PharmaEngine (ROCO:4162) E10: NT$3.98 (As of Dec. 2025)


ROCO:4162 PharmaEngine Inc ROCO:4162
79 GF Score
Price NT$61.00
GF Value NT$115.04
Valuation Significantly Undervalued
! 3 Warning Signs
View Full Analysis

What is PharmaEngine E10?

PharmaEngine ROCO:4162 +2.52% 79 E10 is NT$3.98 as of Dec. 2025. GuruFocus rates ROCO:4162 with a GF Score™ of 79/100 and a GF Value™ of NT$115.04 (Significantly Undervalued). The stock has 3 warning signs investors should review.

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller P/E calculation. E10 is the average of the inflation adjusted earnings of a company over the past 10 years.

PharmaEngine's adjusted earnings per share data for the three months ended in Dec. 2025 was NT$0.910. Add all the adjusted EPS for the past 10 years together and divide 10 will get our e10, which is NT$3.98 for the trailing ten years ended in Dec. 2025.

During the past 12 months, PharmaEngine's average E10 Growth Rate was 0.50% per year. During the past 3 years, the average E10 Growth Rate was 18.50% per year. During the past 5 years, the average E10 Growth Rate was 17.30% per year. Please click Growth Rate Calculation Example (GuruFocus) to see how GuruFocus calculates Wal-Mart Stores Inc (WMT)'s revenue growth rate. You can apply the same method to get the E10 growth rate using E10 data.

During the past 13 years, the highest 3-Year average E10 Growth Rate of PharmaEngine was 23.90% per year. The lowest was 12.00% per year. And the median was 18.50% per year.

As of today (2026-07-01), PharmaEngine's current stock price is NT$61.00. PharmaEngine's E10 for the quarter that ended in Dec. 2025 was NT$3.98. PharmaEngine's Shiller PE Ratio of today is 15.33.

During the past 13 years, the highest Shiller PE Ratio of PharmaEngine was 62.79. The lowest was 13.47. And the median was 33.13.


PharmaEngine  (ROCO:4162) E10 Explanation

If a company grows much fast than inflation, E10 may underestimate the company's earnings power. Shiller PE Ratio can seem to be too high even the actual P/E is low.

For the Shiller P/E, the earnings of the past 10 years are inflation-adjusted and averaged. The result is used for P/E calculation. Since it looks at the average over the last 10 years, the Shiller P/E is also called PE10.

The Shiller P/E was first used by professor Robert Shiller to measure the valuation of the overall market. The same calculation is applied here to individual companies.

PharmaEngine's Shiller P/E Ratio of today is calculated as

Shiller PE Ratio=Share Price/E10
=61.00/3.98
=15.33

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

During the past 13 years, the highest Shiller P/E Ratio of PharmaEngine was 62.79. The lowest was 13.47. And the median was 33.13.


Be Aware

Shiller PE Ratio works better for cyclical companies. It gives you a better idea on the company's real earnings power.


PharmaEngine E10 Related Terms


PharmaEngine E10 Historical Data

* Premium members only.

The historical data trend for PharmaEngine's E10 can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

PharmaEngine E10 Chart

PharmaEngine Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
E10
Get a 7-Day Free Trial Premium Member Only Premium Member Only 2.08 2.39 2.77 3.96 3.98

PharmaEngine Quarterly Data
Mar21 Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25
E10 Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 3.96 4.12 3.78 3.87 3.98

ROCO:4162 vs VRTX, REGN, ALNY: E10 Comparison

For the Biotechnology subindustry, PharmaEngine's Shiller PE Ratio, along with its competitors' market caps and Shiller PE Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


PharmaEngine Shiller PE Ratio vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, PharmaEngine's Shiller PE Ratio distribution charts can be found below:

* The bar in red indicates where PharmaEngine's Shiller PE Ratio falls into.


ROCO:4162
79GF Score
PharmaEngine Inc ROCO:4162
E10 is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

PharmaEngine E10 Calculation

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller P/E calculation. When we calculate the today's Shiller P/E ratio of a stock, we use today's price divided by E10.

What is E10? How do we calculate E10?

E10 is the average of the inflation adjusted earnings of a company over the past 10 years. Let's use an example to explain.

If we want to calculate the E10 of Wal-Mart (WMT) for Dec. 31, 2010, we need to have the inflation data and the earnings from 2001 through 2010.

We adjusted the earnings of 2001 earnings data with the total inflation from 2001 through 2010 to the equivalent earnings in 2010. If the total inflation from 2001 to 2010 is 40%, and Wal-Mart earned $1 a share in 2001, then the 2001's equivalent earnings in 2010 is $1.4 a share. If Wal-Mart earns $1 again in 2002, and the total inflation from 2002 through 2010 is 35%, then the equivalent 2002 earnings in 2010 is $1.35. So on and so forth, you get the equivalent earnings of past 10 years. Then you add them together and divided the sum by 10 to get E10.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

For example, PharmaEngine's adjusted earnings per share data for the three months ended in Dec. 2025 was:

Adj_EPS= Earnings per Share (Diluted) /CPI of Dec. 2025 (Change)*Current CPI (Dec. 2025)
=0.91/324.0540*324.0540
=0.910

Current CPI (Dec. 2025) = 324.0540.

PharmaEngine Quarterly Data

per share eps CPI Adj_EPS
201603 -0.350 238.132 -0.476
201606 1.692 241.018 2.275
201609 -0.620 241.428 -0.832
201612 4.190 241.432 5.624
201703 -0.850 243.801 -1.130
201706 -0.240 244.955 -0.317
201709 -0.020 246.819 -0.026
201712 3.740 246.524 4.916
201803 -0.330 249.554 -0.429
201806 0.480 251.989 0.617
201809 0.500 252.439 0.642
201812 0.230 251.233 0.297
201903 0.190 254.202 0.242
201906 0.200 256.143 0.253
201909 0.160 256.759 0.202
201912 -0.260 256.974 -0.328
202003 0.340 258.115 0.427
202006 0.010 257.797 0.013
202009 0.130 260.280 0.162
202012 3.580 260.474 4.454
202103 0.520 264.877 0.636
202106 1.140 271.696 1.360
202109 0.510 274.310 0.602
202112 0.770 278.802 0.895
202203 0.680 287.504 0.766
202206 0.560 296.311 0.612
202209 0.610 296.808 0.666
202212 0.370 296.797 0.404
202303 0.570 301.836 0.612
202306 0.520 305.109 0.552
202309 0.560 307.789 0.590
202312 0.260 306.746 0.275
202403 0.570 312.332 0.591
202406 1.110 314.175 1.145
202409 0.640 315.301 0.658
202412 9.860 315.605 10.124
202503 0.710 319.799 0.719
202506 0.120 322.561 0.121
202509 0.950 324.800 0.948
202512 0.910 324.054 0.910

Add all the adjusted EPS together and divide 10 will get our e10.

Frequently Asked Questions Learn more about E10 →
What does a E10 of NT$3.98 mean?
PharmaEngine (ROCO:4162) has a E10 of NT$3.98 as of Dec. 2025. E10 represents the company's inflation-adjusted earnings per share over a 10-year period. View historical data on PharmaEngine and its competitors.
Is PharmaEngine's E10 too high?
PharmaEngine's current E10 is NT$3.98. Overall, PharmaEngine has a GF Score™ of 79/100 and is considered Significantly Undervalued, reflecting its overall financial health beyond just this single metric.
How does PharmaEngine's E10 compare to VRTX and REGN?
PharmaEngine's E10 of NT$3.98 can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good E10 for a Biotechnology company?
A good E10 depends on the Biotechnology industry context. However, E10 should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high E10 mean?
A high E10 can signal that a stock is expensive relative to its fundamentals. E10 represents the company's inflation-adjusted earnings per share over a 10-year period. View historical data on PharmaEngine and its competitors. PharmaEngine's current E10 is NT$3.98. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is PharmaEngine stock overvalued right now?
Based on GuruFocus' analysis, PharmaEngine (ROCO:4162) is currently considered Significantly Undervalued. The stock's GF Value™ is NT$115.04, compared to a current price of NT$61.00 — trading 47% below its estimated fair value. The current E10 is NT$3.98. PharmaEngine's overall GF Score™ is 79/100 with 3 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is E10 calculated?
E10 is calculated from a company's financial statements. For PharmaEngine (ROCO:4162), the current E10 is NT$3.98 as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is PharmaEngine (ROCO:4162) Overvalued in 2026?

Based on GuruFocus' analysis, PharmaEngine stock appears to be undervalued. The current stock price of NT$61.00 is trading 47% below its estimated GF Value™ of NT$115.04. GuruFocus considers PharmaEngine to be Significantly Undervalued.

Key valuation signals for ROCO:4162:

  • E10: NT$3.98
  • GF Value™: NT$115.04 vs. price of NT$61.00 (47% below fair value)
  • GF Score™: 79/100 with 3 warning signs

No single metric tells the full story. See the ROCO:4162 stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


PharmaEngine Business Description

Address No. 10, Minsheng East Road, 11th Floor, Section 3, Taipei, TWN, 104
PharmaEngine Inc is a biopharmaceutical company engaged in the development of new drugs and therapeutic drugs for cancer. It is a specialty pharma company that adopts the no research, development-only model and the networked pharma model for new drug development. Its key products and pipeline projects include ONIVYDE, a treatment for metastatic pancreatic cancer approved in multiple markets, as well as oncology candidates such as PEP07 and PEP08. It generates revenue from the sales of goods.
79GF Score

Get the complete analysis for ROCO:4162

E10 is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

NT$61.00
Price
NT$115.04
GF Value