs History
3-Year Average Share Buyback Ratio
-22.9
Shareholder Yield %
-9.04
Name Current Vs Industry Vs History
Operating Margin %
-5121.77
Net Margin %
-4917.55
EBITDA Margin %
-4936.42
FCF Margin %
-3935.05
OCF Margin %
-3877.47
ROE %
-188.15
ROA %
-60.86
ROIC %
-113.88
3-Year ROIIC %
-89.07
ROC (Joel Greenblatt) %
-142.85
ROCE %
-71.12
Moat Score
6
Tariff Resilience Score
8

GF Value Rank

Name Current Vs Industry Vs History
PS Ratio
127.04
PB Ratio
8.07
Price-to-Tangible-Book
7.98
EV-to-EBIT
-2.9
EV-to-EBITDA
-3.01
EV-to-Revenue
148.37
EV-to-Forward-Revenue
23.54
EV-to-FCF
-3.77
Earnings Yield (Greenblatt) %
-34.48
FCF Yield %
-25.62

Financials (Next Earnings Date:2026-08-07 Est.)

PRME's 30-Y Financials
Income Statement Breakdown FY
Not Enough Data
Balance Sheet Breakdown
Not Enough Data
Cashflow Statement Breakdown
Not Enough Data

Operating Revenue by Business Segment

Operating Revenue by Geographic Region

Historical Operating Revenue by Business Segment

Historical Operating Revenue by Geographic Region

5-Step DuPont Analysis as of
Not Enough Data

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Performance

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Log
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Annualized Return %  

Symbol
1 Week
1 Month
3 Months
6 Months
YTD
1 Year
3 Years
5 Years
10 Years

Total Annual Return %  

Symbol
2026
2025
2024
2023
2022
2021
2020
2019
2018
2017

Prime Medicine Inc Executives

Details

GF Value™

Valuation Chart

Year:

Analyst Estimate

Key Statistics

Name Value
Revenue (TTM) (Mil $) 4.034
EPS (TTM) ($) -1.25
Beta 3.1166
3-Year Sharpe Ratio -0.06
3-Year Sortino Ratio -0.11
Volatility % 143.46
14-Day RSI 57.64
14-Day ATR ($) 0.277484
20-Day SMA ($) 3.12375
12-1 Month Momentum % 12.08
52-Week Range ($) 2.28 - 6.94
Shares Outstanding (Mil) 180.62

Piotroski F-Score Details

Year:
Component Result
Piotroski F-Score 3
Positive ROA
Positive CFROA
Higher ROA yoy
CFROA > ROA
Lower Leverage yoy
Higher Current Ratio yoy
Less Shares Outstanding yoy
Higher Gross Margin yoy
Higher Asset Turnover yoy

Prime Medicine Inc Filings

Filing Date Document Date Form
No Filing Data

Prime Medicine Inc Stock Events

Financials Calendars
Event Date Price ($)
Third quarter earnings results for 2026 2026-11-06 In 131 days
Second quarter earnings results for 2026 2026-08-07 In 40 days
Goldman Sachs 47th Annual Global Healthcare Conference 2026-06-10 10:40 2.88 (-3.68%)
General meeting for 2026 2026-06-05 14:00 3.47 (+9.46%)
Jefferies Global Healthcare Conference 2026-06-04 12:50 3.14 (-3.98%)
First quarter earnings results for 2026 2026-05-07 3.41 (-1.16%)
The Citizens Life Sciences Conference 2026-03-11 14:15 4.05 (-2.64%)
TD Cowen 46th Annual Health Care Conference 2026-03-04 13:10 4.23 (-5.16%)
Annual report for 2025 2026-03-03 4.66 (+5.91%)
Fourth quarter earnings results for 2025 2026-03-03 4.66 (+5.91%)
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Prime Medicine Inc Frequently Asked Questions

What is Prime Medicine Inc(PRME)'s stock price today?
The current price of PRME is $3.43. The 52 week high of PRME is $6.94 and 52 week low is $2.28.
When is next earnings date of Prime Medicine Inc(PRME)?
The next earnings date of Prime Medicine Inc(PRME) is 2026-08-07 Est..
Does Prime Medicine Inc(PRME) pay dividends? If so, how much?
Prime Medicine Inc(PRME) does not pay dividend.

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