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A high Debt-to-EBITDA ratio generally means that a company may spend more time to paying off its debt. According to Joel Tillinghast's BIG MONEY THINKS SMALL: Biases, Blind Spots, and Smarter Investing, a ratio of Debt-to-EBITDA exceeding four is usually considered scary unless tangible assets cover the debt.
The historical rank and industry rank for HCW Biologics's Debt-to-EBITDA or its related term are showing as below:
HCWB'
s Debt-to-EBITDA Range Over the Past 10 Years
Min: -17.68 Med: -0.48 Max: -0.27
Current: -17.68
During the past 7 years, the highest Debt-to-EBITDA Ratio of HCW Biologics was -0.27. The lowest was -17.68. And the median was -0.48.
HCWB's Debt-to-EBITDA is ranked worse than 100% of 291
companies
in the Biotechnology industry
Industry Median: 1.14
vs HCWB: -17.68
A high Debt-to-EBITDA ratio generally means that a company may spend more time to paying off its debt.
According to Joel Tillinghast's BIG MONEY THINKS SMALL: Biases, Blind Spots, and Smarter Investing, a ratio of Debt-to-EBITDA exceeding four is usually considered scary unless tangible assets cover the debt.
HCW Biologics Debt-to-EBITDA Related Terms
HCW Biologics Debt-to-EBITDA Historical Data
* Premium members only.
The historical data trend for HCW Biologics's Debt-to-EBITDA can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
HCWB vs KAPA, IMNN, MTVA: Debt-to-EBITDA Comparison
For the Biotechnology subindustry, HCW Biologics's Debt-to-EBITDA, along with its competitors' market caps and Debt-to-EBITDA data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
HCW Biologics Debt-to-EBITDA vs Biotechnology Industry
For the Biotechnology industry and Healthcare sector, HCW Biologics's Debt-to-EBITDA distribution charts can be found below:
* The bar in red indicates where HCW Biologics's Debt-to-EBITDA falls into.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
In the calculation of annual Debt-to-EBITDA, the EBITDA of the last fiscal year is used. In calculating the annualized quarterly data,
the EBITDA data used here is four times the quarterly (Mar. 2026) EBITDA data.
HCW Biologics (HCWB) has a Debt-to-EBITDA of 0.40 as of Mar. 2026. Debt-to-EBITDA ratio represents the ratio of total debt to total earnings before interest, taxes, depreciation and amortization. View historical data on HCW Biologics. According to the industry distribution chart, HCW Biologics ranks #999999 out of 291 companies in the Biotechnology industry.
Is HCW Biologics' Debt-to-EBITDA too high?
HCW Biologics' current Debt-to-EBITDA is 0.40. The Biotechnology industry median Debt-to-EBITDA is 1.14. HCW Biologics' value of 0.40 is 64.9% below this industry median. Based on the distribution chart, HCW Biologics ranks #999999 out of 291 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, HCW Biologics has a GF Score™ of 38/100 and is considered Possible Value Trap, reflecting its overall financial health beyond just this single metric.
How does HCW Biologics' Debt-to-EBITDA compare to KAPA and IMNN?
According to the Biotechnology industry distribution chart, HCW Biologics ranks #999999 out of 291 companies for Debt-to-EBITDA. This places HCW Biologics in the lower half of its industry. The industry median Debt-to-EBITDA is 1.14. HCW Biologics' value of 0.40 is 64.9% below this benchmark. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Debt-to-EBITDA for a Biotechnology company?
The median Debt-to-EBITDA among Biotechnology companies is 1.14, based on 291 companies in the industry. Companies in the top quartile (top 25%) have a Debt-to-EBITDA significantly above this median, while those in the bottom quartile fall well below. However, Debt-to-EBITDA should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. HCW Biologics's current Debt-to-EBITDA of 0.40 is 64.9% below the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Debt-to-EBITDA mean?
A high Debt-to-EBITDA can signal that a stock is expensive relative to its fundamentals. Debt-to-EBITDA ratio represents the ratio of total debt to total earnings before interest, taxes, depreciation and amortization. View historical data on HCW Biologics. For the Biotechnology industry, the median Debt-to-EBITDA is 1.14 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. HCW Biologics's current Debt-to-EBITDA is 0.40. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is HCW Biologics stock overvalued right now?
Based on GuruFocus' analysis, HCW Biologics (HCWB) is currently considered Possible Value Trap. The stock's GF Value™ is $43.75, compared to a current price of $4.50 — trading 89.7% below its estimated fair value. The current Debt-to-EBITDA is 0.40 and 64.9% below the Biotechnology industry median of 1.14. HCW Biologics' overall GF Score™ is 38/100 with 7 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Debt-to-EBITDA calculated?
Debt-to-EBITDA is calculated from a company's financial statements. For HCW Biologics (HCWB), the current Debt-to-EBITDA is 0.40 as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Is HCW Biologics (HCWB) Overvalued in 2026?
Based on GuruFocus' analysis, HCW Biologics stock appears to be undervalued.
The current stock price of $4.50 is trading 89.7% below its estimated GF Value™ of $43.75.
GuruFocus considers HCW Biologics to be Possible Value Trap.
Key valuation signals for HCWB:
Debt-to-EBITDA: 0.40
GF Value™: $43.75 vs. price of $4.50 (89.7% below fair value)
Industry Position: 64.9% below the Biotechnology median (#999999 of 291)
No single metric tells the full story. See the HCWB stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.
HCW Biologics Inc is a clinical-stage biopharmaceutical company developing transformative fusion immunotherapeutics to support or treat diseases promoted by chronic inflammation. It has created novel compounds that represent a new class of drugs that it believes has the potential to fundamentally change the treatment of autoimmune disorders and other proinflammatory diseases, cancer and senescence-associated dysplasia. The company has developed two proprietary drug discovery and development platforms which it uses to create novel fusion immunotherapeutics: The TOBI (Tissue factOr-Based fusIon) platform, and The T-cell Receptor Beta Chain constant region (TRBC) platform. It operates and manages its business as one reportable segment.
38GF Score
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