Ono Pharmaceutical Co (MEX:4528N) Cyclically Adjusted PS Ratio: 2.85 (As of Aug. 15, 2026) — 52% Below Median

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MEX:4528N Ono Pharmaceutical Co Ltd MEX:4528N
89 GF Score
Price MXN341.69
GF Value MXN311.93
! 2 Warning Signs
View Full Analysis

What is Ono Pharmaceutical Co Cyclically Adjusted PS Ratio?

Ono Pharmaceutical Co MEX:4528N 89 Cyclically Adjusted PS Ratio is 2.85 as of Aug. 15, 2026, which is 52% below its 10-year median of 5.93. GuruFocus rates MEX:4528N with a GF Score™ of 89/100 and a GF Value™ of MXN311.93. The stock has 2 warning signs investors should review. Among 751 Drug Manufacturers companies, Ono Pharmaceutical Co ranks worse than 60.19% on this metric.

As of today (2026-08-15), Ono Pharmaceutical Co's current share price is MXN341.69. Ono Pharmaceutical Co's Cyclically Adjusted Revenue per Share for the quarter that ended in Jun. 2026 was MXN119.75. Ono Pharmaceutical Co's Cyclically Adjusted PS Ratio for today is 2.85.

The historical rank and industry rank for Ono Pharmaceutical Co's Cyclically Adjusted PS Ratio or its related term are showing as below:

MEX:4528N' s Cyclically Adjusted PS Ratio Range Over the Past 10 Years
Min: 2.05   Med: 5.93   Max: 10.51
Current: 2.84

During the past years, Ono Pharmaceutical Co's highest Cyclically Adjusted PS Ratio was 10.51. The lowest was 2.05. And the median was 5.93.

MEX:4528N's Cyclically Adjusted PS Ratio is ranked worse than
60.19% of 751 companies
in the Drug Manufacturers industry
Industry Median: 2.04 vs MEX:4528N: 2.84

The Shiller PE Ratio was first used by professor Robert Shiller. He uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings per share of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PS Ratio. The Cyclically Adjusted Revenue per Share is the average of the inflation adjusted revenue per share of a company over the past 10 years.

Ono Pharmaceutical Co's adjusted revenue per share data for the three months ended in Jun. 2026 was MXN26.821. Add all the adjusted revenue per share for the past 10 years together and divide 10 will get our Cyclically Adjusted Revenue per Share, which is MXN119.75 for the trailing ten years ended in Jun. 2026.

Shiller PE for Stocks: The True Measure of Stock Valuation


Ono Pharmaceutical Co  (MEX:4528N) Cyclically Adjusted PS Ratio Explanation

Compared with the regular PS Ratio, which works poorly for cyclical businesses, the Cyclically Adjusted PS Ratio smoothed out the fluctuations of revenue during business cycles. Therefore it is more accurate in reflecting the valuation of the company.

If a company has consistent business performance, the Cyclically Adjusted PS Ratio should give similar results to regular PS Ratio.


Ono Pharmaceutical Co Cyclically Adjusted PS Ratio Related Terms


Ono Pharmaceutical Co Cyclically Adjusted PS Ratio Historical Data

* Premium members only.

The historical data trend for Ono Pharmaceutical Co's Cyclically Adjusted PS Ratio can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Ono Pharmaceutical Co Cyclically Adjusted PS Ratio Chart

Ono Pharmaceutical Co Annual Data
Trend Mar17 Mar18 Mar19 Mar20 Mar21 Mar22 Mar23 Mar24 Mar25 Mar26
Cyclically Adjusted PS Ratio
Get a 7-Day Free Trial Premium Member Only Premium Member Only 6.58 5.08 3.86 2.19 3.07

Ono Pharmaceutical Co Quarterly Data
Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26 Jun26
Cyclically Adjusted PS Ratio Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 2.06 2.19 2.70 3.07 2.85

MEX:4528N vs LLY, JNJ, ABBV: Cyclically Adjusted PS Ratio Comparison

For the Drug Manufacturers - General subindustry, Ono Pharmaceutical Co's Cyclically Adjusted PS Ratio, along with its competitors' market caps and Cyclically Adjusted PS Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Ono Pharmaceutical Co Cyclically Adjusted PS Ratio vs Drug Manufacturers Industry

For the Drug Manufacturers industry and Healthcare sector, Ono Pharmaceutical Co's Cyclically Adjusted PS Ratio distribution charts can be found below:

* The bar in red indicates where Ono Pharmaceutical Co's Cyclically Adjusted PS Ratio falls into.


MEX:4528N
89GF Score
Ono Pharmaceutical Co Ltd MEX:4528N
Cyclically Adjusted PS Ratio is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

Ono Pharmaceutical Co Cyclically Adjusted PS Ratio Calculation

Like the Shiller PE Ratio, the Cyclically Adjusted PS Ratio takes the Revenue per Share from the past 10 years, adjusts it for inflation, and then calculates the average. This average is then used for the P/S calculation. Because it considers this 10-year average, it's often referred to as the CAPS Ratio.

The Shiller PE Ratio was first used by professor Robert Shiller to measure the valuation of the overall market. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PS Ratio.

Ono Pharmaceutical Co's Cyclically Adjusted PS Ratio for today is calculated as

Cyclically Adjusted PS Ratio=Share Price/ Cyclically Adjusted Revenue per Share
=341.69/119.75
=2.85

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Ono Pharmaceutical Co's Cyclically Adjusted Revenue per Share for the quarter that ended in Jun. 2026 is calculated as:

For example, Ono Pharmaceutical Co's adjusted Revenue per Share data for the three months ended in Jun. 2026 was:

Adj_RevenuePerShare=Revenue per Share/CPI of Jun. 2026 (Change)*Current CPI (Jun. 2026)
=26.821/113.6000*113.6000
=26.821

Current CPI (Jun. 2026) = 113.6000.

Ono Pharmaceutical Co Quarterly Data

Revenue per Share CPI Adj_RevenuePerShare
201609 21.135 98.000 24.499
201612 23.848 98.400 27.532
201703 17.602 98.100 20.383
201706 18.811 98.500 21.695
201709 19.215 98.800 22.093
201712 26.761 99.400 30.584
201803 20.397 99.200 23.358
201806 24.737 99.200 28.328
201809 23.741 99.900 26.997
201812 26.821 99.700 30.560
201903 22.212 99.700 25.309
201906 25.639 99.800 29.184
201909 27.343 100.100 31.031
201912 26.419 100.500 29.863
202003 29.254 100.300 33.133
202006 32.198 99.900 36.614
202009 31.668 99.900 36.011
202012 32.424 99.300 37.093
202103 28.008 99.900 31.849
202106 31.638 99.500 36.121
202109 32.421 100.100 36.793
202112 35.244 100.100 39.997
202203 30.808 101.100 34.617
202206 32.821 101.800 36.625
202209 31.618 103.100 34.838
202212 36.197 104.100 39.500
202303 29.863 104.400 32.495
202306 29.805 105.200 32.185
202309 33.767 106.200 36.120
202312 32.504 106.800 34.574
202403 26.431 107.200 28.009
202406 29.055 108.200 30.505
202409 35.972 108.900 37.525
202412 38.726 110.700 39.741
202503 32.799 111.100 33.537
202506 35.342 111.700 35.943
202509 34.219 112.000 34.708
202512 34.375 113.000 34.558
202603 28.726 112.700 28.955
202606 26.821 113.600 26.821

Add all the adjusted revenue per share together and divide 10 will get our Cyclically Adjusted Revenue per Share.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

What does a Cyclically Adjusted PS Ratio of 2.85 mean?
Ono Pharmaceutical Co (MEX:4528N) has a Cyclically Adjusted PS Ratio of 2.85 as of Aug. 15, 2026. Cyclically Adjusted PS Ratio is the ratio of share price to a company's inflation-adjusted revenue per share over a 10-year period. View historical data on Ono Pharmaceutical Co and its competitors. This is 52% below median its historical median of 5.93. Over the past decade, Ono Pharmaceutical Co's Cyclically Adjusted PS Ratio has ranged from 2.05 to 10.51. According to the industry distribution chart, Ono Pharmaceutical Co ranks #452 out of 751 companies in the Drug Manufacturers industry, placing it in the top 60.2%.
Is Ono Pharmaceutical Co's Cyclically Adjusted PS Ratio too high?
Ono Pharmaceutical Co's current Cyclically Adjusted PS Ratio of 2.85 is 52% below median its 10-year median of 5.93. Over the past 10 years, this metric has ranged from a low of 2.05 to a high of 10.51. The Drug Manufacturers industry median Cyclically Adjusted PS Ratio is 2.04. Ono Pharmaceutical Co's value of 2.85 is 39.7% above this industry median. Based on the distribution chart, Ono Pharmaceutical Co ranks #452 out of 751 companies in the Drug Manufacturers industry, which is below the industry midpoint. Overall, Ono Pharmaceutical Co has a GF Score™ of 89/100, reflecting its overall financial health beyond just this single metric.
How does Ono Pharmaceutical Co's Cyclically Adjusted PS Ratio compare to LLY and JNJ?
According to the Drug Manufacturers industry distribution chart, Ono Pharmaceutical Co ranks #452 out of 751 companies for Cyclically Adjusted PS Ratio. This places Ono Pharmaceutical Co in the lower half of its industry. The industry median Cyclically Adjusted PS Ratio is 2.04. Ono Pharmaceutical Co's value of 2.85 is 39.7% above this benchmark. Historically, Ono Pharmaceutical Co's own Cyclically Adjusted PS Ratio has ranged from 2.05 to 10.51 over the past decade. While the company's 10-year median is 5.93 vs. the industry median of 2.04, Ono Pharmaceutical Co has consistently been above the industry average. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Cyclically Adjusted PS Ratio for a Drug Manufacturers company?
The median Cyclically Adjusted PS Ratio among Drug Manufacturers companies is 2.04, based on 751 companies in the industry. Companies in the top quartile (top 25%) have a Cyclically Adjusted PS Ratio significantly above this median, while those in the bottom quartile fall well below. However, Cyclically Adjusted PS Ratio should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Ono Pharmaceutical Co's current Cyclically Adjusted PS Ratio of 2.85 is 39.7% above the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Cyclically Adjusted PS Ratio mean?
A high Cyclically Adjusted PS Ratio can signal that a stock is expensive relative to its fundamentals. Cyclically Adjusted PS Ratio is the ratio of share price to a company's inflation-adjusted revenue per share over a 10-year period. View historical data on Ono Pharmaceutical Co and its competitors. For the Drug Manufacturers industry, the median Cyclically Adjusted PS Ratio is 2.04 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Ono Pharmaceutical Co's current Cyclically Adjusted PS Ratio is 2.85, which is 52% below median its own 10-year median of 5.93. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Ono Pharmaceutical Co stock overvalued right now?
Ono Pharmaceutical Co (MEX:4528N) has a current Cyclically Adjusted PS Ratio of 2.85. The stock's GF Value™ is MXN311.93, compared to a current price of MXN341.69 — trading 9.5% above its estimated fair value. The current Cyclically Adjusted PS Ratio is 2.85, which is 52% below median its 10-year median of 5.93 and 39.7% above the Drug Manufacturers industry median of 2.04. Ono Pharmaceutical Co's overall GF Score™ is 89/100 with 2 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Cyclically Adjusted PS Ratio calculated?
Cyclically Adjusted PS Ratio is calculated from a company's financial statements. For Ono Pharmaceutical Co (MEX:4528N), the current Cyclically Adjusted PS Ratio is 2.85 as of Aug. 15, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Ono Pharmaceutical Co (MEX:4528N) Overvalued in 2026?

Based on GuruFocus' analysis, Ono Pharmaceutical Co stock appears to be overvalued. The current stock price of MXN341.69 is trading 9.5% above its estimated GF Value™ of MXN311.93.

Key valuation signals for MEX:4528N:

  • Cyclically Adjusted PS Ratio: 2.85 (52% below median its 10-year median of 5.93)
  • GF Value™: MXN311.93 vs. price of MXN341.69 (9.5% above fair value)
  • GF Score™: 89/100 with 2 warning signs
  • Industry Position: 39.7% above the Drug Manufacturers median (#452 of 751)

No single metric tells the full story. See the MEX:4528N stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Ono Pharmaceutical Co Business Description

Address 1-8-2 Kyutarocho, Chuo-ku, Osaka, JPN, 541-8564
Ono Pharmaceutical Co Ltd is a drug manufacturer with a focus on drug discovery in areas of unmet medical needs. The vast majority of the company's revenue is derived from its circulatory and respiratory drugs, followed by its metabolic drugs and vitamins. The company also reports revenue derived from royalties. The bulk of the company's sales is generated in Japan, followed by the rest of Asia and Europe.
89GF Score

Get the complete analysis for MEX:4528N

Cyclically Adjusted PS Ratio is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

MXN341.69
Price
MXN311.93
GF Value