VYNE (VYNE Therapeutics) Cyclically Adjusted Revenue per Share: $483.20 (As of Mar. 2026)

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VYNE VYNE Therapeutics Inc VYNE
59 GF Score
Price $27.86
GF Value $29.06
Valuation Fairly Valued
! 4 Warning Signs
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What is VYNE Therapeutics Cyclically Adjusted Revenue per Share?

VYNE Therapeutics VYNE +10.91% 59 Cyclically Adjusted Revenue per Share is $483.20 as of Mar. 2026. GuruFocus rates VYNE with a GF Score™ of 59/100 and a GF Value™ of $29.06 (Fairly Valued). The stock has 4 warning signs investors should review.

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted Revenue per Share and the Cyclically Adjusted PS Ratio. The Cyclically Adjusted Revenue per Share is the average of the inflation adjusted Revenue per Share of a company over the past 10 years.

VYNE Therapeutics's adjusted revenue per share data for the fiscal year that ended in Dec. 2025 was $0.667. Add all the adjusted revenue per share for the past 10 years together and divide the count will get our Cyclically Adjusted Revenue per Share, which is $483.20 for the trailing ten years ended in Dec. 2025.

Please click Growth Rate Calculation Example (GuruFocus) to see how GuruFocus calculates Wal-Mart Stores Inc (WMT)'s revenue growth rate. You can apply the same method to get the Cyclically Adjusted Revenue Growth Rate using Cyclically Adjusted Revenue per Share data.

As of today (2026-07-28), VYNE Therapeutics's current stock price is $ 27.855. VYNE Therapeutics's Cyclically Adjusted Revenue per Share for the fiscal year that ended in Dec. 2025 was $483.20. VYNE Therapeutics's Cyclically Adjusted PS Ratio of today is 0.06.

During the past 11 years, the highest Cyclically Adjusted PS Ratio of VYNE Therapeutics was 0.33. The lowest was 0.06. And the median was 0.12.


VYNE Therapeutics  (NAS:VYNE) Cyclically Adjusted Revenue per Share Explanation

If a company grows much fast than inflation, Cyclically Adjusted Revenue per Share may underestimate the company's revenue. Cyclically Adjusted PS Ratio can seem to be too high even the actual PS Ratio is low.

For the Cyclically Adjusted PS Ratio, the revenue per share of the past 10 years are inflation-adjusted and averaged. The result is used for P/S calculation. Since it looks at the average over the last 10 years, the Cyclically Adjusted PS Ratio is also called CAPS Ratio.

The Shiller PE Ratio was first used by professor Robert Shiller. He uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings per share of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PS Ratio. The Cyclically Adjusted Revenue per Share is the average of the inflation adjusted revenue per share of a company over the past 10 years.

VYNE Therapeutics's Cyclically Adjusted PS Ratio of today is calculated as

Cyclically Adjusted PS Ratio=Share Price/Cyclically Adjusted Revenue per Share
=27.855/483.20
=0.06

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

During the past 11 years, the highest Cyclically Adjusted PS Ratio of VYNE Therapeutics was 0.33. The lowest was 0.06. And the median was 0.12.


Be Aware

Cyclically Adjusted PS Ratio works better for cyclical companies. It gives you a better idea on the company's real revenue value.


VYNE Therapeutics Cyclically Adjusted Revenue per Share Related Terms


VYNE Therapeutics Cyclically Adjusted Revenue per Share Historical Data

* Premium members only.

The historical data trend for VYNE Therapeutics's Cyclically Adjusted Revenue per Share can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

VYNE Therapeutics Cyclically Adjusted Revenue per Share Chart

VYNE Therapeutics Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Cyclically Adjusted Revenue per Share
Get a 7-Day Free Trial Premium Member Only Premium Member Only 0.00 0.00 0.00 529.34 483.20

VYNE Therapeutics Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
Cyclically Adjusted Revenue per Share Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 0.00 0.00 0.00 483.20 0.00

VYNE vs NXTC, LPCN, QNCX: Cyclically Adjusted Revenue per Share Comparison

For the Biotechnology subindustry, VYNE Therapeutics's Cyclically Adjusted PS Ratio, along with its competitors' market caps and Cyclically Adjusted PS Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


VYNE Therapeutics Cyclically Adjusted PS Ratio vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, VYNE Therapeutics's Cyclically Adjusted PS Ratio distribution charts can be found below:

* The bar in red indicates where VYNE Therapeutics's Cyclically Adjusted PS Ratio falls into.


VYNE
59GF Score
VYNE Therapeutics Inc VYNE
Cyclically Adjusted Revenue per Share is just one metric. See GF Score™, valuation, warning signs, and more.
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VYNE Therapeutics Cyclically Adjusted Revenue per Share Calculation

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted Revenue per Share and the Cyclically Adjusted PS Ratio. The Cyclically Adjusted Revenue per Share is the average of the inflation adjusted Revenue per Share of a company over the past 10 years.

What is Cyclically Adjusted Revenue per Share? How do we calculate Cyclically Adjusted Revenue per Share?

Cyclically Adjusted Revenue per Share is the average of the inflation adjusted Revenue per Share of a company over the past 10 years. Let's use an example to explain.

If we want to calculate the Cyclically Adjusted Revenue per Share of Wal-Mart (WMT) for Dec. 31, 2010, we need to have the inflation data and the revenue per share from 2001 through 2010.

We adjusted the 2001 revenue per share data with the total inflation from 2001 through 2010 to the equivalent revenue in 2010. If the total inflation from 2001 to 2010 is 40%, and Wal-Mart's revenue is $1 a share in 2001, then the 2001's equivalent revenue in 2010 is $1.4 a share. If Wal-Mart's revenue is $1 again in 2002, and the total inflation from 2002 through 2010 is 35%, then the equivalent 2002 revenue in 2010 is $1.35. So on and so forth, you get the equivalent revenue per share of past 10 years. Then you add them together and divided the sum by the count to get Cyclically Adjusted Revenue per Share.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

For example, VYNE Therapeutics's adjusted Revenue per Share data for the fiscal year that ended in Dec. 2025 was:

Adj_RevenuePerShare=Revenue per Share /CPI of Dec. 2025 (Change)*Current CPI (Dec. 2025)
=0.667/324.0540*324.0540
=0.667

Current CPI (Dec. 2025) = 324.0540.

VYNE Therapeutics Annual Data

Revenue per Share CPI Adj_RevenuePerShare
201612 224.667 241.432 301.552
201712 763.667 246.524 1,003.835
201812 1,773.333 251.233 2,287.341
201912 0.000 256.974 0.000
202012 583.139 260.474 725.479
202112 16.333 278.802 18.984
202212 7.453 296.797 8.137
202312 2.068 306.746 2.185
202412 0.588 315.605 0.604
202512 0.667 324.054 0.667

Add all the adjusted revenue per share together and divide 10 will get our Cyclically Adjusted Revenue per Share.

What does a Cyclically Adjusted Revenue per Share of $483.20 mean?
VYNE Therapeutics (VYNE) has a Cyclically Adjusted Revenue per Share of $483.20 as of Mar. 2026. Cyclically adjusted revenue per share represents the company's inflation-adjusted revenue per share over a 10-year period. View historical data on VYNE Therapeutics and its competitors.
Is VYNE Therapeutics' Cyclically Adjusted Revenue per Share too high?
VYNE Therapeutics' current Cyclically Adjusted Revenue per Share is $483.20. Overall, VYNE Therapeutics has a GF Score™ of 59/100 and is considered Fairly Valued, reflecting its overall financial health beyond just this single metric.
How does VYNE Therapeutics' Cyclically Adjusted Revenue per Share compare to NXTC and LPCN?
VYNE Therapeutics' Cyclically Adjusted Revenue per Share of $483.20 can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Cyclically Adjusted Revenue per Share for a Biotechnology company?
A good Cyclically Adjusted Revenue per Share depends on the Biotechnology industry context. However, Cyclically Adjusted Revenue per Share should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Cyclically Adjusted Revenue per Share mean?
A high Cyclically Adjusted Revenue per Share can signal that a stock is expensive relative to its fundamentals. Cyclically adjusted revenue per share represents the company's inflation-adjusted revenue per share over a 10-year period. View historical data on VYNE Therapeutics and its competitors. VYNE Therapeutics's current Cyclically Adjusted Revenue per Share is $483.20. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is VYNE Therapeutics stock overvalued right now?
Based on GuruFocus' analysis, VYNE Therapeutics (VYNE) is currently considered Fairly Valued. The stock's GF Value™ is $29.06, compared to a current price of $27.86 — trading 4.1% below its estimated fair value. The current Cyclically Adjusted Revenue per Share is $483.20. VYNE Therapeutics' overall GF Score™ is 59/100 with 4 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Cyclically Adjusted Revenue per Share calculated?
Cyclically Adjusted Revenue per Share is calculated from a company's financial statements. For VYNE Therapeutics (VYNE), the current Cyclically Adjusted Revenue per Share is $483.20 as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is VYNE Therapeutics (VYNE) Overvalued in 2026?

Based on GuruFocus' analysis, VYNE Therapeutics stock appears to be undervalued. The current stock price of $27.86 is trading 4.1% below its estimated GF Value™ of $29.06. GuruFocus considers VYNE Therapeutics to be Fairly Valued.

Key valuation signals for VYNE:

  • Cyclically Adjusted Revenue per Share: $483.20
  • GF Value™: $29.06 vs. price of $27.86 (4.1% below fair value)
  • GF Score™: 59/100 with 4 warning signs

No single metric tells the full story. See the VYNE stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


VYNE Therapeutics Business Description

Address P.O. Box 125, Stewartsville, NJ, USA, 08886
VYNE Therapeutics Inc is a biopharmaceutical company focused on developing proprietary and differentiated therapies for the treatment of immuno-inflammatory conditions. The company is also in the pre-clinical stages of research, develop and commercialize products containing small molecule bromodomain and extra-terminal domain (BET) inhibitors for the treatment of any disease, disorder or condition in human. Its products include AMZEEQ, ZILXI, and FCD105.
59GF Score

Get the complete analysis for VYNE

Cyclically Adjusted Revenue per Share is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$27.86
Price
$29.06
GF Value