Ono Pharmaceutical CoMEX:4528N 88 Gross Margin % is 72.16% as of Mar. 2026, which is 1% below its 10-year median of 73.10. GuruFocus rates MEX:4528N with a GF Score™ of 88/100 and a GF Value™ of MXN324.16. The stock has 2 warning signs investors should review. Among 935 Drug Manufacturers companies, Ono Pharmaceutical Co ranks better than 84.92% on this metric.
MEX:4528N's Gross Margin % is ranked better than 84.92% of 935
companies
in the Drug Manufacturers industry
Industry Median: 48.54
vs MEX:4528N: 72.52
Ono Pharmaceutical Co had a gross margin of 72.16% for the quarter that ended in Mar. 2026 => Durable competitive advantage
The 5-Year average Growth Rate of Gross Margin for Ono Pharmaceutical Co was -0.50% per year.
Ono Pharmaceutical Co (MEX:4528N) Gross Margin % Explanation
Warren Buffett believes that firms with excellent long term economics tend to have consistently higher margins.
Durable competitive advantage creates a high Gross Margin % because of the freedom to price in excess of cost. Companies can be categorized by their Gross Margin %
1. Greater than 40% = Durable competitive advantage
2. Less than 40% = Competition eroding margins
3. Less than 20% = no sustainable competitive advantage
Consistency of Gross Margin is key
Ono Pharmaceutical Co had a gross margin of 72.16% for the quarter that ended in Mar. 2026 => Durable competitive advantage
Be Aware
If a company loses its competitive advantages, usually its gross margin declines well before its sales declines. Watching Gross Margin % and Operating Margin % closely helps avoid value trap situations.
Ono Pharmaceutical Co Gross Margin % Related Terms
Ono Pharmaceutical Co Gross Margin % Historical Data
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The historical data trend for Ono Pharmaceutical Co's Gross Margin % can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
MEX:4528N vs LLY, JNJ, ABBV: Gross Margin % Comparison
For the Drug Manufacturers - General subindustry, Ono Pharmaceutical Co's Gross Margin %, along with its competitors' market caps and Gross Margin % data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
Ono Pharmaceutical Co Gross Margin % vs Drug Manufacturers Industry
For the Drug Manufacturers industry and Healthcare sector, Ono Pharmaceutical Co's Gross Margin % distribution charts can be found below:
* The bar in red indicates where Ono Pharmaceutical Co's Gross Margin % falls into.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
A positive Gross Profit is only the first step for a company to make a net profit. The gross profit needs to be big enough to also cover related labor, equipment, rental, marketing/advertising, research and development and a lot of other costs in selling the products.
Ono Pharmaceutical Co (MEX:4528N) has a Gross Margin % of 72.16% as of Mar. 2026. Gross margin is the ratio of total gross profit to net sales. View historical data on Ono Pharmaceutical Co and its competitors. This is near median its historical median of 73.10. Over the past decade, Ono Pharmaceutical Co's Gross Margin % has ranged from 69.61 to 75.39. According to the industry distribution chart, Ono Pharmaceutical Co ranks #141 out of 935 companies in the Drug Manufacturers industry, placing it in the top 15.1%.
Is Ono Pharmaceutical Co's Gross Margin % too high?
Ono Pharmaceutical Co's current Gross Margin % of 72.16% is near median its 10-year median of 73.10. Over the past 10 years, this metric has ranged from a low of 69.61 to a high of 75.39. The Drug Manufacturers industry median Gross Margin % is 48.54. Ono Pharmaceutical Co's value of 72.16% is 48.7% above this industry median. Based on the distribution chart, Ono Pharmaceutical Co ranks #141 out of 935 companies in the Drug Manufacturers industry, which is in the top quartile — a strong position relative to peers. Overall, Ono Pharmaceutical Co has a GF Score™ of 88/100, reflecting its overall financial health beyond just this single metric.
How does Ono Pharmaceutical Co's Gross Margin % compare to LLY and JNJ?
According to the Drug Manufacturers industry distribution chart, Ono Pharmaceutical Co ranks #141 out of 935 companies for Gross Margin %. This places Ono Pharmaceutical Co in the top 15% of its industry — outperforming the majority of peers. The industry median Gross Margin % is 48.54. Ono Pharmaceutical Co's value of 72.16% is 48.7% above this benchmark. Historically, Ono Pharmaceutical Co's own Gross Margin % has ranged from 69.61 to 75.39 over the past decade. While the company's 10-year median is 73.10 vs. the industry median of 48.54, Ono Pharmaceutical Co has consistently been above the industry average. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Gross Margin % for a Drug Manufacturers company?
The median Gross Margin % among Drug Manufacturers companies is 48.54, based on 935 companies in the industry. Companies in the top quartile (top 25%) have a Gross Margin % significantly above this median, while those in the bottom quartile fall well below. However, Gross Margin % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Ono Pharmaceutical Co's current Gross Margin % of 72.16% is 48.7% above the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Gross Margin % mean?
A high Gross Margin % can signal that a stock is expensive relative to its fundamentals. Gross margin is the ratio of total gross profit to net sales. View historical data on Ono Pharmaceutical Co and its competitors. For the Drug Manufacturers industry, the median Gross Margin % is 48.54 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Ono Pharmaceutical Co's current Gross Margin % is 72.16%, which is near median its own 10-year median of 73.10. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Ono Pharmaceutical Co stock overvalued right now?
Ono Pharmaceutical Co (MEX:4528N) has a current Gross Margin % of 72.16%. The stock's GF Value™ is MXN324.16, compared to a current price of MXN341.69 — trading 5.4% above its estimated fair value. The current Gross Margin % is 72.16%, which is near median its 10-year median of 73.10 and 48.7% above the Drug Manufacturers industry median of 48.54. Ono Pharmaceutical Co's overall GF Score™ is 88/100 with 2 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Gross Margin % calculated?
Gross Margin % is calculated from a company's financial statements. For Ono Pharmaceutical Co (MEX:4528N), the current Gross Margin % is 72.16% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Is Ono Pharmaceutical Co (MEX:4528N) Overvalued in 2026?
Based on GuruFocus' analysis, Ono Pharmaceutical Co stock appears to be overvalued.
The current stock price of MXN341.69 is trading 5.4% above its estimated GF Value™ of MXN324.16.
Key valuation signals for MEX:4528N:
Gross Margin %: 72.16% (near median its 10-year median of 73.10)
GF Value™: MXN324.16 vs. price of MXN341.69 (5.4% above fair value)
Industry Position: 48.7% above the Drug Manufacturers median (#141 of 935)
No single metric tells the full story. See the MEX:4528N stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.
Ono Pharmaceutical Co Ltd is a drug manufacturer with a focus on drug discovery in areas of unmet medical needs. The vast majority of the company's revenue is derived from its circulatory and respiratory drugs, followed by its metabolic drugs and vitamins. The company also reports revenue derived from royalties. The bulk of the company's sales is generated in Japan, followed by the rest of Asia and Europe.
88GF Score
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