OXFYY (Oxford Nanopore Technologies) Debt-to-EBITDA : -0.49 (As of Dec. 2025)

Author: Vera Yuan Vera Yuan
Vera Yuan
Vera Yuan
Director of Data and Quant Analytics at GuruFocus
Focused on building reliable datasets, financial models, and research tools for value-minded investors. Committed to turning complex data into practical guidance for value-investing and long-term wealth.
Reviewed by: Charlie Tian Charlie Tian
Charlie Tian
Charlie Tian
Founder & CEO of GuruFocus
Dr. Charlie Tian is the founder and CEO of GuruFocus.com, a leading global investment research platform established in 2004. With a Ph.D. in physics, Dr. Tian transitioned from science to finance, applying a data-driven, disciplined approach to value investing.

OXFYY Oxford Nanopore Technologies PLC OXFYY
50 GF Score
Price $6.50
GF Value $10.34
Valuation Significantly Undervalued
! 2 Warning Signs
View Full Analysis

What is Oxford Nanopore Technologies Debt-to-EBITDA?

Oxford Nanopore Technologies OXFYY -11.92% 50 Debt-to-EBITDA is -0.49 as of Dec. 2025. GuruFocus rates OXFYY with a GF Score™ of 50/100 and a GF Value™ of $10.34 (Significantly Undervalued). The stock has 2 warning signs investors should review. Among 291 Biotechnology companies, Oxford Nanopore Technologies ranks worse than 343642.27% on this metric.

Debt-to-EBITDA measures a company's ability to pay off its debt.

Oxford Nanopore Technologies's Short-Term Debt & Capital Lease Obligation for the quarter that ended in Dec. 2025 was $7.0 Mil. Oxford Nanopore Technologies's Long-Term Debt & Capital Lease Obligation for the quarter that ended in Dec. 2025 was $48.6 Mil. Oxford Nanopore Technologies's annualized EBITDA for the quarter that ended in Dec. 2025 was $-114.3 Mil. Oxford Nanopore Technologies's annualized Debt-to-EBITDA for the quarter that ended in Dec. 2025 was -0.49.

A high Debt-to-EBITDA ratio generally means that a company may spend more time to paying off its debt. According to Joel Tillinghast's BIG MONEY THINKS SMALL: Biases, Blind Spots, and Smarter Investing, a ratio of Debt-to-EBITDA exceeding four is usually considered scary unless tangible assets cover the debt.

The historical rank and industry rank for Oxford Nanopore Technologies's Debt-to-EBITDA or its related term are showing as below:

OXFYY' s Debt-to-EBITDA Range Over the Past 10 Years
Min: -0.68   Med: -0.41   Max: -0.17
Current: -0.48

During the past 8 years, the highest Debt-to-EBITDA Ratio of Oxford Nanopore Technologies was -0.17. The lowest was -0.68. And the median was -0.41.

OXFYY's Debt-to-EBITDA is ranked worse than
100% of 291 companies
in the Biotechnology industry
Industry Median: 1.14 vs OXFYY: -0.48

Oxford Nanopore Technologies  (OTCPK:OXFYY) Debt-to-EBITDA Explanation

In the calculation of Debt-to-EBITDA, we use the total of Short-Term Debt & Capital Lease Obligation and Long-Term Debt & Capital Lease Obligation divided by EBITDA. In some calculations, Total Liabilities is used to for calculation.


Be Aware

A high Debt-to-EBITDA ratio generally means that a company may spend more time to paying off its debt.

According to Joel Tillinghast's BIG MONEY THINKS SMALL: Biases, Blind Spots, and Smarter Investing, a ratio of Debt-to-EBITDA exceeding four is usually considered scary unless tangible assets cover the debt.


Oxford Nanopore Technologies Debt-to-EBITDA Related Terms


Oxford Nanopore Technologies Debt-to-EBITDA Historical Data

* Premium members only.

The historical data trend for Oxford Nanopore Technologies's Debt-to-EBITDA can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Oxford Nanopore Technologies Debt-to-EBITDA Chart

Oxford Nanopore Technologies Annual Data
Trend Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Debt-to-EBITDA
Get a 7-Day Free Trial -0.18 -0.68 -0.39 -0.49 -0.48

Oxford Nanopore Technologies Semi-Annual Data
Dec18 Dec19 Jun20 Dec20 Jun21 Dec21 Jun22 Dec22 Jun23 Dec23 Jun24 Dec24 Jun25 Dec25
Debt-to-EBITDA Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -0.35 -0.47 -0.53 -0.49 -0.49

OXFYY vs VRTX, REGN, ALNY: Debt-to-EBITDA Comparison

For the Biotechnology subindustry, Oxford Nanopore Technologies's Debt-to-EBITDA, along with its competitors' market caps and Debt-to-EBITDA data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Oxford Nanopore Technologies Debt-to-EBITDA vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Oxford Nanopore Technologies's Debt-to-EBITDA distribution charts can be found below:

* The bar in red indicates where Oxford Nanopore Technologies's Debt-to-EBITDA falls into.


OXFYY
50GF Score
Oxford Nanopore Technologies PLC OXFYY
Debt-to-EBITDA is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

Oxford Nanopore Technologies Debt-to-EBITDA Calculation

Debt-to-EBITDA measures a company's ability to pay off its debt.

Oxford Nanopore Technologies's Debt-to-EBITDA for the fiscal year that ended in Dec. 2025 is calculated as

Debt-to-EBITDA=Total Debt / EBITDA
=(Short-Term Debt & Capital Lease Obligation + Long-Term Debt & Capital Lease Obligation) / EBITDA
=(6.961 + 48.594) / -116.867
=-0.48

Oxford Nanopore Technologies's annualized Debt-to-EBITDA for the quarter that ended in Dec. 2025 is calculated as

Debt-to-EBITDA=Total Debt / EBITDA
=(Short-Term Debt & Capital Lease Obligation + Long-Term Debt & Capital Lease Obligation) / EBITDA
=(6.961 + 48.594) / -114.324
=-0.49

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

In the calculation of annual Debt-to-EBITDA, the EBITDA of the last fiscal year is used. In calculating the annualized quarterly data, the EBITDA data used here is two times the quarterly (Dec. 2025) EBITDA data.

Frequently Asked Questions Learn more about Debt-to-EBITDA →
What does a Debt-to-EBITDA of -0.49 mean?
Oxford Nanopore Technologies (OXFYY) has a Debt-to-EBITDA of -0.49 as of Dec. 2025. Debt-to-EBITDA ratio represents the ratio of total debt to total earnings before interest, taxes, depreciation and amortization. View historical data on Oxford Nanopore Technologies. According to the industry distribution chart, Oxford Nanopore Technologies ranks #999999 out of 291 companies in the Biotechnology industry.
Is Oxford Nanopore Technologies' Debt-to-EBITDA too high?
Oxford Nanopore Technologies' current Debt-to-EBITDA is -0.49. Based on the distribution chart, Oxford Nanopore Technologies ranks #999999 out of 291 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, Oxford Nanopore Technologies has a GF Score™ of 50/100 and is considered Significantly Undervalued, reflecting its overall financial health beyond just this single metric.
How does Oxford Nanopore Technologies' Debt-to-EBITDA compare to VRTX and REGN?
According to the Biotechnology industry distribution chart, Oxford Nanopore Technologies ranks #999999 out of 291 companies for Debt-to-EBITDA. This places Oxford Nanopore Technologies in the lower half of its industry. The industry median Debt-to-EBITDA is 1.14. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Debt-to-EBITDA for a Biotechnology company?
The median Debt-to-EBITDA among Biotechnology companies is 1.14, based on 291 companies in the industry. Companies in the top quartile (top 25%) have a Debt-to-EBITDA significantly above this median, while those in the bottom quartile fall well below. However, Debt-to-EBITDA should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Debt-to-EBITDA mean?
A high Debt-to-EBITDA can signal that a stock is expensive relative to its fundamentals. Debt-to-EBITDA ratio represents the ratio of total debt to total earnings before interest, taxes, depreciation and amortization. View historical data on Oxford Nanopore Technologies. For the Biotechnology industry, the median Debt-to-EBITDA is 1.14 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Oxford Nanopore Technologies's current Debt-to-EBITDA is -0.49. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Oxford Nanopore Technologies stock overvalued right now?
Based on GuruFocus' analysis, Oxford Nanopore Technologies (OXFYY) is currently considered Significantly Undervalued. The stock's GF Value™ is $10.34, compared to a current price of $6.50 — trading 37.1% below its estimated fair value. The current Debt-to-EBITDA is -0.49. Oxford Nanopore Technologies' overall GF Score™ is 50/100 with 2 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Debt-to-EBITDA calculated?
Debt-to-EBITDA is calculated from a company's financial statements. For Oxford Nanopore Technologies (OXFYY), the current Debt-to-EBITDA is -0.49 as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Oxford Nanopore Technologies (OXFYY) Overvalued in 2026?

Based on GuruFocus' analysis, Oxford Nanopore Technologies stock appears to be undervalued. The current stock price of $6.50 is trading 37.1% below its estimated GF Value™ of $10.34. GuruFocus considers Oxford Nanopore Technologies to be Significantly Undervalued.

Key valuation signals for OXFYY:

  • Debt-to-EBITDA: -0.49
  • GF Value™: $10.34 vs. price of $6.50 (37.1% below fair value)
  • GF Score™: 50/100 with 2 warning signs

No single metric tells the full story. See the OXFYY stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Oxford Nanopore Technologies Business Description

Address Edmund Halley Road, Gosling Building, Oxford Science Park, Oxford, Oxfordshire, GBR, OX4 4DQ
Oxford Nanopore Technologies PLC is involved in researching, developing, manufacturing and commercializing deoxyribonucleic acid (DNA) or ribonucleic acid (RNA) sequencing technology that provides rich data, is fast, accessible and easy to use, and which allows the real-time analysis of DNA or RNA. It has developed and brought to market a new generation molecular sensing platform based on nanopores. The first application is DNA/RNA sequencing and the platform is also being developed for the analysis of proteins and metabolites. It operates in single segment of providing products and services related to the sale and use of its nanopore-based sensing technology. Geographically its operations are spread across EMES, AMR, and APAC.
50GF Score

Get the complete analysis for OXFYY

Debt-to-EBITDA is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$6.50
Price
$10.34
GF Value