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PharmaEngineROCO:4162 -4.07%83 Return-on-Tangible-Equity is 10.79% as of Dec. 2025, which is 18% above its 10-year median of 9.11. GuruFocus rates ROCO:4162 with a GF Score™ of 83/100 and a GF Value™ of NT$115.66 (Significantly Undervalued). The stock has 3 warning signs investors should review. Among 1,200 Biotechnology companies, PharmaEngine ranks better than 84.58% on this metric.
Return-on-Tangible-Equity is calculated as Net Income divided by its average total shareholder tangible equity. Total shareholder tangible equity equals to Total Stockholders Equity minus Intangible Assets. PharmaEngine's annualized net income for the quarter that ended in Dec. 2025 was NT$524.4 Mil. PharmaEngine's average shareholder tangible equity for the quarter that ended in Dec. 2025 was NT$4,859.2 Mil. Therefore, PharmaEngine's annualized Return-on-Tangible-Equity for the quarter that ended in Dec. 2025 was 10.79%.
The historical rank and industry rank for PharmaEngine's Return-on-Tangible-Equity or its related term are showing as below:
ROCO:4162'
s Return-on-Tangible-Equity Range Over the Past 10 Years
Min: 1.19 Med: 9.11 Max: 37.82
Current: 7.67
During the past 13 years, PharmaEngine's highest Return-on-Tangible-Equity was 37.82%. The lowest was 1.19%. And the median was 9.11%.
ROCO:4162's Return-on-Tangible-Equity is ranked better than 84.58% of 1200
companies
in the Biotechnology industry
Industry Median: -42.435
vs ROCO:4162: 7.67
Return-on-Tangible-Equity measures the rate of return on the ownership interest (shareholder's tangible equity) of the common stock owners. It measures a firm's efficiency at generating profits from every unit of shareholders' tangible equity (shareholders equity minus intangibles). Return-on-Tangible-Equity shows how well a company uses investment funds to generate earnings growth. Return-on-Tangible-Equitys between 15% and 20% are considered desirable.
Be Aware
Net Income is used.
Because a company can increase its Return-on-Tangible-Equity by having more financial leverage, it is important to watch the leverage ratio when investing in high Return-on-Tangible-Equity companies. Like Return-on-Tangible-Asset, Return-on-Tangible-Equity is calculated with only 12 months data. Fluctuations in company's earnings or business cycles can affect the ratio drastically. It is important to look at the ratio from a long term perspective.
Asset light businesses require very few assets to generate very high earnings. Their Return-on-Tangible-Equitys can be extremely high.
PharmaEngine Return-on-Tangible-Equity Related Terms
PharmaEngine Return-on-Tangible-Equity Historical Data
* Premium members only.
The historical data trend for PharmaEngine's Return-on-Tangible-Equity can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
ROCO:4162 vs VRTX, REGN, ALNY: Return-on-Tangible-Equity Comparison
For the Biotechnology subindustry, PharmaEngine's Return-on-Tangible-Equity, along with its competitors' market caps and Return-on-Tangible-Equity data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
PharmaEngine Return-on-Tangible-Equity vs Biotechnology Industry
For the Biotechnology industry and Healthcare sector, PharmaEngine's Return-on-Tangible-Equity distribution charts can be found below:
* The bar in red indicates where PharmaEngine's Return-on-Tangible-Equity falls into.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
In the calculation of annual Return-on-Tangible-Equity, the net income of the last fiscal year and the average total shareholder tangible equity over the fiscal year are used. In calculating the quarterly data,
the net income data used here is four times the quarterly (Dec. 2025) net income data.
Return-on-Tangible-Equity is displayed in the 10-year financial page.
What does a Return-on-Tangible-Equity of 10.79% mean?
PharmaEngine (ROCO:4162) has a Return-on-Tangible-Equity of 10.79% as of Dec. 2025. Return on tangible equity is the ratio of current-period net income to average two-period tangible equity. View historical data on PharmaEngine and its competitors. This is 18% above median its historical median of 9.11. Over the past decade, PharmaEngine's Return-on-Tangible-Equity has ranged from 1.19 to 37.82. According to the industry distribution chart, PharmaEngine ranks #185 out of 1200 companies in the Biotechnology industry, placing it in the top 15.4%.
Is PharmaEngine's Return-on-Tangible-Equity too high?
PharmaEngine's current Return-on-Tangible-Equity of 10.79% is 18% above median its 10-year median of 9.11. Over the past 10 years, this metric has ranged from a low of 1.19 to a high of 37.82. Based on the distribution chart, PharmaEngine ranks #185 out of 1200 companies in the Biotechnology industry, which is in the top quartile — a strong position relative to peers. Overall, PharmaEngine has a GF Score™ of 83/100 and is considered Significantly Undervalued, reflecting its overall financial health beyond just this single metric.
How does PharmaEngine's Return-on-Tangible-Equity compare to VRTX and REGN?
According to the Biotechnology industry distribution chart, PharmaEngine ranks #185 out of 1200 companies for Return-on-Tangible-Equity. This places PharmaEngine in the top 15% of its industry — outperforming the majority of peers. Historically, PharmaEngine's own Return-on-Tangible-Equity has ranged from 1.19 to 37.82 over the past decade. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Return-on-Tangible-Equity for a Biotechnology company?
A good Return-on-Tangible-Equity depends on the Biotechnology industry context. However, Return-on-Tangible-Equity should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Return-on-Tangible-Equity mean?
A high Return-on-Tangible-Equity can signal that a stock is expensive relative to its fundamentals. Return on tangible equity is the ratio of current-period net income to average two-period tangible equity. View historical data on PharmaEngine and its competitors. PharmaEngine's current Return-on-Tangible-Equity is 10.79%, which is 18% above median its own 10-year median of 9.11. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is PharmaEngine stock overvalued right now?
Based on GuruFocus' analysis, PharmaEngine (ROCO:4162) is currently considered Significantly Undervalued. The stock's GF Value™ is NT$115.66, compared to a current price of NT$63.70 — trading 44.9% below its estimated fair value. The current Return-on-Tangible-Equity is 10.79%, which is 18% above median its 10-year median of 9.11. PharmaEngine's overall GF Score™ is 83/100 with 3 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Return-on-Tangible-Equity calculated?
Return-on-Tangible-Equity is calculated from a company's financial statements. For PharmaEngine (ROCO:4162), the current Return-on-Tangible-Equity is 10.79% as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Is PharmaEngine (ROCO:4162) Overvalued in 2026?
Based on GuruFocus' analysis, PharmaEngine stock appears to be undervalued.
The current stock price of NT$63.70 is trading 44.9% below its estimated GF Value™ of NT$115.66.
GuruFocus considers PharmaEngine to be Significantly Undervalued.
Key valuation signals for ROCO:4162:
Return-on-Tangible-Equity: 10.79% (18% above median its 10-year median of 9.11)
GF Value™: NT$115.66 vs. price of NT$63.70 (44.9% below fair value)
No single metric tells the full story. See the ROCO:4162 stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.
PharmaEngine Inc is a biopharmaceutical company engaged in the development of new drugs and therapeutic drugs for cancer. It is a specialty pharma company that adopts the no research, development-only model and the networked pharma model for new drug development. Its key products and pipeline projects include ONIVYDE, a treatment for metastatic pancreatic cancer approved in multiple markets, as well as oncology candidates such as PEP07 and PEP08. It generates revenue from the sales of goods.
83GF Score
Get the complete analysis for ROCO:4162
Return-on-Tangible-Equity is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.
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