PharmaEngine (ROCO:4162) Cyclically Adjusted PS Ratio: 8.28 (As of Aug. 04, 2026) — 52% Below Median

Author: Vera Yuan Vera Yuan
Vera Yuan
Vera Yuan
Director of Data and Quant Analytics at GuruFocus
Focused on building reliable datasets, financial models, and research tools for value-minded investors. Committed to turning complex data into practical guidance for value-investing and long-term wealth.
Reviewed by: Charlie Tian Charlie Tian
Charlie Tian
Charlie Tian
Founder & CEO of GuruFocus
Dr. Charlie Tian is the founder and CEO of GuruFocus.com, a leading global investment research platform established in 2004. With a Ph.D. in physics, Dr. Tian transitioned from science to finance, applying a data-driven, disciplined approach to value investing.

ROCO:4162 PharmaEngine Inc ROCO:4162
83 GF Score
Price NT$63.00
GF Value NT$108.05
Valuation Possible Value Trap
! 4 Warning Signs
View Full Analysis

What is PharmaEngine Cyclically Adjusted PS Ratio?

PharmaEngine ROCO:4162 +1.61% 83 Cyclically Adjusted PS Ratio is 8.28 as of Aug. 04, 2026, which is 52% below its 10-year median of 17.24. GuruFocus rates ROCO:4162 with a GF Score™ of 83/100 and a GF Value™ of NT$108.05 (Possible Value Trap). The stock has 4 warning signs investors should review. Among 538 Biotechnology companies, PharmaEngine ranks worse than 59.11% on this metric.

As of today (2026-08-04), PharmaEngine's current share price is NT$63.00. PharmaEngine's Cyclically Adjusted Revenue per Share for the quarter that ended in Mar. 2026 was NT$7.61. PharmaEngine's Cyclically Adjusted PS Ratio for today is 8.28.

The historical rank and industry rank for PharmaEngine's Cyclically Adjusted PS Ratio or its related term are showing as below:

ROCO:4162' s Cyclically Adjusted PS Ratio Range Over the Past 10 Years
Min: 7.04   Med: 17.24   Max: 31.32
Current: 8.07

During the past years, PharmaEngine's highest Cyclically Adjusted PS Ratio was 31.32. The lowest was 7.04. And the median was 17.24.

ROCO:4162's Cyclically Adjusted PS Ratio is ranked worse than
59.11% of 538 companies
in the Biotechnology industry
Industry Median: 5.5 vs ROCO:4162: 8.07

The Shiller PE Ratio was first used by professor Robert Shiller. He uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings per share of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PS Ratio. The Cyclically Adjusted Revenue per Share is the average of the inflation adjusted revenue per share of a company over the past 10 years.

PharmaEngine's adjusted revenue per share data for the three months ended in Mar. 2026 was NT$1.667. Add all the adjusted revenue per share for the past 10 years together and divide 10 will get our Cyclically Adjusted Revenue per Share, which is NT$7.61 for the trailing ten years ended in Mar. 2026.

Shiller PE for Stocks: The True Measure of Stock Valuation


PharmaEngine  (ROCO:4162) Cyclically Adjusted PS Ratio Explanation

Compared with the regular PS Ratio, which works poorly for cyclical businesses, the Cyclically Adjusted PS Ratio smoothed out the fluctuations of revenue during business cycles. Therefore it is more accurate in reflecting the valuation of the company.

If a company has consistent business performance, the Cyclically Adjusted PS Ratio should give similar results to regular PS Ratio.


PharmaEngine Cyclically Adjusted PS Ratio Related Terms


PharmaEngine Cyclically Adjusted PS Ratio Historical Data

* Premium members only.

The historical data trend for PharmaEngine's Cyclically Adjusted PS Ratio can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

PharmaEngine Cyclically Adjusted PS Ratio Chart

PharmaEngine Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Cyclically Adjusted PS Ratio
Get a 7-Day Free Trial Premium Member Only Premium Member Only 17.81 27.18 20.09 12.99 9.64

PharmaEngine Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
Cyclically Adjusted PS Ratio Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 13.42 11.29 9.41 9.64 7.56

ROCO:4162 vs VRTX, REGN, RVMD: Cyclically Adjusted PS Ratio Comparison

For the Biotechnology subindustry, PharmaEngine's Cyclically Adjusted PS Ratio, along with its competitors' market caps and Cyclically Adjusted PS Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


PharmaEngine Cyclically Adjusted PS Ratio vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, PharmaEngine's Cyclically Adjusted PS Ratio distribution charts can be found below:

* The bar in red indicates where PharmaEngine's Cyclically Adjusted PS Ratio falls into.


ROCO:4162
83GF Score
PharmaEngine Inc ROCO:4162
Cyclically Adjusted PS Ratio is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

PharmaEngine Cyclically Adjusted PS Ratio Calculation

Like the Shiller PE Ratio, the Cyclically Adjusted PS Ratio takes the Revenue per Share from the past 10 years, adjusts it for inflation, and then calculates the average. This average is then used for the P/S calculation. Because it considers this 10-year average, it's often referred to as the CAPS Ratio.

The Shiller PE Ratio was first used by professor Robert Shiller to measure the valuation of the overall market. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PS Ratio.

PharmaEngine's Cyclically Adjusted PS Ratio for today is calculated as

Cyclically Adjusted PS Ratio=Share Price/ Cyclically Adjusted Revenue per Share
=63.00/7.61
=8.28

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

PharmaEngine's Cyclically Adjusted Revenue per Share for the quarter that ended in Mar. 2026 is calculated as:

For example, PharmaEngine's adjusted Revenue per Share data for the three months ended in Mar. 2026 was:

Adj_RevenuePerShare=Revenue per Share/CPI of Mar. 2026 (Change)*Current CPI (Mar. 2026)
=1.667/330.2130*330.2130
=1.667

Current CPI (Mar. 2026) = 330.2130.

PharmaEngine Quarterly Data

Revenue per Share CPI Adj_RevenuePerShare
201606 2.643 241.018 3.621
201609 0.019 241.428 0.026
201612 5.453 241.432 7.458
201703 0.074 243.801 0.100
201706 0.197 244.955 0.266
201709 0.163 246.819 0.218
201712 5.238 246.524 7.016
201803 0.230 249.554 0.304
201806 0.289 251.989 0.379
201809 0.937 252.439 1.226
201812 0.531 251.233 0.698
201903 0.534 254.202 0.694
201906 0.556 256.143 0.717
201909 0.551 256.759 0.709
201912 0.514 256.974 0.660
202003 0.575 258.115 0.736
202006 0.619 257.797 0.793
202009 0.676 260.280 0.858
202012 5.365 260.474 6.801
202103 0.793 264.877 0.989
202106 1.089 271.696 1.324
202109 1.235 274.310 1.487
202112 1.418 278.802 1.679
202203 1.212 287.504 1.392
202206 1.159 296.311 1.292
202209 1.080 296.808 1.202
202212 1.103 296.797 1.227
202303 1.171 301.836 1.281
202306 1.150 305.109 1.245
202309 1.705 307.789 1.829
202312 1.303 306.746 1.403
202403 1.144 312.332 1.209
202406 1.830 314.175 1.923
202409 1.515 315.301 1.587
202412 13.014 315.605 13.616
202503 1.302 319.799 1.344
202506 1.328 322.561 1.360
202509 1.686 324.800 1.714
202512 1.979 324.054 2.017
202603 1.667 330.213 1.667

Add all the adjusted revenue per share together and divide 10 will get our Cyclically Adjusted Revenue per Share.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

What does a Cyclically Adjusted PS Ratio of 8.28 mean?
PharmaEngine (ROCO:4162) has a Cyclically Adjusted PS Ratio of 8.28 as of Aug. 04, 2026. Cyclically Adjusted PS Ratio is the ratio of share price to a company's inflation-adjusted revenue per share over a 10-year period. View historical data on PharmaEngine and its competitors. This is 52% below median its historical median of 17.24. Over the past decade, PharmaEngine's Cyclically Adjusted PS Ratio has ranged from 7.04 to 31.32. According to the industry distribution chart, PharmaEngine ranks #318 out of 538 companies in the Biotechnology industry, placing it in the top 59.1%.
Is PharmaEngine's Cyclically Adjusted PS Ratio too high?
PharmaEngine's current Cyclically Adjusted PS Ratio of 8.28 is 52% below median its 10-year median of 17.24. Over the past 10 years, this metric has ranged from a low of 7.04 to a high of 31.32. The Biotechnology industry median Cyclically Adjusted PS Ratio is 5.50. PharmaEngine's value of 8.28 is 50.5% above this industry median. Based on the distribution chart, PharmaEngine ranks #318 out of 538 companies in the Biotechnology industry, which is below the industry midpoint. Overall, PharmaEngine has a GF Score™ of 83/100 and is considered Possible Value Trap, reflecting its overall financial health beyond just this single metric.
How does PharmaEngine's Cyclically Adjusted PS Ratio compare to VRTX and REGN?
According to the Biotechnology industry distribution chart, PharmaEngine ranks #318 out of 538 companies for Cyclically Adjusted PS Ratio. This places PharmaEngine in the lower half of its industry. The industry median Cyclically Adjusted PS Ratio is 5.50. PharmaEngine's value of 8.28 is 50.5% above this benchmark. Historically, PharmaEngine's own Cyclically Adjusted PS Ratio has ranged from 7.04 to 31.32 over the past decade. While the company's 10-year median is 17.24 vs. the industry median of 5.50, PharmaEngine has consistently been above the industry average. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Cyclically Adjusted PS Ratio for a Biotechnology company?
The median Cyclically Adjusted PS Ratio among Biotechnology companies is 5.50, based on 538 companies in the industry. Companies in the top quartile (top 25%) have a Cyclically Adjusted PS Ratio significantly above this median, while those in the bottom quartile fall well below. However, Cyclically Adjusted PS Ratio should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. PharmaEngine's current Cyclically Adjusted PS Ratio of 8.28 is 50.5% above the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Cyclically Adjusted PS Ratio mean?
A high Cyclically Adjusted PS Ratio can signal that a stock is expensive relative to its fundamentals. Cyclically Adjusted PS Ratio is the ratio of share price to a company's inflation-adjusted revenue per share over a 10-year period. View historical data on PharmaEngine and its competitors. For the Biotechnology industry, the median Cyclically Adjusted PS Ratio is 5.50 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. PharmaEngine's current Cyclically Adjusted PS Ratio is 8.28, which is 52% below median its own 10-year median of 17.24. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is PharmaEngine stock overvalued right now?
Based on GuruFocus' analysis, PharmaEngine (ROCO:4162) is currently considered Possible Value Trap. The stock's GF Value™ is NT$108.05, compared to a current price of NT$63.00 — trading 41.7% below its estimated fair value. The current Cyclically Adjusted PS Ratio is 8.28, which is 52% below median its 10-year median of 17.24 and 50.5% above the Biotechnology industry median of 5.50. PharmaEngine's overall GF Score™ is 83/100 with 4 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Cyclically Adjusted PS Ratio calculated?
Cyclically Adjusted PS Ratio is calculated from a company's financial statements. For PharmaEngine (ROCO:4162), the current Cyclically Adjusted PS Ratio is 8.28 as of Aug. 04, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is PharmaEngine (ROCO:4162) Overvalued in 2026?

Based on GuruFocus' analysis, PharmaEngine stock appears to be undervalued. The current stock price of NT$63.00 is trading 41.7% below its estimated GF Value™ of NT$108.05. GuruFocus considers PharmaEngine to be Possible Value Trap.

Key valuation signals for ROCO:4162:

  • Cyclically Adjusted PS Ratio: 8.28 (52% below median its 10-year median of 17.24)
  • GF Value™: NT$108.05 vs. price of NT$63.00 (41.7% below fair value)
  • GF Score™: 83/100 with 4 warning signs
  • Industry Position: 50.5% above the Biotechnology median (#318 of 538)

No single metric tells the full story. See the ROCO:4162 stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


PharmaEngine Business Description

Address No. 10, Minsheng East Road, 11th Floor, Section 3, Taipei, TWN, 104
PharmaEngine Inc is a biopharmaceutical company engaged in the development of new drugs and therapeutic drugs for cancer. It is a specialty pharma company that adopts the no research, development-only model and the networked pharma model for new drug development. Its key products and pipeline projects include ONIVYDE, a treatment for metastatic pancreatic cancer approved in multiple markets, as well as oncology candidates such as PEP07 and PEP08. It generates revenue from the sales of goods.
83GF Score

Get the complete analysis for ROCO:4162

Cyclically Adjusted PS Ratio is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

NT$63.00
Price
NT$108.05
GF Value